{"id":"https://openalex.org/W4387907654","doi":"https://doi.org/10.12681/jhvms.30666","title":"Establishment of AA-NAT, SCD, PROP1, and IGFBP3 gene frequency distributions in Karacabey Merino and Kivircik Sheep Breeds","display_name":"Establishment of AA-NAT, SCD, PROP1, and IGFBP3 gene frequency distributions in Karacabey Merino and Kivircik Sheep Breeds","publication_year":2023,"publication_date":"2023-10-18","ids":{"openalex":"https://openalex.org/W4387907654","doi":"https://doi.org/10.12681/jhvms.30666"},"language":"en","primary_location":{"id":"doi:10.12681/jhvms.30666","doi":"https://doi.org/10.12681/jhvms.30666","is_oa":true,"landing_page_url":"https://doi.org/10.12681/jhvms.30666","pdf_url":"https://ejournals.epublishing.ekt.gr/index.php/jhvms/article/download/30666/26742","source":{"id":"https://openalex.org/S2475387103","display_name":"Journal of the Hellenic Veterinary Medical Society","issn_l":"1792-2720","issn":["1792-2720","2585-3724"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318077","host_organization_name":"National Documentation Centre","host_organization_lineage":["https://openalex.org/P4310318077"],"host_organization_lineage_names":["National Documentation Centre"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Hellenic Veterinary Medical Society","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://ejournals.epublishing.ekt.gr/index.php/jhvms/article/download/30666/26742","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021799526","display_name":"Deniz Din\u00e7el","orcid":"https://orcid.org/0000-0002-8015-9032","observed_orcids":["https://orcid.org/0000-0002-8015-9032"]},"institutions":[{"id":"https://openalex.org/I131835042","display_name":"Bursa Uluda\u011f \u00dcni\u0307versi\u0307tesi\u0307","ror":"https://ror.org/03tg3eb07","country_code":"TR","type":"education","lineage":["https://openalex.org/I131835042"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"D Din\u00e7el","raw_affiliation_strings":["Department of Genetics, Bursa Uludag University, Faculty of Veterinary Medicine, Bursa - T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Bursa Uludag University, Faculty of Veterinary Medicine, Bursa - T\u00fcrkiye","institution_ids":["https://openalex.org/I131835042"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5116752885","display_name":"\u00d6zden \u00c7obano\u011flu","orcid":"https://orcid.org/0000-0001-9633-634X","observed_orcids":["https://orcid.org/0000-0001-9633-634X","https://orcid.org/0000-0002-8247-9347"]},"institutions":[{"id":"https://openalex.org/I131835042","display_name":"Bursa Uluda\u011f \u00dcni\u0307versi\u0307tesi\u0307","ror":"https://ror.org/03tg3eb07","country_code":"TR","type":"education","lineage":["https://openalex.org/I131835042"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"\u00d6 \u00c7obano\u011flu","raw_affiliation_strings":["Department of Genetics, Bursa Uludag University, Faculty of Veterinary Medicine, Bursa - T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Bursa Uludag University, Faculty of Veterinary Medicine, Bursa - T\u00fcrkiye","institution_ids":["https://openalex.org/I131835042"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I131835042"],"apc_list":null,"apc_paid":null,"fwci":0.3322,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.56763023,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"74","issue":"3","first_page":"6003","last_page":"6012"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/scd-gene","display_name":"SCD gene","score":0.9679999947547913},{"id":"https://openalex.org/keywords/prop1-gene","display_name":"PROP1 gene","score":0.9919999837875366},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9319999814033508},{"id":"https://openalex.org/keywords/kivircik-sheep","display_name":"Kivircik sheep","score":0.9980000257492065},{"id":"https://openalex.org/keywords/genotype-distribution","display_name":"genotype distribution","score":0.6990000009536743},{"id":"https://openalex.org/keywords/hardy-weinberg-equilibrium","display_name":"Hardy-Weinberg equilibrium","score":0.9020000100135803},{"id":"https://openalex.org/keywords/polymorphic-information-content","display_name":"polymorphism information content","score":0.7860000133514404},{"id":"https://openalex.org/keywords/monomorphism","display_name":"monomorphism","score":0.48899999260902405}],"concepts":[{"id":"https://openalex.org/C2778279177","wikidata":"https://www.wikidata.org/wiki/Q18027678","display_name":"IGFBP3","level":4,"score":0.6911200284957886},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.6806174516677856},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6336356401443481},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.5378581285476685},{"id":"https://openalex.org/C76252995","wikidata":"https://www.wikidata.org/wiki/Q3395645","display_name":"Gene polymorphism","level":4,"score":0.5236408710479736},{"id":"https://openalex.org/C37463918","wikidata":"https://www.wikidata.org/wiki/Q387981","display_name":"Allele frequency","level":4,"score":0.5215963125228882},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.5172677636146545},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5162025094032288},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5069325566291809},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4797010123729706},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.4724358022212982},{"id":"https://openalex.org/C175239580","wikidata":"https://www.wikidata.org/wiki/Q656595","display_name":"Genotype frequency","level":5,"score":0.4678407907485962},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0835149884223938},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.12681/jhvms.30666","doi":"https://doi.org/10.12681/jhvms.30666","is_oa":true,"landing_page_url":"https://doi.org/10.12681/jhvms.30666","pdf_url":"https://ejournals.epublishing.ekt.gr/index.php/jhvms/article/download/30666/26742","source":{"id":"https://openalex.org/S2475387103","display_name":"Journal of the Hellenic Veterinary Medical Society","issn_l":"1792-2720","issn":["1792-2720","2585-3724"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318077","host_organization_name":"National Documentation Centre","host_organization_lineage":["https://openalex.org/P4310318077"],"host_organization_lineage_names":["National Documentation Centre"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Hellenic Veterinary Medical Society","raw_type":"journal-article"},{"id":"pmh:7d114eca-7c1d-4279-8164-13293f19ec2c","doi":null,"is_oa":true,"landing_page_url":"https://avesis.uludag.edu.tr/publication/details/7d114eca-7c1d-4279-8164-13293f19ec2c/oai","pdf_url":"https://avesis.uludag.edu.tr/publication/details/7d114eca-7c1d-4279-8164-13293f19ec2c/oai/document.pdf","source":{"id":"https://openalex.org/S7407055210","display_name":"Bursa Uludag University - AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.12681/jhvms.30666","doi":"https://doi.org/10.12681/jhvms.30666","is_oa":true,"landing_page_url":"https://doi.org/10.12681/jhvms.30666","pdf_url":"https://ejournals.epublishing.ekt.gr/index.php/jhvms/article/download/30666/26742","source":{"id":"https://openalex.org/S2475387103","display_name":"Journal of the Hellenic Veterinary Medical Society","issn_l":"1792-2720","issn":["1792-2720","2585-3724"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318077","host_organization_name":"National Documentation Centre","host_organization_lineage":["https://openalex.org/P4310318077"],"host_organization_lineage_names":["National Documentation Centre"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Hellenic Veterinary Medical Society","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6735000014305115,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387907654.pdf","grobid_xml":"https://content.openalex.org/works/W4387907654.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W576407751","https://openalex.org/W773037186","https://openalex.org/W1803375514","https://openalex.org/W1878535762","https://openalex.org/W1978535815","https://openalex.org/W1979487925","https://openalex.org/W1980207645","https://openalex.org/W1981765570","https://openalex.org/W1999829654","https://openalex.org/W2004926582","https://openalex.org/W2006611752","https://openalex.org/W2015215627","https://openalex.org/W2023076009","https://openalex.org/W2044465850","https://openalex.org/W2058743434","https://openalex.org/W2061535314","https://openalex.org/W2065790890","https://openalex.org/W2077217538","https://openalex.org/W2089009272","https://openalex.org/W2116843629","https://openalex.org/W2117821650","https://openalex.org/W2127107334","https://openalex.org/W2132960882","https://openalex.org/W2149867015","https://openalex.org/W2156436519","https://openalex.org/W2184009633","https://openalex.org/W2188048203","https://openalex.org/W2259259761","https://openalex.org/W2315619111","https://openalex.org/W2329245547","https://openalex.org/W2468842317","https://openalex.org/W2897456196","https://openalex.org/W2902008555","https://openalex.org/W2905092709","https://openalex.org/W2975560884","https://openalex.org/W3197640057","https://openalex.org/W3210382448","https://openalex.org/W4246952978","https://openalex.org/W6776737641","https://openalex.org/W7020946556"],"related_works":["https://openalex.org/W1989305569","https://openalex.org/W2347157021","https://openalex.org/W2360984943","https://openalex.org/W1023990884","https://openalex.org/W3154085847","https://openalex.org/W1506895856","https://openalex.org/W2390776711","https://openalex.org/W3118372692","https://openalex.org/W2351211655","https://openalex.org/W7132562724"],"abstract_inverted_index":{"Thus,":[0],"the":[1,4,10,21,25,34,62,65,89,100,162,167,171,180,194],"aim":[2],"of":[3,13,45,64,161,170,196,209],"current":[5],"study":[6],"was":[7,28,58,106,111],"to":[8,60],"investigate":[9],"genotypic":[11],"dispersion":[12],"AA-NAT,":[14],"SCD,":[15],"PROP1,":[16],"and":[17,52,72,80,88,115,128,135,140,144,151,204],"IGFBP3":[18,163,172],"genes":[19,198,211],"in":[20,99,118,149,159,179,202,207],"target":[22],"population.":[23,101],"Primarily,":[24],"genomic":[26,38],"DNA":[27],"isolated":[29],"from":[30,68,109],"blood":[31],"samples":[32],"by":[33],"phenol/chloroform":[35],"method.":[36],"The":[37,55,120],"analyses":[39],"were":[40,94,124,156,175],"performed":[41],"on":[42,199],"a":[43,103],"total":[44],"160":[46],"Karacabey":[47],"Merino":[48],"(KM)":[49],"sheep":[50,206],"(n=80)":[51],"Kivircik":[53,152,205],"(n=80).":[54],"PCR-RFLP":[56],"method":[57],"used":[59],"determine":[61],"genotype":[63,142],"SNPs.":[66],"Deviation":[67],"Hardy\u2013Weinberg":[69],"equilibrium":[70],"(HWE)":[71],"population":[73],"genetic":[74],"assays":[75],"such":[76],"as":[77,177],"observed":[78],"(Ho)":[79],"expected":[81],"(He)":[82],"heterozygosities,":[83],"effective":[84],"allele":[85],"numbers":[86],"(Ne),":[87],"polymorphism":[90],"information":[91],"content":[92],"(PIC)":[93],"calculated":[95],"for":[96,130,137,146,192],"each":[97],"gene":[98,117,139,148,173],"As":[102],"result,":[104],"there":[105],"no":[107],"deviation":[108],"HWE":[110],"determined":[112,176],"except":[113],"SCD":[114,138],"PROP1":[116,147],"KM.":[119],"most":[121],"frequent":[122],"genotypes":[123],"found":[125],"AA":[126],"(66,25%":[127],"87,50%)":[129],"AA-NAT":[131],"gene,":[132],"CC":[133,141],"(93,75%":[134],"91,25%)":[136],"(70,00%":[143],"56,25%)":[145],"KM":[150,203],"sheep.":[153],"All":[154],"breeds":[155],"detected":[157],"monomorphic":[158,178],"terms":[160,208],"gene.":[164],"In":[165],"conclusion,":[166],"other":[168],"regions":[169],"which":[174],"studied":[181],"flock":[182],"could":[183],"be":[184,190],"researched.":[185],"Moreover,":[186],"further":[187],"studies":[188],"should":[189],"necessary":[191],"defining":[193],"effects":[195],"investigated":[197],"related":[200],"traits":[201],"polymorphic":[210],"specified.":[212]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2023-10-25T00:00:00"}