{"id":"https://openalex.org/W4387532545","doi":"https://doi.org/10.5152/j.aott.2023.23064","title":"Adrenomedullin has no effect on segmental bone defect healing but increases bone mineral density in rat model","display_name":"Adrenomedullin has no effect on segmental bone defect healing but increases bone mineral density in rat model","publication_year":2023,"publication_date":"2023-10-11","ids":{"openalex":"https://openalex.org/W4387532545","doi":"https://doi.org/10.5152/j.aott.2023.23064","pmid":"https://pubmed.ncbi.nlm.nih.gov/37823739","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10724771"},"language":"en","primary_location":{"id":"doi:10.5152/j.aott.2023.23064","doi":"https://doi.org/10.5152/j.aott.2023.23064","is_oa":true,"landing_page_url":"https://doi.org/10.5152/j.aott.2023.23064","pdf_url":null,"source":{"id":"https://openalex.org/S104441155","display_name":"Acta Orthopaedica et Traumatologica Turcica","issn_l":"1017-995X","issn":["1017-995X","2589-1294"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","tr-dizin"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Orthopaedica et Traumatologica Turcica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.5152/j.aott.2023.23064","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029241898","display_name":"Mehmet Kaymako\u011flu","orcid":"https://orcid.org/0000-0002-3548-5672","observed_orcids":["https://orcid.org/0000-0002-3548-5672"]},"institutions":[{"id":"https://openalex.org/I15059493","display_name":"\u0130zmir University of Economics","ror":"https://ror.org/04hjr4202","country_code":"TR","type":"education","lineage":["https://openalex.org/I15059493"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Mehmet Kaymakoglu","raw_affiliation_strings":["Department of Orthopedics and Traumatology, Izmir University of Economics, Faculty of Medicine, Izmir, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics and Traumatology, Izmir University of Economics, Faculty of Medicine, Izmir, Turkey","institution_ids":["https://openalex.org/I15059493"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067228366","display_name":"Eda \u00c7iftci Dede","orcid":"https://orcid.org/0000-0001-6900-4702","observed_orcids":["https://orcid.org/0000-0001-6900-4702"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Eda Ciftci","raw_affiliation_strings":["Department of Bioengineering, Hacettepe University Institute of Natural and Applied Science, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, Hacettepe University Institute of Natural and Applied Science, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045398368","display_name":"Petek Korkusuz","orcid":"https://orcid.org/0000-0002-7553-3915","observed_orcids":["https://orcid.org/0000-0002-7553-3915"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Petek Korkusuz","raw_affiliation_strings":["Department of Histology and Embryology, Hacettepe University Faculty of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology and Embryology, Hacettepe University Faculty of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001040034","display_name":"Erdi \u00d6zdemir","orcid":"https://orcid.org/0000-0002-3147-9355","observed_orcids":["https://orcid.org/0000-0002-3147-9355"]},"institutions":[{"id":"https://openalex.org/I4210128276","display_name":"Sa\u011fl\u0131k Bilimleri \u00dcniversitesi","ror":"https://ror.org/03k7bde87","country_code":"TR","type":"education","lineage":["https://openalex.org/I4210128276"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Erdi Ozdemir","raw_affiliation_strings":["Department of Orthopedics and Traumatology, University of Health Sciences, Karabuk Training and Research Hospital, Karabuk, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics and Traumatology, University of Health Sciences, Karabuk Training and Research Hospital, Karabuk, Turkey","institution_ids":["https://openalex.org/I4210128276"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114089935","display_name":"Mehmet Ege Erden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mehmet Ege Erden","raw_affiliation_strings":["Hacettepe University Faculty of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hacettepe University Faculty of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025178521","display_name":"Egemen Turhan","orcid":"https://orcid.org/0000-0002-1971-704X","observed_orcids":["https://orcid.org/0000-0002-1971-704X"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Egemen Turhan","raw_affiliation_strings":["Department of Orthopedics and Traumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics and Traumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5029241898"],"corresponding_institution_ids":["https://openalex.org/I15059493"],"apc_list":{"value":990,"currency":"USD","value_usd":990},"apc_paid":{"value":990,"currency":"USD","value_usd":990},"fwci":0.1545,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.3512856,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"57","issue":"5","first_page":"221","last_page":"228"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.2290000021457672,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.2290000021457672,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10658","display_name":"Bone fractures and treatments","score":0.1923999935388565,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.18629999458789825,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adrenomedullin","display_name":"adrenomedullin","score":1.0},{"id":"https://openalex.org/keywords/segmental-bone-defect","display_name":"segmental bone defect","score":0.9679999947547913},{"id":"https://openalex.org/keywords/bone-regeneration","display_name":"bone regeneration","score":0.8859999775886536},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.9950000047683716},{"id":"https://openalex.org/keywords/new-bone-formation","display_name":"new bone formation","score":0.7870000004768372},{"id":"https://openalex.org/keywords/bone-volume","display_name":"bone volume","score":0.7379999756813049},{"id":"https://openalex.org/keywords/bone-surface","display_name":"bone surface","score":0.7720000147819519},{"id":"https://openalex.org/keywords/dose-dependent-effects","display_name":"dose-dependent effects","score":0.4490000009536743}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9226863384246826},{"id":"https://openalex.org/C2777152744","wikidata":"https://www.wikidata.org/wiki/Q366935","display_name":"Adrenomedullin","level":3,"score":0.8305330872535706},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.6251596808433533},{"id":"https://openalex.org/C8337478","wikidata":"https://www.wikidata.org/wiki/Q1777289","display_name":"Bone healing","level":2,"score":0.518909752368927},{"id":"https://openalex.org/C3019114686","wikidata":"https://www.wikidata.org/wiki/Q3089676","display_name":"Rat model","level":2,"score":0.4710274338722229},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.417207270860672},{"id":"https://openalex.org/C2992594941","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone mineral content","level":4,"score":0.4110494554042816},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.40767258405685425},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3736153244972229},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3555578589439392},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.27119627594947815},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.25939980149269104},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001847","descriptor_name":"Bone Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053607","descriptor_name":"Adrenomedullin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.5152/j.aott.2023.23064","doi":"https://doi.org/10.5152/j.aott.2023.23064","is_oa":true,"landing_page_url":"https://doi.org/10.5152/j.aott.2023.23064","pdf_url":null,"source":{"id":"https://openalex.org/S104441155","display_name":"Acta Orthopaedica et Traumatologica Turcica","issn_l":"1017-995X","issn":["1017-995X","2589-1294"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","tr-dizin"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Orthopaedica et Traumatologica Turcica","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10724771","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10724771","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10724771/pdf/aott-57-5-221.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Orthop Traumatol Turc","raw_type":"Text"},{"id":"pmid:37823739","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37823739","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta orthopaedica et traumatologica turcica","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:e305d510527f44e69bd6f70f0f6cfd18","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e305d510527f44e69bd6f70f0f6cfd18","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta Orthopaedica et Traumatologica Turcica, Vol 57, Iss 5, Pp 221-228 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.5152/j.aott.2023.23064","doi":"https://doi.org/10.5152/j.aott.2023.23064","is_oa":true,"landing_page_url":"https://doi.org/10.5152/j.aott.2023.23064","pdf_url":null,"source":{"id":"https://openalex.org/S104441155","display_name":"Acta Orthopaedica et Traumatologica Turcica","issn_l":"1017-995X","issn":["1017-995X","2589-1294"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2","tr-dizin"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Orthopaedica et Traumatologica Turcica","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323272","display_name":"Hacettepe \u00dcniversitesi","ror":"https://ror.org/04kwvgz42"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387532545.pdf","grobid_xml":"https://content.openalex.org/works/W4387532545.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W197424539","https://openalex.org/W1573205242","https://openalex.org/W1835700118","https://openalex.org/W1965850532","https://openalex.org/W1968184150","https://openalex.org/W1976322874","https://openalex.org/W1990694026","https://openalex.org/W1995904566","https://openalex.org/W2003493199","https://openalex.org/W2004689263","https://openalex.org/W2013165315","https://openalex.org/W2030506084","https://openalex.org/W2032905771","https://openalex.org/W2062686511","https://openalex.org/W2084300836","https://openalex.org/W2088173758","https://openalex.org/W2089364117","https://openalex.org/W2092419989","https://openalex.org/W2095068078","https://openalex.org/W2113282040","https://openalex.org/W2117626344","https://openalex.org/W2133632728","https://openalex.org/W2144828559","https://openalex.org/W2148908122","https://openalex.org/W2151343652","https://openalex.org/W2152389002","https://openalex.org/W2155995762","https://openalex.org/W2172040122","https://openalex.org/W2189210634","https://openalex.org/W2323587241","https://openalex.org/W2348305514","https://openalex.org/W2468710017","https://openalex.org/W2603791792","https://openalex.org/W2610936380","https://openalex.org/W2794780806","https://openalex.org/W2803860509","https://openalex.org/W2885672802","https://openalex.org/W2905490516","https://openalex.org/W3012154815","https://openalex.org/W3043135743"],"related_works":["https://openalex.org/W6986183382","https://openalex.org/W3149630908","https://openalex.org/W2155995762","https://openalex.org/W7098352616","https://openalex.org/W2172040122","https://openalex.org/W3033672124","https://openalex.org/W4297963091","https://openalex.org/W2067590651","https://openalex.org/W4414454132","https://openalex.org/W7100792209"],"abstract_inverted_index":{"OBJECTIVE:":[0],"This":[1],"study":[2,82,138,147,164,223,249,272],"aimed":[3],"to":[4,64,80,290],"investigate":[5],"the":[6,11,14,54,57,81,104,131,145,151,161,178,197,204,220,241,245,257,278],"effect":[7],"of":[8,13,40,56,244],"adrenomedullin":[9,41],"on":[10,33,294],"healing":[12,276],"segmental":[15,105,279],"bone":[16,49,112,120,124,239,295],"defect":[17,50,280],"in":[18,177,196,203,232,277],"a":[19,38,47,69,86,252],"rat":[20],"model.":[21],"METHODS:":[22],"Thirty-six":[23],"Wistar":[24],"rats":[25],"were":[26,107],"randomly":[27],"divided":[28],"into":[29],"6":[30],"groups":[31,66,83,139,165,224],"based":[32],"follow-up":[34],"periods":[35],"and":[36,73,97,115,123,133,148,163,192,222,234],"administered":[37,63,79,137],"dose":[39,284],"hormone.":[42],"In":[43,171],"each":[44],"group,":[45],"bilaterally,":[46],"2-mm":[48],"was":[51,62,78,175,194,217],"created":[52],"at":[53,267,282],"diaphysis":[55],"radius.":[58],"Sodium":[59],"chloride":[60],"solution":[61],"sham":[65],"3":[67,84],"times":[68,85],"week":[70],"for":[71],"4":[72],"8":[74],"weeks":[75],"intraperitoneally.":[76],"Adrenomedullin":[77,263],"week:":[87],"15":[88,91,135,179,246,268],"\u03bcg-4":[89,95],"weeks,":[90,93,96,100],"\u03bcg-8":[92,99],"30":[94,98,184,198],"respectively.":[101],"After":[102],"euthanasia,":[103],"defects":[106],"evaluated":[108],"by":[109],"histomorphometric":[110,152,233],"[new":[111],"area":[113],"(NBA)]":[114],"microtomographic":[116,172,235],"[bone":[117],"volume":[118],"(BV),":[119],"surface":[121],"(BS),":[122],"mineral":[125],"density":[126],"(BMD)]":[127],"analyses.":[128],"RESULTS:":[129],"Although":[130],"4-":[132],"8-week":[134,248],"\u03bcg":[136,180,185,199,247],"had":[140],"higher":[141,176],"NBA":[142,167],"values":[143,243],"than":[144,183,202],"other":[146],"control":[149,162,206,221,258],"groups,":[150],"analysis":[153],"did":[154],"not":[155,274],"reveal":[156],"any":[157],"statistical":[158],"difference":[159,216],"between":[160,219],"regarding":[166],"(P":[168,225],">":[169,226],".05).":[170,227],"analysis,":[173],"BV":[174],"4-week":[181,186,200,205],"group":[182,187,201,207,250,259],"(296.9":[188],"vs.":[189,209],"208.5,":[190],"P=.003),":[191],"BS":[193],"lower":[195],"(695.5":[208],"1334.7,":[210],"P=.005),":[211],"but":[212,270],"overall,":[213],"no":[214],"significant":[215,253],"found":[218],"Despite":[228],"these":[229],"minor":[230],"differences":[231],"criteria":[236],"indicating":[237],"new":[238],"formation,":[240],"BMD":[242,266],"showed":[251],"increase":[254],"compared":[255],"with":[256],"(P=.001,":[260],"respectively).":[261],"CONCLUSION:":[262],"positively":[264],"affected":[265],"\u03bcg,":[269],"this":[271],"could":[273],"show":[275],"site":[281],"different":[283],"regimens.":[285],"Further":[286],"studies":[287],"are":[288],"needed":[289],"assess":[291],"its":[292],"effects":[293],"tissue":[296],"trauma.":[297]},"counts_by_year":[{"year":2025,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-10-12T00:00:00"}