{"id":"https://openalex.org/W4387215502","doi":"https://doi.org/10.1186/s12935-023-03070-x","title":"Prediction model for hyperprogressive disease in patients with advanced solid tumors received immune-checkpoint inhibitors: a pan-cancer study","display_name":"Prediction model for hyperprogressive disease in patients with advanced solid tumors received immune-checkpoint inhibitors: a pan-cancer study","publication_year":2023,"publication_date":"2023-09-30","ids":{"openalex":"https://openalex.org/W4387215502","doi":"https://doi.org/10.1186/s12935-023-03070-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/37777758","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10543870"},"language":"en","primary_location":{"id":"doi:10.1186/s12935-023-03070-x","doi":"https://doi.org/10.1186/s12935-023-03070-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12935-023-03070-x","pdf_url":"https://cancerci.biomedcentral.com/counter/pdf/10.1186/s12935-023-03070-x","source":{"id":"https://openalex.org/S130214813","display_name":"Cancer Cell International","issn_l":"1475-2867","issn":["1475-2867"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Cell International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://cancerci.biomedcentral.com/counter/pdf/10.1186/s12935-023-03070-x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077991377","display_name":"Yaping Long","orcid":"https://orcid.org/0000-0002-2706-3656","observed_orcids":["https://orcid.org/0000-0002-2706-3656"]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaping Long","raw_affiliation_strings":["School of Medicine, Nankai University, 94 Weijin Road, Nankai, Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, Nankai University, 94 Weijin Road, Nankai, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113282151","display_name":"Wenyu Yang","orcid":"https://orcid.org/0009-0004-6048-2328","observed_orcids":["https://orcid.org/0009-0004-6048-2328"]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenyu Yang","raw_affiliation_strings":["School of Medicine, Nankai University, 94 Weijin Road, Nankai, Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, Nankai University, 94 Weijin Road, Nankai, Tianjin, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019302956","display_name":"Yibing Bai","orcid":"https://orcid.org/0000-0002-2944-5367","observed_orcids":["https://orcid.org/0000-0002-2944-5367"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yibing Bai","raw_affiliation_strings":["Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China","PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China","institution_ids":["https://openalex.org/I2802939634"]},{"raw_affiliation_string":"PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060960928","display_name":"Haitao Tao","orcid":"https://orcid.org/0009-0001-1295-8692","observed_orcids":["https://orcid.org/0009-0001-1295-8692"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haitao Tao","raw_affiliation_strings":["Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100403393","display_name":"Fan Zhang","orcid":"https://orcid.org/0000-0001-6798-2422","observed_orcids":["https://orcid.org/0000-0001-6798-2422"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fan Zhang","raw_affiliation_strings":["Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100651062","display_name":"Lijie Wang","orcid":"https://orcid.org/0000-0003-4914-9781","observed_orcids":["https://orcid.org/0000-0003-4914-9781"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lijie Wang","raw_affiliation_strings":["Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043791066","display_name":"Bo Yeun Yang","orcid":"https://orcid.org/0000-0002-8989-9387","observed_orcids":["https://orcid.org/0000-0002-8989-9387"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bo Yang","raw_affiliation_strings":["Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022715798","display_name":"Di Huang","orcid":"https://orcid.org/0000-0001-7304-4889","observed_orcids":["https://orcid.org/0000-0001-7304-4889"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Di Huang","raw_affiliation_strings":["Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiao Han","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiao Han","raw_affiliation_strings":["Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China. hanxiaoplagh@126.com","Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China. hanxiaoplagh@126.com","institution_ids":["https://openalex.org/I2802939634"]},{"raw_affiliation_string":"Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042174429","display_name":"Yi Hu","orcid":"https://orcid.org/0000-0001-9319-5692","observed_orcids":["https://orcid.org/0000-0001-9319-5692"]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]},{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yi Hu","raw_affiliation_strings":["Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China. huyi301zlxb@sina.com.cn","PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China. huyi301zlxb@sina.com.cn","School of Medicine, Nankai University, 94 Weijin Road, Nankai, Tianjin, China. huyi301zlxb@sina.com.cn","Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China. huyi301zlxb@sina.com.cn","institution_ids":["https://openalex.org/I2802939634"]},{"raw_affiliation_string":"PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, 100853, People's Republic of China. huyi301zlxb@sina.com.cn","institution_ids":["https://openalex.org/I2802939634"]},{"raw_affiliation_string":"School of Medicine, Nankai University, 94 Weijin Road, Nankai, Tianjin, China. huyi301zlxb@sina.com.cn","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"Department of Medical Oncology, Department of Medical Oncology, Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, 8 Dongdajie Road, Fengtai District, Beijing, 100071, China","institution_ids":["https://openalex.org/I2802939634"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5042174429"],"corresponding_institution_ids":["https://openalex.org/I205237279","https://openalex.org/I2802939634"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":2890,"currency":"USD","value_usd":2890},"fwci":0.4858,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.62734184,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"23","issue":"1","first_page":"224","last_page":"224"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperprogressive-disease","display_name":"hyperprogressive disease","score":0.9779999852180481},{"id":"https://openalex.org/keywords/immune-checkpoint-inhibitors","display_name":"immune checkpoint inhibitors","score":0.9679999947547913},{"id":"https://openalex.org/keywords/advanced-solid-tumors","display_name":"advanced solid tumors","score":0.8190000057220459},{"id":"https://openalex.org/keywords/predictive-model","display_name":"prediction model","score":0.6980000138282776},{"id":"https://openalex.org/keywords/nomogram","display_name":"nomogram","score":0.800000011920929},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.8460000157356262},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.7760000228881836},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.972000002861023},{"id":"https://openalex.org/keywords/lymph-node-metastasis","display_name":"lymph node metastasis","score":0.9649999737739563},{"id":"https://openalex.org/keywords/pancreatic-metastasis","display_name":"pancreatic metastasis","score":0.9800000190734863},{"id":"https://openalex.org/keywords/angiogenesis-inhibition","display_name":"angiogenesis inhibition","score":0.781000018119812},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.6079999804496765},{"id":"https://openalex.org/keywords/immunotherapy-response","display_name":"immunotherapy response","score":0.5130000114440918}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8958156108856201},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6136404275894165},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6074680685997009},{"id":"https://openalex.org/C34626388","wikidata":"https://www.wikidata.org/wiki/Q721129","display_name":"Nomogram","level":2,"score":0.6032038927078247},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.535140872001648},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.48911792039871216},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.4871096611022949},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.47025975584983826},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.46812453866004944},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.44612565636634827},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.42440056800842285},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1186/s12935-023-03070-x","doi":"https://doi.org/10.1186/s12935-023-03070-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12935-023-03070-x","pdf_url":"https://cancerci.biomedcentral.com/counter/pdf/10.1186/s12935-023-03070-x","source":{"id":"https://openalex.org/S130214813","display_name":"Cancer Cell International","issn_l":"1475-2867","issn":["1475-2867"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Cell International","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10543870","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10543870","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10543870/pdf/12935_2023_Article_3070.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Cell Int","raw_type":"Text"},{"id":"pmid:37777758","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37777758","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer cell international","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:a0f89b33c7774d32a4eefae12a9e9db5","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a0f89b33c7774d32a4eefae12a9e9db5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cancer Cell International, Vol 23, Iss 1, Pp 1-15 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12935-023-03070-x","doi":"https://doi.org/10.1186/s12935-023-03070-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12935-023-03070-x","pdf_url":"https://cancerci.biomedcentral.com/counter/pdf/10.1186/s12935-023-03070-x","source":{"id":"https://openalex.org/S130214813","display_name":"Cancer Cell International","issn_l":"1475-2867","issn":["1475-2867"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Cell International","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G8473158629","display_name":null,"funder_award_id":"81902917","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320329926","display_name":"National Health Commission of the People's Republic of China","ror":"https://ror.org/04bdenw41"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387215502.pdf","grobid_xml":"https://content.openalex.org/works/W4387215502.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W2554618897","https://openalex.org/W2605497049","https://openalex.org/W2891951654","https://openalex.org/W2935797142","https://openalex.org/W2949640269","https://openalex.org/W3005152261","https://openalex.org/W3006976689","https://openalex.org/W3009008277","https://openalex.org/W3022341722","https://openalex.org/W3024437374","https://openalex.org/W3033097010","https://openalex.org/W3033353648","https://openalex.org/W3038098692","https://openalex.org/W3048614517","https://openalex.org/W3049075450","https://openalex.org/W3081262846","https://openalex.org/W3092062217","https://openalex.org/W3098349066","https://openalex.org/W3110726556","https://openalex.org/W3137983189","https://openalex.org/W3151754693","https://openalex.org/W3212084686","https://openalex.org/W4200009282","https://openalex.org/W4223645659","https://openalex.org/W4224046477","https://openalex.org/W4229447115","https://openalex.org/W4280516985","https://openalex.org/W4289544318","https://openalex.org/W4297458750","https://openalex.org/W4315705344"],"related_works":["https://openalex.org/W6902236234","https://openalex.org/W3029879800","https://openalex.org/W4402194006","https://openalex.org/W4387966338","https://openalex.org/W3154616442","https://openalex.org/W4220718359","https://openalex.org/W3048614517","https://openalex.org/W3110988687","https://openalex.org/W4281783537","https://openalex.org/W4311141310"],"abstract_inverted_index":{"BACKGROUND:":[0],"Hyper":[1],"progressive":[2],"disease":[3],"(HPD)":[4],"describes":[5],"the":[6,35,63,70,132,144,185,201,209,215],"phenomenon":[7,23],"that":[8,37,143,159],"patients":[9,55,98,109,122,149,230,250],"can't":[10],"benefit":[11],"from":[12,105],"immunotherapy":[13,25],"but":[14,26],"cause":[15],"rapid":[16],"tumor":[17,54,71],"progression.":[18],"HPD":[19,40,79,126,148,186,226,241],"is":[20,206],"a":[21,43,89,195,222,233],"particular":[22],"in":[24,62,168,208,214],"lacks":[27],"prediction":[28],"methods.":[29],"Our":[30],"study":[31,224],"aims":[32],"to":[33,247],"screen":[34],"factors":[36,137],"may":[38],"forecast":[39],"and":[41,76,88,116,173,200,231,236,251],"provide":[42],"predictive":[44,90],"model":[45,93,238],"for":[46,127,225,239],"risky":[47,249],"stratifying.":[48],"METHODS:":[49],"We":[50,219],"retrospectively":[51],"reviewed":[52],"advanced-stage":[53],"who":[56,110],"received":[57,111],"immune":[58],"checkpoint":[59],"inhibitors":[60],"(ICI)":[61],"General":[64],"PLA":[65],"Hospital.":[66],"Subsequently,":[67],"we":[68,157,193],"calculated":[69],"growth":[72],"kinetics":[73],"ratio":[74],"(TGKr)":[75],"identified":[77,124],"typical":[78],"patients.":[80,155],"Differences":[81],"analysis":[82,141],"of":[83,147],"clinical":[84,145],"characteristics":[85],"was":[86,94,150],"performed,":[87],"binary":[91],"classification":[92],"constructed.":[95],"RESULTS:":[96],"867":[97],"with":[99,176,184],"complete":[100],"image":[101],"information":[102],"were":[103,123,138,181],"screened":[104],"more":[106],"than":[107,153],"3000":[108],"ICI":[112],"between":[113],"January":[114,117],"2015":[115],"2020.":[118],"Among":[119],"them,":[120],"36":[121],"as":[125],"TGKr":[128],">":[129],"2.":[130],"After":[131],"propensity":[133],"score":[134],"matched,":[135],"confounding":[136],"limited.":[139],"Survival":[140],"revealed":[142],"outcome":[146],"significantly":[151],"worse":[152],"non-HPD":[154],"Besides,":[156],"found":[158],"Body":[160],"Mass":[161],"Index":[162],"(BMI),":[163],"anemia,":[164],"lymph":[165],"node":[166],"metastasis":[167],"non-draining":[169],"areas,":[170],"pancreatic":[171],"metastasis,":[172],"whether":[174],"combined":[175],"anti-angiogenesis":[177],"or":[178],"chemotherapy":[179],"therapy":[180],"closely":[182],"connected":[183],"incidence.":[187],"Based":[188],"on":[189,228],"these":[190],"risk":[191],"factors,":[192],"constructed":[194,232],"visualised":[196],"predicted":[197],"nomogram":[198],"model,":[199],"Area":[202],"Under":[203],"Curve":[204],"(AUC)":[205],"0.850":[207],"train":[210],"dataset,":[211],"whereas":[212],"0.812":[213],"test":[216],"dataset.":[217],"CONCLUSION:":[218],"carried":[220],"out":[221],"retrospective":[223],"based":[227],"real-world":[229],"clinically":[234],"feasible":[235],"practical":[237],"predicting":[240],"incidence,":[242],"which":[243],"could":[244],"help":[245],"oncologists":[246],"stratify":[248],"select":[252],"treatment":[253],"strategies.":[254]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2023-10-01T00:00:00"}