{"id":"https://openalex.org/W4386780751","doi":"https://doi.org/10.4274/nkmj.galenos.2023.74436","title":"Effect of PDE 5 Inhibitor-Avanafil on Renal Ischemia/Reperfusion Injury in Rats","display_name":"Effect of PDE 5 Inhibitor-Avanafil on Renal Ischemia/Reperfusion Injury in Rats","publication_year":2023,"publication_date":"2023-09-15","ids":{"openalex":"https://openalex.org/W4386780751","doi":"https://doi.org/10.4274/nkmj.galenos.2023.74436"},"language":"en","primary_location":{"id":"doi:10.4274/nkmj.galenos.2023.74436","doi":"https://doi.org/10.4274/nkmj.galenos.2023.74436","is_oa":true,"landing_page_url":"https://doi.org/10.4274/nkmj.galenos.2023.74436","pdf_url":"https://doi.org/10.4274/nkmj.galenos.2023.74436","source":{"id":"https://openalex.org/S4210225446","display_name":"Nam\u0131k Kemal T\u0131p Dergisi","issn_l":"2587-0262","issn":["2587-0262"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nam\u0131k Kemal T\u0131p Dergisi","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4274/nkmj.galenos.2023.74436","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050520755","display_name":"Tu\u011fba Nurcan Y\u00fcksel","orcid":"https://orcid.org/0000-0001-5092-1674","observed_orcids":["https://orcid.org/0000-0001-5092-1674"]},"institutions":[{"id":"https://openalex.org/I125454184","display_name":"Tekirda\u011f Nam\u0131k Kemal University","ror":"https://ror.org/01a0mk874","country_code":"TR","type":"education","lineage":["https://openalex.org/I125454184"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Tu\u011fba Nurcan Y\u00dcKSEL","raw_affiliation_strings":["Tekirda\u011f Nam\u0131k Kemal University Faculty of Medicine , Department of Pharmacology , Tekirda\u011f , Turkey","University Faculty of Medicine, Department of Pharmacology, Tekirda\u011f, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-5092-1674","affiliations":[{"raw_affiliation_string":"Tekirda\u011f Nam\u0131k Kemal University Faculty of Medicine , Department of Pharmacology , Tekirda\u011f , Turkey","institution_ids":["https://openalex.org/I125454184"]},{"raw_affiliation_string":"University Faculty of Medicine, Department of Pharmacology, Tekirda\u011f, Turkey","institution_ids":["https://openalex.org/I125454184"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043261050","display_name":"Zekai Hal\u0131c\u0131","orcid":"https://orcid.org/0000-0001-6854-6059","observed_orcids":["https://orcid.org/0000-0001-6854-6059"]},"institutions":[{"id":"https://openalex.org/I64134780","display_name":"Atat\u00fcrk University","ror":"https://ror.org/03je5c526","country_code":"TR","type":"education","lineage":["https://openalex.org/I64134780"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Zekai HALICI","raw_affiliation_strings":["Atat\u00fcrk University Faculty of Medicine, Department of Pharmacology-Clinical Research, Development and Design Application and Research Center, Erzurum, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-6854-6059","affiliations":[{"raw_affiliation_string":"Atat\u00fcrk University Faculty of Medicine, Department of Pharmacology-Clinical Research, Development and Design Application and Research Center, Erzurum, Turkey","institution_ids":["https://openalex.org/I64134780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101510841","display_name":"C. Kaya","orcid":"https://orcid.org/0000-0001-9313-3686","observed_orcids":["https://orcid.org/0000-0001-9313-3686"]},"institutions":[{"id":"https://openalex.org/I4210146513","display_name":"\u0130stanbul Pendik Veteriner Kontrol Enstit\u00fcs\u00fc","ror":"https://ror.org/046h96256","country_code":"TR","type":"government","lineage":["https://openalex.org/I4210146513","https://openalex.org/I4405262973"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Cihangir KAYA","raw_affiliation_strings":["\u0130stanbul Pendik Veterinary Control Institute, Diagnostic Department, \u0130stanbul, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-9313-3686","affiliations":[{"raw_affiliation_string":"\u0130stanbul Pendik Veterinary Control Institute, Diagnostic Department, \u0130stanbul, Turkey","institution_ids":["https://openalex.org/I4210146513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057877927","display_name":"Ay\u015fe BOZKURT","orcid":"https://orcid.org/0000-0003-1551-949X","observed_orcids":["https://orcid.org/0000-0003-1551-949X"]},"institutions":[{"id":"https://openalex.org/I118567650","display_name":"Van Y\u00fcz\u00fcnc\u00fc Y\u0131l \u00dcniversitesi","ror":"https://ror.org/041jyzp61","country_code":"TR","type":"education","lineage":["https://openalex.org/I118567650"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ay\u015fe BOZKURT","raw_affiliation_strings":["Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Faculty of Medicine, Department of Pharmacology, Van, Turkey"],"raw_orcid":"https://orcid.org/0000-0003-1551-949X","affiliations":[{"raw_affiliation_string":"Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Faculty of Medicine, Department of Pharmacology, Van, Turkey","institution_ids":["https://openalex.org/I118567650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062864737","display_name":"Taha Tavac\u0131","orcid":"https://orcid.org/0000-0002-8284-8317","observed_orcids":["https://orcid.org/0000-0002-8284-8317"]},"institutions":[{"id":"https://openalex.org/I103703290","display_name":"Sakarya University","ror":"https://ror.org/04ttnw109","country_code":"TR","type":"education","lineage":["https://openalex.org/I103703290"]},{"id":"https://openalex.org/I135987583","display_name":"Kafkas University","ror":"https://ror.org/04v302n28","country_code":"TR","type":"education","lineage":["https://openalex.org/I135987583"]},{"id":"https://openalex.org/I64134780","display_name":"Atat\u00fcrk University","ror":"https://ror.org/03je5c526","country_code":"TR","type":"education","lineage":["https://openalex.org/I64134780"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Taha TAVACI","raw_affiliation_strings":["Sakarya University Faculty of Medicine, Department of Pharmacology, Sakarya, Turkey","Atat\u00fcrk University Faculty of Medicine, Department of Pharmacology, Erzurum, Turkey","Kafkas University Faculty of Medicine, Department of Histology and Embryology, Kars, Turkey"],"raw_orcid":"https://orcid.org/0000-0002-8284-8317","affiliations":[{"raw_affiliation_string":"Sakarya University Faculty of Medicine, Department of Pharmacology, Sakarya, Turkey","institution_ids":["https://openalex.org/I103703290"]},{"raw_affiliation_string":"Atat\u00fcrk University Faculty of Medicine, Department of Pharmacology, Erzurum, Turkey","institution_ids":["https://openalex.org/I64134780"]},{"raw_affiliation_string":"Kafkas University Faculty of Medicine, Department of Histology and Embryology, Kars, Turkey","institution_ids":["https://openalex.org/I135987583"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023902497","display_name":"Maide Sena Civelek","orcid":"https://orcid.org/0000-0001-8621-2765","observed_orcids":["https://orcid.org/0000-0001-8621-2765"]},"institutions":[{"id":"https://openalex.org/I125454184","display_name":"Tekirda\u011f Nam\u0131k Kemal University","ror":"https://ror.org/01a0mk874","country_code":"TR","type":"education","lineage":["https://openalex.org/I125454184"]},{"id":"https://openalex.org/I64134780","display_name":"Atat\u00fcrk University","ror":"https://ror.org/03je5c526","country_code":"TR","type":"education","lineage":["https://openalex.org/I64134780"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Maide Sena C\u0130VELEK","raw_affiliation_strings":["Atat\u00fcrk University Faculty of Medicine , Department of Pharmacology , Erzurum , Turkey","University Faculty of Medicine, Department of Pharmacology, Tekirda\u011f, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-8621-2765","affiliations":[{"raw_affiliation_string":"Atat\u00fcrk University Faculty of Medicine , Department of Pharmacology , Erzurum , Turkey","institution_ids":["https://openalex.org/I64134780"]},{"raw_affiliation_string":"University Faculty of Medicine, Department of Pharmacology, Tekirda\u011f, Turkey","institution_ids":["https://openalex.org/I125454184"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090335718","display_name":"Beng\u00fcl \u00d6zdemir","orcid":"https://orcid.org/0000-0003-2642-6096","observed_orcids":["https://orcid.org/0000-0003-2642-6096"]},"institutions":[{"id":"https://openalex.org/I125454184","display_name":"Tekirda\u011f Nam\u0131k Kemal University","ror":"https://ror.org/01a0mk874","country_code":"TR","type":"education","lineage":["https://openalex.org/I125454184"]},{"id":"https://openalex.org/I135987583","display_name":"Kafkas University","ror":"https://ror.org/04v302n28","country_code":"TR","type":"education","lineage":["https://openalex.org/I135987583"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Beng\u00fcl \u00d6ZDEM\u0130R","raw_affiliation_strings":["Kafkas University Faculty of Medicine , Department of Histology and Embryology , Kars , Turkey","University Faculty of Medicine, Department of Pharmacology, Tekirda\u011f, Turkey"],"raw_orcid":"https://orcid.org/0000-0003-2642-6096","affiliations":[{"raw_affiliation_string":"Kafkas University Faculty of Medicine , Department of Histology and Embryology , Kars , Turkey","institution_ids":["https://openalex.org/I135987583"]},{"raw_affiliation_string":"University Faculty of Medicine, Department of Pharmacology, Tekirda\u011f, Turkey","institution_ids":["https://openalex.org/I125454184"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3485,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.54864403,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"11","issue":"3","first_page":"284","last_page":"293"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13796","display_name":"Neuroprotection in Cerebral Ischemia","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/avanafil","display_name":"avanafil","score":0.9760000109672546},{"id":"https://openalex.org/keywords/phosphodiesterase-5-inhibitors","display_name":"phosphodiesterase-5 inhibitors","score":0.8190000057220459},{"id":"https://openalex.org/keywords/renal-ischemia-reperfusion-injury","display_name":"renal ischemia-reperfusion injury","score":0.9940000176429749},{"id":"https://openalex.org/keywords/renal-protection","display_name":"renal protection","score":0.8450000286102295},{"id":"https://openalex.org/keywords/renal-ischemia","display_name":"renal ischemia","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.5110596418380737},{"id":"https://openalex.org/C2780114680","wikidata":"https://www.wikidata.org/wiki/Q1413991","display_name":"Reperfusion injury","level":3,"score":0.48990434408187866},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4728555679321289},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45038628578186035},{"id":"https://openalex.org/C2991844318","wikidata":"https://www.wikidata.org/wiki/Q476921","display_name":"Renal injury","level":3,"score":0.4405117928981781},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.342983603477478},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34140151739120483},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.25703155994415283}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.4274/nkmj.galenos.2023.74436","doi":"https://doi.org/10.4274/nkmj.galenos.2023.74436","is_oa":true,"landing_page_url":"https://doi.org/10.4274/nkmj.galenos.2023.74436","pdf_url":"https://doi.org/10.4274/nkmj.galenos.2023.74436","source":{"id":"https://openalex.org/S4210225446","display_name":"Nam\u0131k Kemal T\u0131p Dergisi","issn_l":"2587-0262","issn":["2587-0262"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nam\u0131k Kemal T\u0131p Dergisi","raw_type":"journal-article"},{"id":"pmh:7e764a98-cb87-4bc7-87f7-e8e9c8112f31","doi":null,"is_oa":false,"landing_page_url":"https://avesis.yyu.edu.tr/publication/details/7e764a98-cb87-4bc7-87f7-e8e9c8112f31/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055328","display_name":"Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Academic Data Management System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:855387a67c6f47b4930e2cb6c2a57296","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/855387a67c6f47b4930e2cb6c2a57296","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nam\u0131k Kemal T\u0131p Dergisi, Vol 11, Iss 3, Pp 284-293 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4274/nkmj.galenos.2023.74436","doi":"https://doi.org/10.4274/nkmj.galenos.2023.74436","is_oa":true,"landing_page_url":"https://doi.org/10.4274/nkmj.galenos.2023.74436","pdf_url":"https://doi.org/10.4274/nkmj.galenos.2023.74436","source":{"id":"https://openalex.org/S4210225446","display_name":"Nam\u0131k Kemal T\u0131p Dergisi","issn_l":"2587-0262","issn":["2587-0262"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nam\u0131k Kemal T\u0131p Dergisi","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386780751.pdf","grobid_xml":"https://content.openalex.org/works/W4386780751.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W7419881","https://openalex.org/W2011301426","https://openalex.org/W2052088499","https://openalex.org/W2086927107","https://openalex.org/W2094455358","https://openalex.org/W2130389986","https://openalex.org/W2138974722","https://openalex.org/W2166408662","https://openalex.org/W2167113024","https://openalex.org/W2268065170","https://openalex.org/W2329659234","https://openalex.org/W2342249984","https://openalex.org/W2592232824","https://openalex.org/W2604024577","https://openalex.org/W2725171488","https://openalex.org/W2741020202","https://openalex.org/W2777154445","https://openalex.org/W2799462250","https://openalex.org/W2896936273","https://openalex.org/W2905441841","https://openalex.org/W2908922193","https://openalex.org/W3009591208","https://openalex.org/W3010623149","https://openalex.org/W3012421329","https://openalex.org/W3035965352","https://openalex.org/W3048992632","https://openalex.org/W3121377667","https://openalex.org/W3126219419","https://openalex.org/W3144951232","https://openalex.org/W3199010552","https://openalex.org/W3214495208","https://openalex.org/W4211105116","https://openalex.org/W4213419707","https://openalex.org/W4281864799","https://openalex.org/W4285402895","https://openalex.org/W4292755595","https://openalex.org/W4307925723","https://openalex.org/W4309264281","https://openalex.org/W4312255555","https://openalex.org/W4324309277"],"related_works":["https://openalex.org/W2153916258","https://openalex.org/W4300017238","https://openalex.org/W2803687892","https://openalex.org/W2155182013","https://openalex.org/W2558123166","https://openalex.org/W1998158467","https://openalex.org/W2949400453","https://openalex.org/W2023965118","https://openalex.org/W2282258899","https://openalex.org/W2904013697"],"abstract_inverted_index":{"Effect":[0],"of":[1],"PDE":[2],"5":[3],"Inhibitor-Avanafil":[4],"on":[5],"Renal":[6],"Ischemia/Reperfusion":[7],"Injury":[8],"in":[9],"Rats":[10]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-09-16T00:00:00"}