{"id":"https://openalex.org/W4386815654","doi":"https://doi.org/10.1016/j.lwt.2023.115315","title":"Exposure of hydrophobic groups affected the thermal aggregation of myosin based on experimental and molecular dynamics simulation","display_name":"Exposure of hydrophobic groups affected the thermal aggregation of myosin based on experimental and molecular dynamics simulation","publication_year":2023,"publication_date":"2023-09-01","ids":{"openalex":"https://openalex.org/W4386815654","doi":"https://doi.org/10.1016/j.lwt.2023.115315"},"language":"en","primary_location":{"id":"doi:10.1016/j.lwt.2023.115315","doi":"https://doi.org/10.1016/j.lwt.2023.115315","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.lwt.2023.115315","pdf_url":null,"source":{"id":"https://openalex.org/S26760650","display_name":"LWT","issn_l":"0023-6438","issn":["0023-6438","1096-1127"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"LWT","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.lwt.2023.115315","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044011881","display_name":"Xiangru Wei","orcid":"https://orcid.org/0000-0001-9711-9347","observed_orcids":["https://orcid.org/0000-0001-9711-9347"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]},{"id":"https://openalex.org/I4210099012","display_name":"Institute of Food Science and Technology","ror":"https://ror.org/01s5dew76","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210099012","https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210151987","display_name":"Ministry of Agriculture and Rural Affairs","ror":"https://ror.org/05ckt8b96","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987"]}],"countries":["CN","IE"],"is_corresponding":false,"raw_author_name":"Xiangru Wei","raw_affiliation_strings":["Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Beijing, 100193, PR China","University College Dublin, School of Agriculture and Food Science, Dublin 4, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Beijing, 100193, PR China","institution_ids":["https://openalex.org/I4210099012","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"raw_affiliation_string":"University College Dublin, School of Agriculture and Food Science, Dublin 4, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045418448","display_name":"Frank J. Monahan","orcid":"https://orcid.org/0000-0002-0938-6435","observed_orcids":["https://orcid.org/0000-0002-0938-6435"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Frank Monahan","raw_affiliation_strings":["University College Dublin, School of Agriculture and Food Science, Dublin 4, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University College Dublin, School of Agriculture and Food Science, Dublin 4, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113067313","display_name":"Chunjiang Zhang","orcid":"https://orcid.org/0000-0001-8592-5739","observed_orcids":["https://orcid.org/0000-0001-8592-5739"]},"institutions":[{"id":"https://openalex.org/I4210099012","display_name":"Institute of Food Science and Technology","ror":"https://ror.org/01s5dew76","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210099012","https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210151987","display_name":"Ministry of Agriculture and Rural Affairs","ror":"https://ror.org/05ckt8b96","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunjiang Zhang","raw_affiliation_strings":["Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Beijing, 100193, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Beijing, 100193, PR China","institution_ids":["https://openalex.org/I4210099012","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100344995","display_name":"Zhenyu Wang","orcid":"https://orcid.org/0000-0003-4478-1710","observed_orcids":["https://orcid.org/0000-0003-4478-1710"]},"institutions":[{"id":"https://openalex.org/I4210099012","display_name":"Institute of Food Science and Technology","ror":"https://ror.org/01s5dew76","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210099012","https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210151987","display_name":"Ministry of Agriculture and Rural Affairs","ror":"https://ror.org/05ckt8b96","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhenyu Wang","raw_affiliation_strings":["Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Beijing, 100193, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Beijing, 100193, PR China","institution_ids":["https://openalex.org/I4210099012","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100721675","display_name":"Dequan Zhang","orcid":"https://orcid.org/0000-0003-3277-6113","observed_orcids":["https://orcid.org/0000-0003-3277-6113"]},"institutions":[{"id":"https://openalex.org/I4210099012","display_name":"Institute of Food Science and Technology","ror":"https://ror.org/01s5dew76","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210099012","https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210151987","display_name":"Ministry of Agriculture and Rural Affairs","ror":"https://ror.org/05ckt8b96","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dequan Zhang","raw_affiliation_strings":["Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Beijing, 100193, PR China"],"raw_orcid":"https://orcid.org/0000-0003-3277-6113","affiliations":[{"raw_affiliation_string":"Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Beijing, 100193, PR China","institution_ids":["https://openalex.org/I4210099012","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100344995","https://openalex.org/A5100721675"],"corresponding_institution_ids":["https://openalex.org/I4210099012","https://openalex.org/I4210138501","https://openalex.org/I4210151987"],"apc_list":{"value":2250,"currency":"USD","value_usd":2250},"apc_paid":{"value":2250,"currency":"USD","value_usd":2250},"fwci":4.1616,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.94281178,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"187","issue":null,"first_page":"115315","last_page":"115315"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10333","display_name":"Meat and Animal Product Quality","score":0.7490000128746033,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10333","display_name":"Meat and Animal Product Quality","score":0.7490000128746033,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10411","display_name":"Proteins in Food Systems","score":0.2329999953508377,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.01209999993443489,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myosin","display_name":"myosin","score":0.9229999780654907},{"id":"https://openalex.org/keywords/thermal-aggregation","display_name":"thermal aggregation","score":0.7720000147819519},{"id":"https://openalex.org/keywords/hydrophobic-groups","display_name":"hydrophobic groups","score":0.7799999713897705},{"id":"https://openalex.org/keywords/protein-denaturation","display_name":"protein denaturation","score":0.7020000219345093},{"id":"https://openalex.org/keywords/disulfide-bonds","display_name":"disulfide bonds","score":0.7850000262260437},{"id":"https://openalex.org/keywords/hydrophobic-interactions","display_name":"hydrophobic interactions","score":0.8090000152587891},{"id":"https://openalex.org/keywords/protein-unfolding","display_name":"protein unfolding","score":0.7009999752044678},{"id":"https://openalex.org/keywords/electrostatic-energy","display_name":"electrostatic energy","score":0.6690000295639038},{"id":"https://openalex.org/keywords/ca2-atpase-activity","display_name":"Ca2+-ATPase activity","score":0.8029999732971191}],"concepts":[{"id":"https://openalex.org/C6997183","wikidata":"https://www.wikidata.org/wiki/Q271727","display_name":"Myosin","level":2,"score":0.8808184862136841},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6525552272796631},{"id":"https://openalex.org/C90260826","wikidata":"https://www.wikidata.org/wiki/Q899157","display_name":"Hydrophobic effect","level":2,"score":0.6174051761627197},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5850071310997009},{"id":"https://openalex.org/C59593255","wikidata":"https://www.wikidata.org/wiki/Q901663","display_name":"Molecular dynamics","level":2,"score":0.5836912393569946},{"id":"https://openalex.org/C133571119","wikidata":"https://www.wikidata.org/wiki/Q899102","display_name":"Circular dichroism","level":2,"score":0.5404585003852844},{"id":"https://openalex.org/C2778021804","wikidata":"https://www.wikidata.org/wiki/Q13359586","display_name":"Myosin ATPase","level":4,"score":0.47332391142845154},{"id":"https://openalex.org/C136238340","wikidata":"https://www.wikidata.org/wiki/Q7251455","display_name":"Protein aggregation","level":2,"score":0.4485873878002167},{"id":"https://openalex.org/C27256138","wikidata":"https://www.wikidata.org/wiki/Q1230226","display_name":"Disulfide bond","level":2,"score":0.41542333364486694},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3263041377067566},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.2618106007575989},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24268591403961182},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.16252845525741577},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.12909650802612305},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.lwt.2023.115315","doi":"https://doi.org/10.1016/j.lwt.2023.115315","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.lwt.2023.115315","pdf_url":null,"source":{"id":"https://openalex.org/S26760650","display_name":"LWT","issn_l":"0023-6438","issn":["0023-6438","1096-1127"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"LWT","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.lwt.2023.115315","doi":"https://doi.org/10.1016/j.lwt.2023.115315","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.lwt.2023.115315","pdf_url":null,"source":{"id":"https://openalex.org/S26760650","display_name":"LWT","issn_l":"0023-6438","issn":["0023-6438","1096-1127"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","norway-1","oarl","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"LWT","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4172408302","display_name":null,"funder_award_id":"CAAS-ASTIP-2018-IAPPST-2","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G7136692898","display_name":null,"funder_award_id":"2019YFC1606200","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1966072993","https://openalex.org/W1966405132","https://openalex.org/W1982584221","https://openalex.org/W1999656017","https://openalex.org/W2000665577","https://openalex.org/W2011067214","https://openalex.org/W2039501634","https://openalex.org/W2039924070","https://openalex.org/W2043805597","https://openalex.org/W2052104153","https://openalex.org/W2052824603","https://openalex.org/W2055236140","https://openalex.org/W2068399047","https://openalex.org/W2071056893","https://openalex.org/W2085994767","https://openalex.org/W2092279877","https://openalex.org/W2099747806","https://openalex.org/W2106889817","https://openalex.org/W2142522385","https://openalex.org/W2313458242","https://openalex.org/W2327456952","https://openalex.org/W2563733696","https://openalex.org/W2735978187","https://openalex.org/W2752973534","https://openalex.org/W2774753308","https://openalex.org/W2805983363","https://openalex.org/W2942690317","https://openalex.org/W2952046340","https://openalex.org/W2964255315","https://openalex.org/W2981786407","https://openalex.org/W3011218058","https://openalex.org/W3012862802","https://openalex.org/W3013865598","https://openalex.org/W3022044491","https://openalex.org/W3025013523","https://openalex.org/W3143848083","https://openalex.org/W3153619423","https://openalex.org/W3154509847","https://openalex.org/W3208325862","https://openalex.org/W4213422350","https://openalex.org/W4353050220"],"related_works":["https://openalex.org/W4389334914","https://openalex.org/W2942690317","https://openalex.org/W1966405132","https://openalex.org/W2050580718","https://openalex.org/W4413120965","https://openalex.org/W2885159606","https://openalex.org/W4416377184","https://openalex.org/W1997751514","https://openalex.org/W1863486023","https://openalex.org/W7167588838"],"abstract_inverted_index":{"In":[0],"this":[1],"study,":[2],"Beijing":[3],"duck":[4],"breast":[5],"myosin":[6,32,41,78,94,109],"was":[7,73],"used":[8],"to":[9,49,75,119],"analyze":[10],"the":[11,31,40,50,77,91,116,121,142],"structural":[12,57],"and":[13,22,43,65,83,101,115],"functional":[14],"changes":[15],"during":[16],"thermal":[17],"treatments.":[18],"The":[19,68,130],"particle":[20],"size":[21],"atomic":[23],"force":[24],"microscopy":[25],"(AFM)":[26],"imaging":[27],"results":[28],"showed":[29],"that":[30,105],"polymer":[33],"formed":[34],"generously":[35],"at":[36,45,80,96,127],"55":[37,81,113],"\u00b0C.":[38,98,129],"Meanwhile,":[39],"denatured":[42],"unfolded":[44],"50\u201355":[46],"\u00b0C":[47],"leading":[48],"exposure":[51],"of":[52,70,93,108,137,144],"hydrophobic":[53,71],"groups":[54],"detected":[55],"by":[56],"determinations":[58],"including":[59],"circular":[60],"dichroism":[61],"(CD),":[62],"sulfhydryl":[63],"content":[64],"Ca2+-ATPase":[66],"activity.":[67],"increase":[69],"interaction":[72],"observed":[74],"promote":[76,120],"aggregation":[79,122,143],"\u00b0C,":[82,114],"disulfide":[84],"bonds":[85],"played":[86],"a":[87,134],"supplementary":[88],"role":[89],"in":[90],"stabilization":[92],"aggregates":[95],"80":[97,128],"Molecular":[99],"docking":[100],"dynamics":[102],"simulation":[103],"verified":[104],"electrostatic":[106],"energy":[107,125],"decreased":[110],"on":[111],"reaching":[112],"hydrophobicity":[117],"increased":[118,126],"while":[123],"kinetic":[124],"presented":[131],"study":[132],"provided":[133],"potential":[135],"selection":[136],"processing":[138],"temperature":[139],"conditions":[140],"from":[141],"protein.":[145]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-09-18T00:00:00"}