{"id":"https://openalex.org/W4387297331","doi":"https://doi.org/10.1016/j.foodhyd.2023.109328","title":"Encapsulation of probiotics with poly-\u03b3-glutamic acid alters gut microbiota and short-chain fatty acid content by maintaining cell viability in the gastrointestinal tract","display_name":"Encapsulation of probiotics with poly-\u03b3-glutamic acid alters gut microbiota and short-chain fatty acid content by maintaining cell viability in the gastrointestinal tract","publication_year":2023,"publication_date":"2023-10-03","ids":{"openalex":"https://openalex.org/W4387297331","doi":"https://doi.org/10.1016/j.foodhyd.2023.109328"},"language":"en","primary_location":{"id":"doi:10.1016/j.foodhyd.2023.109328","doi":"https://doi.org/10.1016/j.foodhyd.2023.109328","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.foodhyd.2023.109328","pdf_url":null,"source":{"id":"https://openalex.org/S168584722","display_name":"Food Hydrocolloids","issn_l":"0268-005X","issn":["0268-005X","1873-7137"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Hydrocolloids","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.foodhyd.2023.109328","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074451763","display_name":"Won Je Jang","orcid":"https://orcid.org/0000-0002-2372-8366","observed_orcids":["https://orcid.org/0000-0002-2372-8366"]},"institutions":[{"id":"https://openalex.org/I204974687","display_name":"Dong-Eui University","ror":"https://ror.org/059g69b28","country_code":"KR","type":"education","lineage":["https://openalex.org/I204974687"]},{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Won Je Jang","raw_affiliation_strings":["Biopharmaceutical Engineering Major, Division of Applied Bioengineering, Dong-Eui University, Busan, 47340, South Korea","Department of Biotechnology, Pukyong National University, Busan, 48513, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biopharmaceutical Engineering Major, Division of Applied Bioengineering, Dong-Eui University, Busan, 47340, South Korea","institution_ids":["https://openalex.org/I204974687"]},{"raw_affiliation_string":"Department of Biotechnology, Pukyong National University, Busan, 48513, South Korea","institution_ids":["https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038957189","display_name":"Dong Nyoung Oh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dong Nyoung Oh","raw_affiliation_strings":["Department of Biotechnology, Pukyong National University, Busan, 48513, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Pukyong National University, Busan, 48513, South Korea","institution_ids":["https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058031911","display_name":"Da Yeong Kim","orcid":"https://orcid.org/0000-0001-7489-9539","observed_orcids":["https://orcid.org/0000-0001-7489-9539"]},"institutions":[{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Da Yeong Kim","raw_affiliation_strings":["Department of Biotechnology, Pukyong National University, Busan, 48513, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Pukyong National University, Busan, 48513, South Korea","institution_ids":["https://openalex.org/I8991828"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110780036","display_name":"Eun Ji Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Eun Ji Lee","raw_affiliation_strings":["Department of Biotechnology, Pukyong National University, Busan, 48513, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Pukyong National University, Busan, 48513, South Korea","institution_ids":["https://openalex.org/I8991828"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069028509","display_name":"Jong Min Lee","orcid":"https://orcid.org/0000-0002-5523-4627","observed_orcids":["https://orcid.org/0000-0002-5523-4627"]},"institutions":[{"id":"https://openalex.org/I8991828","display_name":"Pukyong National University","ror":"https://ror.org/0433kqc49","country_code":"KR","type":"education","lineage":["https://openalex.org/I8991828"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jong Min Lee","raw_affiliation_strings":["Department of Biotechnology, Pukyong National University, Busan, 48513, South Korea"],"raw_orcid":"https://orcid.org/0000-0002-5523-4627","affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Pukyong National University, Busan, 48513, South Korea","institution_ids":["https://openalex.org/I8991828"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5069028509"],"corresponding_institution_ids":["https://openalex.org/I8991828"],"apc_list":{"value":4650,"currency":"USD","value_usd":4650},"apc_paid":{"value":4650,"currency":"USD","value_usd":4650},"fwci":2.9596,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.90327833,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"147","issue":null,"first_page":"109328","last_page":"109328"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12048","display_name":"Microencapsulation and Drying Processes","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/probiotic-microencapsulation","display_name":"probiotic encapsulation","score":0.859000027179718},{"id":"https://openalex.org/keywords/poly-gamma-glutamic-acid","display_name":"poly-\u03b3-glutamic acid","score":0.9990000128746033},{"id":"https://openalex.org/keywords/probiotic-viability","display_name":"probiotic viability","score":0.9359999895095825},{"id":"https://openalex.org/keywords/simulated-gastric-fluid","display_name":"simulated gastric fluid","score":0.8240000009536743},{"id":"https://openalex.org/keywords/gastrointestinal-digestion","display_name":"gastrointestinal digestion","score":0.8769999742507935},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.8830000162124634},{"id":"https://openalex.org/keywords/short-chain-fatty-acids","display_name":"short-chain fatty acids","score":0.9779999852180481},{"id":"https://openalex.org/keywords/propionic-acid","display_name":"propionic acid","score":0.9739999771118164},{"id":"https://openalex.org/keywords/lactobacillus","display_name":"Lactobacillus","score":0.890999972820282},{"id":"https://openalex.org/keywords/limosilactobacillus-reuteri","display_name":"Lactobacillus reuteri","score":0.9959999918937683},{"id":"https://openalex.org/keywords/bile-acid-resistance","display_name":"bile acid resistance","score":0.4729999899864197}],"concepts":[{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.752206563949585},{"id":"https://openalex.org/C2775898472","wikidata":"https://www.wikidata.org/wiki/Q597078","display_name":"Lactobacillus reuteri","level":4,"score":0.7008040547370911},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.6755439043045044},{"id":"https://openalex.org/C2780512811","wikidata":"https://www.wikidata.org/wiki/Q11829360","display_name":"Gastrointestinal tract","level":2,"score":0.576062023639679},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.5046037435531616},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4911660850048065},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.48624005913734436},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.44208624958992004},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.440976083278656},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4387272000312805},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3891964554786682},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38274961709976196},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.34347033500671387},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2946167588233948},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.11506009101867676},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.foodhyd.2023.109328","doi":"https://doi.org/10.1016/j.foodhyd.2023.109328","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.foodhyd.2023.109328","pdf_url":null,"source":{"id":"https://openalex.org/S168584722","display_name":"Food Hydrocolloids","issn_l":"0268-005X","issn":["0268-005X","1873-7137"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Hydrocolloids","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.foodhyd.2023.109328","doi":"https://doi.org/10.1016/j.foodhyd.2023.109328","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.foodhyd.2023.109328","pdf_url":null,"source":{"id":"https://openalex.org/S168584722","display_name":"Food Hydrocolloids","issn_l":"0268-005X","issn":["0268-005X","1873-7137"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Hydrocolloids","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8070402902","display_name":null,"funder_award_id":"2022R1C1C1004586","funder_id":"https://openalex.org/F4320322030","funder_display_name":"Ministry of Science, ICT and Future Planning"}],"funders":[{"id":"https://openalex.org/F4320322030","display_name":"Ministry of Science, ICT and Future Planning","ror":"https://ror.org/032e49973"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W155910638","https://openalex.org/W331774268","https://openalex.org/W1993644792","https://openalex.org/W2014444288","https://openalex.org/W2019610847","https://openalex.org/W2020310633","https://openalex.org/W2022261243","https://openalex.org/W2030970409","https://openalex.org/W2032834143","https://openalex.org/W2035417981","https://openalex.org/W2044907720","https://openalex.org/W2055767862","https://openalex.org/W2056658113","https://openalex.org/W2071840922","https://openalex.org/W2076500913","https://openalex.org/W2083311703","https://openalex.org/W2092339106","https://openalex.org/W2107855220","https://openalex.org/W2116444522","https://openalex.org/W2127577188","https://openalex.org/W2137174290","https://openalex.org/W2149443281","https://openalex.org/W2153132096","https://openalex.org/W2557742390","https://openalex.org/W2614141842","https://openalex.org/W2775080294","https://openalex.org/W2800107914","https://openalex.org/W2809410346","https://openalex.org/W2906970179","https://openalex.org/W2941517901","https://openalex.org/W2987589871","https://openalex.org/W3003912482","https://openalex.org/W3012176958","https://openalex.org/W3035269803","https://openalex.org/W3097105994","https://openalex.org/W3173712960","https://openalex.org/W3212124679","https://openalex.org/W4289794126","https://openalex.org/W4304842842","https://openalex.org/W6606402359","https://openalex.org/W6611445069","https://openalex.org/W6763525281"],"related_works":["https://openalex.org/W2947848472","https://openalex.org/W2044907720","https://openalex.org/W2568074953","https://openalex.org/W4388665797","https://openalex.org/W3033516741","https://openalex.org/W4381273810","https://openalex.org/W4386609461","https://openalex.org/W2325172599","https://openalex.org/W2185460535","https://openalex.org/W3199625353"],"abstract_inverted_index":{"The":[0,38,67,194],"viability":[1,33,68,100,203],"of":[2,25,36,41,69,82,96,101,137,149,204,210],"most":[3],"probiotics":[4,71,205],"is":[5],"generally":[6],"reduced":[7,78],"by":[8],"gastric":[9,55],"and":[10,34,51,53,62,116,157,223],"bile":[11],"acids":[12,166],"during":[13],"passage":[14],"through":[15],"the":[16,23,32,99,113,147,150,154,163,185,191,202,207,211,220],"host's":[17],"gastrointestinal":[18,109,208],"tract.":[19],"Therefore,":[20],"we":[21],"investigated":[22],"effect":[24,40],"encapsulation":[26,43,92,119,145,200],"with":[27,129],"poly-\u03b3-glutamic":[28],"acid":[29,160],"(\u03b3-PGA)":[30],"on":[31,217],"function":[35],"probiotics.":[37],"protective":[39],"\u03b3-PGA":[42,46,91,199],"at":[44,93],"different":[45],"concentrations":[47,174],"(0.25,":[48],"0.5,":[49],"0.75,":[50],"1.0%)":[52],"simulated":[54],"juice":[56],"(SGJ)":[57],"exposure":[58,83],"times":[59],"(1,":[60],"2,":[61],"3":[63,80],"h)":[64],"was":[65,72],"assessed.":[66],"all":[70,102],"either":[73],"completely":[74],"lost":[75],"or":[76],"significantly":[77,182],"within":[79],"h":[81],"to":[84,141,180],"SGJ":[85],"under":[86],"non-encapsulation":[87,192],"conditions.":[88],"In":[89,105,131,169],"contrast,":[90],"a":[94,122],"concentration":[95],"0.25\u20131.00%":[97],"maintained":[98],"SGJ-exposed":[103],"strains.":[104],"an":[106],"in":[107,121,153,175,184,190,206,219],"vitro":[108],"digestion":[110],"experiment":[111],"simulating":[112],"oral,":[114],"gastric,":[115],"duodenal":[117],"phases,":[118],"resulted":[120],"higher":[123,183],"survival":[124],"rate":[125],"than":[126,189],"that":[127,144,198],"associated":[128],"non-encapsulation.":[130],"vivo":[132],"experiments":[133],"involving":[134],"oral":[135],"administration":[136],"encapsulated":[138,186],"Limosilactobacillus":[139],"reuteri":[140],"mice":[142],"showed":[143],"increased":[146,158],"abundance":[148],"genus":[151],"Lactobacillus":[152],"gut":[155,221],"microbiota":[156,222],"propionic":[159],"content":[161],"among":[162],"short-chain":[164],"fatty":[165],"(SCFAs)":[167],"analyzed.":[168],"addition,":[170],"live":[171],"probiotic":[172],"cell":[173],"mouse":[176],"feces":[177],"were":[178],"found":[179],"be":[181],"probiotic-fed":[187],"group":[188],"group.":[193],"present":[195],"findings":[196],"demonstrate":[197],"maintains":[201],"tract":[209],"host,":[212],"while":[213],"providing":[214],"beneficial":[215],"effects":[216],"changes":[218],"SCFA":[224],"content.":[225]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2023-10-04T00:00:00"}