{"id":"https://openalex.org/W4386849657","doi":"https://doi.org/10.3390/jpm13091395","title":"Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder","display_name":"Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder","publication_year":2023,"publication_date":"2023-09-18","ids":{"openalex":"https://openalex.org/W4386849657","doi":"https://doi.org/10.3390/jpm13091395","pmid":"https://pubmed.ncbi.nlm.nih.gov/37763162","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10533016"},"language":"en","primary_location":{"id":"doi:10.3390/jpm13091395","doi":"https://doi.org/10.3390/jpm13091395","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jpm13091395","pdf_url":"https://www.mdpi.com/2075-4426/13/9/1395/pdf?version=1695203155","source":{"id":"https://openalex.org/S2736780684","display_name":"Journal of Personalized Medicine","issn_l":"2075-4426","issn":["2075-4426"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","erih-plus","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Personalized Medicine","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2075-4426/13/9/1395/pdf?version=1695203155","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5092899797","display_name":"Anton Shkundin","orcid":"https://orcid.org/0009-0002-3241-2619","observed_orcids":["https://orcid.org/0009-0002-3241-2619"]},"institutions":[{"id":"https://openalex.org/I1304196042","display_name":"Loyola University Medical Center","ror":"https://ror.org/05xcyt367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1304196042","https://openalex.org/I1304269903"]},{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]},{"id":"https://openalex.org/I4210159390","display_name":"Loyola Medicine","ror":"https://ror.org/04azs9g49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210159390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anton Shkundin","raw_affiliation_strings":["Department of Psychiatry and Behavioral Neurosciences, Loyola University Chicago Stritch School of Medicine, Loyola University Medical Center, Maywood, IL 60153, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Behavioral Neurosciences, Loyola University Chicago Stritch School of Medicine, Loyola University Medical Center, Maywood, IL 60153, USA","institution_ids":["https://openalex.org/I1304196042","https://openalex.org/I1925986","https://openalex.org/I4210159390"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015828524","display_name":"Angelos E Halaris","orcid":"https://orcid.org/0000-0002-6709-3067","observed_orcids":["https://orcid.org/0000-0002-6709-3067"]},"institutions":[{"id":"https://openalex.org/I1304196042","display_name":"Loyola University Medical Center","ror":"https://ror.org/05xcyt367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1304196042","https://openalex.org/I1304269903"]},{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]},{"id":"https://openalex.org/I4210159390","display_name":"Loyola Medicine","ror":"https://ror.org/04azs9g49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210159390"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Angelos Halaris","raw_affiliation_strings":["Department of Psychiatry and Behavioral Neurosciences, Loyola University Chicago Stritch School of Medicine, Loyola University Medical Center, Maywood, IL 60153, USA"],"raw_orcid":"https://orcid.org/0000-0002-6709-3067","affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Behavioral Neurosciences, Loyola University Chicago Stritch School of Medicine, Loyola University Medical Center, Maywood, IL 60153, USA","institution_ids":["https://openalex.org/I1304196042","https://openalex.org/I1925986","https://openalex.org/I4210159390"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015828524"],"corresponding_institution_ids":["https://openalex.org/I1304196042","https://openalex.org/I1925986","https://openalex.org/I4210159390"],"apc_list":{"value":2000,"currency":"CHF","value_usd":2224},"apc_paid":{"value":2000,"currency":"CHF","value_usd":2224},"fwci":2.5451,"has_fulltext":true,"cited_by_count":59,"citation_normalized_percentile":{"value":0.92217595,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"13","issue":"9","first_page":"1395","last_page":"1395"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.3921000063419342,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.3921000063419342,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.3379000127315521,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.07599999755620956,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brain-derived-neurotrophic-factor","display_name":"brain-derived neurotrophic factor","score":0.9200000166893005},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9240000247955322},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.8169999718666077},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":1.0},{"id":"https://openalex.org/keywords/bipolar-disorder","display_name":"bipolar disorder","score":1.0},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.6809999942779541},{"id":"https://openalex.org/keywords/linkage-disequilibrium","display_name":"linkage disequilibrium","score":0.925000011920929},{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.8849999904632568},{"id":"https://openalex.org/keywords/early-life-experience","display_name":"early life experience","score":0.8289999961853027},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.8040000200271606},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.8159999847412109}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6395566463470459},{"id":"https://openalex.org/C160539049","wikidata":"https://www.wikidata.org/wiki/Q3064187","display_name":"Neurotrophic factors","level":3,"score":0.6173315048217773},{"id":"https://openalex.org/C2778790584","wikidata":"https://www.wikidata.org/wiki/Q123045","display_name":"Brain-derived neurotrophic factor","level":4,"score":0.5794989466667175},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5263111591339111},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.500037431716919},{"id":"https://openalex.org/C37000724","wikidata":"https://www.wikidata.org/wiki/Q50430226","display_name":"Serotonergic","level":4,"score":0.43855130672454834},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.42052149772644043},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3282639980316162},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32682910561561584},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3070562183856964},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17914149165153503},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15930843353271484},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10621359944343567},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.09108719229698181},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/jpm13091395","doi":"https://doi.org/10.3390/jpm13091395","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jpm13091395","pdf_url":"https://www.mdpi.com/2075-4426/13/9/1395/pdf?version=1695203155","source":{"id":"https://openalex.org/S2736780684","display_name":"Journal of Personalized Medicine","issn_l":"2075-4426","issn":["2075-4426"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","erih-plus","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Personalized Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10533016","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10533016","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10533016/pdf/jpm-13-01395.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Pers Med","raw_type":"Text"},{"id":"pmid:37763162","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37763162","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of personalized medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/jpm13091395","doi":"https://doi.org/10.3390/jpm13091395","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jpm13091395","pdf_url":"https://www.mdpi.com/2075-4426/13/9/1395/pdf?version=1695203155","source":{"id":"https://openalex.org/S2736780684","display_name":"Journal of Personalized Medicine","issn_l":"2075-4426","issn":["2075-4426"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","erih-plus","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Personalized Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386849657.pdf","grobid_xml":"https://content.openalex.org/works/W4386849657.grobid-xml"},"referenced_works_count":186,"referenced_works":["https://openalex.org/W40040914","https://openalex.org/W109437506","https://openalex.org/W247880967","https://openalex.org/W1256176685","https://openalex.org/W1481286756","https://openalex.org/W1553642515","https://openalex.org/W1877874306","https://openalex.org/W1948888820","https://openalex.org/W1954468852","https://openalex.org/W1966053119","https://openalex.org/W1969713762","https://openalex.org/W1971964170","https://openalex.org/W1973114890","https://openalex.org/W1980785247","https://openalex.org/W1986026734","https://openalex.org/W1989260348","https://openalex.org/W1990942652","https://openalex.org/W1995216412","https://openalex.org/W1996371590","https://openalex.org/W1997408008","https://openalex.org/W1997671128","https://openalex.org/W2001058703","https://openalex.org/W2003982930","https://openalex.org/W2008459275","https://openalex.org/W2008867668","https://openalex.org/W2010722062","https://openalex.org/W2014007437","https://openalex.org/W2014911628","https://openalex.org/W2017320329","https://openalex.org/W2019789178","https://openalex.org/W2033173751","https://openalex.org/W2036543911","https://openalex.org/W2037820216","https://openalex.org/W2038184258","https://openalex.org/W2039680040","https://openalex.org/W2040649786","https://openalex.org/W2047262956","https://openalex.org/W2049199627","https://openalex.org/W2054314829","https://openalex.org/W2064701697","https://openalex.org/W2067302534","https://openalex.org/W2068080380","https://openalex.org/W2072509602","https://openalex.org/W2075117930","https://openalex.org/W2077059435","https://openalex.org/W2079338662","https://openalex.org/W2079965790","https://openalex.org/W2082520242","https://openalex.org/W2082708712","https://openalex.org/W2084899195","https://openalex.org/W2086755370","https://openalex.org/W2091340545","https://openalex.org/W2092241100","https://openalex.org/W2097704872","https://openalex.org/W2099896700","https://openalex.org/W2102268845","https://openalex.org/W2109163956","https://openalex.org/W2110696099","https://openalex.org/W2114908592","https://openalex.org/W2121864902","https://openalex.org/W2126505876","https://openalex.org/W2146337941","https://openalex.org/W2148443235","https://openalex.org/W2150379986","https://openalex.org/W2153307757","https://openalex.org/W2154942988","https://openalex.org/W2154979488","https://openalex.org/W2157696194","https://openalex.org/W2160187938","https://openalex.org/W2175885063","https://openalex.org/W2184290988","https://openalex.org/W2186244073","https://openalex.org/W2201002490","https://openalex.org/W2247777733","https://openalex.org/W2252543779","https://openalex.org/W2266543467","https://openalex.org/W2295850979","https://openalex.org/W2313958813","https://openalex.org/W2319566854","https://openalex.org/W2319979901","https://openalex.org/W2332043623","https://openalex.org/W2344757299","https://openalex.org/W2397958233","https://openalex.org/W2398540073","https://openalex.org/W2403520022","https://openalex.org/W2418018638","https://openalex.org/W2479603902","https://openalex.org/W2481216324","https://openalex.org/W2508014140","https://openalex.org/W2510652590","https://openalex.org/W2529367799","https://openalex.org/W2529641263","https://openalex.org/W2550099708","https://openalex.org/W2557402627","https://openalex.org/W2595534083","https://openalex.org/W2596929889","https://openalex.org/W2599052490","https://openalex.org/W2624853583","https://openalex.org/W2724252970","https://openalex.org/W2727301451","https://openalex.org/W2739135959","https://openalex.org/W2742879010","https://openalex.org/W2759724751","https://openalex.org/W2760283671","https://openalex.org/W2765509638","https://openalex.org/W2779686304","https://openalex.org/W2782593501","https://openalex.org/W2795176598","https://openalex.org/W2800406500","https://openalex.org/W2800660639","https://openalex.org/W2808542383","https://openalex.org/W2836017156","https://openalex.org/W2884768293","https://openalex.org/W2886207958","https://openalex.org/W2890779713","https://openalex.org/W2891212491","https://openalex.org/W2898400481","https://openalex.org/W2903442412","https://openalex.org/W2911508257","https://openalex.org/W2915044328","https://openalex.org/W2933196072","https://openalex.org/W2933289315","https://openalex.org/W2959131866","https://openalex.org/W2963936193","https://openalex.org/W2969640270","https://openalex.org/W2977701051","https://openalex.org/W2999809486","https://openalex.org/W3004917433","https://openalex.org/W3006523294","https://openalex.org/W3011369814","https://openalex.org/W3017057556","https://openalex.org/W3033844978","https://openalex.org/W3048783488","https://openalex.org/W3087508426","https://openalex.org/W3087811357","https://openalex.org/W3089704666","https://openalex.org/W3093209555","https://openalex.org/W3094053673","https://openalex.org/W3106205546","https://openalex.org/W3107358393","https://openalex.org/W3113167854","https://openalex.org/W3129572106","https://openalex.org/W3129604066","https://openalex.org/W3132152294","https://openalex.org/W3161211583","https://openalex.org/W3168318939","https://openalex.org/W3178902999","https://openalex.org/W3183171513","https://openalex.org/W3200333446","https://openalex.org/W3203420923","https://openalex.org/W3209369842","https://openalex.org/W3212023300","https://openalex.org/W4200029705","https://openalex.org/W4200050093","https://openalex.org/W4206500632","https://openalex.org/W4220852789","https://openalex.org/W4220956599","https://openalex.org/W4221094356","https://openalex.org/W4224242302","https://openalex.org/W4280581221","https://openalex.org/W4284712246","https://openalex.org/W4284989236","https://openalex.org/W4285495911","https://openalex.org/W4285742001","https://openalex.org/W4291010759","https://openalex.org/W4296100451","https://openalex.org/W4312128936","https://openalex.org/W4317426608","https://openalex.org/W4317512931","https://openalex.org/W4319869357","https://openalex.org/W4321488216","https://openalex.org/W4327791327","https://openalex.org/W4361214588","https://openalex.org/W4362663913","https://openalex.org/W4366292571","https://openalex.org/W4376630875","https://openalex.org/W4377086569","https://openalex.org/W4377695193","https://openalex.org/W4381661206","https://openalex.org/W4381996182","https://openalex.org/W4382931719","https://openalex.org/W6628733265","https://openalex.org/W6649743379","https://openalex.org/W6674935128","https://openalex.org/W6742695844","https://openalex.org/W6752831813"],"related_works":["https://openalex.org/W2033173751","https://openalex.org/W1580174237","https://openalex.org/W2068850049","https://openalex.org/W4416854851","https://openalex.org/W1986956972","https://openalex.org/W2035172439","https://openalex.org/W2086280178","https://openalex.org/W7036041319","https://openalex.org/W2093154571","https://openalex.org/W2185178219"],"abstract_inverted_index":{"Brain-Derived":[0],"Neurotrophic":[1],"Factor":[2],"(BDNF)":[3],"is":[4,27,73],"crucial":[5],"for":[6],"various":[7],"aspects":[8],"of":[9,34,80,103,130,174,191],"neuronal":[10,21],"development":[11],"and":[12,19,24,32,38,49,54,63,78,85,90,124,142,151,162,187],"function,":[13,163],"including":[14,148],"synaptic":[15,47],"plasticity,":[16],"neurotransmitter":[17],"release,":[18],"supporting":[20],"differentiation,":[22],"growth,":[23],"survival.":[25],"It":[26],"involved":[28],"in":[29,61,108,159],"the":[30,46,76,101,138,189],"formation":[31],"preservation":[33],"dopaminergic,":[35],"serotonergic,":[36],"GABAergic,":[37],"cholinergic":[39],"neurons,":[40],"facilitating":[41,82],"efficient":[42],"stimulus":[43],"transmission":[44],"within":[45,111],"system":[48],"contributing":[50,86],"to":[51,75,87,98,157,166,194],"learning,":[52],"memory,":[53],"overall":[55],"cognition.":[56],"Furthermore,":[57],"BDNF":[58,69],"demonstrates":[59],"involvement":[60],"neuroinflammation":[62],"showcases":[64],"neuroprotective":[65],"effects.":[66],"In":[67],"contrast,":[68],"antisense":[70],"RNA":[71],"(BDNF-AS)":[72],"linked":[74],"regulation":[77],"control":[79],"BDNF,":[81],"its":[83],"suppression":[84],"neurotoxicity,":[88],"apoptosis,":[89],"decreased":[91],"cell":[92],"viability.":[93],"This":[94],"review":[95],"article":[96],"aims":[97],"comprehensively":[99],"overview":[100],"significance":[102],"single":[104],"nucleotide":[105],"polymorphisms":[106],"(SNPs)":[107],"BDNF/BDNF-AS":[109,132,175],"genes":[110],"psychiatric":[112],"conditions,":[113],"with":[114,121,153],"a":[115],"specific":[116],"focus":[117],"on":[118],"their":[119,143],"associations":[120],"depression,":[122],"schizophrenia,":[123],"bipolar":[125],"disorder.":[126],"The":[127,170],"independent":[128],"influence":[129],"each":[131],"gene":[133],"variation,":[134],"as":[135,137],"well":[136],"interplay":[139],"between":[140],"SNPs":[141],"linkage":[144],"disequilibrium,":[145],"environmental":[146],"factors,":[147],"early-life":[149],"experiences,":[150],"interactions":[152],"other":[154],"genes,":[155],"lead":[156],"alterations":[158],"brain":[160],"architecture":[161],"shaping":[164],"vulnerability":[165],"mental":[167],"health":[168],"disorders.":[169],"potential":[171],"translational":[172],"applications":[173],"polymorphism":[176],"knowledge":[177],"can":[178],"revolutionize":[179],"personalized":[180],"medicine,":[181],"predict":[182],"disease":[183],"susceptibility,":[184],"treatment":[185],"outcomes,":[186],"guide":[188],"selection":[190],"interventions":[192],"tailored":[193],"individual":[195],"patients.":[196]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":23},{"year":2024,"cited_by_count":21}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-09-20T00:00:00"}
