{"id":"https://openalex.org/W4387433271","doi":"https://doi.org/10.1210/jendso/bvad114.511","title":"SAT214 A Rare Case Of Biopsy-proven Non-uremic Calciphylaxis In A Patient With Secondary Hyperparathyroidism","display_name":"SAT214 A Rare Case Of Biopsy-proven Non-uremic Calciphylaxis In A Patient With Secondary Hyperparathyroidism","publication_year":2023,"publication_date":"2023-10-01","ids":{"openalex":"https://openalex.org/W4387433271","doi":"https://doi.org/10.1210/jendso/bvad114.511"},"language":"en","primary_location":{"id":"doi:10.1210/jendso/bvad114.511","doi":"https://doi.org/10.1210/jendso/bvad114.511","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1210/jendso/bvad114.511","pdf_url":null,"source":{"id":"https://openalex.org/S2735747656","display_name":"Journal of the Endocrine Society","issn_l":"2472-1972","issn":["2472-1972"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315851","host_organization_name":"Endocrine Society","host_organization_lineage":["https://openalex.org/P4310315851"],"host_organization_lineage_names":["Endocrine Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Endocrine Society","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1210/jendso/bvad114.511","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011215726","display_name":"Ufeh Annabel Ogar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799932517","display_name":"John H. Stroger, Jr. Hospital of Cook County","ror":"https://ror.org/05626m728","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799932517"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ufeh Annabel Ogar","raw_affiliation_strings":["John H Stroger Jr Hospital of Cook County , Chicago, IL , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John H Stroger Jr Hospital of Cook County , Chicago, IL , USA","institution_ids":["https://openalex.org/I2799932517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001505293","display_name":"Ayobami Gbenga Olafimihan","orcid":"https://orcid.org/0000-0003-3868-747X","observed_orcids":["https://orcid.org/0000-0003-3868-747X"]},"institutions":[{"id":"https://openalex.org/I2799932517","display_name":"John H. Stroger, Jr. Hospital of Cook County","ror":"https://ror.org/05626m728","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799932517"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ayobami Gbenga Olafimihan","raw_affiliation_strings":["John H Stroger Jr Hospital of Cook County , Chicago, IL , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John H Stroger Jr Hospital of Cook County , Chicago, IL , USA","institution_ids":["https://openalex.org/I2799932517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001305511","display_name":"Iriagbonse Asemota","orcid":"https://orcid.org/0000-0002-8843-8204","observed_orcids":["https://orcid.org/0000-0002-8843-8204"]},"institutions":[{"id":"https://openalex.org/I2799932517","display_name":"John H. Stroger, Jr. Hospital of Cook County","ror":"https://ror.org/05626m728","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799932517"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Iriagbonse Asemota","raw_affiliation_strings":["John H Stroger Hosp of Cook County , Chicago, IL , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John H Stroger Hosp of Cook County , Chicago, IL , USA","institution_ids":["https://openalex.org/I2799932517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021989744","display_name":"Ellil Krishnaraju","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799932517","display_name":"John H. Stroger, Jr. Hospital of Cook County","ror":"https://ror.org/05626m728","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799932517"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ellil Krishnaraju","raw_affiliation_strings":["John H. Stroger Jr. Hospital of Cook County , Chicago, IL , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John H. Stroger Jr. Hospital of Cook County , Chicago, IL , USA","institution_ids":["https://openalex.org/I2799932517"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111052488","display_name":"Akuchi Okafor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akuchi Okafor","raw_affiliation_strings":["Alex Ekueme University Teaching Hospital , Abakaliki , Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alex Ekueme University Teaching Hospital , Abakaliki , Nigeria","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3100,"currency":"USD","value_usd":3100},"apc_paid":{"value":3100,"currency":"USD","value_usd":3100},"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"Supplement_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12924","display_name":"Dermatological and Skeletal Disorders","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calciphylaxis","display_name":"calciphylaxis","score":0.8790000081062317},{"id":"https://openalex.org/keywords/secondary-hyperparathyroidism","display_name":"secondary hyperparathyroidism","score":0.9190000295639038},{"id":"https://openalex.org/keywords/skin-biopsy","display_name":"skin biopsy","score":0.5669999718666077},{"id":"https://openalex.org/keywords/metastatic-calcification","display_name":"metastatic calcification","score":0.6460000276565552},{"id":"https://openalex.org/keywords/alcoholism","display_name":"alcoholism","score":0.6129999756813049},{"id":"https://openalex.org/keywords/wound-debridement","display_name":"wound debridement","score":0.6200000047683716},{"id":"https://openalex.org/keywords/vitamin-d-deficiency","display_name":"vitamin D deficiency","score":0.5199999809265137},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.44600000977516174},{"id":"https://openalex.org/keywords/alcoholic-liver-disease","display_name":"alcoholic liver disease","score":0.4690000116825104},{"id":"https://openalex.org/keywords/differential-diagnosis-of-skin-lesions","display_name":"differential diagnosis of skin lesions","score":0.5059999823570251},{"id":"https://openalex.org/keywords/vancomycin","display_name":"vancomycin","score":0.35899999737739563},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.36500000953674316}],"concepts":[{"id":"https://openalex.org/C2776954043","wikidata":"https://www.wikidata.org/wiki/Q1026326","display_name":"Calciphylaxis","level":3,"score":0.8925138711929321},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8887494802474976},{"id":"https://openalex.org/C2775945674","wikidata":"https://www.wikidata.org/wiki/Q1344835","display_name":"Hyperparathyroidism","level":2,"score":0.5041497945785522},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5040158629417419},{"id":"https://openalex.org/C2776036575","wikidata":"https://www.wikidata.org/wiki/Q1641062","display_name":"Hyperphosphatemia","level":3,"score":0.4997549057006836},{"id":"https://openalex.org/C2776635150","wikidata":"https://www.wikidata.org/wiki/Q13365776","display_name":"Uremia","level":2,"score":0.4613703489303589},{"id":"https://openalex.org/C2778838027","wikidata":"https://www.wikidata.org/wiki/Q3622611","display_name":"Secondary hyperparathyroidism","level":4,"score":0.4600841999053955},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.4141852855682373},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.4017590880393982},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3197539448738098},{"id":"https://openalex.org/C2780309369","wikidata":"https://www.wikidata.org/wiki/Q933382","display_name":"Calcification","level":2,"score":0.200408935546875},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.0},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1210/jendso/bvad114.511","doi":"https://doi.org/10.1210/jendso/bvad114.511","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1210/jendso/bvad114.511","pdf_url":null,"source":{"id":"https://openalex.org/S2735747656","display_name":"Journal of the Endocrine Society","issn_l":"2472-1972","issn":["2472-1972"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315851","host_organization_name":"Endocrine Society","host_organization_lineage":["https://openalex.org/P4310315851"],"host_organization_lineage_names":["Endocrine Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Endocrine Society","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10554023","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10554023","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10554023/pdf/bvad114.511.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Endocr Soc","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1210/jendso/bvad114.511","doi":"https://doi.org/10.1210/jendso/bvad114.511","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1210/jendso/bvad114.511","pdf_url":null,"source":{"id":"https://openalex.org/S2735747656","display_name":"Journal of the Endocrine Society","issn_l":"2472-1972","issn":["2472-1972"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315851","host_organization_name":"Endocrine Society","host_organization_lineage":["https://openalex.org/P4310315851"],"host_organization_lineage_names":["Endocrine Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Endocrine Society","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387433271.pdf","grobid_xml":"https://content.openalex.org/works/W4387433271.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7131285389","https://openalex.org/W4312665961","https://openalex.org/W2305769544","https://openalex.org/W1703923883","https://openalex.org/W4392405178","https://openalex.org/W3016581909","https://openalex.org/W4385951748","https://openalex.org/W2052399629","https://openalex.org/W2907390083","https://openalex.org/W4403831494"],"abstract_inverted_index":{"Abstract":[0],"Disclosure:":[1],"U.A.":[2],"Ogar:":[3],"None.":[4,7,10,13,16],"A.G.":[5],"Olafimihan:":[6],"I.":[8],"Asemota:":[9],"E.":[11],"Krishnaraju:":[12],"A.":[14],"Okafor:":[15],"Introduction:":[17],"Calciphylaxis,":[18],"also":[19],"known":[20],"as":[21,36,108,346],"calcific":[22],"uremic":[23],"arteriolopathy,":[24],"is":[25,66,72,76,352],"a":[26,96,118,133,155,176,314,321],"rare,":[27],"lethal,":[28],"metastatic":[29],"calcification":[30],"involving":[31],"cutaneous":[32],"microvasculature":[33],"that":[34],"presents":[35],"painful":[37],"necrotic":[38],"skin":[39,198,221,249],"lesions.":[40],"It":[41],"typically":[42],"occurs":[43],"in":[44,103,109,347,363],"patients":[45,104],"with":[46,83,105,117,132,207,244,282,300,378],"end-stage":[47],"kidney":[48,55],"disease":[49],"(ESKD),":[50],"renal":[51,58],"transplant,":[52],"or":[53,148],"acute":[54],"injury":[56],"requiring":[57],"replacement":[59],"therapy.":[60],"Calciphylaxis":[61],"occurring":[62],"without":[63],"these":[64],"comorbidities":[65],"termed":[67],"non-uremic":[68],"calciphylaxis":[69],"(NUC),":[70],"which":[71],"rarer.":[73],"NUC\u2019s":[74],"etiology":[75],"unclear":[77],"but":[78,377],"it":[79],"has":[80,313],"been":[81],"associated":[82],"hyperparathyroidism,":[84,107],"malignancies,":[85],"alcohol":[86,128],"liver":[87],"disease,":[88,340],"and":[89,127,188,214,222,253,270,273,285,304,319,331,344,357],"connective":[90],"tissue":[91,224],"disorders.":[92],"There":[93],"are":[94,359,387],"only":[95],"few":[97],"reported":[98],"cases":[99],"of":[100,120,136,172,239,257,324,333],"biopsy-proven":[101],"NUC":[102,312],"secondary":[106],"our":[110,348],"patient.":[111,349],"Clinical":[112],"Case:":[113],"A":[114,248],"63-year-old":[115],"female":[116],"history":[119,135],"COPD":[121],"on":[122],"home":[123],"oxygen":[124],"therapy,":[125],"smoking,":[126],"use":[129],"disorder":[130],"presented":[131],"four-day":[134],"severe,":[137],"painful,":[138],"purplish":[139],"left":[140,162],"thigh":[141,163],"rash.":[142],"She":[143],"had":[144,200,309],"no":[145],"recent":[146],"trauma":[147],"insect":[149],"bite.":[150],"Her":[151,276],"physical":[152],"exam":[153],"showed":[154],"large":[156],"(6x10":[157],"cm),":[158],"tender,":[159],"distal":[160],"anterior":[161],"bruise.":[164],"Laboratory":[165],"findings":[166],"were":[167],"significant":[168],"for":[169,219],"elevated":[170,189,306],"creatine":[171],"4.3":[173],"mg/dL":[174],"from":[175],"normal":[177,182],"baseline":[178],"creatinine":[179,308],"(0.6":[180],"mg/dL),":[181],"serum":[183,307],"corrected":[184],"calcium":[185],"(10.1":[186],"mg/dL)":[187],"phosphate":[190],"(4.7mg/dL).":[191],"Three":[192],"days":[193],"following":[194],"her":[195,292,305],"admission,":[196],"the":[197,232,245],"lesion":[199],"progressed":[201],"into":[202],"multiple":[203],"brown":[204],"coalescing":[205],"bullae":[206],"central":[208],"ulceration,":[209],"collarette,":[210],"surrounding":[211],"erythema,":[212],"warmth,":[213],"induration.":[215],"Due":[216],"to":[217,296,327,361,365],"concern":[218],"possible":[220],"soft":[223],"infection,":[225,241],"empiric":[226],"vancomycin":[227],"therapy":[228],"was":[229,236,251,255,294],"started.":[230],"However,":[231],"overall":[233],"clinical":[234,325],"picture":[235],"not":[237],"convincing":[238],"an":[240],"necessitating":[242],"consultation":[243],"Dermatology":[246],"team.":[247],"biopsy":[250,351],"recommended,":[252],"this":[254],"diagnostic":[256],"calciphylaxis.":[258],"Further":[259],"testing":[260],"revealed":[261],"hyperparathyroidism":[262],"(202pg/ml),":[263],"low":[264],"25":[265],"hydroxy":[266],"Vitamin":[267],"D":[268],"(12ng/ml),":[269],"negative":[271],"autoimmune":[272],"thrombophilia":[274],"workup.":[275],"treatment":[277,371],"plan":[278],"included":[279],"wound":[280,293,302,355],"care":[281,356],"debridement,":[283],"analgesia,":[284],"interdisciplinary":[286],"clinic":[287],"follow-up.":[288],"During":[289],"outpatient":[290],"follow-up,":[291],"seen":[295],"be":[297],"slowly":[298],"healing":[299],"daily":[301],"dressing,":[303],"resolved.":[310],"Conclusion:":[311],"high":[315,322],"mortality":[316],"rate":[317],"(52%)":[318],"requires":[320],"index":[323],"suspicion":[326],"ensure":[328],"prompt":[329],"diagnosis":[330],"initiation":[332],"treatment.":[334],"Differential":[335],"diagnoses":[336],"include":[337],"atherosclerotic":[338],"vascular":[339],"vasculitis,":[341],"hypercoagulable":[342],"disorders,":[343],"cellulitis":[345],"Skin":[350],"diagnostic.":[353],"Aggressive":[354],"analgesia":[358],"pivotal":[360],"treatment,":[362],"addition":[364],"addressing":[366],"underlying":[367],"precipitating":[368],"conditions.":[369],"Other":[370],"options":[372],"like":[373],"sodium":[374],"thiosulphate":[375],"exist":[376],"uncertain":[379],"outcomes.":[380],"Efforts":[381],"geared":[382],"at":[383],"definitive":[384],"therapeutic":[385],"modalities":[386],"needed.":[388],"Presentation:":[389],"Saturday,":[390],"June":[391],"17,":[392],"2023":[393]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2023-10-09T00:00:00"}