{"id":"https://openalex.org/W4387433170","doi":"https://doi.org/10.1210/jendso/bvad114.1731","title":"FRI424 Allopregnanolone Levels Are Elevated in the Follicular Phase and Predict Premenstrual Depression and Anxiety Symptom Severity in Women with Menstrually Related Mood Disorder","display_name":"FRI424 Allopregnanolone Levels Are Elevated in the Follicular Phase and Predict Premenstrual Depression and Anxiety Symptom Severity in Women with Menstrually Related Mood Disorder","publication_year":2023,"publication_date":"2023-10-01","ids":{"openalex":"https://openalex.org/W4387433170","doi":"https://doi.org/10.1210/jendso/bvad114.1731"},"language":"en","primary_location":{"id":"doi:10.1210/jendso/bvad114.1731","doi":"https://doi.org/10.1210/jendso/bvad114.1731","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1210/jendso/bvad114.1731","pdf_url":"https://academic.oup.com/jes/article-pdf/7/Supplement_1/bvad114.1731/51903416/bvad114.1731.pdf","source":{"id":"https://openalex.org/S2735747656","display_name":"Journal of the Endocrine Society","issn_l":"2472-1972","issn":["2472-1972"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315851","host_organization_name":"Endocrine Society","host_organization_lineage":["https://openalex.org/P4310315851"],"host_organization_lineage_names":["Endocrine Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Endocrine Society","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/jes/article-pdf/7/Supplement_1/bvad114.1731/51903416/bvad114.1731.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007527084","display_name":"Allison Kimball","orcid":"https://orcid.org/0000-0002-6750-644X","observed_orcids":["https://orcid.org/0000-0002-6750-644X"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allison Kimball","raw_affiliation_strings":["Massachusetts General Hospital , Boston, MA , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital , Boston, MA , USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054826897","display_name":"Jenna G. Bourassa","orcid":"https://orcid.org/0009-0000-7337-5944","observed_orcids":["https://orcid.org/0009-0000-7337-5944"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jenna Bourassa","raw_affiliation_strings":["Massachusetts General Hospital , Boston, MA , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital , Boston, MA , USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009692846","display_name":"Mark L Chicote","orcid":"https://orcid.org/0000-0003-3155-2468","observed_orcids":["https://orcid.org/0000-0003-3155-2468"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Chicote","raw_affiliation_strings":["Massachusetts General Hospital , Boston, MA , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital , Boston, MA , USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067016582","display_name":"Anu V. Gerweck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anu V Gerweck","raw_affiliation_strings":["Massachusetts General Hospital , Boston, MA , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital , Boston, MA , USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062686177","display_name":"Laura E. Dichtel","orcid":"https://orcid.org/0000-0001-6989-2308","observed_orcids":["https://orcid.org/0000-0001-6989-2308"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura E Dichtel","raw_affiliation_strings":["Massachusetts General Hospital , Boston, MA , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital , Boston, MA , USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052169338","display_name":"Karen Klahr Miller","orcid":"https://orcid.org/0000-0001-9438-2449","observed_orcids":["https://orcid.org/0000-0001-9438-2449"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen K Miller","raw_affiliation_strings":["Massachusetts General Hospital , Boston, MA , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital , Boston, MA , USA","institution_ids":["https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210087915"],"apc_list":{"value":3100,"currency":"USD","value_usd":3100},"apc_paid":{"value":3100,"currency":"USD","value_usd":3100},"fwci":0.255,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.57318376,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"7","issue":"Supplement_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12054","display_name":"Menstrual Health and Disorders","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12054","display_name":"Menstrual Health and Disorders","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10786","display_name":"Maternal Mental Health During Pregnancy and Postpartum","score":0.008700000122189522,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allopregnanolone","display_name":"allopregnanolone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/premenstrual-dysphoric-disorder","display_name":"premenstrual dysphoric disorder","score":0.9990000128746033},{"id":"https://openalex.org/keywords/follicular-phase","display_name":"follicular phase","score":0.9229999780654907},{"id":"https://openalex.org/keywords/luteal-phase","display_name":"luteal phase","score":0.9900000095367432},{"id":"https://openalex.org/keywords/depression-severity","display_name":"depression severity","score":0.6309999823570251},{"id":"https://openalex.org/keywords/anxiety-levels","display_name":"anxiety levels","score":0.8169999718666077},{"id":"https://openalex.org/keywords/gaba-a-receptor","display_name":"GABAA receptor","score":0.7099999785423279},{"id":"https://openalex.org/keywords/progesterone-metabolites","display_name":"progesterone metabolites","score":0.871999979019165},{"id":"https://openalex.org/keywords/menstrual-cycle","display_name":"menstrual cycle","score":0.5879999995231628},{"id":"https://openalex.org/keywords/plasma-steroids","display_name":"plasma steroids","score":0.503000020980835},{"id":"https://openalex.org/keywords/women-s-mental-health","display_name":"women's mental health","score":0.7279999852180481},{"id":"https://openalex.org/keywords/neurosteroids","display_name":"neurosteroids","score":0.4359999895095825},{"id":"https://openalex.org/keywords/luteinizing-hormone-surge","display_name":"luteinizing hormone surge","score":0.35199999809265137}],"concepts":[{"id":"https://openalex.org/C2778338918","wikidata":"https://www.wikidata.org/wiki/Q2482223","display_name":"Allopregnanolone","level":5,"score":0.949009895324707},{"id":"https://openalex.org/C2778015638","wikidata":"https://www.wikidata.org/wiki/Q2728811","display_name":"Premenstrual dysphoric disorder","level":4,"score":0.903576672077179},{"id":"https://openalex.org/C143228043","wikidata":"https://www.wikidata.org/wiki/Q2363481","display_name":"Luteal phase","level":3,"score":0.7864688038825989},{"id":"https://openalex.org/C187785154","wikidata":"https://www.wikidata.org/wiki/Q5464664","display_name":"Follicular phase","level":2,"score":0.6109311580657959},{"id":"https://openalex.org/C2779058012","wikidata":"https://www.wikidata.org/wiki/Q83864","display_name":"Menstrual cycle","level":3,"score":0.5646902322769165},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5448534488677979},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.5115745663642883},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.49359071254730225},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4879254996776581},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.47972312569618225},{"id":"https://openalex.org/C44796713","wikidata":"https://www.wikidata.org/wiki/Q2659374","display_name":"Neuroactive steroid","level":4,"score":0.47484448552131653},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.45638635754585266},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.4197492301464081},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3991090655326843},{"id":"https://openalex.org/C168258287","wikidata":"https://www.wikidata.org/wiki/Q60147","display_name":"GABAA receptor","level":3,"score":0.1427897810935974},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.11446362733840942},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.10267791152000427},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1210/jendso/bvad114.1731","doi":"https://doi.org/10.1210/jendso/bvad114.1731","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1210/jendso/bvad114.1731","pdf_url":"https://academic.oup.com/jes/article-pdf/7/Supplement_1/bvad114.1731/51903416/bvad114.1731.pdf","source":{"id":"https://openalex.org/S2735747656","display_name":"Journal of the Endocrine Society","issn_l":"2472-1972","issn":["2472-1972"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315851","host_organization_name":"Endocrine Society","host_organization_lineage":["https://openalex.org/P4310315851"],"host_organization_lineage_names":["Endocrine Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Endocrine Society","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10554265","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10554265","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10554265/pdf/bvad114.1731.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Endocr Soc","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1210/jendso/bvad114.1731","doi":"https://doi.org/10.1210/jendso/bvad114.1731","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1210/jendso/bvad114.1731","pdf_url":"https://academic.oup.com/jes/article-pdf/7/Supplement_1/bvad114.1731/51903416/bvad114.1731.pdf","source":{"id":"https://openalex.org/S2735747656","display_name":"Journal of the Endocrine Society","issn_l":"2472-1972","issn":["2472-1972"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315851","host_organization_name":"Endocrine Society","host_organization_lineage":["https://openalex.org/P4310315851"],"host_organization_lineage_names":["Endocrine Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Endocrine Society","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387433170.pdf","grobid_xml":"https://content.openalex.org/works/W4387433170.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4404773890","https://openalex.org/W2083552615","https://openalex.org/W2038415949","https://openalex.org/W4256467328","https://openalex.org/W2989076120","https://openalex.org/W199080563","https://openalex.org/W7017353600","https://openalex.org/W1966126679","https://openalex.org/W1891610553","https://openalex.org/W2766874411"],"abstract_inverted_index":{"Abstract":[0],"Disclosure:":[1],"A.":[2],"Kimball:":[3],"None.":[4,7,10,13,52],"J.":[5],"Bourassa:":[6],"M.":[8],"Chicote:":[9],"A.V.":[11],"Gerweck:":[12],"L.E.":[14],"Dichtel:":[15],"Other;":[16],"Self;":[17],"Dr.":[18],"Dichtel":[19],"is":[20,67,84,91],"a":[21,92,98,466],"Mass":[22],"General":[23],"Brigham":[24],"(MGB)":[25],"Innovation":[26],"Fellow":[27],"hosted":[28],"by":[29,40,69,151,251],"Third":[30],"Rock":[31],"Ventures.":[32],"Financial":[33],"interests":[34],"were":[35,229,249,261,277,359,379,423],"reviewed":[36],"and":[37,42,64,97,106,164,188,219,225,238,273,320,349,390,396,472],"are":[38,254],"managed":[39],"MGH":[41],"MGB":[43],"in":[44,73,127,137,142,146,176,285,293,311,323,334,340,351,362,375,385,400,425,429,437,455,460,474],"accordance":[45],"with":[46,104,139,153,159,167,381,431,444,477],"their":[47],"COI":[48],"policies.":[49],"K.K.":[50],"Miller:":[51],"Menstrually":[53],"related":[54],"mood":[55],"disorder":[56,62],"(MRMD),":[57],"which":[58,419],"includes":[59],"premenstrual":[60,169,470],"dysphoric":[61],"(PMDD)":[63],"subthreshold":[65,220],"PMDD,":[66],"marked":[68],"severe":[70],"psychiatric":[71,172],"impairment":[72],"the":[74,79,87,117,122,140,147,177,232,264,294,302,305,335,369,376,386,401,426,438,456],"late":[75,148,189,295,391,402,439],"luteal":[76,125,149,190,296,370,392,403,440],"phase":[77,126,150,297,337,378,395,404,428,441],"of":[78,95,208,210,235,267,325,353,416,451],"menstrual":[80],"cycle,":[81],"but":[82],"little":[83],"known":[85],"about":[86],"mechanisms":[88],"responsible.":[89],"Allopregnanolone":[90],"neuroactive":[93,363,417],"metabolite":[94],"progesterone":[96,452],"potent":[99],"GABAA":[100],"receptor":[101],"allosteric":[102],"activator":[103],"antidepressant":[105,421],"anxiolytic":[107],"properties.":[108],"We":[109,130,155],"have":[110,420],"shown":[111],"that":[112,132,414,448],"allopregnanolone":[113,133,307,373,454,462],"levels":[114,134,248,365,374,415],"increase,":[115],"while":[116],"allopregnanolone/progesterone":[118,332],"ratio":[119,333],"decreases,":[120],"from":[121],"follicular":[123,303,336,377,427,457],"to":[124,214,409,453,469],"healthy":[128,165],"women.":[129,329,357],"hypothesized":[131],"would":[135],"decrease":[136],"association":[138],"increase":[141],"depression":[143,383,436,471],"severity":[144,228,282,384,399],"experienced":[145],"women":[152,158,430,476],"MRMD.":[154,478],"studied":[156],"23":[157],"regular":[160],"menses":[161],"[MRMD":[162],"(n=9)":[163],"controls":[166],"no":[168,360],"symptoms":[170],"or":[171,202],"history":[173],"(HC)":[174],"(n=14)]":[175],"mid-follicular":[178],"(cycle":[179],"day":[180],"6-10),":[181],"mid-luteal":[182,387],"(5-9":[183],"days":[184,192],"after":[185,193],"LH":[186,194],"surge),":[187],"(9-13":[191],"surge)":[195],"phases.":[196],"No":[197],"subjects":[198],"took":[199],"gonadal":[200],"steroids":[201],"psychotropic":[203],"medications.":[204],"The":[205,330],"Daily":[206],"Record":[207],"Severity":[209],"Problems":[211],"was":[212,283,309,338],"used":[213],"diagnosed":[215],"PMDD":[216,221],"(\u22655":[217],"symptoms)":[218],"(1-4":[222],"symptoms).":[223],"Depression":[224,281],"anxiety":[226,398,473],"symptom":[227],"assessed":[230],"using":[231],"Quick":[233],"Inventory":[234],"Depressive":[236],"Symptomatology":[237],"Generalized":[239],"Anxiety":[240],"Disorder":[241],"7-item":[242],"Scale,":[243],"respectively.":[244],"Fasting":[245],"plasma":[246],"hormone":[247],"measured":[250],"GC/MS.":[252],"Data":[253],"presented":[255],"as":[256,263,299],"median(95%":[257],"CI).":[258],"Normal":[259],"ranges":[260],"calculated":[262],"95%":[265],"CI":[266],"HC.":[268,445],"Median":[269],"age":[270],"[30(28,33)":[271],"years]":[272],"BMI":[274],"[23.8(22.9,29.0)":[275],"kg/m2]":[276],"similar":[278],"between":[279,366],"groups.":[280],"greater":[284,382,397],"MRMD":[286,312,328,341,356,432],"vs":[287,290,313,316,342,345],"HC":[288,314,343],"[7(3,13)":[289],"2(1,4),":[291],"p=0.005)":[292],"only,":[298],"expected.":[300],"In":[301],"phase,":[304,458],"median":[306,331],"level":[308],"higher":[310,339,424],"[86(40,148)":[315],"29(24,73)":[317],"pg/mL,":[318],"p=0.05]":[319],"frankly":[321],"elevated":[322,350,461],"6":[324],"9":[326,354],"(67%)":[327],"[0.8(0.4,2.2)":[344],"0.4":[346],"(0.3,0.8),":[347],"p=0.03]":[348],"4":[352],"(44%)":[355],"There":[358],"differences":[361],"steroid":[364],"groups":[367],"during":[368],"phase.":[371],"Higher":[372],"associated":[380],"(r=0.51,":[388],"p=0.01)":[389],"(r=0.54,":[393],"p=0.007)":[394],"(r=0.41,":[405],"p=0.05).":[406],"Conclusion:":[407],"Contrary":[408],"our":[410],"hypothesis,":[411],"we":[412],"found":[413],"steroids,":[418],"effects,":[422],"\u2013":[433,442],"who":[434],"experience":[435],"compared":[443],"This":[446],"suggests":[447],"increased":[449],"conversion":[450],"resulting":[459],"levels,":[463],"may":[464],"be":[465],"compensatory":[467],"response":[468],"some":[475],"Presentation":[479],"Date:":[480],"Friday,":[481],"June":[482],"16,":[483],"2023":[484]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2023-10-09T00:00:00"}