{"id":"https://openalex.org/W4387042276","doi":"https://doi.org/10.21203/rs.3.rs-3369346/v1","title":"A Lifestyle Modification Program for Secondary Prevention of Atrial Fibrillation: A Pilot Study","display_name":"A Lifestyle Modification Program for Secondary Prevention of Atrial Fibrillation: A Pilot Study","publication_year":2023,"publication_date":"2023-09-26","ids":{"openalex":"https://openalex.org/W4387042276","doi":"https://doi.org/10.21203/rs.3.rs-3369346/v1","pmid":"https://pubmed.ncbi.nlm.nih.gov/37841859","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10571629"},"language":"en","primary_location":{"id":"doi:10.21203/rs.3.rs-3369346/v1","doi":"https://doi.org/10.21203/rs.3.rs-3369346/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-3369346/v1","pdf_url":"https://www.researchsquare.com/article/rs-3369346/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.researchsquare.com/article/rs-3369346/latest.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042245461","display_name":"Jeffrey M. Ashburner","orcid":"https://orcid.org/0000-0002-5600-3492","observed_orcids":["https://orcid.org/0000-0002-5600-3492"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeffrey M. Ashburner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014773700","display_name":"Taylor D. Carmichael","orcid":"https://orcid.org/0009-0001-4276-0724","observed_orcids":["https://orcid.org/0009-0001-4276-0724"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Taylor D. Carmichael","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065207092","display_name":"Romit Bhattacharya","orcid":"https://orcid.org/0000-0002-0782-4753","observed_orcids":["https://orcid.org/0000-0002-0782-4753"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Romit Bhattacharya","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059527156","display_name":"Aneesh C. Bapat","orcid":"https://orcid.org/0000-0002-1996-522X","observed_orcids":["https://orcid.org/0000-0002-1996-522X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aneesh C. Bapat","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047884631","display_name":"Pradeep Natarajan","orcid":"https://orcid.org/0000-0001-8402-7435","observed_orcids":["https://orcid.org/0000-0001-8402-7435"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pradeep Natarajan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061398003","display_name":"Steven J. Atlas","orcid":"https://orcid.org/0000-0002-2297-9614","observed_orcids":["https://orcid.org/0000-0002-2297-9614"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven J. Atlas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020290782","display_name":"Daniel E. Singer","orcid":"https://orcid.org/0000-0001-6145-4848","observed_orcids":["https://orcid.org/0000-0001-6145-4848"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel E. Singer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5069775268","display_name":"Anne N. Thorndike","orcid":"https://orcid.org/0000-0003-1096-9221","observed_orcids":["https://orcid.org/0000-0003-1096-9221"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anne N. Thorndike","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11083","display_name":"Cardiac Health and Mental Health","score":0.6884999871253967,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11083","display_name":"Cardiac Health and Mental Health","score":0.6884999871253967,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.30880001187324524,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/secondary-prevention","display_name":"secondary prevention","score":0.7590000033378601},{"id":"https://openalex.org/keywords/lifestyle-modification","display_name":"lifestyle modification","score":0.8899999856948853},{"id":"https://openalex.org/keywords/cardiac-rehabilitation","display_name":"cardiac rehabilitation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/exercise-training","display_name":"exercise training","score":0.6589999794960022},{"id":"https://openalex.org/keywords/nutrition-education","display_name":"nutrition education","score":0.8069999814033508},{"id":"https://openalex.org/keywords/overweight-adults","display_name":"overweight adults","score":0.5600000023841858},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.8370000123977661},{"id":"https://openalex.org/keywords/atrial-fibrillation-burden","display_name":"atrial fibrillation burden","score":0.8740000128746033},{"id":"https://openalex.org/keywords/resistance-training","display_name":"resistance training","score":0.9649999737739563},{"id":"https://openalex.org/keywords/feasibility-and-acceptability","display_name":"feasibility and acceptability","score":0.7369999885559082}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9078553318977356},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.7040907740592957},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.6828885078430176},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.6820802688598633},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.6081118583679199},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.5392239689826965},{"id":"https://openalex.org/C103038586","wikidata":"https://www.wikidata.org/wiki/Q1152037","display_name":"Aerobic exercise","level":2,"score":0.4503100514411926},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.41383060812950134},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3424137234687805},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.2604895830154419},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.21203/rs.3.rs-3369346/v1","doi":"https://doi.org/10.21203/rs.3.rs-3369346/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-3369346/v1","pdf_url":"https://www.researchsquare.com/article/rs-3369346/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmid:37841859","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37841859","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research square","raw_type":"Preprint"},{"id":"pmh:oai:pubmedcentral.nih.gov:10571629","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10571629","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10571629/pdf/nihpp-rs3369346v1.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Res Sq","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.21203/rs.3.rs-3369346/v1","doi":"https://doi.org/10.21203/rs.3.rs-3369346/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-3369346/v1","pdf_url":"https://www.researchsquare.com/article/rs-3369346/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G4826437466","display_name":"Identifying primary care patients at increased risk of atrial fibrillation for screening interventions","funder_award_id":"K01HL148506","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000878224","display_name":"Mentorship in patient-oriented research on behavioral and social determinants of cardiometabolic health","funder_award_id":"K24HL163073","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387042276.pdf","grobid_xml":"https://content.openalex.org/works/W4387042276.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W2102904190","https://openalex.org/W2111786081","https://openalex.org/W2114775432","https://openalex.org/W2120192465","https://openalex.org/W2132505348","https://openalex.org/W2290411171","https://openalex.org/W2809217674","https://openalex.org/W2984917962","https://openalex.org/W3011855095","https://openalex.org/W3097924861","https://openalex.org/W4233664165"],"related_works":["https://openalex.org/W4396953478","https://openalex.org/W4389979252","https://openalex.org/W4224948009","https://openalex.org/W3155754052","https://openalex.org/W4251409834","https://openalex.org/W7212067491","https://openalex.org/W4206621073","https://openalex.org/W2651125527","https://openalex.org/W2810683998","https://openalex.org/W2012210640"],"abstract_inverted_index":{"Background:":[0],"Lifestyle":[1],"modification":[2],"programs,":[3],"such":[4],"as":[5],"cardiac":[6,42,63,184],"rehabilitation,":[7],"may":[8],"reduce":[9],"atrial":[10],"fibrillation":[11],"(AF)":[12],"burden":[13,146,207],"and":[14,34,40,70,78,83,92,98,109,111,118,133,153,189,208,210],"improve":[15],"quality":[16],"of":[17,25,37,103,165,201],"life":[18],"(QOL),":[19],"but":[20],"remain":[21],"unproven.":[22],"The":[23],"objective":[24],"this":[26],"pilot":[27],"study":[28],"was":[29,187],"to":[30,140],"assess":[31],"feasibility,":[32],"acceptability,":[33,105],"preliminary":[35,199],"effectiveness":[36,200],"an":[38],"exercise":[39,91,134],"nutrition-based":[41],"rehabilitation-like":[43],"program":[44,126,186,203],"for":[45,191,204],"AF":[46,59,115,145,206],"patients.":[47],"Methods:":[48],"We":[49],"enrolled":[50],"overweight":[51,192],"adults":[52],"aged":[53],"\u2265":[54],"30":[55],"years":[56],"with":[57,194],"symptomatic":[58,195],"in":[60,107,113,182],"a":[61,183],"12-week":[62],"lifestyle":[64],"group":[65],"program,":[66],"including":[67],"6":[68,71],"virtual":[69],"in-person":[72],"visits.":[73],"All":[74],"visits":[75,87],"included":[76,88,101],"discussion":[77],"education":[79],"about":[80],"nutrition,":[81],"exercise,":[82],"behavior":[84],"modification.":[85],"In-person":[86],"supervised":[89],"aerobic":[90],"strength":[93],"training.":[94],"Outcomes":[95],"at":[96,162],"baseline":[97],"12":[99],"weeks":[100],"feasibility":[102],"participation,":[104],"change":[106],"weight":[108],"BMI,":[110],"changes":[112,135],"survey-based":[114],"burden,":[116],"symptoms,":[117],"QOL.":[119,212],"Results:":[120],"(Range:":[121],"0-2.6).":[122],"Patients":[123,168],"found":[124],"the":[125,137,163,166,202],"helpful":[127],"overall:":[128],"all":[129],"reported":[130,143,170],"making":[131],"diet":[132],"during":[136],"program.":[138,167],"Compared":[139],"baseline,":[141],"patients":[142,193],"decreased":[144],"(12.9":[147],"vs.":[148,156,175],"11.7,":[149],"p":[150,158,177],"=":[151,159,178],"0.03)":[152],"symptom":[154],"(10.1":[155],"5.6,":[157],"0.003)":[160],"scores":[161],"conclusion":[164],"also":[169],"increased":[171],"QOL":[172],"overall":[173],"(68.9":[174],"86.4,":[176],"0.001).":[179],"Conclusions:":[180],"Participation":[181],"rehab-like":[185],"feasible":[188],"acceptable":[190],"AF.":[196],"Results":[197],"suggest":[198],"reducing":[205],"symptoms":[209],"increasing":[211]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-09-27T00:00:00"}