{"id":"https://openalex.org/W4386979671","doi":"https://doi.org/10.1080/14786419.2023.2260068","title":"UHPLC-MS characterisation of principal triterpene glycosides and biological activities of different solvent extracts of Allochrusa gypsophiloides (Caryophyllaceae)","display_name":"UHPLC-MS characterisation of principal triterpene glycosides and biological activities of different solvent extracts of Allochrusa gypsophiloides (Caryophyllaceae)","publication_year":2023,"publication_date":"2023-09-23","ids":{"openalex":"https://openalex.org/W4386979671","doi":"https://doi.org/10.1080/14786419.2023.2260068","pmid":"https://pubmed.ncbi.nlm.nih.gov/37740590"},"language":"en","primary_location":{"id":"doi:10.1080/14786419.2023.2260068","doi":"https://doi.org/10.1080/14786419.2023.2260068","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14786419.2023.2260068","pdf_url":null,"source":{"id":"https://openalex.org/S205999849","display_name":"Natural Product Research","issn_l":"1478-6419","issn":["1478-6419","1478-6427"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural Product Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068867257","display_name":"Rano Z. Mamadalieva","orcid":"https://orcid.org/0000-0002-7490-5908","observed_orcids":["https://orcid.org/0000-0002-7490-5908"]},"institutions":[{"id":"https://openalex.org/I4210124473","display_name":"Kokand State Pedagogical Institute named after Mukimi","ror":"https://ror.org/0362r6n51","country_code":"UZ","type":"education","lineage":["https://openalex.org/I4210124473"]}],"countries":["UZ"],"is_corresponding":true,"raw_author_name":"Rano Mamadalieva","raw_affiliation_strings":["Kokand State Pedagogical Institute, Kokand, Uzbekistan"],"raw_orcid":"https://orcid.org/0000-0002-7490-5908","affiliations":[{"raw_affiliation_string":"Kokand State Pedagogical Institute, Kokand, Uzbekistan","institution_ids":["https://openalex.org/I4210124473"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092926650","display_name":"Vahobjon Umarovich Xo\u2018jayev","orcid":"https://orcid.org/0009-0001-9922-3989","observed_orcids":["https://orcid.org/0009-0001-9922-3989"]},"institutions":[{"id":"https://openalex.org/I4210124473","display_name":"Kokand State Pedagogical Institute named after Mukimi","ror":"https://ror.org/0362r6n51","country_code":"UZ","type":"education","lineage":["https://openalex.org/I4210124473"]}],"countries":["UZ"],"is_corresponding":false,"raw_author_name":"Vaxobjon Xujayev","raw_affiliation_strings":["Kokand State Pedagogical Institute, Kokand, Uzbekistan"],"raw_orcid":"https://orcid.org/0009-0001-9922-3989","affiliations":[{"raw_affiliation_string":"Kokand State Pedagogical Institute, Kokand, Uzbekistan","institution_ids":["https://openalex.org/I4210124473"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069549911","display_name":"Farukh S. Sharopov","orcid":"https://orcid.org/0000-0003-0378-8887","observed_orcids":["https://orcid.org/0000-0003-0378-8887"]},"institutions":[{"id":"https://openalex.org/I200705115","display_name":"Academy of Sciences of the Republic of Tajikistan","ror":"https://ror.org/040em2e23","country_code":"TJ","type":"education","lineage":["https://openalex.org/I200705115"]}],"countries":["TJ"],"is_corresponding":false,"raw_author_name":"Farukh S. Sharopov","raw_affiliation_strings":["Research Institution \u201cChinese-Tajik Innovation Center for Natural Products,\u201d National Academy of Sciences of Tajikistan, Dushanbe, Tajikistan"],"raw_orcid":"https://orcid.org/0000-0003-0378-8887","affiliations":[{"raw_affiliation_string":"Research Institution \u201cChinese-Tajik Innovation Center for Natural Products,\u201d National Academy of Sciences of Tajikistan, Dushanbe, Tajikistan","institution_ids":["https://openalex.org/I200705115"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034011528","display_name":"Micha\u00ebl Wink","orcid":"https://orcid.org/0000-0002-7875-4510","observed_orcids":["https://orcid.org/0000-0002-7875-4510"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael Wink","raw_affiliation_strings":["Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany"],"raw_orcid":"https://orcid.org/0000-0002-7875-4510","affiliations":[{"raw_affiliation_string":"Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5068867257"],"corresponding_institution_ids":["https://openalex.org/I4210124473"],"apc_list":null,"apc_paid":null,"fwci":0.4865,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.45544293,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"38","issue":"21","first_page":"3818","last_page":"3822"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.9609000086784363,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.9609000086784363,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12215","display_name":"Phytochemical Studies and Bioactivities","score":0.03830000013113022,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/triterpenoid-saponins","display_name":"triterpenoid saponins","score":0.847000002861023},{"id":"https://openalex.org/keywords/gypsogenin","display_name":"gypsogenin","score":0.9210000038146973},{"id":"https://openalex.org/keywords/quillaic-acid","display_name":"quillaic acid","score":0.9959999918937683},{"id":"https://openalex.org/keywords/root-extract","display_name":"root extract","score":0.5},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.7580000162124634},{"id":"https://openalex.org/keywords/anthelmintic-activity","display_name":"anthelmintic activity","score":1.0},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9959999918937683},{"id":"https://openalex.org/keywords/ccrf-cem-cells","display_name":"CCRF-CEM cells","score":0.9229999780654907},{"id":"https://openalex.org/keywords/caryophyllaceae","display_name":"Caryophyllaceae","score":0.8659999966621399}],"concepts":[{"id":"https://openalex.org/C2780527577","wikidata":"https://www.wikidata.org/wiki/Q2915788","display_name":"Triterpene","level":3,"score":0.8803309202194214},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.668230414390564},{"id":"https://openalex.org/C2781394091","wikidata":"https://www.wikidata.org/wiki/Q25995","display_name":"Caryophyllaceae","level":2,"score":0.6516268253326416},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6193991303443909},{"id":"https://openalex.org/C2781144210","wikidata":"https://www.wikidata.org/wiki/Q172275","display_name":"Chloroform","level":2,"score":0.5289029479026794},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4903164207935333},{"id":"https://openalex.org/C44937612","wikidata":"https://www.wikidata.org/wiki/Q212364","display_name":"Terpene","level":2,"score":0.48040083050727844},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.44654396176338196},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.4421892762184143},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.4400434195995331},{"id":"https://openalex.org/C2779607525","wikidata":"https://www.wikidata.org/wiki/Q14982","display_name":"Methanol","level":2,"score":0.4260200560092926},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.2322159707546234},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.22153499722480774},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19855165481567383},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.179656982421875},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1525108516216278},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.07975804805755615},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000871","descriptor_name":"Anthelmintics","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000871","descriptor_name":"Anthelmintics","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006027","descriptor_name":"Glycosides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006027","descriptor_name":"Glycosides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012503","descriptor_name":"Saponins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012503","descriptor_name":"Saponins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018517","descriptor_name":"Plant Roots","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D029748","descriptor_name":"Caryophyllaceae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053719","descriptor_name":"Tandem Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1080/14786419.2023.2260068","doi":"https://doi.org/10.1080/14786419.2023.2260068","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14786419.2023.2260068","pdf_url":null,"source":{"id":"https://openalex.org/S205999849","display_name":"Natural Product Research","issn_l":"1478-6419","issn":["1478-6419","1478-6427"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural Product Research","raw_type":"journal-article"},{"id":"pmid:37740590","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37740590","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural product research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1175529170","https://openalex.org/W1494211647","https://openalex.org/W1852359153","https://openalex.org/W1973107801","https://openalex.org/W2006251450","https://openalex.org/W2017706819","https://openalex.org/W2020123228","https://openalex.org/W2045978463","https://openalex.org/W2063519407","https://openalex.org/W2092161504","https://openalex.org/W2163089151","https://openalex.org/W2333831944","https://openalex.org/W2908603571","https://openalex.org/W3024738743","https://openalex.org/W4247725404","https://openalex.org/W4321787459","https://openalex.org/W4366416266"],"related_works":["https://openalex.org/W6976745105","https://openalex.org/W6967700780","https://openalex.org/W2779768394","https://openalex.org/W3016230553","https://openalex.org/W4387496186","https://openalex.org/W4389150305","https://openalex.org/W2771759499","https://openalex.org/W2075904106","https://openalex.org/W2318878285","https://openalex.org/W2914893134"],"abstract_inverted_index":{"A":[0],"crude":[1],"methanol":[2,56],"extract":[3,75],"of":[4,7,18,31,60,80,91],"the":[5,15,29,48,70,73,77],"roots":[6],"Allochrusa":[8],"gypsophiloides":[9,62],"(syn.":[10],"Acanthophyllum":[11],"gypsophiloides)":[12],"(collected":[13],"from":[14,37],"Tashkent":[16],"region":[17],"Uzbekistan)":[19],"was":[20],"chemically":[21],"characterised":[22],"by":[23],"UHPLC-ESI-QTOF-MS/MS":[24],"analysis.":[25],"The":[26,54],"results":[27],"indicate":[28],"presence":[30],"six":[32],"major":[33],"bisdesmosidic":[34],"saponins":[35],"derived":[36],"gypsogenin,":[38],"gypsogenic":[39],"and":[40,57,66,84,93],"quillaic":[41],"acids,":[42],"including":[43],"five":[44],"compounds":[45],"reported":[46],"for":[47,51],"first":[49],"time":[50],"this":[52],"species.":[53],"chloroform,":[55],"water":[58,74],"extracts":[59],"A.":[61],"showed":[63],"weak":[64],"antioxidant":[65],"anthelmintic":[67],"activities.":[68],"Among":[69],"tested":[71],"extracts,":[72],"exhibited":[76],"highest":[78],"level":[79],"cytotoxicity":[81],"in":[82],"CCRF-CEM":[83],"CEM/ADR5000":[85],"cell":[86],"lines":[87],"with":[88],"IC50":[89],"values":[90],"23.6":[92],"31.9":[94],"\u00b5g/mL,":[95],"respectively.":[96]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-09-24T00:00:00"}