{"id":"https://openalex.org/W4387496347","doi":"https://doi.org/10.1016/j.focus.2023.100155","title":"Impact of Vaccination and Nonpharmaceutical Interventions With Possible COVID-19 Viral Evolutions Using an Agent-Based Simulation","display_name":"Impact of Vaccination and Nonpharmaceutical Interventions With Possible COVID-19 Viral Evolutions Using an Agent-Based Simulation","publication_year":2023,"publication_date":"2023-10-10","ids":{"openalex":"https://openalex.org/W4387496347","doi":"https://doi.org/10.1016/j.focus.2023.100155","pmid":"https://pubmed.ncbi.nlm.nih.gov/38130803","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10733698"},"language":"en","primary_location":{"id":"doi:10.1016/j.focus.2023.100155","doi":"https://doi.org/10.1016/j.focus.2023.100155","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.focus.2023.100155","pdf_url":"http://www.ajpmfocus.org/article/S2773065423000925/pdf","source":{"id":"https://openalex.org/S4220651960","display_name":"AJPM Focus","issn_l":"2773-0654","issn":["2773-0654"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJPM Focus","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.ajpmfocus.org/article/S2773065423000925/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103024420","display_name":"Serin Lee","orcid":"https://orcid.org/0000-0002-5343-7244","observed_orcids":["https://orcid.org/0000-0002-5343-7244","https://orcid.org/0009-0004-8179-1875"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Serin Lee","raw_affiliation_strings":["Department of Industrial & Systems Engineering, University of Washington, Seattle, Washington"],"raw_orcid":"https://orcid.org/0000-0002-5343-7244","affiliations":[{"raw_affiliation_string":"Department of Industrial & Systems Engineering, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056796690","display_name":"Zelda B. Zabinsky","orcid":"https://orcid.org/0000-0003-1838-4981","observed_orcids":["https://orcid.org/0000-0003-1838-4981"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zelda B. Zabinsky","raw_affiliation_strings":["Department of Industrial & Systems Engineering, University of Washington, Seattle, Washington"],"raw_orcid":"https://orcid.org/0000-0003-1838-4981","affiliations":[{"raw_affiliation_string":"Department of Industrial & Systems Engineering, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000463134","display_name":"Judith N. Wasserheit","orcid":"https://orcid.org/0000-0003-0408-446X","observed_orcids":["https://orcid.org/0000-0003-0408-446X"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Judith N. Wasserheit","raw_affiliation_strings":["Department of Global Health, University of Washington, Seattle, Washington","Division of Allergy & Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington"],"raw_orcid":"https://orcid.org/0000-0003-0408-446X","affiliations":[{"raw_affiliation_string":"Department of Global Health, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Division of Allergy & Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103229557","display_name":"Jennifer M. Ross","orcid":"https://orcid.org/0000-0001-5677-939X","observed_orcids":["https://orcid.org/0000-0001-5677-939X"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer M. Ross","raw_affiliation_strings":["Division of Allergy & Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington"],"raw_orcid":"https://orcid.org/0000-0001-5677-939X","affiliations":[{"raw_affiliation_string":"Division of Allergy & Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082967766","display_name":"Shi Chen","orcid":"https://orcid.org/0000-0001-8413-0870","observed_orcids":["https://orcid.org/0000-0001-8413-0870"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shi Chen","raw_affiliation_strings":["Department of Information Systems and Operations Management, Foster School of Business, University of Washington, Seattle, Washington"],"raw_orcid":"https://orcid.org/0000-0001-8413-0870","affiliations":[{"raw_affiliation_string":"Department of Information Systems and Operations Management, Foster School of Business, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100449808","display_name":"Shan Liu","orcid":"https://orcid.org/0000-0003-1459-8923","observed_orcids":["https://orcid.org/0000-0003-1459-8923","https://orcid.org/0000-0002-0910-9657","https://orcid.org/0000-0002-8443-6738"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shan Liu","raw_affiliation_strings":["Department of Industrial & Systems Engineering, University of Washington, Seattle, Washington"],"raw_orcid":"https://orcid.org/0000-0003-1459-8923","affiliations":[{"raw_affiliation_string":"Department of Industrial & Systems Engineering, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5103024420"],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":{"value":1800,"currency":"USD","value_usd":1800},"apc_paid":{"value":1800,"currency":"USD","value_usd":1800},"fwci":0.4202,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.59411818,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"3","issue":"1","first_page":"100155","last_page":"100155"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10410","display_name":"COVID-19 epidemiological studies","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10410","display_name":"COVID-19 epidemiological studies","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10482","display_name":"Mathematical and Theoretical Epidemiology and Ecology Models","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9980000257492065},{"id":"https://openalex.org/keywords/sars-cov-2-variants","display_name":"SARS-CoV-2 variants","score":0.9890000224113464},{"id":"https://openalex.org/keywords/viral-evolution","display_name":"viral evolution","score":0.5989999771118164},{"id":"https://openalex.org/keywords/non-pharmaceutical-interventions","display_name":"non-pharmaceutical interventions","score":0.8949999809265137},{"id":"https://openalex.org/keywords/immune-evasion","display_name":"immune evasion","score":0.7310000061988831},{"id":"https://openalex.org/keywords/covid-19-mortality","display_name":"COVID-19 mortality","score":0.9089999794960022},{"id":"https://openalex.org/keywords/agent-based-modeling","display_name":"agent-based modeling","score":0.8199999928474426},{"id":"https://openalex.org/keywords/epidemic-modeling","display_name":"epidemic modeling","score":0.5220000147819519}],"concepts":[{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.7714574933052063},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.6398459672927856},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.5938747525215149},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.5501712560653687},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5356324315071106},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5229688286781311},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4329652786254883},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08288604021072388},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.07478448748588562},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.05114582180976868},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1016/j.focus.2023.100155","doi":"https://doi.org/10.1016/j.focus.2023.100155","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.focus.2023.100155","pdf_url":"http://www.ajpmfocus.org/article/S2773065423000925/pdf","source":{"id":"https://openalex.org/S4220651960","display_name":"AJPM Focus","issn_l":"2773-0654","issn":["2773-0654"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJPM Focus","raw_type":"journal-article"},{"id":"doi:10.2139/ssrn.4382858","doi":"https://doi.org/10.2139/ssrn.4382858","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.4382858","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10733698","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10733698","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10733698/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJPM Focus","raw_type":"Text"},{"id":"pmid:38130803","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38130803","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJPM focus","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:11fc9aaf719646168c47fca89447bb6f","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/11fc9aaf719646168c47fca89447bb6f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"AJPM Focus, Vol 3, Iss 1, Pp 100155- (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.focus.2023.100155","doi":"https://doi.org/10.1016/j.focus.2023.100155","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.focus.2023.100155","pdf_url":"http://www.ajpmfocus.org/article/S2773065423000925/pdf","source":{"id":"https://openalex.org/S4220651960","display_name":"AJPM Focus","issn_l":"2773-0654","issn":["2773-0654"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJPM Focus","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1641819385","display_name":null,"funder_award_id":"1935403","funder_id":"https://openalex.org/F4320337391","funder_display_name":"Division of Civil, Mechanical and Manufacturing Innovation"},{"id":"https://openalex.org/G311239485","display_name":"Optimizing Vaccination Incentives to Prevent Disease Outbreaks","funder_award_id":"1935403","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7845708211","display_name":"Decision Modeling to Inform Timely Action During the COVID-19 Pandemic","funder_award_id":"GBMF9634","funder_id":"https://openalex.org/F4320306202","funder_display_name":"Gordon and Betty Moore Foundation"},{"id":"https://openalex.org/G8343818084","display_name":null,"funder_award_id":"COVID-19","funder_id":"https://openalex.org/F4320310145","funder_display_name":"Johns Hopkins University"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306202","display_name":"Gordon and Betty Moore Foundation","ror":"https://ror.org/006wxqw41"},{"id":"https://openalex.org/F4320310145","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95"},{"id":"https://openalex.org/F4320337391","display_name":"Division of Civil, Mechanical and Manufacturing Innovation","ror":"https://ror.org/028yd4c30"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387496347.pdf","grobid_xml":"https://content.openalex.org/works/W4387496347.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1510501987","https://openalex.org/W1995395876","https://openalex.org/W3034304416","https://openalex.org/W3034823740","https://openalex.org/W3093348809","https://openalex.org/W3102798166","https://openalex.org/W3119688612","https://openalex.org/W3127266572","https://openalex.org/W3136670839","https://openalex.org/W3154237281","https://openalex.org/W3156257646","https://openalex.org/W3157730684","https://openalex.org/W3168119768","https://openalex.org/W3171681979","https://openalex.org/W3192238408","https://openalex.org/W3200434200","https://openalex.org/W3203507661","https://openalex.org/W3206303627","https://openalex.org/W3211430680","https://openalex.org/W4200051864","https://openalex.org/W4200560430","https://openalex.org/W4205497912","https://openalex.org/W4206533311","https://openalex.org/W4211118466","https://openalex.org/W4211242522","https://openalex.org/W4213069125","https://openalex.org/W4220692166","https://openalex.org/W4225297917","https://openalex.org/W4226090490","https://openalex.org/W4226377601","https://openalex.org/W4280517779","https://openalex.org/W4280643719","https://openalex.org/W4281557772","https://openalex.org/W4282958946","https://openalex.org/W4287509931","https://openalex.org/W4291448124","https://openalex.org/W4296026861","https://openalex.org/W4298005056","https://openalex.org/W4308783275","https://openalex.org/W4309112350","https://openalex.org/W4317356311","https://openalex.org/W4318016227","https://openalex.org/W4321019564","https://openalex.org/W4323828034","https://openalex.org/W6777223799","https://openalex.org/W6781026791","https://openalex.org/W6802531607","https://openalex.org/W6804688003","https://openalex.org/W6841702087","https://openalex.org/W6846076660","https://openalex.org/W6847049024"],"related_works":["https://openalex.org/W4281684567","https://openalex.org/W4220933713","https://openalex.org/W3164626794","https://openalex.org/W4221096251","https://openalex.org/W3156342727","https://openalex.org/W3139388973","https://openalex.org/W4386902805","https://openalex.org/W4319311659","https://openalex.org/W4280499546","https://openalex.org/W4399860478"],"abstract_inverted_index":{"Introduction:":[0],"The":[1,60,97],"COVID-19":[2,28,49,58,201,228,267],"pandemic":[3,29],"continues":[4],"with":[5,109,140,160],"highly":[6,210],"contagious":[7,214],"variants":[8],"and":[9,21,53,86,92,188,213,234,243,261],"waning":[10],"immunity.":[11,190],"As":[12],"the":[13,27,46,65,102,127,141,179,193,225,230,257],"virus":[14,205],"keeps":[15],"evolving":[16],"to":[17,44,64,209,223,229],"be":[18,31],"more":[19],"infectious":[20],"immune":[22,87,114,121,211],"evasive,":[23],"some":[24],"question":[25],"whether":[26],"can":[30],"managed":[32],"through":[33],"sustainable":[34],"public":[35],"health":[36],"measures.":[37],"Methods:":[38],"We":[39,74,191],"developed":[40],"an":[41,161],"agent-based":[42],"simulation":[43,98],"explore":[45],"impact":[47],"of":[48,104,182,196,204,227,232],"mutations,":[50],"periodic":[51,130,144,241],"vaccinations,":[52],"nonpharmaceutical":[54,150,167,197,246],"interventions":[55,198],"on":[56,78],"reducing":[57,200],"deaths.":[59],"model":[61],"is":[62,99],"calibrated":[63],"greater":[66],"Seattle":[67],"area":[68],"by":[69,137,157],"observing":[70],"local":[71],"epidemic":[72],"data.":[73],"perform":[75],"scenario":[76],"analyses":[77],"viral":[79],"mutations":[80],"that":[81,185,240],"change":[82],"infectiousness,":[83],"disease":[84],"severity,":[85],"evasiveness":[88],"from":[89,123],"previous":[90,117],"infections":[91],"vaccination":[93,131,145],"every":[94],"6":[95],"months.":[96],"run":[100],"until":[101],"end":[103],"year":[105],"2023.":[106],"Results:":[107],"Variants":[108],"increased":[110,113],"infectivity":[111],"or":[112],"evasion":[115],"dominate":[116],"strains.":[118],"With":[119],"enhanced":[120,187],"protection":[122],"a":[124,165,172,244,265],"pancoronavirus":[125,183],"vaccine,":[126],"most":[128,142,217],"optimistic":[129],"rate":[132],"reduces":[133,153],"average":[134,154],"total":[135,155],"deaths":[136,156,202],"44.6%":[138],"compared":[139,159],"pessimistic":[143],"rate.":[146],"A":[147],"strict":[148],"threshold":[149,245],"intervention":[151,168,247],"policy":[152,169,248],"71.3%":[158],"open":[162],"society,":[163],"whereas":[164],"moderate":[166],"results":[170],"in":[171,199,219,251,263],"33.6%":[173],"reduction.":[174],"Conclusions:":[175],"Our":[176],"findings":[177,238],"highlight":[178],"potential":[180],"benefits":[181],"vaccines":[184],"offer":[186],"longer-lasting":[189],"emphasize":[192],"crucial":[194],"role":[195],"regardless":[203],"mutation":[206],"scenarios.":[207],"Owing":[208],"evasive":[212],"SARS-CoV-2":[215],"variants,":[216],"scenarios":[218],"this":[220,253],"study":[221],"fail":[222],"reduce":[224],"mortality":[226],"level":[231],"influenza":[233],"pneumonia.":[235],"However,":[236],"our":[237],"indicate":[239],"vaccinations":[242],"may":[249],"succeed":[250],"achieving":[252],"goal.":[254],"This":[255],"indicates":[256],"need":[258],"for":[259],"caution":[260],"vigilance":[262],"managing":[264],"continuing":[266],"epidemic.":[268]},"counts_by_year":[{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2023-10-11T00:00:00"}