{"id":"https://openalex.org/W4387865663","doi":"https://doi.org/10.1007/s10072-023-07140-w","title":"Heterogenous electrophysiological features in early stage of hereditary transthyretin amyloidosis neuropathy","display_name":"Heterogenous electrophysiological features in early stage of hereditary transthyretin amyloidosis neuropathy","publication_year":2023,"publication_date":"2023-10-23","ids":{"openalex":"https://openalex.org/W4387865663","doi":"https://doi.org/10.1007/s10072-023-07140-w","pmid":"https://pubmed.ncbi.nlm.nih.gov/37870643","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10942904"},"language":"en","primary_location":{"id":"doi:10.1007/s10072-023-07140-w","doi":"https://doi.org/10.1007/s10072-023-07140-w","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10072-023-07140-w","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10072-023-07140-w.pdf","source":{"id":"https://openalex.org/S75480959","display_name":"Neurological Sciences","issn_l":"1590-1874","issn":["1590-1874","1590-3478"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurological Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s10072-023-07140-w.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004115361","display_name":"Stefano Tozza","orcid":"https://orcid.org/0000-0002-9672-4577","observed_orcids":["https://orcid.org/0000-0002-9672-4577"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Stefano Tozza","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy. stefano.tozza@unina.it","Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":"https://orcid.org/0000-0002-9672-4577","affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy. stefano.tozza@unina.it","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055926856","display_name":"Giovanni Palumbo","orcid":"https://orcid.org/0000-0003-3757-4967","observed_orcids":["https://orcid.org/0000-0003-3757-4967"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanni Palumbo","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085857415","display_name":"Daniele Severi","orcid":"https://orcid.org/0000-0003-3131-032X","observed_orcids":["https://orcid.org/0000-0003-3131-032X"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Daniele Severi","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066041497","display_name":"Aniello Iovino","orcid":"https://orcid.org/0000-0002-9863-9958","observed_orcids":["https://orcid.org/0000-0002-9863-9958"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Aniello Iovino","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061891720","display_name":"Emanuele Spina","orcid":"https://orcid.org/0000-0001-5123-2459","observed_orcids":["https://orcid.org/0000-0001-5123-2459"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Emanuele Spina","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014462542","display_name":"Francesco Aruta","orcid":"https://orcid.org/0000-0002-8197-3845","observed_orcids":["https://orcid.org/0000-0002-8197-3845"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesco Aruta","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009516005","display_name":"Emanuele Cassano","orcid":"https://orcid.org/0000-0002-0728-2640","observed_orcids":["https://orcid.org/0000-0002-0728-2640"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Emanuele Cassano","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082938183","display_name":"Rosa Iodice","orcid":"https://orcid.org/0000-0002-6939-4760","observed_orcids":["https://orcid.org/0000-0002-6939-4760"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rosa Iodice","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075900771","display_name":"Raffaele Dubbioso","orcid":"https://orcid.org/0000-0003-2487-4741","observed_orcids":["https://orcid.org/0000-0003-2487-4741"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Raffaele Dubbioso","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015796471","display_name":"Lucia Ruggiero","orcid":"https://orcid.org/0000-0002-7756-9567","observed_orcids":["https://orcid.org/0000-0002-7756-9567"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lucia Ruggiero","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031566256","display_name":"Maria Nolano","orcid":"https://orcid.org/0000-0002-4849-1318","observed_orcids":["https://orcid.org/0000-0002-4849-1318"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Nolano","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061007916","display_name":"Lucio Santoro","orcid":"https://orcid.org/0000-0001-9507-2303","observed_orcids":["https://orcid.org/0000-0001-9507-2303","https://orcid.org/0009-0005-8140-3032"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lucio Santoro","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062782724","display_name":"Fiore Manganelli","orcid":"https://orcid.org/0000-0002-1442-9604","observed_orcids":["https://orcid.org/0000-0002-1442-9604","https://orcid.org/0000-0001-9478-3744"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fiore Manganelli","raw_affiliation_strings":["Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples \"Federico II\", Via Sergio Pansini, 5, 80131, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5004115361"],"corresponding_institution_ids":["https://openalex.org/I71267560"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":{"value":3690,"currency":"USD","value_usd":3690},"fwci":0.7059,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.73442672,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"45","issue":"4","first_page":"1685","last_page":"1689"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12331","display_name":"Hereditary Neurological Disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11735","display_name":"Peripheral Neuropathies and Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/familial-amyloid-polyneuropathy","display_name":"hereditary transthyretin amyloidosis","score":0.968999981880188},{"id":"https://openalex.org/keywords/variant-transthyretin","display_name":"variant transthyretin","score":0.8399999737739563},{"id":"https://openalex.org/keywords/peripheral-neuropathy","display_name":"peripheral neuropathy","score":0.7699999809265137},{"id":"https://openalex.org/keywords/nerve-conduction-studies","display_name":"nerve conduction studies","score":0.8420000076293945},{"id":"https://openalex.org/keywords/early-diagnosis","display_name":"early diagnosis","score":0.8299999833106995},{"id":"https://openalex.org/keywords/axonal-polyneuropathy","display_name":"axonal neuropathy","score":0.9319999814033508},{"id":"https://openalex.org/keywords/sensorimotor-neuropathy","display_name":"sensorimotor neuropathy","score":0.9459999799728394},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.5149999856948853},{"id":"https://openalex.org/keywords/ttr-gene-mutations","display_name":"TTR gene mutations","score":0.5600000023841858}],"concepts":[{"id":"https://openalex.org/C121157162","wikidata":"https://www.wikidata.org/wiki/Q419999","display_name":"Transthyretin","level":2,"score":0.7109993696212769},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6923113465309143},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.6372684836387634},{"id":"https://openalex.org/C2779951007","wikidata":"https://www.wikidata.org/wiki/Q816798","display_name":"Amyloidosis","level":2,"score":0.6074298620223999},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.5866097807884216},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5315282940864563},{"id":"https://openalex.org/C2777767895","wikidata":"https://www.wikidata.org/wiki/Q4691924","display_name":"Age of onset","level":3,"score":0.472903847694397},{"id":"https://openalex.org/C179253579","wikidata":"https://www.wikidata.org/wiki/Q6276958","display_name":"Nerve conduction velocity","level":2,"score":0.45395606756210327},{"id":"https://openalex.org/C2779889316","wikidata":"https://www.wikidata.org/wiki/Q642836","display_name":"Neuroradiology","level":3,"score":0.4512266218662262},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4402558505535126},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4174264073371887},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3226674795150757},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000339","descriptor_name":"Affect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009431","descriptor_name":"Neural Conduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011228","descriptor_name":"Prealbumin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D028227","descriptor_name":"Amyloid Neuropathies, Familial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D028227","descriptor_name":"Amyloid Neuropathies, Familial","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D028227","descriptor_name":"Amyloid Neuropathies, Familial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s10072-023-07140-w","doi":"https://doi.org/10.1007/s10072-023-07140-w","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10072-023-07140-w","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10072-023-07140-w.pdf","source":{"id":"https://openalex.org/S75480959","display_name":"Neurological Sciences","issn_l":"1590-1874","issn":["1590-1874","1590-3478"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurological Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10942904","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10942904","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10942904/pdf/10072_2023_Article_7140.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurol Sci","raw_type":"Text"},{"id":"pmid:37870643","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37870643","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1007/s10072-023-07140-w","doi":"https://doi.org/10.1007/s10072-023-07140-w","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10072-023-07140-w","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10072-023-07140-w.pdf","source":{"id":"https://openalex.org/S75480959","display_name":"Neurological Sciences","issn_l":"1590-1874","issn":["1590-1874","1590-3478"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurological Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320309590","display_name":"Universit\u00e0 degli Studi di Napoli Federico II","ror":"https://ror.org/05290cv24"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387865663.pdf","grobid_xml":"https://content.openalex.org/works/W4387865663.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1973953525","https://openalex.org/W2006368150","https://openalex.org/W2073849744","https://openalex.org/W2080914865","https://openalex.org/W2131271349","https://openalex.org/W2165547714","https://openalex.org/W2587394469","https://openalex.org/W2897818380","https://openalex.org/W2913289752","https://openalex.org/W3087792494","https://openalex.org/W3095724116","https://openalex.org/W3100534950","https://openalex.org/W3158356432","https://openalex.org/W3164824044","https://openalex.org/W3174865340","https://openalex.org/W4220752763","https://openalex.org/W4221031684","https://openalex.org/W4221122885","https://openalex.org/W4280544104","https://openalex.org/W4385555979"],"related_works":["https://openalex.org/W3158356432","https://openalex.org/W7122739079","https://openalex.org/W1899949139","https://openalex.org/W3117654493","https://openalex.org/W7130511333","https://openalex.org/W4220984999","https://openalex.org/W4414906993","https://openalex.org/W4392843384","https://openalex.org/W4387764481","https://openalex.org/W7126817204"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Hereditary":[1],"transthyretin-mediated":[2],"amyloidosis":[3],"(ATTRv,":[4],"v":[5],"for":[6,67],"variant)":[7],"is":[8],"a":[9,222],"progressive":[10],"disease":[11,122,145,201],"caused":[12],"by":[13,128],"mutations":[14],"in":[15,187,189,197,221],"the":[16,42,50,53,74,84,107,113,158,163,171,229,236,244],"TTR":[17,46],"gene,":[18],"leading":[19],"to":[20,40,59,105],"sensory-motor,":[21],"axonal":[22],"and":[23,81,95,115,124,151,176,225],"length-dependent":[24],"neuropathy.":[25],"However,":[26],"some":[27],"patients":[28,134,188,196],"may":[29,216],"show":[30],"variable":[31,203,223],"electrophysiological":[32,43,76,180,204,248],"pattern.":[33,178],"The":[34],"aim":[35],"of":[36,45,52,78,92,98,109,118,167,173,182,192,200,206,231,238,246],"this":[37],"study":[38,57],"was":[39,103,185],"evaluate":[41,106],"features":[44,65,111,166],"amyloid":[47],"neuropathy":[48,85,110,169,215],"at":[49,218,243],"time":[51,245],"first":[54,75,219,247],"nerve":[55,88],"conduction":[56,89],"(NCS)":[58],"assess":[60],"whether":[61],"there":[62],"were":[63],"distinguishing":[64],"useful":[66],"early":[68,114,198],"diagnosis.":[69],"METHODS:":[70],"We":[71,131],"retrospectively":[72],"revised":[73],"findings":[77,211],"ATTRv":[79,168,195,214,239],"patients,":[80],"we":[82],"categorized":[83],"based":[86,120],"on":[87,121],"slowing,":[90],"type":[91],"involved":[93],"fibres":[94],"distribution":[96],"pattern":[97,181,205],"PNS":[99,183,207],"involvement.":[100,208],"Cluster":[101],"analysis":[102,160],"performed":[104],"prevalence":[108],"between":[112],"late":[116,190],"stage":[117,191,199],"disease,":[119,193],"duration":[123,146],"disability":[125],"burden":[126],"assessed":[127],"NIS.":[129],"RESULTS:":[130],"recruited":[132],"33":[133],"(27":[135],"males)":[136],"with":[137],"mean":[138,144,152],"age":[139],"63.9":[140],"\u00b1":[141,148,155],"10.8":[142],"years,":[143],"2.8":[147],"2.4":[149],"years":[150],"NIS":[153],"47.6":[154],"41.8.":[156],"Overall,":[157],"frequency":[159],"showed":[161],"that":[162,213],"most":[164],"common":[165],"included":[170],"categories":[172],"axonal,":[174],"sensory-motor":[175],"neuronopathic-like":[177],"This":[179],"involvement":[184],"constant":[186],"whereas":[194],"displayed":[202],"DISCUSSION:":[209],"Our":[210],"demonstrated":[212],"present":[217],"NCS":[220],"way,":[224],"it":[226],"changes":[227],"over":[228],"course":[230],"disease.":[232],"Such":[233],"heterogeneity":[234],"makes":[235],"suspicion":[237],"even":[240],"more":[241],"challenging":[242],"examination.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-10-24T00:00:00"}