{"id":"https://openalex.org/W4386968634","doi":"https://doi.org/10.1016/j.gene.2023.147824","title":"Genetic variants and effect modifiers of QT interval prolongation in patients with sickle cell disease","display_name":"Genetic variants and effect modifiers of QT interval prolongation in patients with sickle cell disease","publication_year":2023,"publication_date":"2023-09-22","ids":{"openalex":"https://openalex.org/W4386968634","doi":"https://doi.org/10.1016/j.gene.2023.147824","pmid":"https://pubmed.ncbi.nlm.nih.gov/37741592"},"language":"en","primary_location":{"id":"doi:10.1016/j.gene.2023.147824","doi":"https://doi.org/10.1016/j.gene.2023.147824","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.gene.2023.147824","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049376943","display_name":"Mengna Zhang","orcid":"https://orcid.org/0000-0001-6991-7712","observed_orcids":["https://orcid.org/0000-0001-6991-7712"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mengna Zhang","raw_affiliation_strings":["Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA","Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA"],"raw_orcid":"https://orcid.org/0000-0001-6991-7712","affiliations":[{"raw_affiliation_string":"Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025199072","display_name":"William B. Hillegass","orcid":"https://orcid.org/0000-0001-6428-0564","observed_orcids":["https://orcid.org/0000-0001-6428-0564"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William B. Hillegass","raw_affiliation_strings":["Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA","Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA"],"raw_orcid":"https://orcid.org/0000-0001-6428-0564","affiliations":[{"raw_affiliation_string":"Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xue Yu","orcid":"https://orcid.org/0000-0002-6051-3241","observed_orcids":["https://orcid.org/0000-0002-6051-3241"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xue Yu","raw_affiliation_strings":["Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA","Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA"],"raw_orcid":"https://orcid.org/0000-0002-6051-3241","affiliations":[{"raw_affiliation_string":"Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049404381","display_name":"Suvankar Majumdar","orcid":"https://orcid.org/0000-0003-1471-738X","observed_orcids":["https://orcid.org/0000-0003-1471-738X"]},"institutions":[{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suvankar Majumdar","raw_affiliation_strings":["Division of Hematology, Children's National Hospital, Washington, DC, USA"],"raw_orcid":"https://orcid.org/0000-0003-1471-738X","affiliations":[{"raw_affiliation_string":"Division of Hematology, Children's National Hospital, Washington, DC, USA","institution_ids":["https://openalex.org/I1336742384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072179706","display_name":"James D. Pollard","orcid":"https://orcid.org/0000-0001-5359-2861","observed_orcids":["https://orcid.org/0000-0001-5359-2861"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Daryl Pollard","raw_affiliation_strings":["Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Erin Jackson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erin Jackson","raw_affiliation_strings":["Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS 39216, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037087824","display_name":"Jarrod D. Knudson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jarrod Knudson","raw_affiliation_strings":["Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS 39216, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027822736","display_name":"Douglas A. Wolfe","orcid":"https://orcid.org/0000-0002-3446-8002","observed_orcids":["https://orcid.org/0000-0002-3446-8002"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Douglas Wolfe","raw_affiliation_strings":["Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA"],"raw_orcid":"https://orcid.org/0000-0002-3446-8002","affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066832003","display_name":"Gregory James Kato","orcid":"https://orcid.org/0000-0003-4465-3217","observed_orcids":["https://orcid.org/0000-0003-4465-3217"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory J. Kato","raw_affiliation_strings":["Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA"],"raw_orcid":"https://orcid.org/0000-0003-4465-3217","affiliations":[{"raw_affiliation_string":"Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102839223","display_name":"Joseph Maher","orcid":"https://orcid.org/0000-0003-2515-9600","observed_orcids":["https://orcid.org/0000-0003-2515-9600"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joseph F. Maher","raw_affiliation_strings":["Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Internal Medicine/Cancer Genetics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA. Electronic address: joseph.maher@va.gov","Department of Internal Medicine/Cancer Genetics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA","Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA"],"raw_orcid":"https://orcid.org/0000-0003-2515-9600","affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Internal Medicine/Cancer Genetics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA. Electronic address: joseph.maher@va.gov","institution_ids":["https://openalex.org/I1292894508","https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department of Internal Medicine/Cancer Genetics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010904842","display_name":"Hao Mei","orcid":"https://orcid.org/0000-0002-0125-7153","observed_orcids":["https://orcid.org/0000-0002-0125-7153","https://orcid.org/0000-0002-0878-4431"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hao Mei","raw_affiliation_strings":["Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA. Electronic address: hmei@umc.edu","Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA","Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA; Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA. Electronic address: hmei@umc.edu","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department of Data Science, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA","institution_ids":["https://openalex.org/I29606459"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5010904842","https://openalex.org/A5102839223"],"corresponding_institution_ids":["https://openalex.org/I1292894508","https://openalex.org/I29606459"],"apc_list":{"value":2940,"currency":"USD","value_usd":2940},"apc_paid":null,"fwci":0.1725,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.49596056,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"890","issue":null,"first_page":"147824","last_page":"147824"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.5522000193595886,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.5522000193595886,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.3781999945640564,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.051500000059604645,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sickle-cell-disease","display_name":"sickle cell disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/qt-interval-prolongation","display_name":"QT prolongation","score":0.9430000185966492},{"id":"https://openalex.org/keywords/qtc-interval","display_name":"QTc interval","score":0.7149999737739563},{"id":"https://openalex.org/keywords/polygenic-risk-score","display_name":"polygenic risk score","score":0.859000027179718},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9100000262260437},{"id":"https://openalex.org/keywords/effect-modifiers","display_name":"effect modifiers","score":0.6039999723434448},{"id":"https://openalex.org/keywords/serum-alanine-transaminase","display_name":"serum alanine transaminase","score":0.9710000157356262},{"id":"https://openalex.org/keywords/liver-disease","display_name":"liver disease","score":0.8330000042915344},{"id":"https://openalex.org/keywords/sudden-cardiac-death","display_name":"sudden cardiac death","score":0.8799999952316284},{"id":"https://openalex.org/keywords/cps1","display_name":"CPS1","score":0.574999988079071},{"id":"https://openalex.org/keywords/nos1ap","display_name":"NOS1AP","score":0.9940000176429749},{"id":"https://openalex.org/keywords/african-americans","display_name":"African Americans","score":0.6949999928474426},{"id":"https://openalex.org/keywords/genetic-risk-variants","display_name":"genetic risk variants","score":0.5979999899864197},{"id":"https://openalex.org/keywords/qrs-duration","display_name":"QRS duration","score":0.640999972820282},{"id":"https://openalex.org/keywords/recessive-model","display_name":"recessive model","score":0.6610000133514404},{"id":"https://openalex.org/keywords/additive-models","display_name":"additive models","score":0.9409999847412109},{"id":"https://openalex.org/keywords/stratified-analysis","display_name":"stratified analysis","score":0.6380000114440918},{"id":"https://openalex.org/keywords/cardiac-arrhythmia","display_name":"cardiac arrhythmias","score":0.5070000290870667}],"concepts":[{"id":"https://openalex.org/C118441451","wikidata":"https://www.wikidata.org/wiki/Q12074763","display_name":"QT interval","level":2,"score":0.8857315182685852},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.6393148303031921},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5784223675727844},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.46621352434158325},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4417960047721863},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3879912495613098},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3450556993484497},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.25477033853530884},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19095921516418457},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.059159427881240845},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000755","descriptor_name":"Anemia, Sickle Cell","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008133","descriptor_name":"Long QT Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016757","descriptor_name":"Death, Sudden, Cardiac","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D048868","descriptor_name":"Adaptor Proteins, Signal Transducing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.gene.2023.147824","doi":"https://doi.org/10.1016/j.gene.2023.147824","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.gene.2023.147824","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},{"id":"pmid:37741592","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37741592","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W156488416","https://openalex.org/W597511998","https://openalex.org/W1966545771","https://openalex.org/W1972937788","https://openalex.org/W1978128234","https://openalex.org/W1982275158","https://openalex.org/W1984224132","https://openalex.org/W1984518423","https://openalex.org/W1985891903","https://openalex.org/W1990995432","https://openalex.org/W2000129904","https://openalex.org/W2001438420","https://openalex.org/W2018301429","https://openalex.org/W2021950130","https://openalex.org/W2022617607","https://openalex.org/W2046700956","https://openalex.org/W2053495832","https://openalex.org/W2054903745","https://openalex.org/W2069353545","https://openalex.org/W2074519955","https://openalex.org/W2097508272","https://openalex.org/W2098582760","https://openalex.org/W2099085143","https://openalex.org/W2109625917","https://openalex.org/W2121153631","https://openalex.org/W2125955136","https://openalex.org/W2132199634","https://openalex.org/W2133662129","https://openalex.org/W2136815580","https://openalex.org/W2164634947","https://openalex.org/W2222845006","https://openalex.org/W2284531888","https://openalex.org/W2319036533","https://openalex.org/W2334263927","https://openalex.org/W2430793815","https://openalex.org/W2516751723","https://openalex.org/W2530666734","https://openalex.org/W2613494736","https://openalex.org/W2749932904","https://openalex.org/W2762919016","https://openalex.org/W2774478771","https://openalex.org/W2785950214","https://openalex.org/W2801251616","https://openalex.org/W2945425566","https://openalex.org/W2971950481","https://openalex.org/W3005736019","https://openalex.org/W3014608529","https://openalex.org/W3028329270","https://openalex.org/W3038799789","https://openalex.org/W3206489460","https://openalex.org/W4210449137","https://openalex.org/W4210833727","https://openalex.org/W4214749091","https://openalex.org/W4214870539","https://openalex.org/W4283837991","https://openalex.org/W4286224631","https://openalex.org/W4380366138","https://openalex.org/W6793163677"],"related_works":["https://openalex.org/W4380366138","https://openalex.org/W1982275158","https://openalex.org/W2555461543","https://openalex.org/W1990995432","https://openalex.org/W2558348979","https://openalex.org/W2168968191","https://openalex.org/W2561278735","https://openalex.org/W4413763108","https://openalex.org/W4417016122","https://openalex.org/W7215650399"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-09-23T00:00:00"}