{"id":"https://openalex.org/W4387297976","doi":"https://doi.org/10.1177/10998004231203257","title":"Fatigue, Toll-Like Receptor 4, and Pro-Inflammatory Cytokines in Adults With Subarachnoid Hemorrhage: A 6-Month Longitudinal Study","display_name":"Fatigue, Toll-Like Receptor 4, and Pro-Inflammatory Cytokines in Adults With Subarachnoid Hemorrhage: A 6-Month Longitudinal Study","publication_year":2023,"publication_date":"2023-10-03","ids":{"openalex":"https://openalex.org/W4387297976","doi":"https://doi.org/10.1177/10998004231203257","pmid":"https://pubmed.ncbi.nlm.nih.gov/37788710","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13632675"},"language":"en","primary_location":{"id":"doi:10.1177/10998004231203257","doi":"https://doi.org/10.1177/10998004231203257","is_oa":false,"landing_page_url":"https://doi.org/10.1177/10998004231203257","pdf_url":null,"source":{"id":"https://openalex.org/S144954103","display_name":"Biological Research For Nursing","issn_l":"1099-8004","issn":["1099-8004","1552-4175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Research For Nursing","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13632675/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043556054","display_name":"Eeeseung Byun","orcid":"https://orcid.org/0000-0002-8917-7093","observed_orcids":["https://orcid.org/0000-0002-8917-7093"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eeeseung Byun","raw_affiliation_strings":["Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, WA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8917-7093","affiliations":[{"raw_affiliation_string":"Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047598978","display_name":"Susan M. McCurry","orcid":"https://orcid.org/0000-0001-8624-3772","observed_orcids":["https://orcid.org/0000-0001-8624-3772"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan M. McCurry","raw_affiliation_strings":["Department of Child, Family and Population Health Nursing, University of Washington, Seattle, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Child, Family and Population Health Nursing, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102760159","display_name":"Suyoung Kwon","orcid":"https://orcid.org/0000-0003-3045-7055","observed_orcids":["https://orcid.org/0000-0003-3045-7055"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suyoung Kwon","raw_affiliation_strings":["Department of Child, Family and Population Health Nursing, University of Washington, Seattle, WA, USA"],"raw_orcid":"https://orcid.org/0000-0003-3045-7055","affiliations":[{"raw_affiliation_string":"Department of Child, Family and Population Health Nursing, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012526414","display_name":"Chi-Shan Tsai","orcid":"https://orcid.org/0000-0002-1639-5014","observed_orcids":["https://orcid.org/0000-0002-1639-5014"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chi-shan Tsai","raw_affiliation_strings":["Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049725662","display_name":"Jeehye Jun","orcid":"https://orcid.org/0000-0003-1353-7125","observed_orcids":["https://orcid.org/0000-0003-1353-7125"]},"institutions":[{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jeehye Jun","raw_affiliation_strings":["Red Cross College of Nursing, Chung-Ang University, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0003-1353-7125","affiliations":[{"raw_affiliation_string":"Red Cross College of Nursing, Chung-Ang University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I67900169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017464120","display_name":"Theo K. Bammler","orcid":"https://orcid.org/0000-0001-8325-2825","observed_orcids":["https://orcid.org/0000-0001-8325-2825"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theo K. Bammler","raw_affiliation_strings":["Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017463095","display_name":"Kyra J. Becker","orcid":"https://orcid.org/0000-0002-8310-4846","observed_orcids":["https://orcid.org/0000-0002-8310-4846"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyra J. Becker","raw_affiliation_strings":["Department of Neurology, University of Washington, Seattle, WA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083974295","display_name":"Hilaire J. Thompson","orcid":"https://orcid.org/0000-0002-5472-478X","observed_orcids":["https://orcid.org/0000-0002-5472-478X"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hilaire J. Thompson","raw_affiliation_strings":["Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, WA, USA"],"raw_orcid":"https://orcid.org/0000-0002-5472-478X","affiliations":[{"raw_affiliation_string":"Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5043556054"],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":0.1557,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.1951539,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"26","issue":"2","first_page":"192","last_page":"201"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":0.6499000191688538,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":0.6499000191688538,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.04839999973773956,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":0.044599998742341995,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/subarachnoid-hemorrhage","display_name":"subarachnoid hemorrhage","score":0.9390000104904175},{"id":"https://openalex.org/keywords/post-traumatic-fatigue","display_name":"post-traumatic fatigue","score":0.8259999752044678},{"id":"https://openalex.org/keywords/tlr4","display_name":"TLR4","score":0.9610000252723694},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.7680000066757202},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8669999837875366},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9539999961853027},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":1.0},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6520000100135803},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7120000123977661}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7597466111183167},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.6341009140014648},{"id":"https://openalex.org/C2777736543","wikidata":"https://www.wikidata.org/wiki/Q693442","display_name":"Subarachnoid hemorrhage","level":2,"score":0.591023325920105},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5680180191993713},{"id":"https://openalex.org/C11988809","wikidata":"https://www.wikidata.org/wiki/Q412889","display_name":"Interleukin 6","level":3,"score":0.5585303902626038},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5196641683578491},{"id":"https://openalex.org/C2776070231","wikidata":"https://www.wikidata.org/wiki/Q14914098","display_name":"TLR4","level":3,"score":0.5038227438926697},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4839208722114563},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3264901638031006},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005221","descriptor_name":"Fatigue","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013345","descriptor_name":"Subarachnoid Hemorrhage","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051197","descriptor_name":"Toll-Like Receptor 4","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051197","descriptor_name":"Toll-Like Receptor 4","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1177/10998004231203257","doi":"https://doi.org/10.1177/10998004231203257","is_oa":false,"landing_page_url":"https://doi.org/10.1177/10998004231203257","pdf_url":null,"source":{"id":"https://openalex.org/S144954103","display_name":"Biological Research For Nursing","issn_l":"1099-8004","issn":["1099-8004","1552-4175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Research For Nursing","raw_type":"journal-article"},{"id":"pmid:37788710","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37788710","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological research for nursing","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13632675","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13632675/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biol Res Nurs","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:13632675","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13632675/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biol Res Nurs","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2222461341","display_name":"Asian Resource Centers for Minority Aging Research (RCMAR)","funder_award_id":"P30AG059304","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G3686473658","display_name":"Institute of Translational Health Sciences","funder_award_id":"UL1TR000423","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6259888759","display_name":"Mechanisms of Symptoms in Subarachnoid Hemorrhage: Sleep Disturbance, Fatigue and Impaired Cognition","funder_award_id":"K23NR017404","funder_id":"https://openalex.org/F4320337353","funder_display_name":"National Institute of Nursing Research"},{"id":"https://openalex.org/G8006595022","display_name":"Center for Innovation in Sleep Self-Management (CISSM)","funder_award_id":"P30NR016585","funder_id":"https://openalex.org/F4320337353","funder_display_name":"National Institute of Nursing Research"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337353","display_name":"National Institute of Nursing Research","ror":"https://ror.org/01y3zfr79"},{"id":"https://openalex.org/F6782126199","display_name":"Population Health Initiative, University of Washington","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1677400045","https://openalex.org/W1897578981","https://openalex.org/W1970399077","https://openalex.org/W1970503368","https://openalex.org/W1973717649","https://openalex.org/W2013273080","https://openalex.org/W2072120077","https://openalex.org/W2120321156","https://openalex.org/W2131574149","https://openalex.org/W2134013805","https://openalex.org/W2135412225","https://openalex.org/W2151487996","https://openalex.org/W2160233610","https://openalex.org/W2162420979","https://openalex.org/W2166281097","https://openalex.org/W2169380093","https://openalex.org/W2215814671","https://openalex.org/W2303635956","https://openalex.org/W2403366498","https://openalex.org/W2521625787","https://openalex.org/W2554390311","https://openalex.org/W2603428110","https://openalex.org/W2605835540","https://openalex.org/W2725552686","https://openalex.org/W2737166034","https://openalex.org/W2760855096","https://openalex.org/W2922705656","https://openalex.org/W3035430205","https://openalex.org/W3052552270","https://openalex.org/W3092237838","https://openalex.org/W3129375397","https://openalex.org/W4211137064","https://openalex.org/W4220888294","https://openalex.org/W4293544707"],"related_works":["https://openalex.org/W4411965891","https://openalex.org/W7155548750","https://openalex.org/W3052552270","https://openalex.org/W4410501952","https://openalex.org/W1970503368","https://openalex.org/W4387308579","https://openalex.org/W2344052782","https://openalex.org/W3208878588","https://openalex.org/W4214828983","https://openalex.org/W3090705660"],"abstract_inverted_index":{"BACKGROUND:":[0],"Fatigue":[1,109,115,178],"is":[2],"prevalent":[3],"in":[4,180,236],"subarachnoid":[5],"hemorrhage":[6],"(SAH)":[7],"survivors.":[8,88,238],"Biological":[9],"mechanisms":[10],"underlying":[11],"fatigue":[12,36,171,199,235],"post-SAH":[13,105,204],"are":[14],"not":[15],"clear.":[16],"Inflammation":[17,228],"may":[18],"contribute":[19],"to":[20,28,106,128,230],"the":[21,30,38,113,130,173,188,194,201,223,232],"development":[22,233],"of":[23,52,63,85,167,187,198,234],"fatigue.":[24,164],"This":[25],"study":[26,80],"aimed":[27],"examine":[29],"associations":[31,131],"between":[32,132],"inflammatory":[33],"markers":[34],"and":[35,49,60,72,97,99,102,120,137,139,143,153,156,162,191,215,218],"during":[37,172,193,200,222],"first":[39,174],"6":[40,103,121,144,175,195,202,224],"months":[41,104,176,203,225],"post-SAH.":[42,177,226],"Specific":[43],"biomarkers":[44],"examined":[45],"included":[46],"both":[47],"early":[48,133],"concurrent":[50,140,163],"expression":[51,148,151],"Toll-Like":[53],"Receptor":[54],"4":[55],"(TLR4)":[56],"messenger":[57],"RNA":[58],"(mRNA)":[59],"plasma":[61,158,210,220],"concentrations":[62,159,211,221],"pro-inflammatory":[64],"cytokines,":[65],"Tumor":[66],"Necrosis":[67],"Factor-alpha":[68],"(TNF-\u03b1),":[69],"Interleukin":[70],"(IL)1\u03b2,":[71],"IL6.":[73],"METHODS:":[74],"We":[75,89],"conducted":[76],"a":[77,82],"6-month":[78],"longitudinal":[79],"with":[81,207],"convenience":[83],"sample":[84],"43":[86],"SAH":[87,168,181,237],"collected":[90],"blood":[91],"samples":[92],"on":[93,212],"days":[94],"2,":[95,100,118,135],"3,":[96,101,119,136,142],"7":[98,214],"assess":[107],"biomarkers.":[108],"was":[110,205],"assessed":[111],"by":[112],"PROMIS":[114],"Scale":[116],"at":[117],"months.":[122,196],"Linear":[123],"mixed":[124],"models":[125],"were":[126,183],"used":[127],"test":[129],"(days":[134],"7)":[138],"(2,":[141],"months)":[145],"TLR4":[146],"mRNA":[147],"(TagMan":[149],"gene":[150],"assays)":[152,161],"TNF-\u03b1,":[154],"IL1\u03b2,":[155,216],"IL6":[157],"(multiplex":[160],"RESULTS:":[165],"28%":[166],"survivors":[169,182],"experienced":[170],"levels":[179],"higher":[184,208],"than":[185],"those":[186],"U.S.":[189],"population":[190],"consistent":[192],"Experience":[197],"associated":[206],"IL1\u03b2":[209],"day":[213],"IL6,":[217],"TNF-\u03b1":[219],"CONCLUSION:":[227],"appears":[229],"underlie":[231]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-10-04T00:00:00"}