{"id":"https://openalex.org/W4387166757","doi":"https://doi.org/10.1038/s41598-023-43574-0","title":"BBD optimized antioxidants of Crotalaria candicans and its nanoconjugates, exert potent in vivo anti-biofilm effects against MRSA","display_name":"BBD optimized antioxidants of Crotalaria candicans and its nanoconjugates, exert potent in vivo anti-biofilm effects against MRSA","publication_year":2023,"publication_date":"2023-09-29","ids":{"openalex":"https://openalex.org/W4387166757","doi":"https://doi.org/10.1038/s41598-023-43574-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/37775527","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10541877"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-023-43574-0","doi":"https://doi.org/10.1038/s41598-023-43574-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-023-43574-0","pdf_url":"https://www.nature.com/articles/s41598-023-43574-0.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-023-43574-0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006946942","display_name":"Ramya M. Subramani","orcid":"https://orcid.org/0000-0001-9231-8902","observed_orcids":["https://orcid.org/0000-0001-9231-8902"]},"institutions":[{"id":"https://openalex.org/I932239252","display_name":"SASTRA University","ror":"https://ror.org/032jk8892","country_code":"IN","type":"education","lineage":["https://openalex.org/I932239252"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ramya M. Subramani","raw_affiliation_strings":["Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India","institution_ids":["https://openalex.org/I932239252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051376637","display_name":"Robert Lotha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I932239252","display_name":"SASTRA University","ror":"https://ror.org/032jk8892","country_code":"IN","type":"education","lineage":["https://openalex.org/I932239252"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Robert Lotha","raw_affiliation_strings":["Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India","institution_ids":["https://openalex.org/I932239252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074210651","display_name":"Bhanuvalli R. Shamprasad","orcid":"https://orcid.org/0000-0001-7406-6246","observed_orcids":["https://orcid.org/0000-0001-7406-6246"]},"institutions":[{"id":"https://openalex.org/I932239252","display_name":"SASTRA University","ror":"https://ror.org/032jk8892","country_code":"IN","type":"education","lineage":["https://openalex.org/I932239252"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Bhanuvalli R. Shamprasad","raw_affiliation_strings":["Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India","institution_ids":["https://openalex.org/I932239252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103169415","display_name":"Sriram Sridharan","orcid":"https://orcid.org/0000-0002-2246-1516","observed_orcids":["https://orcid.org/0000-0002-2246-1516"]},"institutions":[{"id":"https://openalex.org/I932239252","display_name":"SASTRA University","ror":"https://ror.org/032jk8892","country_code":"IN","type":"education","lineage":["https://openalex.org/I932239252"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sriram Sridharan","raw_affiliation_strings":["Centre for Advanced Research in Indian System of Medicine, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Advanced Research in Indian System of Medicine, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India","institution_ids":["https://openalex.org/I932239252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009927722","display_name":"Ravichandran Natesan","orcid":"https://orcid.org/0000-0003-3960-7152","observed_orcids":["https://orcid.org/0000-0003-3960-7152"]},"institutions":[{"id":"https://openalex.org/I932239252","display_name":"SASTRA University","ror":"https://ror.org/032jk8892","country_code":"IN","type":"education","lineage":["https://openalex.org/I932239252"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ravichandran Natesan","raw_affiliation_strings":["Centre for Advanced Research in Indian System of Medicine, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Advanced Research in Indian System of Medicine, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India","institution_ids":["https://openalex.org/I932239252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077360149","display_name":"Saisubramanian Nagarajan","orcid":"https://orcid.org/0000-0003-1755-3763","observed_orcids":["https://orcid.org/0000-0003-1755-3763"]},"institutions":[{"id":"https://openalex.org/I932239252","display_name":"SASTRA University","ror":"https://ror.org/032jk8892","country_code":"IN","type":"education","lineage":["https://openalex.org/I932239252"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Saisubramanian Nagarajan","raw_affiliation_strings":["Centre for Research on Infectious Diseases, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India. sai@scbt.sastra.edu","Centre for Research on Infectious Diseases, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Research on Infectious Diseases, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India. sai@scbt.sastra.edu","institution_ids":["https://openalex.org/I932239252"]},{"raw_affiliation_string":"Centre for Research on Infectious Diseases, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India","institution_ids":["https://openalex.org/I932239252"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057182378","display_name":"Arvind Sivasubramanian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I932239252","display_name":"SASTRA University","ror":"https://ror.org/032jk8892","country_code":"IN","type":"education","lineage":["https://openalex.org/I932239252"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Arvind Sivasubramanian","raw_affiliation_strings":["Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India. arvi@biotech.sastra.edu","Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India. arvi@biotech.sastra.edu","institution_ids":["https://openalex.org/I932239252"]},{"raw_affiliation_string":"Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India","institution_ids":["https://openalex.org/I932239252"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5057182378","https://openalex.org/A5077360149"],"corresponding_institution_ids":["https://openalex.org/I932239252"],"apc_list":{"value":2390,"currency":"USD","value_usd":2390},"apc_paid":{"value":2390,"currency":"USD","value_usd":2390},"fwci":0.4718,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.47070358,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"13","issue":"1","first_page":"16407","last_page":"16407"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.8335000276565552,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.8335000276565552,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.10209999978542328,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.9409999847412109},{"id":"https://openalex.org/keywords/total-flavonoid-content","display_name":"total flavonoid content","score":0.7269999980926514},{"id":"https://openalex.org/keywords/total-phenolic-content","display_name":"total phenolic content","score":0.925000011920929},{"id":"https://openalex.org/keywords/copper-nanoparticles","display_name":"copper nanoparticles","score":0.8809999823570251},{"id":"https://openalex.org/keywords/nanoconjugates","display_name":"nanoconjugates","score":0.7940000295639038},{"id":"https://openalex.org/keywords/antibiofilm-activity","display_name":"antibiofilm activity","score":0.9190000295639038},{"id":"https://openalex.org/keywords/methicillin-resistant-staphylococcus-aureus","display_name":"methicillin-resistant Staphylococcus aureus","score":0.9369999766349792},{"id":"https://openalex.org/keywords/zebrafish-infection-model","display_name":"zebrafish infection model","score":0.8569999933242798},{"id":"https://openalex.org/keywords/biocompatibility","display_name":"biocompatibility","score":0.7129999995231628},{"id":"https://openalex.org/keywords/plant-derived-antimicrobials","display_name":"plant-derived antimicrobials","score":0.5320000052452087}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.8368526697158813},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.6082507371902466},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5368291735649109},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4596537947654724},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4269043207168579},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.32587534189224243},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3201230764389038},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2780410051345825},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.213576078414917},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.07782614231109619},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005419","descriptor_name":"Flavonoids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029864","descriptor_name":"Crotalaria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055624","descriptor_name":"Methicillin-Resistant Staphylococcus aureus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058726","descriptor_name":"Nanoconjugates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41598-023-43574-0","doi":"https://doi.org/10.1038/s41598-023-43574-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-023-43574-0","pdf_url":"https://www.nature.com/articles/s41598-023-43574-0.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-2884284/v1","doi":"https://doi.org/10.21203/rs.3.rs-2884284/v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.21203/rs.3.rs-2884284/v1","pdf_url":"https://www.researchsquare.com/article/rs-2884284/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10541877","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10541877","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10541877/pdf/41598_2023_Article_43574.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmid:37775527","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37775527","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:f19184da094545d29ab81e17012e2cbd","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/f19184da094545d29ab81e17012e2cbd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41598-023-43574-0","doi":"https://doi.org/10.1038/s41598-023-43574-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-023-43574-0","pdf_url":"https://www.nature.com/articles/s41598-023-43574-0.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.428600013256073,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3933997254","display_name":null,"funder_award_id":"SR/FST/CS-I/2018/62","funder_id":"https://openalex.org/F4320334771","funder_display_name":"Science and Engineering Research Board"},{"id":"https://openalex.org/G4687914250","display_name":null,"funder_award_id":"CRG/2020/001063","funder_id":"https://openalex.org/F4320334771","funder_display_name":"Science and Engineering Research Board"},{"id":"https://openalex.org/G902043827","display_name":null,"funder_award_id":"SR/ FST/CS-I/2018/62","funder_id":"https://openalex.org/F4320320719","funder_display_name":"Department of Science and Technology, Ministry of Science and Technology, India"}],"funders":[{"id":"https://openalex.org/F4320320719","display_name":"Department of Science and Technology, Ministry of Science and Technology, India","ror":"https://ror.org/0101xrq71"},{"id":"https://openalex.org/F4320320720","display_name":"Indian Council of Medical Research","ror":"https://ror.org/0492wrx28"},{"id":"https://openalex.org/F4320334771","display_name":"Science and Engineering Research Board","ror":"https://ror.org/03ffdsr55"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387166757.pdf","grobid_xml":"https://content.openalex.org/works/W4387166757.grobid-xml"},"referenced_works_count":72,"referenced_works":["https://openalex.org/W365713858","https://openalex.org/W1775749144","https://openalex.org/W1956847310","https://openalex.org/W1963700481","https://openalex.org/W1965825438","https://openalex.org/W1966478139","https://openalex.org/W1968758930","https://openalex.org/W1971048984","https://openalex.org/W1994369978","https://openalex.org/W1999621887","https://openalex.org/W2009547038","https://openalex.org/W2012772197","https://openalex.org/W2021995332","https://openalex.org/W2024450406","https://openalex.org/W2024965429","https://openalex.org/W2031596649","https://openalex.org/W2038857564","https://openalex.org/W2043533197","https://openalex.org/W2052399396","https://openalex.org/W2068712421","https://openalex.org/W2069978879","https://openalex.org/W2071990737","https://openalex.org/W2084912789","https://openalex.org/W2111732308","https://openalex.org/W2120619108","https://openalex.org/W2123033342","https://openalex.org/W2125199093","https://openalex.org/W2144093850","https://openalex.org/W2149852613","https://openalex.org/W2195969652","https://openalex.org/W2302392374","https://openalex.org/W2406546035","https://openalex.org/W2418269076","https://openalex.org/W2538201653","https://openalex.org/W2693085860","https://openalex.org/W2727706582","https://openalex.org/W2736011622","https://openalex.org/W2771151886","https://openalex.org/W2793685188","https://openalex.org/W2806314370","https://openalex.org/W2883779460","https://openalex.org/W2888120636","https://openalex.org/W2888201183","https://openalex.org/W2891597519","https://openalex.org/W2911684188","https://openalex.org/W2944317616","https://openalex.org/W2959988299","https://openalex.org/W2965604730","https://openalex.org/W2966099985","https://openalex.org/W2979586952","https://openalex.org/W2985004336","https://openalex.org/W2986044326","https://openalex.org/W3007214330","https://openalex.org/W3021374105","https://openalex.org/W3037842701","https://openalex.org/W3040174754","https://openalex.org/W3049317096","https://openalex.org/W3110883955","https://openalex.org/W3151433163","https://openalex.org/W3170111182","https://openalex.org/W3197576356","https://openalex.org/W3198669059","https://openalex.org/W3210244342","https://openalex.org/W4200558346","https://openalex.org/W4206075151","https://openalex.org/W4206130786","https://openalex.org/W4225136338","https://openalex.org/W4285262468","https://openalex.org/W4293062558","https://openalex.org/W4293315946","https://openalex.org/W4294117312","https://openalex.org/W4308181764"],"related_works":["https://openalex.org/W4417182086","https://openalex.org/W4225136338","https://openalex.org/W7214426701","https://openalex.org/W4389950403","https://openalex.org/W6911754785","https://openalex.org/W3093833430","https://openalex.org/W2887467258","https://openalex.org/W2944317616","https://openalex.org/W7219550483","https://openalex.org/W7196960328"],"abstract_inverted_index":{"Crotalaria":[0],"genus":[1],"is":[2,12],"extensively":[3],"dispersed":[4],"in":[5,241],"tropical":[6],"and":[7,10,46,67,86,90,136,142,151,163,180,190,233,254],"subtropical":[8],"provinces,":[9],"it":[11],"found":[13,76],"to":[14,92,130,154,185],"harbor":[15],"antioxidant":[16,125],"flavonoids.":[17,123],"Response":[18],"surface":[19],"methodology-based":[20],"optimization":[21],"was":[22],"carried":[23],"out":[24],"for":[25,53,231,236],"the":[26,38,94,104,118,132,156,159,169,196,208,218,250],"purpose":[27],"of":[28,55,115,120,158,195,227],"efficient":[29],"extraction":[30,54,68],"involving":[31],"a":[32,225],"suitable":[33],"solvent":[34],"which":[35,167],"can":[36],"maximize":[37],"yield":[39,105],"along":[40],"with":[41,103,207,238,246],"higher":[42],"total":[43,47],"phenolic":[44],"content":[45,49],"flavonoid":[48],"(TFC).":[50],"Optimization":[51],"conditions":[52,74],"C.candicans":[56],"flavonoids":[57,126],"(CCF)":[58],"based":[59],"on":[60,202],"variables":[61],"such":[62],"as":[63,77,96,199],"solvent,":[64],"solid-solvent":[65],"ratio":[66,83],"temperature":[69,87],"were":[70,75,127,144,183,252],"evaluated.":[71],"The":[72,124,140,193,214],"optimized":[73],"Solvent":[78],"i.e.,":[79],"Aqueous-ethanol":[80],"(53.42%),":[81],"Solid-solvent":[82],"(1:15.83":[84],"w/v)":[85],"(44.42":[88],"\u00b0C)":[89],"resulted":[91],"obtain":[93],"TFC":[95],"176.23":[97],"mg":[98,107],"QRET/g":[99],"C.":[100],"candicans":[101,110],"extract":[102],"27.42":[106],"CCF/g":[108],"(C.":[109],"dry":[111],"weight).":[112],"LC-MS":[113],"analysis":[114],"CCF,":[116],"revealed":[117],"presence":[119,157],"seven":[121],"major":[122],"further":[128],"used":[129],"functionalize":[131],"zero-valent":[133],"silver":[134],"(ZVAgF)":[135],"copper":[137],"(ZVCuF)":[138],"nanoparticles.":[139],"ZVAgF":[141],"ZVCuF":[143,232],"investigated":[145],"using":[146],"UV-Vis":[147],"spectrophotometry,":[148],"FT-IR":[149],"spectroscopy":[150],"X-ray":[152],"diffractometry":[153],"confirm":[155],"zero":[160],"valent":[161],"metals":[162],"possible":[164],"functional":[165],"groups":[166],"capped":[168],"elemental":[170],"metal.":[171],"Further":[172],"transmission":[173],"electron":[174],"microscopy,":[175],"dynamic":[176],"light":[177],"scattering":[178],"method":[179],"zeta-potential":[181],"studies":[182,210],"done":[184],"understand":[186],"their":[187],"respective":[188],"structural":[189],"morphological":[191],"properties.":[192],"efficacy":[194],"as-prepared":[197],"ZVAgF/ZVCuF":[198],"antibiofilm":[200],"agents":[201],"Methicillin-resistant":[203],"Staphylococcus":[204],"aureus":[205],"(MRSA)":[206],"mechanism":[209],"have":[211],"been":[212],"explored.":[213],"MRSA-colony":[215],"count":[216],"from":[217],"infection":[219],"zebrafish":[220],"(in":[221],"vivo)":[222],"model,":[223],"portrayed":[224],"reduction":[226],">":[228,234],"1.9":[229],"fold":[230],"twofold":[235],"ZVAgF,":[237,247],"no":[239],"alteration":[240],"liver":[242],"morphology":[243],"when":[244],"treated":[245],"implying":[248],"that":[249],"nanoparticles":[251],"safe":[253],"biocompatible.":[255]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2023-09-30T00:00:00"}
