{"id":"https://openalex.org/W4387783232","doi":"https://doi.org/10.14309/01.ajg.0000966520.79061.ca","title":"S4220 Mixed Gastric Adenoneuroendocrine Carcinoma/Neuroendocrine Tumor in Crohn\u2019s Patient With Newly Diagnosed Hepatic Neuroendocrine Tumor","display_name":"S4220 Mixed Gastric Adenoneuroendocrine Carcinoma/Neuroendocrine Tumor in Crohn\u2019s Patient With Newly Diagnosed Hepatic Neuroendocrine Tumor","publication_year":2023,"publication_date":"2023-10-01","ids":{"openalex":"https://openalex.org/W4387783232","doi":"https://doi.org/10.14309/01.ajg.0000966520.79061.ca"},"language":"en","primary_location":{"id":"doi:10.14309/01.ajg.0000966520.79061.ca","doi":"https://doi.org/10.14309/01.ajg.0000966520.79061.ca","is_oa":false,"landing_page_url":"https://doi.org/10.14309/01.ajg.0000966520.79061.ca","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103927250","display_name":"Mohammad I. Bhatti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210152471","display_name":"Weill Cornell Medical College in Qatar","ror":"https://ror.org/05v5hg569","country_code":"QA","type":"education","lineage":["https://openalex.org/I4210152471"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["QA","US"],"is_corresponding":true,"raw_author_name":"Mohammad I. Bhatti","raw_affiliation_strings":["Weill Cornell Medicine-Qatar, Doha, Ad Dawhah, Qatar;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medicine-Qatar, Doha, Ad Dawhah, Qatar;","institution_ids":["https://openalex.org/I4210152471","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068930435","display_name":"Malik Mushannen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341523491","display_name":"NewYork\u2013Presbyterian Brooklyn Methodist Hospital","ror":"https://ror.org/04929s478","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700","https://openalex.org/I1341523491"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Malik Mushannen","raw_affiliation_strings":["New York Presbyterian-Brooklyn Methodist Hospital, Brooklyn, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York Presbyterian-Brooklyn Methodist Hospital, Brooklyn, NY;","institution_ids":["https://openalex.org/I1341523491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054641437","display_name":"Safah Khan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210152471","display_name":"Weill Cornell Medical College in Qatar","ror":"https://ror.org/05v5hg569","country_code":"QA","type":"education","lineage":["https://openalex.org/I4210152471"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["QA","US"],"is_corresponding":false,"raw_author_name":"Safah Khan","raw_affiliation_strings":["Weill Cornell Medicine-Qatar, Doha, Ad Dawhah, Qatar;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medicine-Qatar, Doha, Ad Dawhah, Qatar;","institution_ids":["https://openalex.org/I4210152471","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104441702","display_name":"Hamza Chaudhry","orcid":"https://orcid.org/0009-0003-3427-1108","observed_orcids":["https://orcid.org/0009-0003-3427-1108"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hamza Chaudhry","raw_affiliation_strings":["Weill Cornell Medical College, Friendswood, TX;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medical College, Friendswood, TX;","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078836906","display_name":"Lasha Gogokhia","orcid":"https://orcid.org/0000-0003-3652-0377","observed_orcids":["https://orcid.org/0000-0003-3652-0377"]},"institutions":[{"id":"https://openalex.org/I1340179700","display_name":"NewYork\u2013Presbyterian Hospital","ror":"https://ror.org/03gzbrs57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700"]},{"id":"https://openalex.org/I4405272987","display_name":"Weill Cornell Medical Center","ror":"https://ror.org/052v90092","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466","https://openalex.org/I4405272987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lasha Gogokhia","raw_affiliation_strings":["New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY;","institution_ids":["https://openalex.org/I1340179700","https://openalex.org/I4405272987"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047191452","display_name":"Dana J. Lukin","orcid":"https://orcid.org/0000-0003-4581-2267","observed_orcids":["https://orcid.org/0000-0003-4581-2267"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dana Lukin","raw_affiliation_strings":["Jill Roberts Center for Inflammatory Bowel Disease, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jill Roberts Center for Inflammatory Bowel Disease, New York, NY;","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059607973","display_name":"David W. Wan","orcid":"https://orcid.org/0000-0001-9361-8245","observed_orcids":["https://orcid.org/0000-0001-9361-8245"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Wan","raw_affiliation_strings":["Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5103927250"],"corresponding_institution_ids":["https://openalex.org/I4210152471","https://openalex.org/I4387153466"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"118","issue":"10S","first_page":"S2669","last_page":"S2669"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11485","display_name":"Gastrointestinal Tumor Research and Treatment","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mixed-neuroendocrine-non-neuroendocrine-neoplasm","display_name":"mixed neuroendocrine-non-neuroendocrine neoplasm","score":0.9490000009536743},{"id":"https://openalex.org/keywords/hepatic-neuroendocrine-tumor","display_name":"hepatic neuroendocrine tumor","score":0.8799999952316284},{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":0.8339999914169312},{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.6549999713897705},{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.5509999990463257},{"id":"https://openalex.org/keywords/liver-metastases","display_name":"liver metastasis","score":0.921999990940094},{"id":"https://openalex.org/keywords/protein-losing-enteropathy","display_name":"protein-losing enteropathy","score":0.8059999942779541},{"id":"https://openalex.org/keywords/melena","display_name":"melena","score":0.5270000100135803},{"id":"https://openalex.org/keywords/gastric-ulcer","display_name":"gastric ulcer","score":0.4449999928474426},{"id":"https://openalex.org/keywords/magnetic-resonance-enterography","display_name":"magnetic resonance enterography","score":0.5929999947547913},{"id":"https://openalex.org/keywords/cisplatin-etoposide-chemotherapy","display_name":"etoposide and cisplatin chemotherapy","score":0.949999988079071},{"id":"https://openalex.org/keywords/palliative-radiotherapy","display_name":"palliative radiotherapy","score":0.9089999794960022}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.960567831993103},{"id":"https://openalex.org/C2777424391","wikidata":"https://www.wikidata.org/wiki/Q1163908","display_name":"Melena","level":2,"score":0.5909783840179443},{"id":"https://openalex.org/C2779066768","wikidata":"https://www.wikidata.org/wiki/Q1981276","display_name":"Neuroendocrine tumors","level":2,"score":0.5633061528205872},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5218783020973206},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.48507800698280334},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.4721108675003052},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.4300293028354645},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3686997890472412},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.32543954253196716},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.1745869219303131}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.14309/01.ajg.0000966520.79061.ca","doi":"https://doi.org/10.14309/01.ajg.0000966520.79061.ca","is_oa":false,"landing_page_url":"https://doi.org/10.14309/01.ajg.0000966520.79061.ca","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Gastroenterology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4389495952","https://openalex.org/W4390889432","https://openalex.org/W2619611347","https://openalex.org/W2979648248","https://openalex.org/W4387763715","https://openalex.org/W4383314738","https://openalex.org/W4417251491","https://openalex.org/W3157535164","https://openalex.org/W4311505936","https://openalex.org/W4205208360"],"abstract_inverted_index":{"Introduction:":[0],"Mixed":[1,247],"neuroendocrine":[2,14,74,263],"non-neuroendocrine":[3,16,266],"neoplasm":[4,26],"(MiNENs)":[5],"are":[6,27,232],"a":[7,19,46,97,120,201,360,373],"rare":[8,234],"type":[9],"of":[10,24,45,96,130,140,153,168,179,198,240,256,261,272,299,368,380],"tumor":[11,75,171,220,311],"with":[12,48,51,58,70,111,144,172,195,316,321,359],"both":[13],"and":[15,31,65,102,222,264,348,351],"features":[17,23],"in":[18,37,185,219,235,293],"given":[20,189],"lesion.":[21],"The":[22],"this":[25,310],"not":[28],"well":[29],"defined":[30],"is":[32,35,332,354],"even":[33],"less":[34],"known":[36],"IBD":[38,300],"patients.":[39],"Here,":[40],"we":[41],"present":[42],"the":[43,81,107,127,131,141,166,175,180,262,265,281,303,369,381,387],"case":[44],"patient":[47,108,340],"Crohn\u2019s":[49,59],"disease":[50,60,337],"gastric":[52,85,123,142,170,181,274,306,384],"MiNEN.":[53],"Case":[54],"Description/Methods:":[55],"A":[56,88],"41-year-old-man":[57],"complicated":[61],"by":[62,205,251,259],"protein-losing":[63],"enteropathy":[64],"ileocolic":[66],"fistula":[67],"was":[68,92,183,193],"diagnosed":[69],"high":[71],"grade":[72],"hepatic":[73],"on":[76,126,362,386],"liver":[77,224],"biopsy.":[78],"MRE":[79,134],"at":[80,253],"time":[82],"also":[83,301],"showed":[84,119,135],"antrum":[86,143],"thickening.":[87],"month":[89],"later,":[90],"he":[91,353],"admitted":[93],"for":[94,187,238,305,309,327,336,356],"management":[95],"provoked":[98],"lower":[99],"extremity":[100],"DVT":[101],"bilateral":[103],"PE.":[104],"During":[105],"hospitalization,":[106],"developed":[109],"melena":[110],"acute":[112],"anemia":[113],"that":[114],"required":[115],"PRBC":[116],"transfusions.":[117],"EGD":[118,157],"large":[121,374,382],"clean-based":[122,383],"ulcer":[124,385],"found":[125],"greater":[128,388],"curvature":[129],"stomach.":[132],"Repeat":[133],"concentric":[136],"irregular":[137],"mural":[138],"thickening":[139],"adjacent":[145],"enlarged":[146],"perigastric":[147],"lymph":[148],"nodes":[149],"and/or":[150],"extramural":[151],"extension":[152],"tumor.":[154],"Pathology":[155],"from":[156,290,313],"biopsies":[158],"revealed":[159],"an":[160],"ulcerated":[161],"mixed":[162],"adeno-neuroendocrine":[163,248],"carcinoma,":[164],"establishing":[165],"diagnosis":[167,286],"primary":[169],"metastasis":[173,225],"to":[174,208,295,345],"liver.":[176],"Surgical":[177],"removal":[178],"MiNEN":[182],"deferred":[184],"favor":[186],"chemotherapy,":[188],"metastatic":[190],"disease.":[191],"He":[192],"treated":[194],"6":[196],"cycles":[197],"cisplatin/etoposide":[199],"over":[200],"5-month":[202],"period":[203],"followed":[204],"palliative":[206,325],"radiotherapy":[207],"improve":[209],"obstruction.":[210],"However,":[211],"follow":[212],"up":[213],"studies":[214],"demonstrated":[215],"no":[216,333,342],"significant":[217,343],"change":[218],"burden":[221],"worsening":[223],"(Figure":[226],"1).":[227],"Discussion:":[228],"Neuroendocrine":[229],"neoplasms":[230],"(NENs)":[231],"very":[233],"themselves":[236],"accounting":[237],"1%":[239],"malignant":[241],"GI":[242],"tumors.":[243],"MiNENs":[244],"(previously":[245],"called":[246],"carcinoma),":[249],"have":[250],"definition":[252],"least":[254],"30%":[255],"mass":[257],"contributed":[258],"each":[260],"components.":[267],"They":[268],"constitute":[269],"around":[270],"7%":[271],"all":[273],"NENs,":[275],"though":[276],"they":[277],"can":[278],"occur":[279],"throughout":[280],"digestive":[282],"tract.":[283],"As":[284],"such,":[285],"requires":[287],"histological":[288],"analysis":[289],"suspected":[291],"lesions,":[292],"addition":[294],"imaging":[296],"studies.":[297],"History":[298],"increases":[302],"risk":[304],"neoplasms.":[307],"Treatments":[308],"range":[312],"surgical":[314],"interventions":[315],"adjuvant":[317],"or":[318,324],"neoadjuvant":[319],"therapy":[320,350],"curative":[322],"intent,":[323],"options":[326],"advanced":[328],"disease;":[329],"however,":[330],"there":[331],"well-defined":[334],"guideline":[335],"management.":[338],"Our":[339],"had":[341],"response":[344],"combined":[346],"chemo":[347],"radiation":[349],"currently":[352],"planned":[355],"second-line":[357],"chemotherapy":[358],"focus":[361],"symptom":[363],"palliation.Figure":[364],"1.:":[365],"Endoscopic":[366,378],"views":[367],"Gastric":[370],"Antrum":[371],"revealing":[372],"fungating":[375],"antral":[376],"mass.":[377],"view":[379],"curvature.":[389]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-09-22T17:25:34.749102","created_date":"2023-10-20T00:00:00"}