{"id":"https://openalex.org/W4387207680","doi":"https://doi.org/10.1016/j.celrep.2023.113187","title":"Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine","display_name":"Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine","publication_year":2023,"publication_date":"2023-09-29","ids":{"openalex":"https://openalex.org/W4387207680","doi":"https://doi.org/10.1016/j.celrep.2023.113187","pmid":"https://pubmed.ncbi.nlm.nih.gov/37777968","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10753961"},"language":"en","primary_location":{"id":"doi:10.1016/j.celrep.2023.113187","doi":"https://doi.org/10.1016/j.celrep.2023.113187","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.celrep.2023.113187","pdf_url":null,"source":{"id":"https://openalex.org/S169236886","display_name":"Cell Reports","issn_l":"2211-1247","issn":["2211-1247","2639-1856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.celrep.2023.113187","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048308048","display_name":"Devin Rocks","orcid":"https://orcid.org/0000-0002-3192-0219","observed_orcids":["https://orcid.org/0000-0002-3192-0219"]},"institutions":[{"id":"https://openalex.org/I164389053","display_name":"Fordham University","ror":"https://ror.org/03qnxaf80","country_code":"US","type":"education","lineage":["https://openalex.org/I164389053"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Devin Rocks","raw_affiliation_strings":["Department of Biological Sciences, Fordham University, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Fordham University, Bronx, NY, USA","institution_ids":["https://openalex.org/I164389053"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052594738","display_name":"Ivana Jari\u0107","orcid":"https://orcid.org/0000-0002-8818-2974","observed_orcids":["https://orcid.org/0000-0002-8818-2974"]},"institutions":[{"id":"https://openalex.org/I164389053","display_name":"Fordham University","ror":"https://ror.org/03qnxaf80","country_code":"US","type":"education","lineage":["https://openalex.org/I164389053"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ivana Jaric","raw_affiliation_strings":["Department of Biological Sciences, Fordham University, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Fordham University, Bronx, NY, USA","institution_ids":["https://openalex.org/I164389053"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067381939","display_name":"Fabio Bellia","orcid":"https://orcid.org/0000-0002-8443-6084","observed_orcids":["https://orcid.org/0000-0002-8443-6084"]},"institutions":[{"id":"https://openalex.org/I164389053","display_name":"Fordham University","ror":"https://ror.org/03qnxaf80","country_code":"US","type":"education","lineage":["https://openalex.org/I164389053"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fabio Bellia","raw_affiliation_strings":["Department of Biological Sciences, Fordham University, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Fordham University, Bronx, NY, USA","institution_ids":["https://openalex.org/I164389053"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066911367","display_name":"Heining Cham","orcid":"https://orcid.org/0000-0002-2933-056X","observed_orcids":["https://orcid.org/0000-0002-2933-056X"]},"institutions":[{"id":"https://openalex.org/I164389053","display_name":"Fordham University","ror":"https://ror.org/03qnxaf80","country_code":"US","type":"education","lineage":["https://openalex.org/I164389053"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heining Cham","raw_affiliation_strings":["Department of Psychology, Fordham University, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, Fordham University, Bronx, NY, USA","institution_ids":["https://openalex.org/I164389053"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048839844","display_name":"John M. Greally","orcid":"https://orcid.org/0000-0001-6069-7960","observed_orcids":["https://orcid.org/0000-0001-6069-7960"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John M. Greally","raw_affiliation_strings":["Center for Epigenomics, Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Epigenomics, Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040370543","display_name":"Masako Suzuki","orcid":"https://orcid.org/0000-0003-0605-9225","observed_orcids":["https://orcid.org/0000-0003-0605-9225"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Masako Suzuki","raw_affiliation_strings":["Center for Epigenomics, Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA; Department of Nutrition, Texas A&M University, College Station, TX, USA","Center for Epigenomics, Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA","Department of Nutrition, Texas A&M University, College Station, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Epigenomics, Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA; Department of Nutrition, Texas A&M University, College Station, TX, USA","institution_ids":["https://openalex.org/I129975664","https://openalex.org/I91045830"]},{"raw_affiliation_string":"Center for Epigenomics, Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Nutrition, Texas A&M University, College Station, TX, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089796357","display_name":"Marija Kundakovi\u0107","orcid":"https://orcid.org/0000-0002-6734-4217","observed_orcids":["https://orcid.org/0000-0002-6734-4217"]},"institutions":[{"id":"https://openalex.org/I164389053","display_name":"Fordham University","ror":"https://ror.org/03qnxaf80","country_code":"US","type":"education","lineage":["https://openalex.org/I164389053"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marija Kundakovic","raw_affiliation_strings":["Department of Biological Sciences, Fordham University, Bronx, NY, USA. Electronic address: mkundakovic@fordham.edu","Department of Biological Sciences, Fordham University, Bronx, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-6734-4217","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Fordham University, Bronx, NY, USA. Electronic address: mkundakovic@fordham.edu","institution_ids":["https://openalex.org/I164389053"]},{"raw_affiliation_string":"Department of Biological Sciences, Fordham University, Bronx, NY, USA","institution_ids":["https://openalex.org/I164389053"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5089796357"],"corresponding_institution_ids":["https://openalex.org/I164389053"],"apc_list":{"value":5460,"currency":"USD","value_usd":5460},"apc_paid":{"value":5460,"currency":"USD","value_usd":5460},"fwci":1.5725,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.82494257,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"42","issue":"10","first_page":"113187","last_page":"113187"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/early-life-stress","display_name":"early life stress","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ovarian-hormones","display_name":"ovarian hormones","score":0.9729999899864197},{"id":"https://openalex.org/keywords/estrogen","display_name":"estrogen","score":0.8009999990463257},{"id":"https://openalex.org/keywords/cocaine-dependence","display_name":"cocaine dependence","score":0.593999981880188},{"id":"https://openalex.org/keywords/nucleus-accumbens","display_name":"nucleus accumbens","score":0.9589999914169312},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8009999990463257},{"id":"https://openalex.org/keywords/x-chromosome-inactivation","display_name":"X chromosome inactivation","score":0.8180000185966492},{"id":"https://openalex.org/keywords/deltafosb","display_name":"\u0394FosB","score":0.8220000267028809},{"id":"https://openalex.org/keywords/chromatin-accessibility","display_name":"chromatin accessibility","score":0.8360000252723694},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.7540000081062317},{"id":"https://openalex.org/keywords/estrogen-withdrawal","display_name":"estrogen withdrawal","score":0.7239999771118164},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.7699999809265137},{"id":"https://openalex.org/keywords/women-s-vulnerability","display_name":"women's vulnerability","score":0.5519999861717224}],"concepts":[{"id":"https://openalex.org/C2776552330","wikidata":"https://www.wikidata.org/wiki/Q1476178","display_name":"Nucleus accumbens","level":3,"score":0.8808432817459106},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.6096305847167969},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.5944268703460693},{"id":"https://openalex.org/C48856860","wikidata":"https://www.wikidata.org/wiki/Q12029","display_name":"Addiction","level":2,"score":0.5224632024765015},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5183907151222229},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.4596303403377533},{"id":"https://openalex.org/C167227067","wikidata":"https://www.wikidata.org/wiki/Q5113739","display_name":"Chromatin remodeling","level":4,"score":0.44180235266685486},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4346201717853546},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.42310789227485657},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4019264578819275},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38330018520355225},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3710358142852783},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24720162153244019},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.20601847767829895},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16048920154571533}],"mesh":[{"descriptor_ui":"D000076783","descriptor_name":"Adverse Childhood Experiences","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003042","descriptor_name":"Cocaine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009714","descriptor_name":"Nucleus Accumbens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.celrep.2023.113187","doi":"https://doi.org/10.1016/j.celrep.2023.113187","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.celrep.2023.113187","pdf_url":null,"source":{"id":"https://openalex.org/S169236886","display_name":"Cell Reports","issn_l":"2211-1247","issn":["2211-1247","2639-1856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports","raw_type":"journal-article"},{"id":"doi:10.1101/2023.04.14.536984","doi":"https://doi.org/10.1101/2023.04.14.536984","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1101/2023.04.14.536984","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2023/04/15/2023.04.14.536984.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:37777968","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37777968","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10753961","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10753961","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10753961/pdf/nihms-1936794.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cell Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:b6e296708a1a4b089f80e461674c8161","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b6e296708a1a4b089f80e461674c8161","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cell Reports, Vol 42, Iss 10, Pp 113187- (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.celrep.2023.113187","doi":"https://doi.org/10.1016/j.celrep.2023.113187","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.celrep.2023.113187","pdf_url":null,"source":{"id":"https://openalex.org/S169236886","display_name":"Cell Reports","issn_l":"2211-1247","issn":["2211-1247","2639-1856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6474947825","display_name":"UNDERSTANDING CELLULAR AND TRANSCRIPTIONAL REGULATORY CHANGES IN HUMAN AGING","funder_award_id":"R01AG057422","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G7886363927","display_name":"IMPACT OF PRENATAL VITAMIN A DEFICIENCY ON CELL FATE ALTERATIONS IN ADULT AIRWAY HYPERRESPONSIVENESS","funder_award_id":"R01HL145302","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000910446","display_name":"Epigenetic regulation of brain and behavior by the estrous cycle","funder_award_id":"R01MH123523","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320306147","display_name":"Brain and Behavior Research Foundation","ror":"https://ror.org/03a63f080"},{"id":"https://openalex.org/F4320311440","display_name":"National Alliance for Research on Schizophrenia and Depression","ror":"https://ror.org/03a63f080"},{"id":"https://openalex.org/F4320311590","display_name":"Fordham University","ror":"https://ror.org/03qnxaf80"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332522","display_name":"Albert Einstein College of Medicine, Yeshiva University","ror":"https://ror.org/045x93337"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":118,"referenced_works":["https://openalex.org/W1487599137","https://openalex.org/W1959245327","https://openalex.org/W1964374986","https://openalex.org/W1968179768","https://openalex.org/W1977419289","https://openalex.org/W1979956204","https://openalex.org/W1981459575","https://openalex.org/W1983069416","https://openalex.org/W1991223384","https://openalex.org/W2000696407","https://openalex.org/W2004847334","https://openalex.org/W2014677321","https://openalex.org/W2015556634","https://openalex.org/W2029087061","https://openalex.org/W2029262422","https://openalex.org/W2031435056","https://openalex.org/W2035616108","https://openalex.org/W2040909468","https://openalex.org/W2042372462","https://openalex.org/W2042714786","https://openalex.org/W2049672698","https://openalex.org/W2051824629","https://openalex.org/W2054545874","https://openalex.org/W2057607875","https://openalex.org/W2067762272","https://openalex.org/W2070019933","https://openalex.org/W2073198325","https://openalex.org/W2073997424","https://openalex.org/W2075527287","https://openalex.org/W2076732852","https://openalex.org/W2077231388","https://openalex.org/W2077706363","https://openalex.org/W2078160165","https://openalex.org/W2080585999","https://openalex.org/W2081427205","https://openalex.org/W2083263207","https://openalex.org/W2088450404","https://openalex.org/W2097948046","https://openalex.org/W2099082142","https://openalex.org/W2103252476","https://openalex.org/W2115155925","https://openalex.org/W2117757143","https://openalex.org/W2118812779","https://openalex.org/W2123884188","https://openalex.org/W2130410032","https://openalex.org/W2131306683","https://openalex.org/W2135302954","https://openalex.org/W2135810615","https://openalex.org/W2136482257","https://openalex.org/W2137720632","https://openalex.org/W2142790764","https://openalex.org/W2145087065","https://openalex.org/W2149627698","https://openalex.org/W2150557642","https://openalex.org/W2154182432","https://openalex.org/W2156322627","https://openalex.org/W2158034397","https://openalex.org/W2158995449","https://openalex.org/W2159675211","https://openalex.org/W2161579926","https://openalex.org/W2165155762","https://openalex.org/W2166162210","https://openalex.org/W2166372248","https://openalex.org/W2166542841","https://openalex.org/W2169456326","https://openalex.org/W2169691228","https://openalex.org/W2179438025","https://openalex.org/W2255270868","https://openalex.org/W2293676523","https://openalex.org/W2426968778","https://openalex.org/W2509465044","https://openalex.org/W2520003619","https://openalex.org/W2551050667","https://openalex.org/W2570893979","https://openalex.org/W2765114110","https://openalex.org/W2776119327","https://openalex.org/W2794480084","https://openalex.org/W2806359197","https://openalex.org/W2807788357","https://openalex.org/W2808013179","https://openalex.org/W2809748547","https://openalex.org/W2900962132","https://openalex.org/W2922368534","https://openalex.org/W2922422632","https://openalex.org/W2923723239","https://openalex.org/W2931032935","https://openalex.org/W2944545583","https://openalex.org/W2950464315","https://openalex.org/W2952704221","https://openalex.org/W2953042895","https://openalex.org/W2955094575","https://openalex.org/W2984655624","https://openalex.org/W2986023816","https://openalex.org/W3026180445","https://openalex.org/W3037887196","https://openalex.org/W3045571735","https://openalex.org/W3046413177","https://openalex.org/W3081054913","https://openalex.org/W3090072122","https://openalex.org/W3090105988","https://openalex.org/W3108552772","https://openalex.org/W3127579217","https://openalex.org/W3129944553","https://openalex.org/W3130115660","https://openalex.org/W3138546537","https://openalex.org/W3139250185","https://openalex.org/W3150976406","https://openalex.org/W3164227705","https://openalex.org/W3216328166","https://openalex.org/W4200114973","https://openalex.org/W4205804453","https://openalex.org/W4281491285","https://openalex.org/W4282923728","https://openalex.org/W4282980827","https://openalex.org/W4313479633","https://openalex.org/W4316171380","https://openalex.org/W4319991435","https://openalex.org/W4394666350"],"related_works":["https://openalex.org/W2776119327","https://openalex.org/W2085514332","https://openalex.org/W2910594574","https://openalex.org/W2019694318","https://openalex.org/W6892219067","https://openalex.org/W4213240119","https://openalex.org/W2999876364","https://openalex.org/W2079915628","https://openalex.org/W2333470575","https://openalex.org/W4311769681"],"abstract_inverted_index":{"Early-life":[0],"stress":[1,56],"and":[2,32,45,57,88,107,118],"ovarian":[3],"hormones":[4],"contribute":[5],"to":[6,10,35,67,94,144],"increased":[7],"female":[8],"vulnerability":[9],"cocaine":[11,69,86,95,134,152],"addiction.":[12,89],"Here,":[13],"we":[14],"reveal":[15],"molecular":[16,142],"substrates":[17],"in":[18,50,62,84,136],"the":[19,22,59,76,126],"reward":[20],"area,":[21],"nucleus":[23],"accumbens,":[24],"through":[25],"which":[26],"these":[27],"female-specific":[28],"factors":[29],"affect":[30],"immediate":[31],"conditioning":[33,52,135],"responses":[34,53],"cocaine.":[36],"We":[37,110],"find":[38,111],"shared":[39],"involvement":[40],"of":[41,78,120,129,147],"X":[42,122],"chromosome":[43,123],"inactivation-related":[44],"estrogen":[46,114],"signaling-related":[47],"gene":[48],"regulation":[49],"enhanced":[51],"following":[54],"early-life":[55,116],"during":[58],"low-estrogenic":[60],"state":[61,132],"females.":[63,137],"Low-estrogenic":[64],"females":[65,92],"respond":[66,93],"acute":[68],"by":[70,96],"opening":[71],"neuronal":[72,149],"chromatin":[73,98,106],"enriched":[74],"for":[75,103],"sites":[77],"\u0394FosB,":[79],"a":[80,101,130,141],"transcription":[81],"factor":[82],"implicated":[83],"chronic":[85],"response":[87],"Conversely,":[90],"high-estrogenic":[91,131],"preferential":[97],"closing,":[99],"providing":[100],"mechanism":[102],"limiting":[104],"cocaine-driven":[105],"synaptic":[108],"plasticity.":[109],"that":[112],"physiological":[113],"withdrawal,":[115],"stress,":[117],"absence":[119],"one":[121],"all":[124],"nullify":[125],"protective":[127],"effect":[128],"on":[133],"Our":[138],"findings":[139],"offer":[140],"framework":[143],"enable":[145],"understanding":[146],"sex-specific":[148],"mechanisms":[150],"underlying":[151],"use":[153],"disorder.":[154]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-09-30T00:00:00"}
