{"id":"https://openalex.org/W4387912648","doi":"https://doi.org/10.34084/bshr.1357005","title":"Myocardial Protection With Remote Ischemic Preconditioning In Congenital Heart Surgery: Does It Deliver What Is Expected?","display_name":"Myocardial Protection With Remote Ischemic Preconditioning In Congenital Heart Surgery: Does It Deliver What Is Expected?","publication_year":2023,"publication_date":"2023-10-24","ids":{"openalex":"https://openalex.org/W4387912648","doi":"https://doi.org/10.34084/bshr.1357005"},"language":"en","primary_location":{"id":"doi:10.34084/bshr.1357005","doi":"https://doi.org/10.34084/bshr.1357005","is_oa":true,"landing_page_url":"https://doi.org/10.34084/bshr.1357005","pdf_url":"https://dergipark.org.tr/en/download/article-file/3393314","source":{"id":"https://openalex.org/S4210223973","display_name":"JOURNAL OF BIOTECHNOLOGY AND STRATEGIC HEALTH RESEARCH","issn_l":"2587-1641","issn":["2587-1641"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biotechnology and Strategic Health Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://dergipark.org.tr/en/download/article-file/3393314","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054312787","display_name":"Ak\u0131n Arslan","orcid":"https://orcid.org/0000-0003-1380-6102","observed_orcids":["https://orcid.org/0000-0003-1380-6102"]},"institutions":[{"id":"https://openalex.org/I103703290","display_name":"Sakarya University","ror":"https://ror.org/04ttnw109","country_code":"TR","type":"education","lineage":["https://openalex.org/I103703290"]},{"id":"https://openalex.org/I4210116985","display_name":"Sakarya E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/02h67ht97","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ak\u0131n ARSLAN","raw_affiliation_strings":["SAKARYA UN\u0130VERS\u0130TES\u0130 E\u011e\u0130T\u0130M VE ARA\u015e. HASTANES\u0130"],"raw_orcid":"https://orcid.org/0000-0003-1380-6102","affiliations":[{"raw_affiliation_string":"SAKARYA UN\u0130VERS\u0130TES\u0130 E\u011e\u0130T\u0130M VE ARA\u015e. HASTANES\u0130","institution_ids":["https://openalex.org/I103703290","https://openalex.org/I4210116985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029322263","display_name":"Emir Cant\u00fcrk","orcid":"https://orcid.org/0000-0003-1485-0009","observed_orcids":["https://orcid.org/0000-0003-1485-0009"]},"institutions":[{"id":"https://openalex.org/I3125470973","display_name":"Istanbul Medipol University","ror":"https://ror.org/037jwzz50","country_code":"TR","type":"education","lineage":["https://openalex.org/I3125470973"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Emir CANT\u00dcRK","raw_affiliation_strings":["\u0130STANBUL MED\u0130POL \u00dcN\u0130VERS\u0130TES\u0130"],"raw_orcid":"https://orcid.org/0000-0003-1485-0009","affiliations":[{"raw_affiliation_string":"\u0130STANBUL MED\u0130POL \u00dcN\u0130VERS\u0130TES\u0130","institution_ids":["https://openalex.org/I3125470973"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078001296","display_name":"Turgut Aksoy","orcid":"https://orcid.org/0000-0001-5041-0364","observed_orcids":["https://orcid.org/0000-0001-5041-0364"]},"institutions":[{"id":"https://openalex.org/I4210121333","display_name":"Istinye University","ror":"https://ror.org/03081nz23","country_code":"TR","type":"education","lineage":["https://openalex.org/I4210121333"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Turgut AKSOY","raw_affiliation_strings":["\u0130ST\u0130NYE \u00dcN\u0130VERS\u0130TES\u0130, TIP FAK\u00dcLTES\u0130"],"raw_orcid":"https://orcid.org/0000-0001-5041-0364","affiliations":[{"raw_affiliation_string":"\u0130ST\u0130NYE \u00dcN\u0130VERS\u0130TES\u0130, TIP FAK\u00dcLTES\u0130","institution_ids":["https://openalex.org/I4210121333"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"3","first_page":"192","last_page":"200"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.027400000020861626,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/remote-ischemic-preconditioning","display_name":"remote ischemic preconditioning","score":0.9990000128746033},{"id":"https://openalex.org/keywords/congenital-heart-surgery","display_name":"congenital heart surgery","score":0.8410000205039978},{"id":"https://openalex.org/keywords/cardioprotection","display_name":"cardioprotection","score":0.9520000219345093},{"id":"https://openalex.org/keywords/ischemia-reperfusion-injury","display_name":"ischemia-reperfusion injury","score":0.9649999737739563},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.8489999771118164},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":1.0},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7559999823570251},{"id":"https://openalex.org/keywords/antioxidant-markers","display_name":"antioxidant biomarkers","score":0.7070000171661377},{"id":"https://openalex.org/keywords/in-hospital-mortality","display_name":"in-hospital mortality","score":0.6830000281333923},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.9829999804496765}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9068853855133057},{"id":"https://openalex.org/C2779311647","wikidata":"https://www.wikidata.org/wiki/Q17148404","display_name":"Ischemic preconditioning","level":3,"score":0.7844079732894897},{"id":"https://openalex.org/C2778789114","wikidata":"https://www.wikidata.org/wiki/Q235007","display_name":"Cardiac surgery","level":2,"score":0.6967695355415344},{"id":"https://openalex.org/C2778401633","wikidata":"https://www.wikidata.org/wiki/Q418661","display_name":"Malondialdehyde","level":3,"score":0.6704542636871338},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5086618065834045},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.506388783454895},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.5031759142875671},{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.4335050582885742},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.39945995807647705},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3860853314399719},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.350990355014801},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.3047322630882263},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.06342503428459167},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.34084/bshr.1357005","doi":"https://doi.org/10.34084/bshr.1357005","is_oa":true,"landing_page_url":"https://doi.org/10.34084/bshr.1357005","pdf_url":"https://dergipark.org.tr/en/download/article-file/3393314","source":{"id":"https://openalex.org/S4210223973","display_name":"JOURNAL OF BIOTECHNOLOGY AND STRATEGIC HEALTH RESEARCH","issn_l":"2587-1641","issn":["2587-1641"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biotechnology and Strategic Health Research","raw_type":"journal-article"},{"id":"pmh:oai:dergipark.org.tr:article/1357005","doi":null,"is_oa":true,"landing_page_url":"https://dergipark.org.tr/tr/pub/bshr/issue/80703/1357005","pdf_url":"https://dergipark.org.tr/tr/download/article-file/3393314","source":{"id":"https://openalex.org/S4306401840","display_name":"DergiPark (Istanbul University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67581229","host_organization_name":"Istanbul University","host_organization_lineage":["https://openalex.org/I67581229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Biotechnology and Strategic Health Research","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.34084/bshr.1357005","doi":"https://doi.org/10.34084/bshr.1357005","is_oa":true,"landing_page_url":"https://doi.org/10.34084/bshr.1357005","pdf_url":"https://dergipark.org.tr/en/download/article-file/3393314","source":{"id":"https://openalex.org/S4210223973","display_name":"JOURNAL OF BIOTECHNOLOGY AND STRATEGIC HEALTH RESEARCH","issn_l":"2587-1641","issn":["2587-1641"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biotechnology and Strategic Health Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387912648.pdf","grobid_xml":"https://content.openalex.org/works/W4387912648.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W204358047","https://openalex.org/W1970382485","https://openalex.org/W1975109243","https://openalex.org/W1995675938","https://openalex.org/W2002926363","https://openalex.org/W2017199287","https://openalex.org/W2031819880","https://openalex.org/W2037434205","https://openalex.org/W2057522312","https://openalex.org/W2086304683","https://openalex.org/W2089335936","https://openalex.org/W2103900156","https://openalex.org/W2118705596","https://openalex.org/W2139131794","https://openalex.org/W2141900287","https://openalex.org/W2144475885","https://openalex.org/W2146217294","https://openalex.org/W2151639536","https://openalex.org/W2369162156","https://openalex.org/W2396573404","https://openalex.org/W2472293049","https://openalex.org/W2903997049"],"related_works":["https://openalex.org/W125028120","https://openalex.org/W7005540974","https://openalex.org/W2108306393","https://openalex.org/W113658129","https://openalex.org/W3005275958","https://openalex.org/W4246030300","https://openalex.org/W1005459190","https://openalex.org/W2317460655","https://openalex.org/W2770492096","https://openalex.org/W1969440085"],"abstract_inverted_index":{"Objective:":[0],"The":[1,20,52,98,125,182],"discovery":[2],"of":[3,7,22,45,63,71,172,184,234],"the":[4,42,168,214,232],"protective":[5],"effects":[6,183],"antioxidant":[8],"agents":[9],"on":[10,27,48,187,231],"organ":[11],"functions":[12],"enabled":[13],"this":[14],"system":[15],"to":[16,60,84],"be":[17],"tested":[18],"artificially.":[19],"impact":[21],"remote":[23],"ischemic":[24,46,185],"preconditioning":[25,47,186],"(RIPC)":[26,68,113],"surgical":[28,100],"clinical":[29],"outcomes":[30],"in":[31,65,73,94,110,121,137,147,153,170,196,223,225],"patients":[32,64],"with":[33],"congenital":[34,197],"heart":[35],"defects":[36],"is":[37,219,237],"unclear.":[38],"This":[39],"study":[40,53],"investigated":[41],"early":[43],"consequences":[44],"cardiac":[49,89,188,198],"protection.":[50],"Methods:":[51],"was":[54,103,130,152,158,163],"designed":[55],"prospectively.":[56],"Cuffs":[57],"were":[58,92],"applied":[59],"one":[61],"leg":[62],"Group":[66,111,122],"1":[67,112,139],"after":[69],"induction":[70],"anesthesia":[72],"three":[74],"cycles":[75],"(5":[76],"min":[77,82],"inflation":[78],"followed":[79],"by":[80],"5":[81],"reperfusion)":[83],"precondition":[85],"ischemia-reperfusion.":[86],"Antioxidant":[87],"and":[88,114,140,176,205],"marker":[90],"levels":[91,179],"recorded":[93],"blood":[95],"samples.":[96],"Results:":[97],"patients'":[99,126],"median":[101,127],"age":[102],"19.1":[104],"months":[105,116,132,142],"(IQR=":[106,117,133,143],"3.7-":[107],"57.7":[108],"months)":[109,120,136,146],"16.7":[115],"7.8-":[118],"35.9":[119],"2":[123],"(Control).":[124],"follow-up":[128],"period":[129],"58.3":[131],"54.3-":[134],"62.1":[135],"group":[138,148],"37.1":[141],"34.8-":[144],"41.7":[145],"2.":[149],"Hospital":[150],"mortality":[151,224],"7":[154],"(10.4%)":[155],"patients.":[156],"There":[157,162],"no":[159,220],"late":[160],"mortality.":[161],"a":[164,228],"significant":[165,221],"difference":[166,222],"between":[167],"groups":[169],"terms":[171],"Superoxide":[173],"Dismutase":[174],"(SOD)":[175],"Malondialdehyde":[177],"(MDA)":[178],"(p<005).":[180],"Conclusion:":[181],"protection":[189],"have":[190],"not":[191],"been":[192],"proven":[193],"yet.":[194],"Especially":[195],"patients,":[199,227],"chronic":[200],"stimuli":[201],"such":[202],"as":[203],"hypoxia":[204],"cyanosis":[206],"or":[207],"drugs":[208],"used":[209],"before":[210],"surgery":[211],"may":[212],"affect":[213],"study\u2019s":[215],"results.":[216],"Although":[217],"there":[218],"these":[226],"positive":[229],"effect":[230],"length":[233],"hospital":[235],"stay":[236],"promising.":[238]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2023-10-25T00:00:00"}