{"id":"https://openalex.org/W4386860181","doi":"https://doi.org/10.3389/fphar.2023.1249418","title":"Protective effects of curcumin against osteoporosis and its molecular mechanisms: a recent review in preclinical trials","display_name":"Protective effects of curcumin against osteoporosis and its molecular mechanisms: a recent review in preclinical trials","publication_year":2023,"publication_date":"2023-09-18","ids":{"openalex":"https://openalex.org/W4386860181","doi":"https://doi.org/10.3389/fphar.2023.1249418","pmid":"https://pubmed.ncbi.nlm.nih.gov/37790808","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10544586"},"language":"en","primary_location":{"id":"doi:10.3389/fphar.2023.1249418","doi":"https://doi.org/10.3389/fphar.2023.1249418","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphar.2023.1249418","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphar.2023.1249418/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S132108250","display_name":"Frontiers in Pharmacology","issn_l":"1663-9812","issn":["1663-9812"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pharmacology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fphar.2023.1249418/pdf?isPublishedV2=False","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000658242","display_name":"Shenglei Yang","orcid":"https://orcid.org/0009-0002-3236-5218","observed_orcids":["https://orcid.org/0009-0002-3236-5218"]},"institutions":[{"id":"https://openalex.org/I4210158810","display_name":"Shenyang Sport University","ror":"https://ror.org/05kz0b404","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210158810"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shenglei Yang","raw_affiliation_strings":["College of Exercise and Health, Shenyang Sport University, Shenyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Exercise and Health, Shenyang Sport University, Shenyang, China","institution_ids":["https://openalex.org/I4210158810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100576521","display_name":"Yuying Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I134841294","display_name":"Binzhou Medical University","ror":"https://ror.org/008w1vb37","country_code":"CN","type":"education","lineage":["https://openalex.org/I134841294"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuying Sun","raw_affiliation_strings":["School of Stomatology, Binzhou Medical College, Yantai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Stomatology, Binzhou Medical College, Yantai, China","institution_ids":["https://openalex.org/I134841294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058775249","display_name":"\u041b. \u0412. \u041a\u0430\u043f\u0438\u043b\u0435\u0432\u0438\u0447","orcid":"https://orcid.org/0000-0002-2316-576X","observed_orcids":["https://orcid.org/0000-0002-2316-576X"]},"institutions":[{"id":"https://openalex.org/I196355604","display_name":"National Research Tomsk State University","ror":"https://ror.org/02he2nc27","country_code":"RU","type":"education","lineage":["https://openalex.org/I196355604"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Leonid Kapilevich","raw_affiliation_strings":["Faculty of Physical Education, N\u0430tion\u0430l Rese\u0430rch Tomsk St\u0430te University, Tomsk, Russi\u0430"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Physical Education, N\u0430tion\u0430l Rese\u0430rch Tomsk St\u0430te University, Tomsk, Russi\u0430","institution_ids":["https://openalex.org/I196355604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100365328","display_name":"Xinan Zhang","orcid":"https://orcid.org/0000-0002-7854-4134","observed_orcids":["https://orcid.org/0000-0002-7854-4134"]},"institutions":[{"id":"https://openalex.org/I4210158810","display_name":"Shenyang Sport University","ror":"https://ror.org/05kz0b404","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210158810"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xin\u2019an Zhang","raw_affiliation_strings":["College of Exercise and Health, Shenyang Sport University, Shenyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Exercise and Health, Shenyang Sport University, Shenyang, China","institution_ids":["https://openalex.org/I4210158810"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111234736","display_name":"Yue Huang","orcid":"https://orcid.org/0009-0007-7291-5866","observed_orcids":["https://orcid.org/0009-0007-7291-5866"]},"institutions":[{"id":"https://openalex.org/I4210158810","display_name":"Shenyang Sport University","ror":"https://ror.org/05kz0b404","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210158810"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yue Huang","raw_affiliation_strings":["College of Exercise and Health, Shenyang Sport University, Shenyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Exercise and Health, Shenyang Sport University, Shenyang, China","institution_ids":["https://openalex.org/I4210158810"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100365328","https://openalex.org/A5111234736"],"corresponding_institution_ids":["https://openalex.org/I4210158810"],"apc_list":{"value":3295,"currency":"USD","value_usd":3295},"apc_paid":{"value":3295,"currency":"USD","value_usd":3295},"fwci":1.2293,"has_fulltext":true,"cited_by_count":52,"citation_normalized_percentile":{"value":0.77514793,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"14","issue":null,"first_page":"1249418","last_page":"1249418"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.9315999746322632,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.9315999746322632,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.03449999913573265,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14331","display_name":"Medicinal Plant Pharmacodynamics Research","score":0.01940000057220459,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/curcumin","display_name":"curcumin","score":1.0},{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":1.0},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.7730000019073486},{"id":"https://openalex.org/keywords/bone-microarchitecture","display_name":"bone microarchitecture","score":0.8339999914169312},{"id":"https://openalex.org/keywords/fracture-risk","display_name":"fracture risk","score":0.8970000147819519},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.6050000190734863},{"id":"https://openalex.org/keywords/anti-apoptotic-effects","display_name":"anti-apoptotic effects","score":0.8899999856948853},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.9959999918937683},{"id":"https://openalex.org/keywords/natural-phenolic-compounds","display_name":"natural phenolic compounds","score":0.8790000081062317},{"id":"https://openalex.org/keywords/alternative-medicine","display_name":"complementary and alternative medicine","score":0.8420000076293945},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.7749999761581421},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.4970000088214874}],"concepts":[{"id":"https://openalex.org/C2778250585","wikidata":"https://www.wikidata.org/wiki/Q312266","display_name":"Curcumin","level":2,"score":0.9251376390457153},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.8923045992851257},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7988385558128357},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5651979446411133},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5134185552597046},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4833352267742157},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4373754560947418},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25349122285842896},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0822584331035614}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fphar.2023.1249418","doi":"https://doi.org/10.3389/fphar.2023.1249418","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphar.2023.1249418","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphar.2023.1249418/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S132108250","display_name":"Frontiers in Pharmacology","issn_l":"1663-9812","issn":["1663-9812"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pharmacology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10544586","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10544586","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10544586/pdf/fphar-14-1249418.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Pharmacol","raw_type":"Text"},{"id":"pmid:37790808","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37790808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in pharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:0afb503f4cbe4871a1cb14ccc6808c02","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/0afb503f4cbe4871a1cb14ccc6808c02","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Pharmacology, Vol 14 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fphar.2023.1249418","doi":"https://doi.org/10.3389/fphar.2023.1249418","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphar.2023.1249418","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphar.2023.1249418/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S132108250","display_name":"Frontiers in Pharmacology","issn_l":"1663-9812","issn":["1663-9812"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pharmacology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5487089148","display_name":null,"funder_award_id":"32371184","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386860181.pdf","grobid_xml":"https://content.openalex.org/works/W4386860181.grobid-xml"},"referenced_works_count":143,"referenced_works":["https://openalex.org/W37344990","https://openalex.org/W233193461","https://openalex.org/W260135859","https://openalex.org/W1144202826","https://openalex.org/W1732425222","https://openalex.org/W1876124517","https://openalex.org/W1966362154","https://openalex.org/W1967012185","https://openalex.org/W1970242947","https://openalex.org/W1971282735","https://openalex.org/W1972179974","https://openalex.org/W1972328688","https://openalex.org/W1994596418","https://openalex.org/W2000902284","https://openalex.org/W2002315967","https://openalex.org/W2004334938","https://openalex.org/W2015414776","https://openalex.org/W2016201042","https://openalex.org/W2018602999","https://openalex.org/W2018723605","https://openalex.org/W2026885538","https://openalex.org/W2030172376","https://openalex.org/W2037154438","https://openalex.org/W2041420220","https://openalex.org/W2042618296","https://openalex.org/W2045808113","https://openalex.org/W2045906656","https://openalex.org/W2053374578","https://openalex.org/W2053516334","https://openalex.org/W2055288043","https://openalex.org/W2059413260","https://openalex.org/W2060165569","https://openalex.org/W2062447638","https://openalex.org/W2063013768","https://openalex.org/W2065084683","https://openalex.org/W2065812833","https://openalex.org/W2075097911","https://openalex.org/W2077164311","https://openalex.org/W2079088633","https://openalex.org/W2083519207","https://openalex.org/W2088657362","https://openalex.org/W2094563087","https://openalex.org/W2095703370","https://openalex.org/W2103454592","https://openalex.org/W2108918650","https://openalex.org/W2119682748","https://openalex.org/W2123346255","https://openalex.org/W2124273389","https://openalex.org/W2124413381","https://openalex.org/W2134578689","https://openalex.org/W2136370256","https://openalex.org/W2138889138","https://openalex.org/W2141610037","https://openalex.org/W2150418339","https://openalex.org/W2152412984","https://openalex.org/W2153101639","https://openalex.org/W2154049977","https://openalex.org/W2157975994","https://openalex.org/W2158204493","https://openalex.org/W2160856601","https://openalex.org/W2169972304","https://openalex.org/W2196300506","https://openalex.org/W2197589690","https://openalex.org/W2234844573","https://openalex.org/W2276241585","https://openalex.org/W2317541348","https://openalex.org/W2327974216","https://openalex.org/W2332920232","https://openalex.org/W2404811836","https://openalex.org/W2414906782","https://openalex.org/W2537847946","https://openalex.org/W2552658430","https://openalex.org/W2560057190","https://openalex.org/W2578920087","https://openalex.org/W2579340176","https://openalex.org/W2586409573","https://openalex.org/W2586496902","https://openalex.org/W2600338350","https://openalex.org/W2606406447","https://openalex.org/W2728830401","https://openalex.org/W2732630371","https://openalex.org/W2760791930","https://openalex.org/W2766083858","https://openalex.org/W2766194321","https://openalex.org/W2790044190","https://openalex.org/W2790238124","https://openalex.org/W2795126008","https://openalex.org/W2803419435","https://openalex.org/W2804149502","https://openalex.org/W2807629723","https://openalex.org/W2883383944","https://openalex.org/W2886521864","https://openalex.org/W2888230285","https://openalex.org/W2902109723","https://openalex.org/W2911852956","https://openalex.org/W2913757269","https://openalex.org/W2915244548","https://openalex.org/W2915910399","https://openalex.org/W2923685508","https://openalex.org/W2935451440","https://openalex.org/W2969650960","https://openalex.org/W2973770593","https://openalex.org/W2976773901","https://openalex.org/W2988527721","https://openalex.org/W2988865641","https://openalex.org/W2995345152","https://openalex.org/W3007441168","https://openalex.org/W3015946618","https://openalex.org/W3030472025","https://openalex.org/W3033043146","https://openalex.org/W3033555330","https://openalex.org/W3036152249","https://openalex.org/W3037513648","https://openalex.org/W3042410501","https://openalex.org/W3044132284","https://openalex.org/W3080385265","https://openalex.org/W3083952170","https://openalex.org/W3087521855","https://openalex.org/W3088080395","https://openalex.org/W3089948855","https://openalex.org/W3099272715","https://openalex.org/W3119065949","https://openalex.org/W3126082788","https://openalex.org/W3129013255","https://openalex.org/W3137955864","https://openalex.org/W3202652253","https://openalex.org/W3205516445","https://openalex.org/W3207242288","https://openalex.org/W3215555618","https://openalex.org/W4210278962","https://openalex.org/W4212785156","https://openalex.org/W4214581632","https://openalex.org/W4220705422","https://openalex.org/W4249622825","https://openalex.org/W4281662778","https://openalex.org/W4281749196","https://openalex.org/W4284711288","https://openalex.org/W4287091850","https://openalex.org/W4293769747","https://openalex.org/W4308429213","https://openalex.org/W4390461873","https://openalex.org/W6715961627","https://openalex.org/W6758840549"],"related_works":["https://openalex.org/W3185980711","https://openalex.org/W4401433847","https://openalex.org/W4410572336","https://openalex.org/W4307558402","https://openalex.org/W6962815701","https://openalex.org/W149864478","https://openalex.org/W4409894709","https://openalex.org/W2119682748","https://openalex.org/W7099095672","https://openalex.org/W7202286598"],"abstract_inverted_index":{"Osteoporosis":[0],"(OP)":[1],"is":[2,12,23,46,91],"one":[3],"of":[4,29,35,87,127,160,172,178,185,195],"the":[5,16,47,85,158,170,181],"most":[6],"common":[7],"metabolic":[8],"skeletal":[9],"disorders":[10],"and":[11,19,38,53,65,99,105,124,131,143,154,174,183,187,193],"commonly":[13],"seen":[14],"in":[15,117,129,180],"elderly":[17],"population":[18],"postmenopausal":[20],"women.":[21],"It":[22],"mainly":[24],"associated":[25],"with":[26,96],"progressive":[27],"loss":[28],"bone":[30,36,115],"mineral":[31],"density,":[32],"persistent":[33],"deterioration":[34],"microarchitecture,":[37],"increased":[39],"fracture":[40],"risk.":[41],"To":[42],"date,":[43],"drug":[44,58,63],"therapy":[45,59],"primary":[48],"method":[49],"used":[50,150],"to":[51,62,140],"prevent":[52],"treat":[54],"osteoporosis.":[55,133],"However,":[56],"long-term":[57],"inevitably":[60],"leads":[61],"resistance":[64],"specific":[66],"side":[67],"effects.":[68],"Therefore,":[69],"researchers":[70],"are":[71],"constantly":[72],"searching":[73],"for":[74,84,113,157,190],"new":[75],"monomer":[76],"compounds":[77],"from":[78],"natural":[79,93],"plants.":[80],"As":[81],"a":[82,92,152],"candidate":[83],"treatment":[86,159],"osteoporosis,":[88],"curcumin":[89,128,147,179],"(CUR)":[90],"phenolic":[94],"compound":[95,108],"various":[97,118],"pharmacological":[98,142],"biological":[100],"activities,":[101],"including":[102],"antioxidant,":[103],"anti-apoptotic,":[104],"anti-inflammatory.":[106],"This":[107,167],"has":[109],"gained":[110],"research":[111,192],"attention":[112],"maintaining":[114],"health":[116],"osteoporosis":[119,161,186],"models.":[120],"We":[121],"reviewed":[122],"preclinical":[123],"clinical":[125,144],"studies":[126],"preventing":[130],"alleviating":[132],"These":[134],"results":[135],"suggest":[136],"that":[137],"if":[138],"subjected":[139],"rigorous":[141],"trials,":[145],"naturally-derived":[146],"could":[148],"be":[149],"as":[151],"complementary":[153],"alternative":[155],"medicine":[156],"by":[162],"targeting":[163],"osteoporosis-related":[164],"mechanistic":[165],"pathways.":[166],"review":[168],"summarizes":[169],"mechanisms":[171],"action":[173],"potential":[175],"therapeutic":[176],"applications":[177],"prevention":[182],"mitigation":[184],"provides":[188],"reference":[189],"further":[191],"development":[194],"curcumin.":[196]},"counts_by_year":[{"year":2026,"cited_by_count":21},{"year":2025,"cited_by_count":19},{"year":2024,"cited_by_count":12}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-09-20T00:00:00"}