{"id":"https://openalex.org/W4387930644","doi":"https://doi.org/10.1186/s40001-023-01438-3","title":"Intravascular laser irradiation of blood as novel migraine treatment: an observational study","display_name":"Intravascular laser irradiation of blood as novel migraine treatment: an observational study","publication_year":2023,"publication_date":"2023-10-25","ids":{"openalex":"https://openalex.org/W4387930644","doi":"https://doi.org/10.1186/s40001-023-01438-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/37876003","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10598972"},"language":"en","primary_location":{"id":"doi:10.1186/s40001-023-01438-3","doi":"https://doi.org/10.1186/s40001-023-01438-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40001-023-01438-3","pdf_url":"https://eurjmedres.biomedcentral.com/counter/pdf/10.1186/s40001-023-01438-3","source":{"id":"https://openalex.org/S64516541","display_name":"European journal of medical research","issn_l":"0949-2321","issn":["0949-2321","2047-783X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Medical Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://eurjmedres.biomedcentral.com/counter/pdf/10.1186/s40001-023-01438-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055968744","display_name":"Hsin-Hung Chen","orcid":"https://orcid.org/0000-0002-5662-5945","observed_orcids":["https://orcid.org/0000-0002-5662-5945"]},"institutions":[{"id":"https://openalex.org/I4210152230","display_name":"Kaohsiung Veterans General Hospital","ror":"https://ror.org/04jedda80","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210152230"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hsin-Hung Chen","raw_affiliation_strings":["Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, 813414, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, 813414, Taiwan","institution_ids":["https://openalex.org/I4210152230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023781877","display_name":"Chun\u2010Yu Lin","orcid":"https://orcid.org/0000-0003-2901-2681","observed_orcids":["https://orcid.org/0000-0003-2901-2681","https://orcid.org/0000-0003-2847-0349"]},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chun-Yu Lin","raw_affiliation_strings":["College of Photonics, National Yang Ming Chiao Tung University, Tainan, 71150, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Photonics, National Yang Ming Chiao Tung University, Tainan, 71150, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076721217","display_name":"Shean\u2010Jen Chen","orcid":"https://orcid.org/0000-0002-9648-9466","observed_orcids":["https://orcid.org/0000-0002-9648-9466"]},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I4210166867","display_name":"National Institutes of Applied Research","ror":"https://ror.org/05wcstg80","country_code":"TW","type":"government","lineage":["https://openalex.org/I4210128167","https://openalex.org/I4210166867"]},{"id":"https://openalex.org/I4405282297","display_name":"National Center for Instrumentation Research","ror":"https://ror.org/05mraaf88","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210128167","https://openalex.org/I4210166867","https://openalex.org/I4405282297"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Shean-Jen Chen","raw_affiliation_strings":["College of Photonics, National Yang Ming Chiao Tung University, Tainan, 71150, Taiwan","Taiwan Instrument Research Institute, National Applied Research Laboratories, Hsinchu, 300092, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Photonics, National Yang Ming Chiao Tung University, Tainan, 71150, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Taiwan Instrument Research Institute, National Applied Research Laboratories, Hsinchu, 300092, Taiwan","institution_ids":["https://openalex.org/I4210166867","https://openalex.org/I4405282297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054016025","display_name":"Wan-Yun Huang","orcid":"https://orcid.org/0000-0003-3552-4077","observed_orcids":["https://orcid.org/0000-0003-3552-4077"]},"institutions":[{"id":"https://openalex.org/I4210152230","display_name":"Kaohsiung Veterans General Hospital","ror":"https://ror.org/04jedda80","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210152230"]},{"id":"https://openalex.org/I91807558","display_name":"National Cheng Kung University","ror":"https://ror.org/01b8kcc49","country_code":"TW","type":"education","lineage":["https://openalex.org/I91807558"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Wan-Yun Huang","raw_affiliation_strings":["Department of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Zuoying Dist, # 386, Dazhong 1St Rd, Kaohsiung, 813414, Taiwan","Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, 70119, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Zuoying Dist, # 386, Dazhong 1St Rd, Kaohsiung, 813414, Taiwan","institution_ids":["https://openalex.org/I4210152230"]},{"raw_affiliation_string":"Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, 70119, Taiwan","institution_ids":["https://openalex.org/I91807558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102571350","display_name":"Chien-Wei Kuo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405272440","display_name":"Pingtung Veterans General Hospital","ror":"https://ror.org/045xv9g95","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4405272440"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chien-Wei Kuo","raw_affiliation_strings":["Department of Nuclear Medicine, Pingtung Veterans General Hospital, Pingtung 900, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Pingtung Veterans General Hospital, Pingtung 900, Taiwan","institution_ids":["https://openalex.org/I4405272440"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002767387","display_name":"Shin\u2010Tsu Chang","orcid":"https://orcid.org/0000-0003-4005-2094","observed_orcids":["https://orcid.org/0000-0003-4005-2094"]},"institutions":[{"id":"https://openalex.org/I1293718874","display_name":"Tri-Service General Hospital","ror":"https://ror.org/007h4qe29","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I1293718874"]},{"id":"https://openalex.org/I4210152230","display_name":"Kaohsiung Veterans General Hospital","ror":"https://ror.org/04jedda80","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210152230"]},{"id":"https://openalex.org/I68171755","display_name":"National Defense Medical Center","ror":"https://ror.org/02bn97g32","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I68171755"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Shin-Tsu Chang","raw_affiliation_strings":["Department of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Zuoying Dist, # 386, Dazhong 1St Rd, Kaohsiung, 813414, Taiwan. ccdivlaser1959@gmail.com","Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Neihu District, # 161, Section 6, Minquan East Road, Taipei, 114201, Taiwan. ccdivlaser1959@gmail.com","Department of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Zuoying Dist, # 386, Dazhong 1St Rd, Kaohsiung, 813414, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Zuoying Dist, # 386, Dazhong 1St Rd, Kaohsiung, 813414, Taiwan. ccdivlaser1959@gmail.com","institution_ids":["https://openalex.org/I4210152230"]},{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Neihu District, # 161, Section 6, Minquan East Road, Taipei, 114201, Taiwan. ccdivlaser1959@gmail.com","institution_ids":["https://openalex.org/I1293718874","https://openalex.org/I68171755"]},{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Zuoying Dist, # 386, Dazhong 1St Rd, Kaohsiung, 813414, Taiwan","institution_ids":["https://openalex.org/I4210152230"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5002767387"],"corresponding_institution_ids":["https://openalex.org/I1293718874","https://openalex.org/I4210152230","https://openalex.org/I68171755"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":2.5862,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.89845205,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"28","issue":"1","first_page":"457","last_page":"457"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10498","display_name":"Migraine and Headache Studies","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11566","display_name":"Laser Applications in Dentistry and Medicine","score":0.021700000390410423,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11327","display_name":"Acupuncture Treatment Research Studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/migraine","display_name":"migraine","score":0.984000027179718},{"id":"https://openalex.org/keywords/intravascular-laser-irradiation-of-blood","display_name":"intravascular laser irradiation of blood","score":0.9679999947547913},{"id":"https://openalex.org/keywords/low-level-laser-therapy","display_name":"low-level laser therapy","score":0.953000009059906},{"id":"https://openalex.org/keywords/regional-cerebral-blood-flow","display_name":"regional cerebral blood flow","score":0.9409999847412109},{"id":"https://openalex.org/keywords/spect-imaging","display_name":"SPECT imaging","score":0.7820000052452087},{"id":"https://openalex.org/keywords/headache","display_name":"headache","score":0.6759999990463257},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.9079999923706055},{"id":"https://openalex.org/keywords/insomnia","display_name":"insomnia","score":0.6899999976158142}],"concepts":[{"id":"https://openalex.org/C2778541695","wikidata":"https://www.wikidata.org/wiki/Q133823","display_name":"Migraine","level":2,"score":0.8511337041854858},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8401578664779663},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.6095677614212036},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.5667240023612976},{"id":"https://openalex.org/C2780441642","wikidata":"https://www.wikidata.org/wiki/Q849737","display_name":"Single-photon emission computed tomography","level":2,"score":0.5400356650352478},{"id":"https://openalex.org/C14184104","wikidata":"https://www.wikidata.org/wiki/Q1362526","display_name":"Visual analogue scale","level":2,"score":0.5230644345283508},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.43971094489097595},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.40349042415618896},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36565154790878296},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3334423899650574}],"mesh":[{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008881","descriptor_name":"Migraine Disorders","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D015899","descriptor_name":"Tomography, Emission-Computed, Single-Photon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D053685","descriptor_name":"Laser Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s40001-023-01438-3","doi":"https://doi.org/10.1186/s40001-023-01438-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40001-023-01438-3","pdf_url":"https://eurjmedres.biomedcentral.com/counter/pdf/10.1186/s40001-023-01438-3","source":{"id":"https://openalex.org/S64516541","display_name":"European journal of medical research","issn_l":"0949-2321","issn":["0949-2321","2047-783X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Medical Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10598972","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10598972","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10598972/pdf/40001_2023_Article_1438.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eur J Med Res","raw_type":"Text"},{"id":"pmid:37876003","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37876003","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of medical research","raw_type":"Observational Study"},{"id":"pmh:oai:doaj.org/article:07898babbac143108136e39d1bb4aba9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/07898babbac143108136e39d1bb4aba9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"European Journal of Medical Research, Vol 28, Iss 1, Pp 1-8 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s40001-023-01438-3","doi":"https://doi.org/10.1186/s40001-023-01438-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s40001-023-01438-3","pdf_url":"https://eurjmedres.biomedcentral.com/counter/pdf/10.1186/s40001-023-01438-3","source":{"id":"https://openalex.org/S64516541","display_name":"European journal of medical research","issn_l":"0949-2321","issn":["0949-2321","2047-783X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Medical Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1818293323","display_name":"The Effects of Low-Energy Intravenous Laser Irradiation of Blood on Cerebral Blood Flow and Neurological Dysfunction in Ischemic Stroke Patients and Possible Physiological Regulatory Mechanisms","funder_award_id":"NSTC112-2314-B075B-011","funder_id":"https://openalex.org/F2461203286","funder_display_name":"National Science and Technology Council"},{"id":"https://openalex.org/G2491407383","display_name":null,"funder_award_id":"KSVGH111-152","funder_id":"https://openalex.org/F4320327359","funder_display_name":"Kaohsiung Veterans General Hospital"},{"id":"https://openalex.org/G2885402746","display_name":"Molecular Mechanisms of Serum and Glucocorticoid-Regulated Kinase 1 Underlying Central Cardiovascular Regulation in Brain Stem Nuclei of Hypertensive Rats","funder_award_id":"MOST110-2320-B075B-001-MY3","funder_id":"https://openalex.org/F4320322795","funder_display_name":"Ministry of Science and Technology, Taiwan"},{"id":"https://openalex.org/G4517693462","display_name":null,"funder_award_id":"and KSVGH112-115","funder_id":"https://openalex.org/F4320327359","funder_display_name":"Kaohsiung Veterans General Hospital"},{"id":"https://openalex.org/G6099622703","display_name":null,"funder_award_id":"KSVGH110-172, KSVGH111-166, and KSVGH112-115","funder_id":"https://openalex.org/F4320327359","funder_display_name":"Kaohsiung Veterans General Hospital"},{"id":"https://openalex.org/G7571172244","display_name":null,"funder_award_id":"KSVGH111-166","funder_id":"https://openalex.org/F4320327359","funder_display_name":"Kaohsiung Veterans General Hospital"},{"id":"https://openalex.org/G85062315","display_name":null,"funder_award_id":"KSVGH110-172","funder_id":"https://openalex.org/F4320327359","funder_display_name":"Kaohsiung Veterans General Hospital"}],"funders":[{"id":"https://openalex.org/F2461203286","display_name":"National Science and Technology Council","ror":"https://ror.org/02kv4zf79"},{"id":"https://openalex.org/F4320322795","display_name":"Ministry of Science and Technology, Taiwan","ror":"https://ror.org/02kv4zf79"},{"id":"https://openalex.org/F4320323440","display_name":"University System of Taiwan","ror":"https://ror.org/054kvr030"},{"id":"https://openalex.org/F4320327359","display_name":"Kaohsiung Veterans General Hospital","ror":"https://ror.org/04jedda80"},{"id":"https://openalex.org/F4320331164","display_name":"National Science and Technology Council","ror":"https://ror.org/00wnb9798"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387930644.pdf","grobid_xml":"https://content.openalex.org/works/W4387930644.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W46438429","https://openalex.org/W1987355656","https://openalex.org/W2013484881","https://openalex.org/W2031436922","https://openalex.org/W2045530969","https://openalex.org/W2052258972","https://openalex.org/W2058688388","https://openalex.org/W2064698815","https://openalex.org/W2084866959","https://openalex.org/W2096181241","https://openalex.org/W2099358732","https://openalex.org/W2103293821","https://openalex.org/W2111605706","https://openalex.org/W2123704431","https://openalex.org/W2134116761","https://openalex.org/W2156846198","https://openalex.org/W2211514998","https://openalex.org/W2518034921","https://openalex.org/W2557973065","https://openalex.org/W2571772949","https://openalex.org/W2611652667","https://openalex.org/W2939449854","https://openalex.org/W3040708923","https://openalex.org/W3041325928","https://openalex.org/W3084499749","https://openalex.org/W3107747907","https://openalex.org/W3176179751","https://openalex.org/W3184167640","https://openalex.org/W4200039154","https://openalex.org/W4205187819","https://openalex.org/W4224234068","https://openalex.org/W4228996549","https://openalex.org/W4292567110","https://openalex.org/W4366597777","https://openalex.org/W4378234687"],"related_works":["https://openalex.org/W2057640870","https://openalex.org/W2392626280","https://openalex.org/W2029648706","https://openalex.org/W3206952423","https://openalex.org/W1984263541","https://openalex.org/W2772881220","https://openalex.org/W2366107674","https://openalex.org/W7100297208","https://openalex.org/W2366780111","https://openalex.org/W2367238460"],"abstract_inverted_index":{"BACKGROUND:":[0],"Migraine":[1],"is":[2,25,194],"one":[3],"of":[4,47,52],"four":[5],"major":[6],"chronic":[7],"diseases":[8],"that":[9],"cause":[10],"disability.":[11],"Decreases":[12],"in":[13,28,36,56,67,108,177,186],"regional":[14],"cerebral":[15],"blood":[16,53],"flow":[17],"(rCBF)":[18],"occur":[19],"during":[20],"migraine":[21,37,224],"attacks.":[22],"Laser":[23],"therapy":[24,55,193,226],"extensively":[26],"employed":[27],"treating":[29],"other":[30],"vascular":[31,200],"diseases;":[32],"nevertheless,":[33],"its":[34],"effectiveness":[35],"management":[38],"remains":[39],"largely":[40],"unknown.":[41],"Therefore,":[42],"we":[43],"evaluated":[44],"the":[45,101,187],"effect":[46],"low-level":[48],"intravascular":[49],"laser":[50,225],"irradiation":[51],"(ILIB)":[54],"patients":[57,69,122,127],"with":[58,196],"migraine.":[59,72,210],"METHODS:":[60],"We":[61],"performed":[62,88],"an":[63,77],"observational":[64],"case-control":[65],"study":[66,87],"24":[68],"suffering":[70],"from":[71,132],"Patients":[73],"were":[74,115,130],"divided":[75],"into":[76],"ILIB":[78,129,139,180,192],"treatment":[79,102,207],"group":[80],"and":[81,91,99,103,112,125,155,182,199,202],"a":[82,171,205,220],"traditional":[83],"rehabilitation":[84,124,188],"group.":[85,189],"This":[86],"clinical":[89,118,198],"assessments":[90],"single-photon":[92],"emission":[93],"computed":[94],"tomography":[95],"(SPECT)":[96],"prior":[97],"to":[98,117,134],"after":[100,166,179],"1":[104,135],"month":[105,136],"later.":[106],"Changes":[107],"rCBF-SPECT":[109],"between":[110,113],"groups":[111],"timepoints":[114],"compared":[116],"outcomes.":[119],"RESULTS:":[120],"Nine":[121],"undergoing":[123,128],"fifteen":[126],"studied":[131],"baseline":[133],"follow-up.":[137],"The":[138],"group,":[140],"visual":[141],"analog":[142],"scale":[143],"for":[144,209,223],"pain":[145],"(P":[146,152,159],"=":[147,153],"0.001),":[148],"Montreal":[149],"Cognitive":[150],"Assessment":[151],"0.003),":[154],"Athens":[156],"Insomnia":[157],"Scale":[158],"<":[160],"0.001)":[161],"symptom":[162],"scores":[163],"significantly":[164],"improved":[165],"treatment.":[167],"SPECT":[168],"imaging":[169],"showed":[170],"1.27":[172],"\u00b1":[173],"0.27":[174],"fold":[175],"increase":[176],"rCBF":[178],"treatment,":[181],"no":[183],"significant":[184],"differences":[185],"CONCLUSIONS:":[190],"Low-level":[191],"associated":[195],"better":[197],"outcomes,":[201],"may":[203],"be":[204],"feasible":[206],"option":[208],"Although":[211],"our":[212,217],"sample":[213],"size":[214],"was":[215],"small,":[216],"data":[218],"provide":[219],"starting":[221],"point":[222],"research.":[227]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-10-26T00:00:00"}