{"id":"https://openalex.org/W4387326709","doi":"https://doi.org/10.1080/14647273.2023.2251678","title":"Tissue engineering studies in male infertility disorder","display_name":"Tissue engineering studies in male infertility disorder","publication_year":2023,"publication_date":"2023-10-04","ids":{"openalex":"https://openalex.org/W4387326709","doi":"https://doi.org/10.1080/14647273.2023.2251678","pmid":"https://pubmed.ncbi.nlm.nih.gov/37791451"},"language":"en","primary_location":{"id":"doi:10.1080/14647273.2023.2251678","doi":"https://doi.org/10.1080/14647273.2023.2251678","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14647273.2023.2251678","pdf_url":null,"source":{"id":"https://openalex.org/S51346222","display_name":"Human Fertility","issn_l":"1464-7273","issn":["1464-7273","1742-8149"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Fertility","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Javad Jokar","orcid":"https://orcid.org/0000-0003-4888-4119","observed_orcids":["https://orcid.org/0000-0003-4888-4119"]},"institutions":[{"id":"https://openalex.org/I4210161235","display_name":"Fasa University of Medical Sciences","ror":"https://ror.org/05bh0zx16","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210161235"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Javad Jokar","raw_affiliation_strings":["Department of Tissue Engineering, Faculty of Medicine, Fasa University of Medical Science, Fasa, Iran"],"raw_orcid":"https://orcid.org/0000-0003-4888-4119","affiliations":[{"raw_affiliation_string":"Department of Tissue Engineering, Faculty of Medicine, Fasa University of Medical Science, Fasa, Iran","institution_ids":["https://openalex.org/I4210161235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077007859","display_name":"Hussein T. Abdulabbas","orcid":"https://orcid.org/0000-0002-2157-8392","observed_orcids":["https://orcid.org/0000-0002-2157-8392"]},"institutions":[{"id":"https://openalex.org/I166455938","display_name":"University of Babylon","ror":"https://ror.org/0170edc15","country_code":"IQ","type":"education","lineage":["https://openalex.org/I166455938"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Hussein T. Abdulabbas","raw_affiliation_strings":["Department of Biology, University of Babylon, Hillah, Iraq"],"raw_orcid":"https://orcid.org/0000-0002-2157-8392","affiliations":[{"raw_affiliation_string":"Department of Biology, University of Babylon, Hillah, Iraq","institution_ids":["https://openalex.org/I166455938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003881436","display_name":"Hiva Alipanah","orcid":"https://orcid.org/0000-0002-0598-0912","observed_orcids":["https://orcid.org/0000-0002-0598-0912"]},"institutions":[{"id":"https://openalex.org/I4210161235","display_name":"Fasa University of Medical Sciences","ror":"https://ror.org/05bh0zx16","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210161235"]},{"id":"https://openalex.org/I4400600978","display_name":"Fasa University","ror":"https://ror.org/03a77cf20","country_code":"IR","type":"education","lineage":["https://openalex.org/I4400600978"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Hiva Alipanah","raw_affiliation_strings":["Department of Physiology, School of Medicine, Fasa University of Medical Science, Fasa, Iran"],"raw_orcid":"https://orcid.org/0000-0002-0598-0912","affiliations":[{"raw_affiliation_string":"Department of Physiology, School of Medicine, Fasa University of Medical Science, Fasa, Iran","institution_ids":["https://openalex.org/I4210161235","https://openalex.org/I4400600978"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024465731","display_name":"Abdolmajid Ghasemian","orcid":"https://orcid.org/0000-0002-1243-6341","observed_orcids":["https://orcid.org/0000-0002-1243-6341"]},"institutions":[{"id":"https://openalex.org/I4210161235","display_name":"Fasa University of Medical Sciences","ror":"https://ror.org/05bh0zx16","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210161235"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Abdolmajid Ghasemian","raw_affiliation_strings":["Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran"],"raw_orcid":"https://orcid.org/0000-0002-1243-6341","affiliations":[{"raw_affiliation_string":"Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran","institution_ids":["https://openalex.org/I4210161235"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jafar Ai","orcid":"https://orcid.org/0000-0002-6549-481X","observed_orcids":["https://orcid.org/0000-0002-6549-481X"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Jafar Ai","raw_affiliation_strings":["Tissue Engineering and Applied Cell Sciences Department, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":"https://orcid.org/0000-0002-6549-481X","affiliations":[{"raw_affiliation_string":"Tissue Engineering and Applied Cell Sciences Department, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034108373","display_name":"Niloofar Rahimian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161235","display_name":"Fasa University of Medical Sciences","ror":"https://ror.org/05bh0zx16","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210161235"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Niloofar Rahimian","raw_affiliation_strings":["Department of Biotechnology, Faculty of Medicine, Fasa University of Medical Sciences, Fasa, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Faculty of Medicine, Fasa University of Medical Sciences, Fasa, Iran","institution_ids":["https://openalex.org/I4210161235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070334209","display_name":"Elham Mohammadisoleimani","orcid":"https://orcid.org/0000-0002-3950-3102","observed_orcids":["https://orcid.org/0000-0002-3950-3102"]},"institutions":[{"id":"https://openalex.org/I4210161235","display_name":"Fasa University of Medical Sciences","ror":"https://ror.org/05bh0zx16","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210161235"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Elham Mohammadisoleimani","raw_affiliation_strings":["Department of Biotechnology, Faculty of Medicine, Fasa University of Medical Sciences, Fasa, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Faculty of Medicine, Fasa University of Medical Sciences, Fasa, Iran","institution_ids":["https://openalex.org/I4210161235"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011975686","display_name":"Sohrab Najafipour","orcid":"https://orcid.org/0000-0001-5224-5876","observed_orcids":["https://orcid.org/0000-0001-5224-5876"]},"institutions":[{"id":"https://openalex.org/I4210161235","display_name":"Fasa University of Medical Sciences","ror":"https://ror.org/05bh0zx16","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210161235"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Sohrab Najafipour","raw_affiliation_strings":["Department of Microbiology, Faculty of Medicine, Fasa University of Medical Sciences, Fasa, Iran"],"raw_orcid":"https://orcid.org/0000-0001-5224-5876","affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine, Fasa University of Medical Sciences, Fasa, Iran","institution_ids":["https://openalex.org/I4210161235"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5011975686"],"corresponding_institution_ids":["https://openalex.org/I4210161235"],"apc_list":null,"apc_paid":null,"fwci":0.0669,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.10658915,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"26","issue":"6","first_page":"1617","last_page":"1635"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.017400000244379044,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/male-infertility","display_name":"male infertility","score":0.9929999709129333},{"id":"https://openalex.org/keywords/tissue-engineering","display_name":"tissue engineering","score":0.9079999923706055},{"id":"https://openalex.org/keywords/in-vitro-spermatogenesis","display_name":"in vitro spermatogenesis","score":0.9829999804496765},{"id":"https://openalex.org/keywords/fertility-preservation","display_name":"fertility preservation","score":0.7910000085830688},{"id":"https://openalex.org/keywords/3d-cell-culture","display_name":"3D cell culture","score":0.7599999904632568},{"id":"https://openalex.org/keywords/seminiferous-tubules","display_name":"seminiferous tubules","score":0.7889999747276306},{"id":"https://openalex.org/keywords/growth-factors","display_name":"growth factors","score":0.6480000019073486},{"id":"https://openalex.org/keywords/biomaterial-scaffolds","display_name":"biomaterial scaffolds","score":0.7900000214576721},{"id":"https://openalex.org/keywords/stem-cells","display_name":"stem cells","score":0.5950000286102295},{"id":"https://openalex.org/keywords/germ-cells","display_name":"germ cells","score":0.45500001311302185},{"id":"https://openalex.org/keywords/microenvironment","display_name":"microenvironment","score":0.5070000290870667}],"concepts":[{"id":"https://openalex.org/C7876069","wikidata":"https://www.wikidata.org/wiki/Q14873666","display_name":"Paracrine signalling","level":3,"score":0.7549139261245728},{"id":"https://openalex.org/C123765429","wikidata":"https://www.wikidata.org/wiki/Q36961","display_name":"Spermatogenesis","level":2,"score":0.602592945098877},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.5899662375450134},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.5180644989013672},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5075210332870483},{"id":"https://openalex.org/C2777338322","wikidata":"https://www.wikidata.org/wiki/Q280156","display_name":"Male infertility","level":4,"score":0.49951601028442383},{"id":"https://openalex.org/C2777904497","wikidata":"https://www.wikidata.org/wiki/Q5445580","display_name":"Fertility preservation","level":4,"score":0.45380619168281555},{"id":"https://openalex.org/C2994278967","wikidata":"https://www.wikidata.org/wiki/Q7314318","display_name":"Reproductive technology","level":4,"score":0.4320264160633087},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.42473191022872925},{"id":"https://openalex.org/C518429986","wikidata":"https://www.wikidata.org/wiki/Q964401","display_name":"Fertility","level":3,"score":0.41957154870033264},{"id":"https://openalex.org/C2779122487","wikidata":"https://www.wikidata.org/wiki/Q281579","display_name":"Germ cell","level":3,"score":0.41095295548439026},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.35361674427986145},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.32454872131347656},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2401232123374939},{"id":"https://openalex.org/C179933525","wikidata":"https://www.wikidata.org/wiki/Q1144664","display_name":"Cryopreservation","level":3,"score":0.21105024218559265},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.17418769001960754},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.13191187381744385},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.09242391586303711},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.08943244814872742},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06253194808959961},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007248","descriptor_name":"Infertility, Male","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012671","descriptor_name":"Seminiferous Tubules","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013091","descriptor_name":"Spermatogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013737","descriptor_name":"Testis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1080/14647273.2023.2251678","doi":"https://doi.org/10.1080/14647273.2023.2251678","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14647273.2023.2251678","pdf_url":null,"source":{"id":"https://openalex.org/S51346222","display_name":"Human Fertility","issn_l":"1464-7273","issn":["1464-7273","1742-8149"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Fertility","raw_type":"journal-article"},{"id":"pmid:37791451","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37791451","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human fertility (Cambridge, England)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":149,"referenced_works":["https://openalex.org/W1516316082","https://openalex.org/W1650607266","https://openalex.org/W1723001059","https://openalex.org/W1787536492","https://openalex.org/W1943418900","https://openalex.org/W1963555441","https://openalex.org/W1969845288","https://openalex.org/W1970138808","https://openalex.org/W1972337090","https://openalex.org/W1972812055","https://openalex.org/W1973839563","https://openalex.org/W1976582271","https://openalex.org/W1977109906","https://openalex.org/W1979665070","https://openalex.org/W1992049575","https://openalex.org/W1994937751","https://openalex.org/W1997919787","https://openalex.org/W2001454442","https://openalex.org/W2002120333","https://openalex.org/W2002226709","https://openalex.org/W2003004843","https://openalex.org/W2005077411","https://openalex.org/W2006044949","https://openalex.org/W2014657344","https://openalex.org/W2016789158","https://openalex.org/W2018508671","https://openalex.org/W2021019932","https://openalex.org/W2029711503","https://openalex.org/W2038113907","https://openalex.org/W2043851579","https://openalex.org/W2048646278","https://openalex.org/W2051738856","https://openalex.org/W2057322816","https://openalex.org/W2057582738","https://openalex.org/W2060482440","https://openalex.org/W2062853358","https://openalex.org/W2068818788","https://openalex.org/W2073738799","https://openalex.org/W2087372058","https://openalex.org/W2091028885","https://openalex.org/W2094085358","https://openalex.org/W2095918275","https://openalex.org/W2099930565","https://openalex.org/W2102681710","https://openalex.org/W2105425843","https://openalex.org/W2105997887","https://openalex.org/W2107542456","https://openalex.org/W2109665403","https://openalex.org/W2110797273","https://openalex.org/W2110804359","https://openalex.org/W2126844356","https://openalex.org/W2128181658","https://openalex.org/W2128308512","https://openalex.org/W2136896400","https://openalex.org/W2144813080","https://openalex.org/W2145437958","https://openalex.org/W2146321865","https://openalex.org/W2149540190","https://openalex.org/W2150749999","https://openalex.org/W2151145524","https://openalex.org/W2152507092","https://openalex.org/W2157770461","https://openalex.org/W2159546274","https://openalex.org/W2163078895","https://openalex.org/W2163368922","https://openalex.org/W2165976940","https://openalex.org/W2166187009","https://openalex.org/W2167776880","https://openalex.org/W2168003742","https://openalex.org/W2183777750","https://openalex.org/W2254986166","https://openalex.org/W2269373901","https://openalex.org/W2312488853","https://openalex.org/W2317303028","https://openalex.org/W2322395793","https://openalex.org/W2331628193","https://openalex.org/W2344895179","https://openalex.org/W2369003249","https://openalex.org/W2402275391","https://openalex.org/W2467363155","https://openalex.org/W2494708821","https://openalex.org/W2507761967","https://openalex.org/W2545319799","https://openalex.org/W2561750927","https://openalex.org/W2570104463","https://openalex.org/W2575297515","https://openalex.org/W2580908592","https://openalex.org/W2603245558","https://openalex.org/W2604728425","https://openalex.org/W2606250005","https://openalex.org/W2616395902","https://openalex.org/W2741302213","https://openalex.org/W2748078521","https://openalex.org/W2753202871","https://openalex.org/W2762686401","https://openalex.org/W2766343935","https://openalex.org/W2782693871","https://openalex.org/W2800386423","https://openalex.org/W2800798819","https://openalex.org/W2811526028","https://openalex.org/W2883409661","https://openalex.org/W2887754886","https://openalex.org/W2888492074","https://openalex.org/W2893806018","https://openalex.org/W2894683556","https://openalex.org/W2896805781","https://openalex.org/W2896813244","https://openalex.org/W2897864335","https://openalex.org/W2905628722","https://openalex.org/W2925822959","https://openalex.org/W2936229295","https://openalex.org/W2937307265","https://openalex.org/W2944020803","https://openalex.org/W2947016882","https://openalex.org/W2950447581","https://openalex.org/W2951783464","https://openalex.org/W2955383222","https://openalex.org/W2961305922","https://openalex.org/W2962752620","https://openalex.org/W2964723225","https://openalex.org/W2971186544","https://openalex.org/W2979536060","https://openalex.org/W2980160205","https://openalex.org/W2980839753","https://openalex.org/W2989735823","https://openalex.org/W2996000106","https://openalex.org/W2996987780","https://openalex.org/W3002359018","https://openalex.org/W3003581684","https://openalex.org/W3005926143","https://openalex.org/W3005959097","https://openalex.org/W3008145964","https://openalex.org/W3009475248","https://openalex.org/W3009681692","https://openalex.org/W3011526621","https://openalex.org/W3014297870","https://openalex.org/W3062517739","https://openalex.org/W3083628935","https://openalex.org/W3132242418","https://openalex.org/W3161117055","https://openalex.org/W3161426911","https://openalex.org/W3172048719","https://openalex.org/W4211208521","https://openalex.org/W4230240787","https://openalex.org/W4250155542","https://openalex.org/W4280546876","https://openalex.org/W4306653029","https://openalex.org/W4310179639","https://openalex.org/W4313362508"],"related_works":["https://openalex.org/W4283397555","https://openalex.org/W3217296584","https://openalex.org/W4406687138","https://openalex.org/W7214233607","https://openalex.org/W3210973761","https://openalex.org/W3002359018","https://openalex.org/W4404889942","https://openalex.org/W4406948333","https://openalex.org/W2973838438","https://openalex.org/W3005926143"],"abstract_inverted_index":{"Infertility":[0],"is":[1,9,19,31,157,165,192],"an":[2],"important":[3],"issue":[4],"among":[5],"couples":[6],"worldwide":[7],"which":[8],"caused":[10],"by":[11],"a":[12,20,56,60,95,124,154,177],"variety":[13],"of":[14,24,87,101,111,114,120,123,127,146,153,187,204,221],"complex":[15],"diseases.":[16],"Male":[17],"infertility":[18],"problem":[21],"in":[22,45,52,70,117,130,150,159,206,218],"7%":[23],"all":[25],"men.":[26],"In":[27],"vitro":[28],"spermatogenesis":[29,161],"(IVS)":[30],"the":[32,109,112,118,144,151,170,202,205,219],"experimental":[33],"approach":[34],"that":[35,142],"has":[36,76],"been":[37,136],"developed":[38,77],"for":[39,64,99,180,194],"mimicking":[40],"seminiferous":[41,208],"tubules-like":[42],"functional":[43,88],"structures":[44,172],"vitro.":[46,71],"Currently,":[47],"various":[48],"researchers":[49],"are":[50],"interested":[51],"finding":[53],"and":[54,182,196,216],"developing":[55],"microenvironmental":[57],"condition":[58],"or":[59,229],"bioartificial":[61],"testis":[62],"applied":[63],"fertility":[65,83],"restoration":[66,100],"via":[67],"gamete":[68],"production":[69],"The":[72,185],"tissue":[73],"engineering":[74],"(TE)":[75],"new":[78],"approaches":[79],"to":[80,168,175,200,224],"treat":[81],"male":[82,89,102],"preservation":[84],"through":[85],"development":[86],"germ":[90],"cells.":[91,184],"This":[92,210],"makes":[93],"TE":[94,222],"possible":[96,167,193],"future":[97],"strategy":[98],"fertility.":[103],"Although":[104],"3D":[105,131],"culture":[106,132,226],"systems":[107,133],"supply":[108],"perception":[110],"effect":[113],"cellular":[115],"interactions":[116],"process":[119],"spermatogenesis,":[121],"formation":[122],"native":[125],"gradient":[126],"autocrine/paracrine":[128],"factors":[129],"have":[134],"not":[135],"considered.":[137],"These":[138],"results":[139],"collectively":[140],"suggest":[141],"maintaining":[143],"microenvironment":[145,203],"testicular":[147,171],"cells":[148,189],"even":[149],"form":[152],"3D-culture":[155],"system":[156],"crucial":[158],"achieving":[160],"ex":[162],"vivo.":[163],"It":[164],"also":[166],"engineer":[169],"using":[173],"biomaterials":[174],"provide":[176],"supporting":[178],"scaffold":[179],"somatic":[181],"stem":[183],"insemination":[186],"these":[188],"with":[190,233],"GFs":[191],"temporally":[195],"spatially":[197],"adjusted":[198],"release":[199],"mimic":[201],"situ":[207],"epithelium.":[209],"review":[211],"focuses":[212],"on":[213,227],"recent":[214],"studies":[215],"advances":[217],"application":[220],"strategies":[223],"cell-tissue":[225],"synthetic":[228],"natural":[230],"scaffolds":[231],"supplemented":[232],"growth":[234],"factors.":[235]},"counts_by_year":[{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-10-05T00:00:00"}
