{"id":"https://openalex.org/W4387344801","doi":"https://doi.org/10.1111/odi.14754","title":"Salivary opiorphin levels in denture\u2010related traumatic ulcers","display_name":"Salivary opiorphin levels in denture\u2010related traumatic ulcers","publication_year":2023,"publication_date":"2023-10-04","ids":{"openalex":"https://openalex.org/W4387344801","doi":"https://doi.org/10.1111/odi.14754","pmid":"https://pubmed.ncbi.nlm.nih.gov/37793134"},"language":"en","primary_location":{"id":"doi:10.1111/odi.14754","doi":"https://doi.org/10.1111/odi.14754","is_oa":true,"landing_page_url":"https://doi.org/10.1111/odi.14754","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/odi.14754","source":{"id":"https://openalex.org/S144270092","display_name":"Oral Diseases","issn_l":"1354-523X","issn":["1354-523X","1601-0825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oral Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/odi.14754","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030017634","display_name":"Mahmut Serta\u00e7 \u00d6zdo\u011fan","orcid":"https://orcid.org/0000-0003-1312-8794","observed_orcids":["https://orcid.org/0000-0003-1312-8794"]},"institutions":[{"id":"https://openalex.org/I4210150808","display_name":"Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University","ror":"https://ror.org/05ryemn72","country_code":"TR","type":"education","lineage":["https://openalex.org/I4210150808"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Mahmut Sertac Ozdogan","raw_affiliation_strings":["Department of Prosthodontics, Faculty of Dentistry Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University  Ankara Turkiye"],"raw_orcid":"https://orcid.org/0000-0003-1312-8794","affiliations":[{"raw_affiliation_string":"Department of Prosthodontics, Faculty of Dentistry Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University  Ankara Turkiye","institution_ids":["https://openalex.org/I4210150808"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062534072","display_name":"Mustafa G\u00fcng\u00f6rm\u00fc\u015f","orcid":"https://orcid.org/0000-0001-8894-0467","observed_orcids":["https://orcid.org/0000-0001-8894-0467"]},"institutions":[{"id":"https://openalex.org/I4210150808","display_name":"Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University","ror":"https://ror.org/05ryemn72","country_code":"TR","type":"education","lineage":["https://openalex.org/I4210150808"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mustafa Gungormus","raw_affiliation_strings":["Central Research Laboratory Application and Research Center, Ankara Yildirim Beyazit University, Ankara, Turkiye","Department of Basic Sciences, Faculty of Dentistry Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University  Ankara Turkiye"],"raw_orcid":"https://orcid.org/0000-0001-8894-0467","affiliations":[{"raw_affiliation_string":"Central Research Laboratory Application and Research Center, Ankara Yildirim Beyazit University, Ankara, Turkiye","institution_ids":["https://openalex.org/I4210150808"]},{"raw_affiliation_string":"Department of Basic Sciences, Faculty of Dentistry Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University  Ankara Turkiye","institution_ids":["https://openalex.org/I4210150808"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5030017634"],"corresponding_institution_ids":["https://openalex.org/I4210150808"],"apc_list":{"value":4840,"currency":"USD","value_usd":4840},"apc_paid":null,"fwci":1.5048,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.81000692,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"30","issue":"5","first_page":"3136","last_page":"3141"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":0.25049999356269836,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":0.25049999356269836,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.21230000257492065,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.13930000364780426,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/opiorphin","display_name":"opiorphin","score":0.9380000233650208},{"id":"https://openalex.org/keywords/salivary-biomarkers","display_name":"salivary biomarkers","score":0.8930000066757202},{"id":"https://openalex.org/keywords/traumatic-oral-ulcer","display_name":"traumatic oral ulcer","score":0.671999990940094},{"id":"https://openalex.org/keywords/ill-fitting-dentures","display_name":"ill-fitting dentures","score":0.9779999852180481},{"id":"https://openalex.org/keywords/orofacial-pain","display_name":"orofacial pain","score":0.765999972820282},{"id":"https://openalex.org/keywords/denture-adjustment","display_name":"denture adjustment","score":0.781000018119812},{"id":"https://openalex.org/keywords/pain-relief","display_name":"analgesia","score":0.7929999828338623},{"id":"https://openalex.org/keywords/analgesic-peptides","display_name":"analgesic peptides","score":0.800000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8335363864898682},{"id":"https://openalex.org/C504460877","wikidata":"https://www.wikidata.org/wiki/Q155925","display_name":"Saliva","level":2,"score":0.812574565410614},{"id":"https://openalex.org/C2780062004","wikidata":"https://www.wikidata.org/wiki/Q143567","display_name":"Dentures","level":2,"score":0.711772620677948},{"id":"https://openalex.org/C14184104","wikidata":"https://www.wikidata.org/wiki/Q1362526","display_name":"Visual analogue scale","level":2,"score":0.5264984965324402},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.5199293494224548},{"id":"https://openalex.org/C2780820201","wikidata":"https://www.wikidata.org/wiki/Q173235","display_name":"Analgesic","level":2,"score":0.4481007754802704},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.31759077310562134},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27051037549972534}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003824","descriptor_name":"Denture, Complete","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005157","descriptor_name":"Facial Pain","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012463","descriptor_name":"Saliva","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012463","descriptor_name":"Saliva","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012471","descriptor_name":"Salivary Proteins and Peptides","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012471","descriptor_name":"Salivary Proteins and Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019226","descriptor_name":"Oral Ulcer","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D019226","descriptor_name":"Oral Ulcer","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/odi.14754","doi":"https://doi.org/10.1111/odi.14754","is_oa":true,"landing_page_url":"https://doi.org/10.1111/odi.14754","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/odi.14754","source":{"id":"https://openalex.org/S144270092","display_name":"Oral Diseases","issn_l":"1354-523X","issn":["1354-523X","1601-0825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oral Diseases","raw_type":"journal-article"},{"id":"pmid:37793134","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37793134","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oral diseases","raw_type":"Journal Article"},{"id":"pmh:5e3fd4da-6874-4aa3-80ca-03e117224479","doi":null,"is_oa":false,"landing_page_url":"https://avesis.aybu.edu.tr/publication/details/5e3fd4da-6874-4aa3-80ca-03e117224479/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055213","display_name":"AYBU AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1111/odi.14754","doi":"https://doi.org/10.1111/odi.14754","is_oa":true,"landing_page_url":"https://doi.org/10.1111/odi.14754","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/odi.14754","source":{"id":"https://openalex.org/S144270092","display_name":"Oral Diseases","issn_l":"1354-523X","issn":["1354-523X","1601-0825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oral Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387344801.pdf","grobid_xml":"https://content.openalex.org/works/W4387344801.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W35083005","https://openalex.org/W1505986655","https://openalex.org/W1526353445","https://openalex.org/W1983311071","https://openalex.org/W1985687426","https://openalex.org/W2049436397","https://openalex.org/W2070666673","https://openalex.org/W2072432944","https://openalex.org/W2087551428","https://openalex.org/W2090852459","https://openalex.org/W2111896482","https://openalex.org/W2127002115","https://openalex.org/W2131398998","https://openalex.org/W2139656462","https://openalex.org/W2143886428","https://openalex.org/W2168872016","https://openalex.org/W2550620860","https://openalex.org/W2561950974","https://openalex.org/W2583514134","https://openalex.org/W2772068217","https://openalex.org/W2782743668","https://openalex.org/W2904976470","https://openalex.org/W2921162026","https://openalex.org/W3030213507","https://openalex.org/W3109190233","https://openalex.org/W3213695962","https://openalex.org/W4291017786","https://openalex.org/W4318070559","https://openalex.org/W6631326560"],"related_works":["https://openalex.org/W2904976470","https://openalex.org/W3109190233","https://openalex.org/W4409366180","https://openalex.org/W3148291862","https://openalex.org/W4386856446","https://openalex.org/W7000304524","https://openalex.org/W2921690277","https://openalex.org/W2603325100","https://openalex.org/W7154747965","https://openalex.org/W3193581990"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Opiorphin":[1],"is":[2,58],"a":[3,10,28,79,101,194],"pentapeptide":[4],"secreted":[5],"in":[6,21,31,47,88,179,190,198],"saliva":[7,107,130],"and":[8,24,54,65,78,120,134,142,163,193],"has":[9,16],"strong":[11],"analgesic":[12],"effect.":[13],"Salivary":[14],"opiorphin":[15,45,67,131,157,176,199],"been":[17],"shown":[18],"to":[19,41,84,94],"increase":[20,178],"orofacial":[22],"pain":[23,29,32,63,82,99,119,180,191],"may":[25],"act":[26],"as":[27],"reliever":[30],"caused":[33,50],"by":[34,51],"denture-related":[35,183],"ulcers.":[36,185],"The":[37,128,171],"current":[38],"study":[39],"aimed":[40],"evaluate":[42],"the":[43,112,116,124,154,165,168,187],"salivary":[44,66,156,175],"levels":[46,64,177],"traumatic":[48,184],"ulcers":[49],"ill-fitting":[52,85],"dentures":[53,77,188],"demonstrate":[55],"whether":[56],"there":[57],"any":[59],"correlation":[60],"between":[61],"trauma-related":[62],"levels.":[68,200],"MATERIALS":[69],"AND":[70],"METHODS:":[71],"Twenty-two":[72],"individuals":[73],"with":[74,115,182],"new":[75],"full":[76],"complaint":[80,117],"of":[81,98,118,167],"due":[83],"were":[86,92,109,138],"included":[87],"this":[89],"study.":[90],"Patients":[91],"asked":[93],"rate":[95],"their":[96],"level":[97,132,158],"on":[100],"visual":[102],"analog":[103],"scale":[104],"(VAS).":[105],"Then,":[106],"specimens":[108],"collected":[110],"at":[111],"first":[113],"visit":[114],"7":[121],"days":[122],"following":[123],"denture":[125,136],"adjustment.":[126],"RESULTS:":[127],"average":[129],"before":[133,162],"after":[135,164],"adjustment":[137,166],"19.29":[139],"\u00b1":[140,144],"5.44":[141],"15.78":[143],"3.95":[145],"ng/mL,":[146],"respectively.":[147],"A":[148],"dependent":[149],"(paired)":[150],"t-test":[151],"determined":[152],"that":[153,174],"mean":[155],"differed":[159],"statistically":[160,195],"significantly":[161],"dentures.":[169],"CONCLUSIONS:":[170],"findings":[172],"show":[173],"associated":[181],"Adjusting":[186],"resulted":[189],"relief":[192],"significant":[196],"reduction":[197]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-10-05T00:00:00"}