{"id":"https://openalex.org/W4386944771","doi":"https://doi.org/10.1111/liv.15736","title":"Ursodeoxycholic acid does not affect the clinical outcome of SARS\u2010CoV\u20102 infection: A retrospective study of propensity score\u2010matched cohorts","display_name":"Ursodeoxycholic acid does not affect the clinical outcome of SARS\u2010CoV\u20102 infection: A retrospective study of propensity score\u2010matched cohorts","publication_year":2023,"publication_date":"2023-09-21","ids":{"openalex":"https://openalex.org/W4386944771","doi":"https://doi.org/10.1111/liv.15736","pmid":"https://pubmed.ncbi.nlm.nih.gov/37735968"},"language":"en","primary_location":{"id":"doi:10.1111/liv.15736","doi":"https://doi.org/10.1111/liv.15736","is_oa":true,"landing_page_url":"https://doi.org/10.1111/liv.15736","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/liv.15736","source":{"id":"https://openalex.org/S206392846","display_name":"Liver International","issn_l":"0106-9543","issn":["0106-9543","1478-3223","1478-3231","1600-0676"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Liver International","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/liv.15736","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040416149","display_name":"Giuseppe Marrone","orcid":"https://orcid.org/0000-0002-9475-3948","observed_orcids":["https://orcid.org/0000-0002-9475-3948"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Giuseppe Marrone","raw_affiliation_strings":["Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"],"raw_orcid":"https://orcid.org/0000-0002-9475-3948","affiliations":[{"raw_affiliation_string":"Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059315688","display_name":"Marcello Covino","orcid":"https://orcid.org/0000-0001-9916-9372","observed_orcids":["https://orcid.org/0000-0001-9916-9372"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marcello Covino","raw_affiliation_strings":["Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"],"raw_orcid":"https://orcid.org/0000-0001-9916-9372","affiliations":[{"raw_affiliation_string":"Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018162761","display_name":"Giuseppe Merra","orcid":"https://orcid.org/0000-0003-4753-3528","observed_orcids":["https://orcid.org/0000-0003-4753-3528"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Merra","raw_affiliation_strings":["Department of Biomedicine and Prevention Universit\u00e0 degli Studi di Roma Tor Vergata  Rome Italy"],"raw_orcid":"https://orcid.org/0000-0003-4753-3528","affiliations":[{"raw_affiliation_string":"Department of Biomedicine and Prevention Universit\u00e0 degli Studi di Roma Tor Vergata  Rome Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057440645","display_name":"Andrea Piccioni","orcid":"https://orcid.org/0000-0001-5703-8737","observed_orcids":["https://orcid.org/0000-0001-5703-8737"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Piccioni","raw_affiliation_strings":["Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"],"raw_orcid":"https://orcid.org/0000-0001-5703-8737","affiliations":[{"raw_affiliation_string":"Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102988821","display_name":"Annamaria Amodeo","orcid":"https://orcid.org/0009-0007-5539-0789","observed_orcids":["https://orcid.org/0009-0007-5539-0789"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Annamaria Amodeo","raw_affiliation_strings":["Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"],"raw_orcid":"https://orcid.org/0009-0007-5539-0789","affiliations":[{"raw_affiliation_string":"Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041978159","display_name":"Angela Novelli","orcid":"https://orcid.org/0009-0000-9202-6512","observed_orcids":["https://orcid.org/0009-0000-9202-6512"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Angela Novelli","raw_affiliation_strings":["Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"],"raw_orcid":"https://orcid.org/0009-0000-9202-6512","affiliations":[{"raw_affiliation_string":"Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049899886","display_name":"Rita Murri","orcid":"https://orcid.org/0000-0001-9468-5458","observed_orcids":["https://orcid.org/0000-0001-9468-5458"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rita Murri","raw_affiliation_strings":["Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"],"raw_orcid":"https://orcid.org/0000-0001-9468-5458","affiliations":[{"raw_affiliation_string":"Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076471646","display_name":"Maurizio Pompili","orcid":"https://orcid.org/0000-0001-6699-7980","observed_orcids":["https://orcid.org/0000-0001-6699-7980"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maurizio Pompili","raw_affiliation_strings":["Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"],"raw_orcid":"https://orcid.org/0000-0001-6699-7980","affiliations":[{"raw_affiliation_string":"Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Antonio Gasbarrini","orcid":"https://orcid.org/0000-0003-4863-6924","observed_orcids":["https://orcid.org/0000-0003-4863-6924"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Gasbarrini","raw_affiliation_strings":["Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"],"raw_orcid":"https://orcid.org/0000-0003-4863-6924","affiliations":[{"raw_affiliation_string":"Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103011293","display_name":"Francesco Franceschi","orcid":"https://orcid.org/0000-0001-6266-445X","observed_orcids":["https://orcid.org/0000-0001-6266-445X"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesco Franceschi","raw_affiliation_strings":["Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"],"raw_orcid":"https://orcid.org/0000-0001-6266-445X","affiliations":[{"raw_affiliation_string":"Medical and Surgical Abdominal and Endocrine Metabolic Sciences AND Emergency, Anesthesiology and Resuscitation Departements, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy","institution_ids":["https://openalex.org/I103320735"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5040416149"],"corresponding_institution_ids":["https://openalex.org/I103320735","https://openalex.org/I2802557943","https://openalex.org/I4210153126"],"apc_list":{"value":4740,"currency":"USD","value_usd":4740},"apc_paid":{"value":4740,"currency":"USD","value_usd":4740},"fwci":2.6963,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.89772572,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"44","issue":"1","first_page":"83","last_page":"92"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11296","display_name":"COVID-19 and healthcare impacts","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ursodeoxycholic-acid","display_name":"ursodeoxycholic acid","score":1.0},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9419999718666077},{"id":"https://openalex.org/keywords/ace2-receptor","display_name":"ACE2 receptor","score":0.8100000023841858},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.6489999890327454},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.3630000054836273},{"id":"https://openalex.org/keywords/predictors-of-death","display_name":"predictors of death","score":0.7850000262260437},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.9269999861717224},{"id":"https://openalex.org/keywords/national-early-warning-score","display_name":"National Early Warning Score","score":0.8159999847412109},{"id":"https://openalex.org/keywords/charlson-comorbidity-index","display_name":"Charlson Comorbidity Index","score":0.9440000057220459},{"id":"https://openalex.org/keywords/emergency-department-patients","display_name":"emergency department patients","score":0.40700000524520874}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8436151146888733},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7681057453155518},{"id":"https://openalex.org/C2780965833","wikidata":"https://www.wikidata.org/wiki/Q241374","display_name":"Ursodeoxycholic acid","level":2,"score":0.7408983707427979},{"id":"https://openalex.org/C17923572","wikidata":"https://www.wikidata.org/wiki/Q7250160","display_name":"Propensity score matching","level":2,"score":0.6817894577980042},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5515824556350708},{"id":"https://openalex.org/C144301174","wikidata":"https://www.wikidata.org/wiki/Q7893852","display_name":"Univariate analysis","level":3,"score":0.520297110080719},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5011515617370605},{"id":"https://openalex.org/C66339696","wikidata":"https://www.wikidata.org/wiki/Q6089397","display_name":"Log-rank test","level":3,"score":0.466613233089447},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.46421507000923157},{"id":"https://openalex.org/C2778314733","wikidata":"https://www.wikidata.org/wiki/Q6639737","display_name":"Pneumonia severity index","level":4,"score":0.4639745354652405},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.39003878831863403},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.33875590562820435},{"id":"https://openalex.org/C2776102371","wikidata":"https://www.wikidata.org/wiki/Q460030","display_name":"Community-acquired pneumonia","level":3,"score":0.2737749516963959}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014580","descriptor_name":"Ursodeoxycholic Acid","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D057216","descriptor_name":"Propensity Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1111/liv.15736","doi":"https://doi.org/10.1111/liv.15736","is_oa":true,"landing_page_url":"https://doi.org/10.1111/liv.15736","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/liv.15736","source":{"id":"https://openalex.org/S206392846","display_name":"Liver International","issn_l":"0106-9543","issn":["0106-9543","1478-3223","1478-3231","1600-0676"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Liver International","raw_type":"journal-article"},{"id":"pmid:37735968","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37735968","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Liver international : official journal of the International Association for the Study of the Liver","raw_type":"Journal Article"},{"id":"pmh:oai:art.torvergata.it:2108/359146","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2108/359146","pdf_url":null,"source":{"id":"https://openalex.org/S4306400993","display_name":"Cineca Institutional Research Information System (Tor Vergata University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I116067653","host_organization_name":"University of Rome Tor Vergata","host_organization_lineage":["https://openalex.org/I116067653"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:publicatt.unicatt.it:10807/273382","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10807/273382","pdf_url":null,"source":{"id":"https://openalex.org/S4306400564","display_name":"PubliCatt (Universit\u00e0 Cattolica del Sacro Cuore)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1111/liv.15736","doi":"https://doi.org/10.1111/liv.15736","is_oa":true,"landing_page_url":"https://doi.org/10.1111/liv.15736","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/liv.15736","source":{"id":"https://openalex.org/S206392846","display_name":"Liver International","issn_l":"0106-9543","issn":["0106-9543","1478-3223","1478-3231","1600-0676"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Liver International","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386944771.pdf","grobid_xml":"https://content.openalex.org/works/W4386944771.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W2000445173","https://openalex.org/W2150979970","https://openalex.org/W2572174115","https://openalex.org/W2593095365","https://openalex.org/W2605729742","https://openalex.org/W2794306199","https://openalex.org/W2900599929","https://openalex.org/W2962982198","https://openalex.org/W3004280078","https://openalex.org/W3009912996","https://openalex.org/W3012455685","https://openalex.org/W3024080795","https://openalex.org/W3027630905","https://openalex.org/W3043722389","https://openalex.org/W3047144258","https://openalex.org/W3080747588","https://openalex.org/W3081988469","https://openalex.org/W3087362748","https://openalex.org/W3089697169","https://openalex.org/W3090929175","https://openalex.org/W3096019639","https://openalex.org/W3106878713","https://openalex.org/W3111255098","https://openalex.org/W3113195742","https://openalex.org/W3137551872","https://openalex.org/W3155756133","https://openalex.org/W3188143357","https://openalex.org/W3212583014","https://openalex.org/W4200117665","https://openalex.org/W4200206478","https://openalex.org/W4200543103","https://openalex.org/W4224324731","https://openalex.org/W4281763105","https://openalex.org/W4306880067","https://openalex.org/W4307864051","https://openalex.org/W4309700938","https://openalex.org/W4310774393","https://openalex.org/W4311493259","https://openalex.org/W4317708656","https://openalex.org/W4321435546","https://openalex.org/W4322491825","https://openalex.org/W4322628656","https://openalex.org/W4323294549","https://openalex.org/W4360871696","https://openalex.org/W4361272012","https://openalex.org/W4362601225","https://openalex.org/W4385811042"],"related_works":["https://openalex.org/W4385811042","https://openalex.org/W7153455094","https://openalex.org/W7122414573","https://openalex.org/W4401589030","https://openalex.org/W4389686938","https://openalex.org/W6939647818","https://openalex.org/W4407022503","https://openalex.org/W4368404798","https://openalex.org/W4362601225","https://openalex.org/W4404513888"],"abstract_inverted_index":{"BACKGROUND:":[0],"Ursodeoxycholic":[1],"acid":[2],"(UDCA)":[3],"has":[4],"been":[5],"recently":[6],"proposed":[7],"as":[8],"a":[9,211],"modulator":[10],"of":[11,35,56,79,170,187,205,213,234],"angiotensin-converting":[12],"enzyme":[13],"2":[14],"(ACE2)":[15],"receptor":[16],"expression,":[17],"with":[18,46,89],"potential":[19],"effects":[20,230],"on":[21,81,231],"COVID-19.":[22,235],"AIM":[23],"AND":[24],"STUDY":[25],"DESIGN:":[26],"We":[27],"retrospectively":[28],"evaluated":[29],"the":[30,41,52,57,77,94,118,122,129,143,150,168,232],"clinical":[31],"course":[32],"and":[33,54,61,70,126,146,178,197,218,248],"outcome":[34,55,233],"subjects":[36,63,88,107,114,137],"taking":[37,109],"UDCA":[38,80,124,130,151,207,222],"admitted":[39,92],"to":[40,75,93,102,227,242],"hospital":[42],"for":[43],"COVID-19":[44,91],"compared":[45],"matched":[47,134],"infected":[48],"subjects.":[49],"Differences":[50],"regarding":[51],"severity":[53],"disease":[58],"between":[59,162],"treated":[60],"non-treated":[62],"were":[64,73,108,115,183,200],"assessed.":[65],"The":[66,153],"Kaplan-Meier":[67,154],"survival":[68,161,214],"analysis":[69,155],"log-rank":[71],"test":[72],"used":[74],"evaluate":[76,243],"effect":[78],"all-cause":[82],"intra-hospital":[83],"mortality.":[84],"RESULTS:":[85],"Among":[86],"6444":[87],"confirmed":[90,201],"emergency":[95],"department":[96],"(ED)":[97],"from":[98],"1":[99],"March":[100],"2020":[101],"31":[103],"December":[104],"2022,":[105],"109":[106],"UDCA.":[110],"After":[111],"matching":[112],"629":[113],"included":[116],"in":[117,121,128,142,149,160,216,245],"study:":[119],"521":[120],"no":[123,157],"group":[125,145],"108":[127],"group.":[131,152],"In":[132,164],"our":[133],"cohort,":[135],"144":[136],"(22.9%)":[138],"died,":[139],"118":[140],"(22.6%)":[141],"no-UDCA":[144],"26":[147],"(24.1%)":[148],"showed":[156],"significant":[158,184,202,229],"difference":[159],"groups.":[163],"univariate":[165,217],"regression":[166,192],"analysis,":[167,193],"presence":[169],"pneumonia,":[171],"National":[172],"Early":[173],"Warning":[174],"Score":[175],"(NEWS)":[176],"score,":[177],"Charlson":[179],"Comorbidity":[180],"Index":[181],"(CCI)":[182],"independent":[185,203],"predictors":[186,204],"death.":[188,206],"At":[189],"multivariate":[190,219],"Cox":[191],"age,":[194],"NEWS,":[195],"pneumonia":[196],"CCI":[198],"index":[199],"treatment":[208,223],"was":[209],"not":[210,225],"predictor":[212],"both":[215],"regressions.":[220],"CONCLUSIONS:":[221],"does":[224],"appear":[226],"have":[228],"Specially":[236],"designed":[237],"prospective":[238],"studies":[239],"are":[240],"needed":[241],"efficacy":[244],"preventing":[246],"infection":[247],"severe":[249],"disease.":[250]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":9}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-09-23T00:00:00"}