{"id":"https://openalex.org/W4387136802","doi":"https://doi.org/10.1038/s41467-023-41832-3","title":"Metabolic crosstalk between skeletal muscle cells and liver through IRF4-FSTL1 in nonalcoholic steatohepatitis","display_name":"Metabolic crosstalk between skeletal muscle cells and liver through IRF4-FSTL1 in nonalcoholic steatohepatitis","publication_year":2023,"publication_date":"2023-09-28","ids":{"openalex":"https://openalex.org/W4387136802","doi":"https://doi.org/10.1038/s41467-023-41832-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/37770480","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10539336"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-023-41832-3","doi":"https://doi.org/10.1038/s41467-023-41832-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-023-41832-3","pdf_url":"https://www.nature.com/articles/s41467-023-41832-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-023-41832-3.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087346958","display_name":"Shanshan Guo","orcid":"https://orcid.org/0000-0003-0393-2914","observed_orcids":["https://orcid.org/0000-0003-0393-2914"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shanshan Guo","raw_affiliation_strings":["Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, 200040, China","Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, 200040, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575","https://openalex.org/I4391768242"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575","https://openalex.org/I4391768242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071185537","display_name":"Yonghao Feng","orcid":"https://orcid.org/0000-0002-2585-5203","observed_orcids":["https://orcid.org/0000-0002-2585-5203"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yonghao Feng","raw_affiliation_strings":["Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, 200040, China","Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-2585-5203","affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, 200040, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575","https://openalex.org/I4391768242"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575","https://openalex.org/I4391768242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065049243","display_name":"Xiaopeng Zhu","orcid":"https://orcid.org/0000-0001-8830-4954","observed_orcids":["https://orcid.org/0000-0001-8830-4954"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaopeng Zhu","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100381541","display_name":"Xinyi Zhang","orcid":"https://orcid.org/0000-0002-0581-9707","observed_orcids":["https://orcid.org/0000-0002-0581-9707"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinyi Zhang","raw_affiliation_strings":["Human Phenome Institute, Fudan University, Shanghai, 201203, China","Human Phenome Institute, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Human Phenome Institute, Fudan University, Shanghai, 201203, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Human Phenome Institute, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100608695","display_name":"Hui Wang","orcid":"https://orcid.org/0000-0001-7189-7087","observed_orcids":["https://orcid.org/0000-0001-7189-7087"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Wang","raw_affiliation_strings":["Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, 200438, China","Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, 200438, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103142746","display_name":"Ruwen Wang","orcid":"https://orcid.org/0009-0003-2689-2473","observed_orcids":["https://orcid.org/0009-0003-2689-2473"]},"institutions":[{"id":"https://openalex.org/I18925743","display_name":"Shanghai University of Sport","ror":"https://ror.org/0056pyw12","country_code":"CN","type":"education","lineage":["https://openalex.org/I18925743"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruwen Wang","raw_affiliation_strings":["School of Kinesiology, Shanghai University of Sport, Shanghai, 200438, China","School of Kinesiology, Shanghai University of Sport, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Kinesiology, Shanghai University of Sport, Shanghai, 200438, China","institution_ids":["https://openalex.org/I18925743"]},{"raw_affiliation_string":"School of Kinesiology, Shanghai University of Sport, Shanghai, China","institution_ids":["https://openalex.org/I18925743"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101904706","display_name":"Qiongyue Zhang","orcid":"https://orcid.org/0000-0001-6914-2849","observed_orcids":["https://orcid.org/0000-0001-6914-2849"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiongyue Zhang","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, 200040, China","Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, 200040, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100346329","display_name":"Yiming Li","orcid":"https://orcid.org/0000-0002-1828-8765","observed_orcids":["https://orcid.org/0000-0002-1828-8765","https://orcid.org/0009-0007-6670-7016"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiming Li","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, 200040, China","Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, 200040, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100644432","display_name":"Yan Ren","orcid":"https://orcid.org/0000-0002-4007-8625","observed_orcids":["https://orcid.org/0000-0002-4007-8625"]},"institutions":[{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Ren","raw_affiliation_strings":["Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China","Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-4007-8625","affiliations":[{"raw_affiliation_string":"Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China","institution_ids":["https://openalex.org/I4210098460"]},{"raw_affiliation_string":"Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100328698","display_name":"Xin Gao","orcid":"https://orcid.org/0000-0003-1864-7796","observed_orcids":["https://orcid.org/0000-0003-1864-7796"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Gao","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071078640","display_name":"Hua Bian","orcid":"https://orcid.org/0000-0001-8449-0665","observed_orcids":["https://orcid.org/0000-0001-8449-0665"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hua Bian","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. zhongshan_bh@126.com","Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. zhongshan_bh@126.com","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079052592","display_name":"Tiemin Liu","orcid":"https://orcid.org/0000-0003-2077-7653","observed_orcids":["https://orcid.org/0000-0003-2077-7653"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Tiemin Liu","raw_affiliation_strings":["Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, 200040, China. tiemin_liu@fudan.edu.cn","Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. tiemin_liu@fudan.edu.cn","Human Phenome Institute, Fudan University, Shanghai, 201203, China. tiemin_liu@fudan.edu.cn","Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, 200438, China. tiemin_liu@fudan.edu.cn","Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, China","Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China","Human Phenome Institute, Fudan University, Shanghai, China","Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, 200040, China. tiemin_liu@fudan.edu.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575","https://openalex.org/I4391768242"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. tiemin_liu@fudan.edu.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Human Phenome Institute, Fudan University, Shanghai, 201203, China. tiemin_liu@fudan.edu.cn","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, 200438, China. tiemin_liu@fudan.edu.cn","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575","https://openalex.org/I4391768242"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Human Phenome Institute, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087013074","display_name":"Huanqing Gao","orcid":"https://orcid.org/0000-0002-8567-3583","observed_orcids":["https://orcid.org/0000-0002-8567-3583"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Huanqing Gao","raw_affiliation_strings":["Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, 200040, China. gao_hq@fudan.edu.cn","Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, 200040, China. gao_hq@fudan.edu.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575","https://openalex.org/I4391768242"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575","https://openalex.org/I4391768242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011592007","display_name":"Xingxing Kong","orcid":"https://orcid.org/0000-0002-8395-0268","observed_orcids":["https://orcid.org/0000-0002-8395-0268"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]},{"id":"https://openalex.org/I4391768242","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768242"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xingxing Kong","raw_affiliation_strings":["Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, 200040, China. kongxingxing@fudan.edu.cn","Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, 200438, China. kongxingxing@fudan.edu.cn","Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, China","Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, China"],"raw_orcid":"https://orcid.org/0000-0002-8395-0268","affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, 200040, China. kongxingxing@fudan.edu.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575","https://openalex.org/I4391768242"]},{"raw_affiliation_string":"Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, 200438, China. kongxingxing@fudan.edu.cn","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"Department of Endocrinology and Metabolism, State Key Laboratory of Genetic Engineering, School of Life Sciences, Huashan Hospital, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575","https://openalex.org/I4391768242"]},{"raw_affiliation_string":"Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5011592007","https://openalex.org/A5071078640","https://openalex.org/A5079052592","https://openalex.org/A5087013074"],"corresponding_institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074","https://openalex.org/I4210159575","https://openalex.org/I4391768242"],"apc_list":{"value":6290,"currency":"USD","value_usd":6290},"apc_paid":{"value":6290,"currency":"USD","value_usd":6290},"fwci":10.3366,"has_fulltext":true,"cited_by_count":52,"citation_normalized_percentile":{"value":0.99064207,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"14","issue":"1","first_page":"6047","last_page":"6047"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-alcoholic-steatohepatitis","display_name":"nonalcoholic steatohepatitis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/irf4","display_name":"IRF4","score":0.8220000267028809},{"id":"https://openalex.org/keywords/fstl1","display_name":"FSTL1","score":0.9860000014305115},{"id":"https://openalex.org/keywords/follistatin-like-protein-1","display_name":"follistatin-like protein 1","score":0.8679999709129333},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.9660000205039978},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.871999979019165},{"id":"https://openalex.org/keywords/liver-inflammation","display_name":"liver inflammation","score":0.9010000228881836},{"id":"https://openalex.org/keywords/hormone-signaling","display_name":"hormone signaling","score":0.531000018119812}],"concepts":[{"id":"https://openalex.org/C3018708256","wikidata":"https://www.wikidata.org/wiki/Q1546498","display_name":"Nonalcoholic steatohepatitis","level":5,"score":0.9064278602600098},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.6636906862258911},{"id":"https://openalex.org/C169822122","wikidata":"https://www.wikidata.org/wiki/Q230187","display_name":"Crosstalk","level":2,"score":0.6600125432014465},{"id":"https://openalex.org/C2779478299","wikidata":"https://www.wikidata.org/wiki/Q2335423","display_name":"Steatohepatitis","level":4,"score":0.6523480415344238},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43128499388694763},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3743874430656433},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32511135935783386},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.23541811108589172},{"id":"https://openalex.org/C2776954865","wikidata":"https://www.wikidata.org/wiki/Q1546498","display_name":"Nonalcoholic fatty liver disease","level":4,"score":0.23471570014953613},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09900718927383423},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D038702","descriptor_name":"Follistatin-Related Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D038702","descriptor_name":"Follistatin-Related Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1038/s41467-023-41832-3","doi":"https://doi.org/10.1038/s41467-023-41832-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-023-41832-3","pdf_url":"https://www.nature.com/articles/s41467-023-41832-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-2271369/v1","doi":"https://doi.org/10.21203/rs.3.rs-2271369/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-2271369/v1","pdf_url":"https://www.researchsquare.com/article/rs-2271369/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10539336","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10539336","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10539336/pdf/41467_2023_Article_41832.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"pmid:37770480","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37770480","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:oai:RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-41832-3","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/s41467-023-41832-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:4ed8309e8a5544718f1a0057eb98cd3f","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/4ed8309e8a5544718f1a0057eb98cd3f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41467-023-41832-3","doi":"https://doi.org/10.1038/s41467-023-41832-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-023-41832-3","pdf_url":"https://www.nature.com/articles/s41467-023-41832-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1450670842","display_name":null,"funder_award_id":"82100849","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1654227326","display_name":null,"funder_award_id":"82200952","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2735181373","display_name":null,"funder_award_id":"82300978","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G325556353","display_name":null,"funder_award_id":"2019YFA0801900","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3504115553","display_name":null,"funder_award_id":"32371194","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4827640107","display_name":null,"funder_award_id":"32150610475","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7481492858","display_name":null,"funder_award_id":"92157203","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G758902722","display_name":"5-\u7f9f\u8272\u80fa2C\u53d7\u4f53\u5728\u8111\u5e72\u5b64\u675f\u6838/\u8ff7\u8d70\u80cc\u6838\u7ef4\u6301\u80fd\u91cf\u5e73\u8861\u548c\u8461\u8404\u7cd6\u7a33\u6001\u4f5c\u7528\u673a\u5236\u7814\u7a76","funder_award_id":"31971074","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G940187227","display_name":null,"funder_award_id":"20ZR1410200","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321851","display_name":"Fudan University","ror":"https://ror.org/013q1eq08"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"},{"id":"https://openalex.org/F4320326704","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27"},{"id":"https://openalex.org/F4320326863","display_name":"State Key Laboratory of Genetic Engineering","ror":"https://ror.org/01n3rg866"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387136802.pdf","grobid_xml":"https://content.openalex.org/works/W4387136802.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W1964873147","https://openalex.org/W2002771508","https://openalex.org/W2008359713","https://openalex.org/W2012460974","https://openalex.org/W2013579877","https://openalex.org/W2035938902","https://openalex.org/W2067740038","https://openalex.org/W2077291760","https://openalex.org/W2079614660","https://openalex.org/W2092172804","https://openalex.org/W2099787589","https://openalex.org/W2117457995","https://openalex.org/W2120569915","https://openalex.org/W2128788344","https://openalex.org/W2132067866","https://openalex.org/W2139654088","https://openalex.org/W2140899843","https://openalex.org/W2268067733","https://openalex.org/W2272188229","https://openalex.org/W2283843704","https://openalex.org/W2404306813","https://openalex.org/W2415876542","https://openalex.org/W2473248170","https://openalex.org/W2532034373","https://openalex.org/W2548399475","https://openalex.org/W2554433662","https://openalex.org/W2576488295","https://openalex.org/W2607011262","https://openalex.org/W2627050072","https://openalex.org/W2742613651","https://openalex.org/W2754145804","https://openalex.org/W2777389776","https://openalex.org/W2795549750","https://openalex.org/W2804042740","https://openalex.org/W2883203008","https://openalex.org/W2885053098","https://openalex.org/W2904043661","https://openalex.org/W2911080438","https://openalex.org/W2924084550","https://openalex.org/W2959518441","https://openalex.org/W2959566316","https://openalex.org/W2968872536","https://openalex.org/W3002055665","https://openalex.org/W3035103197","https://openalex.org/W3041782072","https://openalex.org/W3046326265","https://openalex.org/W3095186004","https://openalex.org/W3098031338","https://openalex.org/W3107038321","https://openalex.org/W3143409077","https://openalex.org/W3162364106","https://openalex.org/W3177283014","https://openalex.org/W3200425833","https://openalex.org/W4206648120","https://openalex.org/W4210895382","https://openalex.org/W4221105933","https://openalex.org/W4225413323","https://openalex.org/W4280503962","https://openalex.org/W4283012041","https://openalex.org/W4313237264","https://openalex.org/W4321436187"],"related_works":["https://openalex.org/W4408760258","https://openalex.org/W4213092543","https://openalex.org/W2150077091","https://openalex.org/W7052041163","https://openalex.org/W3044298824","https://openalex.org/W3085001696","https://openalex.org/W3206961863","https://openalex.org/W3116305102","https://openalex.org/W4298145605","https://openalex.org/W2783662278"],"abstract_inverted_index":{"Inter-organ":[0],"crosstalk":[1],"has":[2],"gained":[3],"increasing":[4],"attention":[5],"in":[6,54,97,120,142,160],"recent":[7],"times;":[8],"however,":[9],"the":[10,81,98,132,158,161],"underlying":[11],"mechanisms":[12],"remain":[13],"unclear.":[14],"In":[15,109],"this":[16],"study,":[17],"we":[18,129],"elucidate":[19],"an":[20],"endocrine":[21],"pathway":[22,149],"that":[23,69,87,114,131,152],"is":[24,103,136],"regulated":[25],"by":[26],"skeletal":[27,154],"muscle":[28,39,155],"interferon":[29],"regulatory":[30],"factor":[31],"(IRF)":[32],"4,":[33],"which":[34],"manipulates":[35],"liver":[36,107,122,159],"pathology.":[37,108],"Skeletal":[38],"specific":[40],"IRF4":[41,88],"knockout":[42],"(F4MKO)":[43],"mice":[44,102],"exhibited":[45],"ameliorated":[46],"hepatic":[47],"steatosis,":[48],"inflammation,":[49],"and":[50,80],"fibrosis,":[51],"without":[52],"changes":[53],"body":[55],"weight,":[56],"when":[57],"put":[58],"on":[59],"a":[60,76,117,147],"nonalcoholic":[61],"steatohepatitis":[62],"(NASH)":[63],"diet.":[64],"Proteomics":[65],"analysis":[66],"results":[67],"suggested":[68],"follistatin-like":[70],"protein":[71],"1":[72],"(FSTL1)":[73],"may":[74],"constitute":[75],"link":[77],"between":[78],"muscles":[79,99],"liver.":[82],"Dual":[83],"luciferase":[84],"assays":[85],"showed":[86],"can":[89],"transcriptionally":[90],"regulate":[91],"FSTL1.":[92],"Further,":[93],"inducing":[94],"FSTL1":[95,115,134],"expression":[96],"of":[100,163],"F4MKO":[101],"sufficient":[104],"to":[105,157],"restore":[106],"addition,":[110],"co-culture":[111],"experiments":[112],"confirmed":[113],"plays":[116],"distinct":[118],"role":[119],"various":[121],"cell":[123],"types":[124],"via":[125],"different":[126],"receptors.":[127],"Finally,":[128],"observed":[130],"serum":[133],"level":[135],"positively":[137],"correlated":[138],"with":[139],"NASH":[140],"progression":[141],"humans.":[143],"These":[144],"data":[145],"indicate":[146],"signaling":[148],"involving":[150],"IRF4-FSTL1-DIP2A/CD14,":[151],"links":[153],"cells":[156],"pathogenesis":[162],"NASH.":[164]},"counts_by_year":[{"year":2026,"cited_by_count":24},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":12}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-09-29T00:00:00"}