{"id":"https://openalex.org/W4387035682","doi":"https://doi.org/10.25163/angiotherapy.717344","title":"Moringa oleifera's Effect on Colorectal Cancer","display_name":"Moringa oleifera's Effect on Colorectal Cancer","publication_year":2023,"publication_date":"2023-08-12","ids":{"openalex":"https://openalex.org/W4387035682","doi":"https://doi.org/10.25163/angiotherapy.717344"},"language":"en","primary_location":{"id":"doi:10.25163/angiotherapy.717344","doi":"https://doi.org/10.25163/angiotherapy.717344","is_oa":true,"landing_page_url":"http://dx.doi.org/10.25163/angiotherapy.717344","pdf_url":"https://publishing.emanresearch.org/CurrentIssuePDF/EmanPublisher_1_5171angiotherapy-717344.pdf","source":{"id":"https://openalex.org/S4210188458","display_name":"Journal of Angiotherapy","issn_l":"2207-872X","issn":["2207-872X","2207-8843"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Angiotherapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://publishing.emanresearch.org/CurrentIssuePDF/EmanPublisher_1_5171angiotherapy-717344.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Rolla AlShalabi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I104941359","display_name":"Al-Ahliyya Amman University","ror":"https://ror.org/00xddhq60","country_code":"JO","type":"education","lineage":["https://openalex.org/I104941359"]},{"id":"https://openalex.org/I139322472","display_name":"Universiti Sains Malaysia","ror":"https://ror.org/02rgb2k63","country_code":"MY","type":"education","lineage":["https://openalex.org/I139322472"]}],"countries":["JO","MY"],"is_corresponding":false,"raw_author_name":"Rolla AlShalabi","raw_affiliation_strings":["Department of Toxicology , Sains@BERTAM , Advanced Medical and Dental Institute , Universiti Sains Malaysia , 13200 Kepala Batas , Penang , Malaysia","Pharmacological and Diagnostic Research Center , Faculty of Pharmacy , Al-Ahliyya Amman University , Al-Salt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology , Sains@BERTAM , Advanced Medical and Dental Institute , Universiti Sains Malaysia , 13200 Kepala Batas , Penang , Malaysia","institution_ids":["https://openalex.org/I139322472"]},{"raw_affiliation_string":"Pharmacological and Diagnostic Research Center , Faculty of Pharmacy , Al-Ahliyya Amman University , Al-Salt","institution_ids":["https://openalex.org/I104941359"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nozlena abdul samad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139322472","display_name":"Universiti Sains Malaysia","ror":"https://ror.org/02rgb2k63","country_code":"MY","type":"education","lineage":["https://openalex.org/I139322472"]}],"countries":["MY"],"is_corresponding":true,"raw_author_name":"Nozlena abdul samad","raw_affiliation_strings":["Department of Toxicology , Sains@BERTAM , Advanced Medical and Dental Institute , Universiti Sains Malaysia , 13200 Kepala Batas , Penang , Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology , Sains@BERTAM , Advanced Medical and Dental Institute , Universiti Sains Malaysia , 13200 Kepala Batas , Penang , Malaysia","institution_ids":["https://openalex.org/I139322472"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lim Vuanghao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139322472","display_name":"Universiti Sains Malaysia","ror":"https://ror.org/02rgb2k63","country_code":"MY","type":"education","lineage":["https://openalex.org/I139322472"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Lim Vuanghao","raw_affiliation_strings":["Department of Toxicology , Sains@BERTAM , Advanced Medical and Dental Institute , Universiti Sains Malaysia , 13200 Kepala Batas , Penang , Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology , Sains@BERTAM , Advanced Medical and Dental Institute , Universiti Sains Malaysia , 13200 Kepala Batas , Penang , Malaysia","institution_ids":["https://openalex.org/I139322472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019649931","display_name":"Ibrahim Al\u2010Deeb","orcid":"https://orcid.org/0000-0002-7387-0598","observed_orcids":["https://orcid.org/0000-0002-7387-0598"]},"institutions":[{"id":"https://openalex.org/I104941359","display_name":"Al-Ahliyya Amman University","ror":"https://ror.org/00xddhq60","country_code":"JO","type":"education","lineage":["https://openalex.org/I104941359"]}],"countries":["JO"],"is_corresponding":false,"raw_author_name":"Ibrahim Al Deeb","raw_affiliation_strings":["Pharmacological and Diagnostic Research Center , Faculty of Pharmacy , Al-Ahliyya Amman University , Al-Salt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacological and Diagnostic Research Center , Faculty of Pharmacy , Al-Ahliyya Amman University , Al-Salt","institution_ids":["https://openalex.org/I104941359"]}]},{"author_position":"last","author":{"id":null,"display_name":"Julia Joseph","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139322472","display_name":"Universiti Sains Malaysia","ror":"https://ror.org/02rgb2k63","country_code":"MY","type":"education","lineage":["https://openalex.org/I139322472"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Julia Joseph","raw_affiliation_strings":["Department of Toxicology , Sains@BERTAM , Advanced Medical and Dental Institute , Universiti Sains Malaysia , 13200 Kepala Batas , Penang , Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Toxicology , Sains@BERTAM , Advanced Medical and Dental Institute , Universiti Sains Malaysia , 13200 Kepala Batas , Penang , Malaysia","institution_ids":["https://openalex.org/I139322472"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I139322472"],"apc_list":null,"apc_paid":null,"fwci":0.5539,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.59922716,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"7","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12721","display_name":"Moringa oleifera research and applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12721","display_name":"Moringa oleifera research and applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13792","display_name":"Morinda citrifolia extract uses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/moringa-oleifera","display_name":"Moringa oleifera","score":1.0},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.9229999780654907},{"id":"https://openalex.org/keywords/phytochemicals","display_name":"phytochemicals","score":0.9810000061988831},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.8220000267028809},{"id":"https://openalex.org/keywords/phenolic-acids","display_name":"phenolic acids","score":0.9779999852180481},{"id":"https://openalex.org/keywords/glucosinolates","display_name":"glucosinolates","score":0.7929999828338623},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.7609999775886536},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.9340000152587891},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.6100000143051147},{"id":"https://openalex.org/keywords/cell-cycle-regulation","display_name":"cell cycle regulation","score":0.7279999852180481},{"id":"https://openalex.org/keywords/angiogenesis-inhibition","display_name":"angiogenesis inhibition","score":0.777999997138977},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9520000219345093},{"id":"https://openalex.org/keywords/cancer-cell-lines","display_name":"cancer cell lines","score":0.6320000290870667},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.703000009059906},{"id":"https://openalex.org/keywords/plant-extracts","display_name":"plant extracts","score":0.7149999737739563}],"concepts":[{"id":"https://openalex.org/C2776836740","wikidata":"https://www.wikidata.org/wiki/Q310468","display_name":"Moringa","level":2,"score":0.8066916465759277},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.7528773546218872},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.581254780292511},{"id":"https://openalex.org/C2778362808","wikidata":"https://www.wikidata.org/wiki/Q375837","display_name":"Gallic acid","level":3,"score":0.526285707950592},{"id":"https://openalex.org/C2777810353","wikidata":"https://www.wikidata.org/wiki/Q393336","display_name":"Kaempferol","level":4,"score":0.5009639263153076},{"id":"https://openalex.org/C2781263971","wikidata":"https://www.wikidata.org/wiki/Q409478","display_name":"Quercetin","level":3,"score":0.4795472323894501},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.44164785742759705},{"id":"https://openalex.org/C2775963812","wikidata":"https://www.wikidata.org/wiki/Q407857","display_name":"Rutin","level":3,"score":0.43091148138046265},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4201093018054962},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.33846375346183777},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3031045198440552},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2150489091873169},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08028173446655273}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.25163/angiotherapy.717344","doi":"https://doi.org/10.25163/angiotherapy.717344","is_oa":true,"landing_page_url":"http://dx.doi.org/10.25163/angiotherapy.717344","pdf_url":"https://publishing.emanresearch.org/CurrentIssuePDF/EmanPublisher_1_5171angiotherapy-717344.pdf","source":{"id":"https://openalex.org/S4210188458","display_name":"Journal of Angiotherapy","issn_l":"2207-872X","issn":["2207-872X","2207-8843"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Angiotherapy","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.25163/angiotherapy.717344","doi":"https://doi.org/10.25163/angiotherapy.717344","is_oa":true,"landing_page_url":"http://dx.doi.org/10.25163/angiotherapy.717344","pdf_url":"https://publishing.emanresearch.org/CurrentIssuePDF/EmanPublisher_1_5171angiotherapy-717344.pdf","source":{"id":"https://openalex.org/S4210188458","display_name":"Journal of Angiotherapy","issn_l":"2207-872X","issn":["2207-872X","2207-8843"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Angiotherapy","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387035682.pdf","grobid_xml":"https://content.openalex.org/works/W4387035682.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1127309197","https://openalex.org/W7098855163","https://openalex.org/W4402876765","https://openalex.org/W4224070220","https://openalex.org/W3109187613","https://openalex.org/W4400459934","https://openalex.org/W4401090326","https://openalex.org/W4415923524","https://openalex.org/W7171492248","https://openalex.org/W4205774950"],"abstract_inverted_index":{"Background:":[0],"Moringa":[1,90,179,203,237,254,283],"oleifera,":[2],"which":[3,22,87],"is":[4,23,290],"a":[5,24,49,114],"rich":[6],"plant":[7],"with":[8,73],"diverse":[9,198],"active":[10,118],"components,":[11],"shows":[12],"promising":[13,162],"potential":[14,59,299],"in":[15,54,61,106,255,284,300],"cancer":[16,21,107,128,194,246,301],"research,":[17],"especially":[18,211],"concerning":[19],"colorectal":[20,63,94,101,127,167,193,245,286],"major":[25],"global":[26],"cause":[27],"of":[28,52,153,164,177,202,233,236,253,282,297],"mortality.":[29],"Its":[30],"phytochemicals,":[31,210],"such":[32,181,214],"as":[33,85,113,182,205,215],"flavonoids,":[34],"phenolic":[35],"acids,":[36],"alkaloids,":[37],"and":[38,44,108,123,134,149,161,186,224],"glucosinolates,":[39],"contribute":[40],"to":[41,146,156,292],"its":[42,58,130,209,298],"antioxidant":[43,212],"anti-inflammatory":[45],"properties,":[46],"making":[47],"it":[48],"compelling":[50],"subject":[51],"investigation":[53],"various":[55,192,244],"fields,":[56],"including":[57,129],"role":[60],"combating":[62],"cancer.":[64,95,168,287],"Methods:":[65],"This":[66,81,227],"narrative":[67],"review":[68,228,272],"was":[69,82,139],"conducted":[70],"by":[71],"starting":[72],"determining":[74],"the":[75,151,154,158,178,231,251,267,271,278],"targeted":[76],"topics":[77],"for":[78],"our":[79],"research.":[80],"then":[83],"used":[84,98],"keywords":[86,97],"focused":[88],"on":[89,93,191,208,243],"oleifera's":[91],"effect":[92],"The":[96,200],"were:":[99],"cancer,":[100,102],"angiogenesis,":[103,109],"natural":[104],"products":[105],"MO":[110,112,117,120,124,165],"plant,":[111,116,180],"medicinal":[115],"component,":[119],"therapeutic":[121],"potential,":[122],"effectiveness":[125,163],"against":[126,166],"leaves,":[131,184],"seeds,":[132,183,241],"fruit,":[133],"root.":[135],"After":[136],"that":[137,172],"data":[138],"collected":[140],"from":[141,174],"more":[142],"than":[143],"99":[144],"articles":[145],"identify,":[147],"summarize,":[148],"reflect":[150],"target":[152],"research":[155,289],"approve":[157],"multiple":[159],"unique":[160],"Results:":[169],"Research":[170],"indicates":[171],"extracts":[173],"different":[175,234],"parts":[176,235],"fruits,":[185,240],"roots,":[187],"exhibit":[188],"anticancer":[189,206],"effects":[190,252],"cell":[195,247,257,268],"lines":[196],"through":[197],"mechanisms.":[199],"ability":[201],"oleifera":[204,238],"relies":[207],"phenols":[213],"gallic":[216],"acid,":[217,219],"chlorogenic":[218],"rutin,":[220],"apigenin,":[221],"astragalin,":[222],"quercetin,":[223],"kaempferol.":[225],"Conclusion:":[226],"thoroughly":[229],"explores":[230],"impact":[232],"(leaves,":[239],"roots)":[242],"lines.":[248],"It":[249],"confirms":[250],"regulating":[256],"proliferation,":[258],"inducing":[259],"apoptosis,":[260],"generating":[261],"reactive":[262],"oxygen":[263],"species,":[264],"and/or":[265],"modulating":[266],"cycle.":[269],"However,":[270],"has":[273],"not":[274],"yet":[275],"definitively":[276],"confirmed":[277],"specific":[279],"anti-angiogenesis":[280],"mechanism":[281],"combatting":[285],"Further":[288],"required":[291],"fully":[293],"elucidate":[294],"this":[295],"aspect":[296],"treatment.":[302]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-09-27T00:00:00"}