{"id":"https://openalex.org/W4387138552","doi":"https://doi.org/10.1163/18762891-20230004","title":"Assessment of the safety of Levilactobacillus brevis CNCM I-5321, a probiotic candidate strain isolated from pulque with anti-proliferative activities","display_name":"Assessment of the safety of Levilactobacillus brevis CNCM I-5321, a probiotic candidate strain isolated from pulque with anti-proliferative activities","publication_year":2023,"publication_date":"2023-09-01","ids":{"openalex":"https://openalex.org/W4387138552","doi":"https://doi.org/10.1163/18762891-20230004","pmid":"https://pubmed.ncbi.nlm.nih.gov/38661393"},"language":"en","primary_location":{"id":"doi:10.1163/18762891-20230004","doi":"https://doi.org/10.1163/18762891-20230004","is_oa":true,"landing_page_url":"https://doi.org/10.1163/18762891-20230004","pdf_url":"https://brill.com/downloadpdf/journals/bm/aop/article-10.1163-18762891-20230004/article-10.1163-18762891-20230004.pdf","source":{"id":"https://openalex.org/S150142394","display_name":"Beneficial Microbes","issn_l":"1876-2883","issn":["1876-2883","1876-2891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Beneficial Microbes","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://brill.com/downloadpdf/journals/bm/aop/article-10.1163-18762891-20230004/article-10.1163-18762891-20230004.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023850181","display_name":"Edgar Torres-Maravilla","orcid":"https://orcid.org/0000-0002-3359-4517","observed_orcids":["https://orcid.org/0000-0002-3359-4517"]},"institutions":[{"id":"https://openalex.org/I22248866","display_name":"AgroParisTech","ror":"https://ror.org/02kbmgc12","country_code":"FR","type":"education","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I3017594750","display_name":"Microbiologie de l\u2019alimentation au service de la sant\u00e9","ror":"https://ror.org/0471cyx86","country_code":"FR","type":"facility","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"E. Torres-Maravilla","raw_affiliation_strings":["Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France"],"raw_orcid":"https://orcid.org/0000-0002-3359-4517","affiliations":[{"raw_affiliation_string":"Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France","institution_ids":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009671839","display_name":"Anne-Sophie Boucard","orcid":"https://orcid.org/0000-0002-8109-0954","observed_orcids":["https://orcid.org/0000-0002-8109-0954"]},"institutions":[{"id":"https://openalex.org/I22248866","display_name":"AgroParisTech","ror":"https://ror.org/02kbmgc12","country_code":"FR","type":"education","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I3017594750","display_name":"Microbiologie de l\u2019alimentation au service de la sant\u00e9","ror":"https://ror.org/0471cyx86","country_code":"FR","type":"facility","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A.-S. Boucard","raw_affiliation_strings":["Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France"],"raw_orcid":"https://orcid.org/0000-0002-8109-0954","affiliations":[{"raw_affiliation_string":"Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France","institution_ids":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. Al\u00a0Azzaz","orcid":"https://orcid.org/0009-0004-5637-8982","observed_orcids":["https://orcid.org/0009-0004-5637-8982"]},"institutions":[{"id":"https://openalex.org/I22248866","display_name":"AgroParisTech","ror":"https://ror.org/02kbmgc12","country_code":"FR","type":"education","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I3017594750","display_name":"Microbiologie de l\u2019alimentation au service de la sant\u00e9","ror":"https://ror.org/0471cyx86","country_code":"FR","type":"facility","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J. Al\u00a0Azzaz","raw_affiliation_strings":["SATT Paris Saclay, 86 Rue de Paris, 91400 Orsay, France","Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France"],"raw_orcid":"https://orcid.org/0009-0004-5637-8982","affiliations":[{"raw_affiliation_string":"SATT Paris Saclay, 86 Rue de Paris, 91400 Orsay, France","institution_ids":[]},{"raw_affiliation_string":"Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France","institution_ids":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088286858","display_name":"Sophie Gontier","orcid":"https://orcid.org/0000-0001-8784-203X","observed_orcids":["https://orcid.org/0000-0001-8784-203X"]},"institutions":[{"id":"https://openalex.org/I22248866","display_name":"AgroParisTech","ror":"https://ror.org/02kbmgc12","country_code":"FR","type":"education","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I3017594750","display_name":"Microbiologie de l\u2019alimentation au service de la sant\u00e9","ror":"https://ror.org/0471cyx86","country_code":"FR","type":"facility","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S. Gontier","raw_affiliation_strings":["Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France"],"raw_orcid":"https://orcid.org/0000-0001-8784-203X","affiliations":[{"raw_affiliation_string":"Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France","institution_ids":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082811089","display_name":"Saulius Kulakauskas","orcid":"https://orcid.org/0000-0002-3466-8266","observed_orcids":["https://orcid.org/0000-0002-3466-8266"]},"institutions":[{"id":"https://openalex.org/I22248866","display_name":"AgroParisTech","ror":"https://ror.org/02kbmgc12","country_code":"FR","type":"education","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I3017594750","display_name":"Microbiologie de l\u2019alimentation au service de la sant\u00e9","ror":"https://ror.org/0471cyx86","country_code":"FR","type":"facility","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S. Kulakauskas","raw_affiliation_strings":["Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France"],"raw_orcid":"https://orcid.org/0000-0002-3466-8266","affiliations":[{"raw_affiliation_string":"Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France","institution_ids":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076433007","display_name":"Philippe Langella","orcid":"https://orcid.org/0000-0001-5960-4341","observed_orcids":["https://orcid.org/0000-0001-5960-4341","https://orcid.org/0009-0002-7882-3464"]},"institutions":[{"id":"https://openalex.org/I22248866","display_name":"AgroParisTech","ror":"https://ror.org/02kbmgc12","country_code":"FR","type":"education","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I3017594750","display_name":"Microbiologie de l\u2019alimentation au service de la sant\u00e9","ror":"https://ror.org/0471cyx86","country_code":"FR","type":"facility","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"P. Langella","raw_affiliation_strings":["Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France"],"raw_orcid":"https://orcid.org/0000-0001-5960-4341","affiliations":[{"raw_affiliation_string":"Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France","institution_ids":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041676346","display_name":"Luis G. Berm\u00fadez\u2010Humar\u00e1n","orcid":"https://orcid.org/0000-0001-7525-3131","observed_orcids":["https://orcid.org/0000-0001-7525-3131"]},"institutions":[{"id":"https://openalex.org/I22248866","display_name":"AgroParisTech","ror":"https://ror.org/02kbmgc12","country_code":"FR","type":"education","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I3017594750","display_name":"Microbiologie de l\u2019alimentation au service de la sant\u00e9","ror":"https://ror.org/0471cyx86","country_code":"FR","type":"facility","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"L.G. Bermu\u0301dez-Humara\u0301n","raw_affiliation_strings":["Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France"],"raw_orcid":"https://orcid.org/0000-0001-7525-3131","affiliations":[{"raw_affiliation_string":"Universite\u0301 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Domain de Vilvert, 78350 Jouy-en-Josas, France","institution_ids":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I3017594750","https://openalex.org/I4210088668"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":{"value":2400,"currency":"EUR","value_usd":2588},"fwci":0.7968,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.66456186,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":97},"biblio":{"volume":"14","issue":"4","first_page":"335","last_page":"348"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12996","display_name":"Bacterial Cancer Therapy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/levilactobacillus-brevis","display_name":"Lactobacillus brevis","score":0.9309999942779541},{"id":"https://openalex.org/keywords/probiotic-safety","display_name":"probiotic safety","score":0.8399999737739563},{"id":"https://openalex.org/keywords/pulque","display_name":"pulque","score":0.9570000171661377},{"id":"https://openalex.org/keywords/fermented-beverages","display_name":"fermented beverages","score":0.6100000143051147},{"id":"https://openalex.org/keywords/colorectal-cancer-prevention","display_name":"colorectal cancer prevention","score":0.8270000219345093},{"id":"https://openalex.org/keywords/antiproliferative-activity","display_name":"antiproliferative activity","score":0.9269999861717224},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.8029999732971191},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8730000257492065},{"id":"https://openalex.org/keywords/caspase-8","display_name":"caspase-8","score":0.9800000190734863},{"id":"https://openalex.org/keywords/antibiotic-resistance","display_name":"antibiotic resistance","score":0.7720000147819519},{"id":"https://openalex.org/keywords/horizontal-gene-transfer","display_name":"horizontal gene transfer","score":0.8130000233650208},{"id":"https://openalex.org/keywords/chicken-embryo-chorioallantoic-membrane","display_name":"chicken embryo chorioallantoic membrane","score":0.843999981880188},{"id":"https://openalex.org/keywords/gut-dysbiosis","display_name":"gut dysbiosis","score":0.7239999771118164}],"concepts":[{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.8810973763465881},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6238028407096863},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5265942811965942},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5251319408416748},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18043458461761475},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.15829351544380188},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13257113099098206},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002642","descriptor_name":"Chick Embryo","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018938","descriptor_name":"Caco-2 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019073","descriptor_name":"HT29 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D045325","descriptor_name":"HCT116 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D052196","descriptor_name":"Levilactobacillus brevis","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1163/18762891-20230004","doi":"https://doi.org/10.1163/18762891-20230004","is_oa":true,"landing_page_url":"https://doi.org/10.1163/18762891-20230004","pdf_url":"https://brill.com/downloadpdf/journals/bm/aop/article-10.1163-18762891-20230004/article-10.1163-18762891-20230004.pdf","source":{"id":"https://openalex.org/S150142394","display_name":"Beneficial Microbes","issn_l":"1876-2883","issn":["1876-2883","1876-2891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Beneficial Microbes","raw_type":"journal-article"},{"id":"pmid:38661393","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38661393","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Beneficial microbes","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04565316v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.inrae.fr/hal-04565316","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Beneficial Microbes, 2023, 14 (4), pp. 335-348. ⟨10.1163/18762891-20230004⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1163/18762891-20230004","doi":"https://doi.org/10.1163/18762891-20230004","is_oa":true,"landing_page_url":"https://doi.org/10.1163/18762891-20230004","pdf_url":"https://brill.com/downloadpdf/journals/bm/aop/article-10.1163-18762891-20230004/article-10.1163-18762891-20230004.pdf","source":{"id":"https://openalex.org/S150142394","display_name":"Beneficial Microbes","issn_l":"1876-2883","issn":["1876-2883","1876-2891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Beneficial Microbes","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4597368071","display_name":"SATT PARIS SACLAY","funder_award_id":"ANR-10-SATT-0013","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320321694","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34"},{"id":"https://openalex.org/F4320321739","display_name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","ror":"https://ror.org/059ex5q34"},{"id":"https://openalex.org/F4320330625","display_name":"Soci\u00e9t\u00e9 d'Acc\u00e9l\u00e9ration du Transfert de Technologies","ror":"https://ror.org/04prezx56"},{"id":"https://openalex.org/F4320331560","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387138552.pdf","grobid_xml":"https://content.openalex.org/works/W4387138552.grobid-xml"},"referenced_works_count":86,"referenced_works":["https://openalex.org/W49996661","https://openalex.org/W371399941","https://openalex.org/W1578612848","https://openalex.org/W1594724344","https://openalex.org/W1828039188","https://openalex.org/W1981137192","https://openalex.org/W1989337144","https://openalex.org/W1994447535","https://openalex.org/W2035779227","https://openalex.org/W2042218857","https://openalex.org/W2050122274","https://openalex.org/W2063756105","https://openalex.org/W2066666506","https://openalex.org/W2085389569","https://openalex.org/W2096667285","https://openalex.org/W2098318339","https://openalex.org/W2101236684","https://openalex.org/W2120902911","https://openalex.org/W2128723829","https://openalex.org/W2139347878","https://openalex.org/W2149074973","https://openalex.org/W2149452073","https://openalex.org/W2149517064","https://openalex.org/W2156312412","https://openalex.org/W2160452746","https://openalex.org/W2176033230","https://openalex.org/W2263582754","https://openalex.org/W2294589178","https://openalex.org/W2295661866","https://openalex.org/W2300522958","https://openalex.org/W2316144419","https://openalex.org/W2317634656","https://openalex.org/W2330059638","https://openalex.org/W2345791363","https://openalex.org/W2399477716","https://openalex.org/W2466966942","https://openalex.org/W2468682710","https://openalex.org/W2491844534","https://openalex.org/W2503826119","https://openalex.org/W2596695108","https://openalex.org/W2612161536","https://openalex.org/W2619864675","https://openalex.org/W2739552165","https://openalex.org/W2743290846","https://openalex.org/W2772015744","https://openalex.org/W2790256881","https://openalex.org/W2792784505","https://openalex.org/W2794995361","https://openalex.org/W2806149007","https://openalex.org/W2885760831","https://openalex.org/W2889223410","https://openalex.org/W2890755442","https://openalex.org/W2897402242","https://openalex.org/W2897981765","https://openalex.org/W2898614328","https://openalex.org/W2908915197","https://openalex.org/W2911615375","https://openalex.org/W2923287877","https://openalex.org/W2942463136","https://openalex.org/W2967671566","https://openalex.org/W3010320114","https://openalex.org/W3013018486","https://openalex.org/W3083390178","https://openalex.org/W3108490499","https://openalex.org/W3158079511","https://openalex.org/W3160616607","https://openalex.org/W3163571580","https://openalex.org/W3166276657","https://openalex.org/W3217469358","https://openalex.org/W4211024392","https://openalex.org/W4211246989","https://openalex.org/W4224267469","https://openalex.org/W4230418102","https://openalex.org/W4232654765","https://openalex.org/W4233189129","https://openalex.org/W4234561867","https://openalex.org/W4236106489","https://openalex.org/W4241291456","https://openalex.org/W4244006029","https://openalex.org/W4250432095","https://openalex.org/W4252474431","https://openalex.org/W4253480695","https://openalex.org/W4255852734","https://openalex.org/W4285012310","https://openalex.org/W4298563669","https://openalex.org/W4302558937"],"related_works":["https://openalex.org/W2770426308","https://openalex.org/W7005288382","https://openalex.org/W2739739467","https://openalex.org/W4281485024","https://openalex.org/W4297200806","https://openalex.org/W2620808939","https://openalex.org/W2013009397","https://openalex.org/W4405582187","https://openalex.org/W4386792900","https://openalex.org/W2980264530"],"abstract_inverted_index":{"Gut":[0],"dysbiosis":[1],"has":[2,43],"been":[3],"strongly":[4],"correlated":[5],"with":[6],"colorectal":[7],"cancer":[8,101],"(CRC)":[9],"development":[10],"and":[11,23,28,82,94,106,136,139,165,230,241],"the":[12,34,148,175,191,196],"use":[13,234],"of":[14,36,131,144,160,177,187,199,208],"probiotics":[15],"to":[16,26,80,122,163,190,214],"modulate":[17],"this":[18,32,54,161,181],"imbalance":[19],"represents":[20],"a":[21,58,125,151],"potential":[22,233],"promising":[24],"therapy":[25],"prevent":[27,81],"treat":[29,83],"CRC.":[30],"For":[31],"reason,":[33],"identification":[35],"novel":[37],"probiotic":[38,78,182],"strains":[39],"from":[40,63],"diverse":[41],"origins":[42],"widely":[44],"increased":[45],"in":[46,98,111,174,239],"recent":[47],"years,":[48],"including":[49],"traditional":[50,66],"fermented":[51],"foods.":[52],"In":[53,116],"work":[55],"we":[56],"describe":[57],"new":[59],"strain":[60,162,227],"previously":[61],"isolated":[62],"pulque":[64],"(a":[65],"Mexican":[67],"beverage),":[68],"Levilactobacillus":[69],"brevis":[70],"CNCM":[71,90,118,178,200,225],"I-5321,":[72,179],"which":[73],"may":[74],"represent":[75],"an":[76,205,236],"interesting":[77],"candidate":[79,183,238],"cancer.":[84],"Indeed,":[85],"our":[86,221],"results":[87,222],"show":[88],"that":[89,224],"I-5321":[91,119,201,226],"displays":[92],"significant":[93],"specific":[95],"antiproliferative":[96],"capacities":[97],"human":[99,240],"intestinal":[100,192],"cell":[102],"lines":[103],"(HT-29,":[104],"HTC-116":[105],"Caco-2":[107],"cells),":[108],"but":[109],"not":[110],"normal":[112],"cells":[113],"(FH":[114],"cells).":[115],"addition,":[117],"is":[120,228],"able":[121],"induce:":[123],"(1)":[124],"pro-inflammatory":[126],"immune":[127],"response":[128],"through":[129],"stimulation":[130],"interleukin":[132],"(IL)-2,":[133],"IL-6,":[134],"IL-12":[135],"IL-17":[137],"cytokines":[138],"(2)":[140],"apoptosis":[141],"via":[142],"activation":[143],"caspase":[145],"8.":[146],"On":[147],"other":[149],"hand,":[150],"minimum":[152],"inhibitory":[153],"concentration":[154],"(MIC)":[155],"assay":[156],"revealed":[157],"phenotypic":[158],"resistance":[159],"ampicillin":[164],"chloramphenicol.":[166],"However,":[167],"no":[168,185],"known":[169],"transferable":[170],"determinants":[171],"were":[172],"found":[173],"genome":[176],"thus":[180],"presents":[184],"risk":[186],"horizontal":[188],"transfer":[189],"bacterial":[193],"population.":[194],"Finally,":[195],"safety":[197],"status":[198],"was":[202],"evaluated":[203],"using":[204],"innovative":[206],"model":[207],"chicken":[209],"embryo":[210],"chorioallantoic":[211],"membrane":[212],"(CAM)":[213],"assess":[215],"undesirable":[216],"and/or":[217],"toxic":[218],"effects.":[219],"Overall,":[220],"support":[223],"non-pathogenic":[229],"safe":[231],"for":[232],"as":[235],"anti-cancer":[237],"animal":[242],"medicine.":[243]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-09-29T00:00:00"}