{"id":"https://openalex.org/W4386827201","doi":"https://doi.org/10.1016/j.scr.2023.103207","title":"Generation of two induced pluripotent stem cell lines from Duchenne muscular dystrophy patients","display_name":"Generation of two induced pluripotent stem cell lines from Duchenne muscular dystrophy patients","publication_year":2023,"publication_date":"2023-09-18","ids":{"openalex":"https://openalex.org/W4386827201","doi":"https://doi.org/10.1016/j.scr.2023.103207","pmid":"https://pubmed.ncbi.nlm.nih.gov/37740996","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10949967"},"language":"en","primary_location":{"id":"doi:10.1016/j.scr.2023.103207","doi":"https://doi.org/10.1016/j.scr.2023.103207","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.scr.2023.103207","pdf_url":null,"source":{"id":"https://openalex.org/S81007815","display_name":"Stem Cell Research","issn_l":"1873-5061","issn":["1873-5061","1876-7753"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.scr.2023.103207","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100634309","display_name":"Wenqiang Liu","orcid":"https://orcid.org/0000-0002-2323-7962","observed_orcids":["https://orcid.org/0000-0002-2323-7962"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4405269264","display_name":"Stanford Cardiovascular Institute","ror":"https://ror.org/03kk52s14","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wenqiang Liu","raw_affiliation_strings":["Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100907012","display_name":"Wenshu Zeng","orcid":"https://orcid.org/0000-0003-4029-2397","observed_orcids":["https://orcid.org/0000-0003-4029-2397"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4405269264","display_name":"Stanford Cardiovascular Institute","ror":"https://ror.org/03kk52s14","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wenshu Zeng","raw_affiliation_strings":["Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101835366","display_name":"Xiaohui Kong","orcid":"https://orcid.org/0000-0002-8353-3288","observed_orcids":["https://orcid.org/0000-0002-8353-3288"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4405269264","display_name":"Stanford Cardiovascular Institute","ror":"https://ror.org/03kk52s14","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaohui Kong","raw_affiliation_strings":["Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092894454","display_name":"Min Htet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4405269264","display_name":"Stanford Cardiovascular Institute","ror":"https://ror.org/03kk52s14","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Min Htet","raw_affiliation_strings":["Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111263431","display_name":"Rebecca Yu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rebecca Yu","raw_affiliation_strings":["Greenstone Biosciences, Palo Alto, CA 94304, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greenstone Biosciences, Palo Alto, CA 94304, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053510600","display_name":"Matthew Thomas Wheeler","orcid":"https://orcid.org/0000-0001-8721-3022","observed_orcids":["https://orcid.org/0000-0001-8721-3022"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4405269264","display_name":"Stanford Cardiovascular Institute","ror":"https://ror.org/03kk52s14","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew Wheeler","raw_affiliation_strings":["Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042201706","display_name":"John Day","orcid":"https://orcid.org/0000-0002-0086-9529","observed_orcids":["https://orcid.org/0000-0002-0086-9529"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John W. Day","raw_affiliation_strings":["Department of Neurology, Stanford University, Stanford, CA 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Stanford University, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047561254","display_name":"Joseph C. Wu","orcid":"https://orcid.org/0000-0002-6068-8041","observed_orcids":["https://orcid.org/0000-0002-6068-8041","https://orcid.org/0000-0003-4274-0413"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I4405269264","display_name":"Stanford Cardiovascular Institute","ror":"https://ror.org/03kk52s14","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joseph C. Wu","raw_affiliation_strings":["Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: joewu@stanford.edu","Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA"],"raw_orcid":"https://orcid.org/0000-0002-6068-8041","affiliations":[{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: joewu@stanford.edu","institution_ids":["https://openalex.org/I4405269264","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5047561254"],"corresponding_institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I4405269264","https://openalex.org/I97018004"],"apc_list":{"value":2210,"currency":"USD","value_usd":2210},"apc_paid":{"value":2210,"currency":"USD","value_usd":2210},"fwci":0.4753,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.53245286,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"72","issue":null,"first_page":"103207","last_page":"103207"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12400","display_name":"Neurogenetic and Muscular Disorders Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/duchenne-muscular-dystrophy","display_name":"Duchenne muscular dystrophy","score":1.0},{"id":"https://openalex.org/keywords/induced-pluripotent-stem-cells","display_name":"induced pluripotent stem cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dystrophin","display_name":"dystrophin","score":0.8880000114440918},{"id":"https://openalex.org/keywords/nonsense-mutation","display_name":"nonsense mutation","score":0.9850000143051147},{"id":"https://openalex.org/keywords/ipsc-differentiation","display_name":"iPSC differentiation","score":0.6769999861717224},{"id":"https://openalex.org/keywords/stem-cell-markers","display_name":"stem cell markers","score":0.8700000047683716},{"id":"https://openalex.org/keywords/disease-modeling","display_name":"disease modeling","score":0.6840000152587891},{"id":"https://openalex.org/keywords/treatment-development","display_name":"treatment development","score":0.6899999976158142}],"concepts":[{"id":"https://openalex.org/C107459253","wikidata":"https://www.wikidata.org/wiki/Q674925","display_name":"Induced pluripotent stem cell","level":4,"score":0.893630862236023},{"id":"https://openalex.org/C18155467","wikidata":"https://www.wikidata.org/wiki/Q660498","display_name":"Germ layer","level":5,"score":0.858117938041687},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8476411700248718},{"id":"https://openalex.org/C2778943923","wikidata":"https://www.wikidata.org/wiki/Q1648484","display_name":"Duchenne muscular dystrophy","level":2,"score":0.8036595582962036},{"id":"https://openalex.org/C2780394045","wikidata":"https://www.wikidata.org/wiki/Q412285","display_name":"Dystrophin","level":3,"score":0.6206456422805786},{"id":"https://openalex.org/C96777560","wikidata":"https://www.wikidata.org/wiki/Q518638","display_name":"Nonsense mutation","level":5,"score":0.5910493731498718},{"id":"https://openalex.org/C2779030066","wikidata":"https://www.wikidata.org/wiki/Q1137767","display_name":"Muscular dystrophy","level":2,"score":0.5609298944473267},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.48152193427085876},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.46602723002433777},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.42603030800819397},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.40744438767433167},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40211260318756104},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3629434108734131},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.34534865617752075},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13708725571632385},{"id":"https://openalex.org/C75563809","wikidata":"https://www.wikidata.org/wiki/Q2656896","display_name":"Missense mutation","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016189","descriptor_name":"Dystrophin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016189","descriptor_name":"Dystrophin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020388","descriptor_name":"Muscular Dystrophy, Duchenne","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D057026","descriptor_name":"Induced Pluripotent Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.scr.2023.103207","doi":"https://doi.org/10.1016/j.scr.2023.103207","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.scr.2023.103207","pdf_url":null,"source":{"id":"https://openalex.org/S81007815","display_name":"Stem Cell Research","issn_l":"1873-5061","issn":["1873-5061","1876-7753"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Research","raw_type":"journal-article"},{"id":"pmid:37740996","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37740996","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem cell research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10949967","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10949967","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10949967/pdf/nihms-1942272.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Stem Cell Res","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:aa3f872aa7874a50ba5ab5ab8227e0f0","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/aa3f872aa7874a50ba5ab5ab8227e0f0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Stem Cell Research, Vol 72, Iss , Pp 103207- (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.scr.2023.103207","doi":"https://doi.org/10.1016/j.scr.2023.103207","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.scr.2023.103207","pdf_url":null,"source":{"id":"https://openalex.org/S81007815","display_name":"Stem Cell Research","issn_l":"1873-5061","issn":["1873-5061","1876-7753"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2168952822","display_name":null,"funder_award_id":"75N92020D00019","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3897007235","display_name":null,"funder_award_id":"U01 FD005978","funder_id":"https://openalex.org/F4320332163","funder_display_name":"U.S. Food and Drug Administration"},{"id":"https://openalex.org/G5170875372","display_name":null,"funder_award_id":"75N92020D00019","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6926568331","display_name":null,"funder_award_id":"U01FD005978 #62","funder_id":"https://openalex.org/F4320332163","funder_display_name":"U.S. Food and Drug Administration"},{"id":"https://openalex.org/G9000877010","display_name":"Human iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated Cardiomyopathy","funder_award_id":"R01HL141371","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000884318","display_name":"Single-cell Multi-omic Profiling of Drug Responses Using Pooled iPSC-CM Differentiation","funder_award_id":"R01HL145676","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000901225","display_name":"Elucidating ECM Signaling in Cardiac Organoids with Machine Learning and Single-cell Multiomics","funder_award_id":"R01HL163680","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000910739","display_name":"Elucidating Anthracycline-Induced Cell Type-Specific Cardiovascular Toxicity with CRISPRi/a Screens","funder_award_id":"R01HL150693","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332163","display_name":"U.S. Food and Drug Administration","ror":"https://ror.org/034xvzb47"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386827201.pdf","grobid_xml":"https://content.openalex.org/works/W4386827201.grobid-xml"},"referenced_works_count":5,"referenced_works":["https://openalex.org/W2094835866","https://openalex.org/W2948019101","https://openalex.org/W3127238805","https://openalex.org/W3131782536","https://openalex.org/W4366124607"],"related_works":["https://openalex.org/W3047112678","https://openalex.org/W4297216104","https://openalex.org/W3106950733","https://openalex.org/W3202096985","https://openalex.org/W7202228413","https://openalex.org/W2795400625","https://openalex.org/W4213446589","https://openalex.org/W4412891702","https://openalex.org/W7160102214","https://openalex.org/W3090756040"],"abstract_inverted_index":{"Duchenne":[0],"muscular":[1],"dystrophy":[2],"(DMD)":[3],"is":[4],"an":[5],"X-linked":[6],"recessive":[7],"disorder":[8],"that":[9],"leads":[10],"to":[11,23,90],"death":[12],"in":[13,93],"early":[14],"adulthood.":[15],"Patients":[16],"with":[17,41,49],"DMD":[18,33,92],"have":[19],"null":[20],"mutations":[21],"leading":[22],"loss":[24],"of":[25,43,63,69,73],"functional":[26],"dystrophin":[27],"protein.":[28],"Here":[29],"we":[30],"generated":[31],"two":[32],"induced":[34],"pluripotent":[35],"stem":[36],"cell":[37],"(iPSC)":[38],"lines,":[39],"one":[40],"deletion":[42],"exon":[44],"51":[45],"and":[46,78,95],"the":[47,67,74],"other":[48],"a":[50,97],"single":[51],"nucleotide":[52],"nonsense":[53],"mutation":[54],"(c.10171C":[55],">":[56],"T).":[57],"Both":[58],"lines":[59,84],"expressed":[60],"high":[61],"levels":[62],"pluripotency":[64],"markers,":[65],"had":[66],"capability":[68],"differentiating":[70],"into":[71],"derivatives":[72],"three":[75],"germ":[76],"layers,":[77],"possessed":[79],"normal":[80],"karyotypes.":[81],"These":[82],"iPSC":[83],"can":[85],"serve":[86],"as":[87,96],"powerful":[88],"tools":[89],"model":[91],"vitro":[94],"platform":[98],"for":[99],"therapeutic":[100],"development.":[101]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2024,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2023-09-19T00:00:00"}