{"id":"https://openalex.org/W4387918322","doi":"https://doi.org/10.1039/d3tb01769a","title":"A pH-responsive supramolecular hydrogel encapsulating a CuMnS nanoenzyme catalyst for synergistic photothermal\u2013photodynamic\u2013chemodynamic therapy of tumours","display_name":"A pH-responsive supramolecular hydrogel encapsulating a CuMnS nanoenzyme catalyst for synergistic photothermal\u2013photodynamic\u2013chemodynamic therapy of tumours","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4387918322","doi":"https://doi.org/10.1039/d3tb01769a","pmid":"https://pubmed.ncbi.nlm.nih.gov/37917009"},"language":"en","primary_location":{"id":"doi:10.1039/d3tb01769a","doi":"https://doi.org/10.1039/d3tb01769a","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d3tb01769a","pdf_url":null,"source":{"id":"https://openalex.org/S2479884170","display_name":"Journal of Materials Chemistry B","issn_l":"2050-750X","issn":["2050-750X","2050-7518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Chemistry B","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114093733","display_name":"Anqin Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113613","display_name":"Fifth Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/01wfgh551","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210113613"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Anqin Dong","raw_affiliation_strings":["Department of Vascular Surgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Vascular Surgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, People's Republic of China","institution_ids":["https://openalex.org/I4210113613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101081026","display_name":"Shiwei Huang","orcid":"https://orcid.org/0000-0001-9603-9441","observed_orcids":["https://orcid.org/0000-0001-9603-9441"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shiwei Huang","raw_affiliation_strings":["School of Materials Science and Engineering, Tongji University, Shanghai 201804, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Materials Science and Engineering, Tongji University, Shanghai 201804, People's Republic of China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069549452","display_name":"Zhiyi Qian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiyi Qian","raw_affiliation_strings":["School of Materials Science and Engineering, Tongji University, Shanghai 201804, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Materials Science and Engineering, Tongji University, Shanghai 201804, People's Republic of China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113329086","display_name":"Sicheng Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sicheng Xu","raw_affiliation_strings":["School of Materials Science and Engineering, Tongji University, Shanghai 201804, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Materials Science and Engineering, Tongji University, Shanghai 201804, People's Republic of China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074728970","display_name":"Weizhong Yuan","orcid":"https://orcid.org/0000-0002-5981-9366","observed_orcids":["https://orcid.org/0000-0002-5981-9366"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210113613","display_name":"Fifth Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/01wfgh551","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210113613"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Weizhong Yuan","raw_affiliation_strings":["Department of Vascular Surgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, People's Republic of China","School of Materials Science and Engineering, Tongji University, Shanghai 201804, People's Republic of China"],"raw_orcid":"https://orcid.org/0000-0002-5981-9366","affiliations":[{"raw_affiliation_string":"Department of Vascular Surgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, People's Republic of China","institution_ids":["https://openalex.org/I4210113613"]},{"raw_affiliation_string":"School of Materials Science and Engineering, Tongji University, Shanghai 201804, People's Republic of China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100382537","display_name":"Bing Wang","orcid":"https://orcid.org/0000-0003-0237-1107","observed_orcids":["https://orcid.org/0000-0003-0237-1107"]},"institutions":[{"id":"https://openalex.org/I4210113613","display_name":"Fifth Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/01wfgh551","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210113613"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bing Wang","raw_affiliation_strings":["Department of Vascular Surgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Vascular Surgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, People's Republic of China","institution_ids":["https://openalex.org/I4210113613"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5074728970","https://openalex.org/A5100382537"],"corresponding_institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210113613"],"apc_list":null,"apc_paid":null,"fwci":1.4177,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.7904809,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"11","issue":"45","first_page":"10883","last_page":"10895"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ph-sensitive-hydrogels","display_name":"pH-responsive hydrogels","score":0.9079999923706055},{"id":"https://openalex.org/keywords/supramolecular-hydrogels","display_name":"supramolecular hydrogels","score":0.9850000143051147},{"id":"https://openalex.org/keywords/catalase-like-activity","display_name":"catalase-like activity","score":0.5879999995231628},{"id":"https://openalex.org/keywords/photothermal-therapy","display_name":"photothermal therapy","score":0.9359999895095825},{"id":"https://openalex.org/keywords/photodynamic-therapy","display_name":"photodynamic therapy","score":1.0},{"id":"https://openalex.org/keywords/chemodynamic-therapy","display_name":"chemodynamic therapy","score":0.9929999709129333},{"id":"https://openalex.org/keywords/synergistic-cancer-therapy","display_name":"synergistic cancer therapy","score":0.7360000014305115},{"id":"https://openalex.org/keywords/tumor-growth-inhibition","display_name":"tumor growth inhibition","score":0.6740000247955322},{"id":"https://openalex.org/keywords/alpha-cyclodextrin","display_name":"\u03b1-cyclodextrin","score":0.7310000061988831},{"id":"https://openalex.org/keywords/cancer-cells","display_name":"cancer cells","score":0.3109999895095825}],"concepts":[{"id":"https://openalex.org/C182606246","wikidata":"https://www.wikidata.org/wiki/Q7187926","display_name":"Photothermal therapy","level":2,"score":0.9441317319869995},{"id":"https://openalex.org/C2781323092","wikidata":"https://www.wikidata.org/wiki/Q1428072","display_name":"Photodynamic therapy","level":2,"score":0.6353319883346558},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.6161119341850281},{"id":"https://openalex.org/C93275456","wikidata":"https://www.wikidata.org/wiki/Q756449","display_name":"Supramolecular chemistry","level":3,"score":0.6064360737800598},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5192506313323975},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.45076310634613037},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.28013303875923157},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.09847167134284973},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07949697971343994}],"mesh":[{"descriptor_ui":"D000082703","descriptor_name":"Photothermal Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000171","descriptor_name":"Acrolein","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008823","descriptor_name":"Micelles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1039/d3tb01769a","doi":"https://doi.org/10.1039/d3tb01769a","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d3tb01769a","pdf_url":null,"source":{"id":"https://openalex.org/S2479884170","display_name":"Journal of Materials Chemistry B","issn_l":"2050-750X","issn":["2050-750X","2050-7518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Chemistry B","raw_type":"journal-article"},{"id":"pmid:37917009","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37917009","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of materials chemistry. B","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4911491592","display_name":null,"funder_award_id":"82172040","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8227386290","display_name":null,"funder_award_id":"2022YFC3601703","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W2098627399","https://openalex.org/W2883440571","https://openalex.org/W2915245248","https://openalex.org/W2943443652","https://openalex.org/W2950810779","https://openalex.org/W2969171269","https://openalex.org/W2969354046","https://openalex.org/W2971750444","https://openalex.org/W2984247274","https://openalex.org/W2985055119","https://openalex.org/W2995423159","https://openalex.org/W2997115421","https://openalex.org/W3000458449","https://openalex.org/W3005227746","https://openalex.org/W3009454743","https://openalex.org/W3021263115","https://openalex.org/W3027592362","https://openalex.org/W3034976992","https://openalex.org/W3109885192","https://openalex.org/W3128646645","https://openalex.org/W3132806796","https://openalex.org/W3139116703","https://openalex.org/W3147142721","https://openalex.org/W3149139278","https://openalex.org/W3154736103","https://openalex.org/W3165197650","https://openalex.org/W3167689071","https://openalex.org/W3190743115","https://openalex.org/W3209581105","https://openalex.org/W3213712820","https://openalex.org/W3214416664","https://openalex.org/W4200484393","https://openalex.org/W4205552366","https://openalex.org/W4205769552","https://openalex.org/W4206495089","https://openalex.org/W4210766679","https://openalex.org/W4213038867","https://openalex.org/W4214514443","https://openalex.org/W4221034065","https://openalex.org/W4226401713","https://openalex.org/W4280607680","https://openalex.org/W4281390873","https://openalex.org/W4289866450","https://openalex.org/W4293056873","https://openalex.org/W4294564773","https://openalex.org/W4307336173","https://openalex.org/W4308440262","https://openalex.org/W4310022485","https://openalex.org/W4313531291","https://openalex.org/W4316114550","https://openalex.org/W4362513903"],"related_works":["https://openalex.org/W4414511413","https://openalex.org/W2805896798","https://openalex.org/W4311192799","https://openalex.org/W3046197869","https://openalex.org/W2987834018","https://openalex.org/W4399025693","https://openalex.org/W4388209330","https://openalex.org/W3131258113","https://openalex.org/W2892226596","https://openalex.org/W7161589481"],"abstract_inverted_index":{"experiments":[0],"that":[1],"the":[2,18,23],"PCMS@PAC/\u03b1-CD":[3],"Gel":[4],"was":[5],"highly":[6],"cytotoxic":[7],"to":[8],"cancer":[9],"cells":[10],"and":[11,27],"could":[12],"effectively":[13],"inhibit":[14],"tumor":[15],"growth,":[16],"indicating":[17],"potential":[19],"for":[20],"applications":[21],"in":[22],"fields":[24],"of":[25],"biomedicine":[26],"smart":[28],"materials.":[29]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-10-25T00:00:00"}