{"id":"https://openalex.org/W4386775244","doi":"https://doi.org/10.1186/s12889-023-16681-w","title":"Mediating effects of DNA methylation in the association between sleep quality and infertility among women of childbearing age","display_name":"Mediating effects of DNA methylation in the association between sleep quality and infertility among women of childbearing age","publication_year":2023,"publication_date":"2023-09-15","ids":{"openalex":"https://openalex.org/W4386775244","doi":"https://doi.org/10.1186/s12889-023-16681-w","pmid":"https://pubmed.ncbi.nlm.nih.gov/37715240","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10503064"},"language":"en","primary_location":{"id":"doi:10.1186/s12889-023-16681-w","doi":"https://doi.org/10.1186/s12889-023-16681-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12889-023-16681-w","pdf_url":"https://bmcpublichealth.biomedcentral.com/counter/pdf/10.1186/s12889-023-16681-w","source":{"id":"https://openalex.org/S200437886","display_name":"BMC Public Health","issn_l":"1471-2458","issn":["1471-2458"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Public Health","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcpublichealth.biomedcentral.com/counter/pdf/10.1186/s12889-023-16681-w","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107869976","display_name":"Ying Tang","orcid":"https://orcid.org/0000-0001-9472-3047","observed_orcids":["https://orcid.org/0000-0001-9472-3047"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Tang","raw_affiliation_strings":["Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]},{"raw_affiliation_string":"NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108828657","display_name":"Hong Gan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Gan","raw_affiliation_strings":["Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]},{"raw_affiliation_string":"NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100648293","display_name":"Baolin Wang","orcid":"https://orcid.org/0000-0001-9758-4134","observed_orcids":["https://orcid.org/0000-0001-9758-4134"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baolin Wang","raw_affiliation_strings":["Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]},{"raw_affiliation_string":"NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100658022","display_name":"Xiaorui Wang","orcid":"https://orcid.org/0000-0002-5142-8264","observed_orcids":["https://orcid.org/0000-0002-5142-8264"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaorui Wang","raw_affiliation_strings":["Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060320154","display_name":"Mengdie Li","orcid":"https://orcid.org/0000-0001-8730-5138","observed_orcids":["https://orcid.org/0000-0001-8730-5138","https://orcid.org/0000-0001-9407-3769"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengdie Li","raw_affiliation_strings":["Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058718502","display_name":"Qianhui Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianhui Yang","raw_affiliation_strings":["Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072060453","display_name":"Menglong Geng","orcid":"https://orcid.org/0000-0003-3252-1460","observed_orcids":["https://orcid.org/0000-0003-3252-1460"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Menglong Geng","raw_affiliation_strings":["Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091007187","display_name":"Peng Zhu","orcid":"https://orcid.org/0000-0002-3502-5131","observed_orcids":["https://orcid.org/0000-0002-3502-5131","https://orcid.org/0000-0002-9356-6104"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Zhu","raw_affiliation_strings":["Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]},{"raw_affiliation_string":"NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067471487","display_name":"Shanshan Shao","orcid":"https://orcid.org/0000-0001-6732-3945","observed_orcids":["https://orcid.org/0000-0001-6732-3945"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shanshan Shao","raw_affiliation_strings":["Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]},{"raw_affiliation_string":"NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010865043","display_name":"Fangbiao Tao","orcid":"https://orcid.org/0000-0003-4807-9670","observed_orcids":["https://orcid.org/0000-0003-4807-9670"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Fangbiao Tao","raw_affiliation_strings":["Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China. taofangbiao@126.com","Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China. taofangbiao@126.com","MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China. taofangbiao@126.com","NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China. taofangbiao@126.com","MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No 81 Meishan Road, Hefei, 230032, Anhui, China. taofangbiao@126.com","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China. taofangbiao@126.com","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China. taofangbiao@126.com","institution_ids":[]},{"raw_affiliation_string":"NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, No 81 Meishan Road, Hefei, 230032, Anhui, China. taofangbiao@126.com","institution_ids":[]},{"raw_affiliation_string":"MOE Key Laboratory of Population Health Across Life Cycle, No 81 Meishan Road, Hefei, 230032, Anhui, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5010865043"],"corresponding_institution_ids":["https://openalex.org/I197869895"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":0.7095,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.63965256,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"23","issue":"1","first_page":"1802","last_page":"1802"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.7002000212669373,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.7002000212669373,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.19449999928474426,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.03269999846816063,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sleep-quality","display_name":"sleep quality","score":0.9860000014305115},{"id":"https://openalex.org/keywords/female-infertility","display_name":"female infertility","score":0.9660000205039978},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.9419999718666077},{"id":"https://openalex.org/keywords/mediating-effect","display_name":"mediating effect","score":0.722000002861023},{"id":"https://openalex.org/keywords/difficulty-falling-asleep","display_name":"difficulty falling asleep","score":0.921999990940094},{"id":"https://openalex.org/keywords/anovulatory-infertility","display_name":"anovulatory infertility","score":0.9539999961853027},{"id":"https://openalex.org/keywords/differentially-methylated-cpgs","display_name":"differentially methylated CpGs","score":0.925000011920929},{"id":"https://openalex.org/keywords/women-of-reproductive-age","display_name":"women of reproductive age","score":0.8069999814033508}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.8121311664581299},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.6694427132606506},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.655178964138031},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.5849738121032715},{"id":"https://openalex.org/C2777338322","wikidata":"https://www.wikidata.org/wiki/Q280156","display_name":"Male infertility","level":4,"score":0.5383798480033875},{"id":"https://openalex.org/C179420905","wikidata":"https://www.wikidata.org/wiki/Q223871","display_name":"Mediation","level":2,"score":0.4991800785064697},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4536149501800537},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.36707574129104614},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3548091650009155},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.337036669254303},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29828113317489624},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.26443588733673096},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17329800128936768},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16357624530792236},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.058663517236709595},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.056488752365112305},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000089943","descriptor_name":"Sleep Quality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007246","descriptor_name":"Infertility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12889-023-16681-w","doi":"https://doi.org/10.1186/s12889-023-16681-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12889-023-16681-w","pdf_url":"https://bmcpublichealth.biomedcentral.com/counter/pdf/10.1186/s12889-023-16681-w","source":{"id":"https://openalex.org/S200437886","display_name":"BMC Public Health","issn_l":"1471-2458","issn":["1471-2458"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Public Health","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-2634253/v1","doi":"https://doi.org/10.21203/rs.3.rs-2634253/v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.21203/rs.3.rs-2634253/v1","pdf_url":"https://www.researchsquare.com/article/rs-2634253/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10503064","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10503064","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10503064/pdf/12889_2023_Article_16681.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Public Health","raw_type":"Text"},{"id":"pmid:37715240","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37715240","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC public health","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:cceab96434c6429c973191ee8b748c3c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cceab96434c6429c973191ee8b748c3c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12889-023-16681-w","doi":"https://doi.org/10.1186/s12889-023-16681-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12889-023-16681-w","pdf_url":"https://bmcpublichealth.biomedcentral.com/counter/pdf/10.1186/s12889-023-16681-w","source":{"id":"https://openalex.org/S200437886","display_name":"BMC Public Health","issn_l":"1471-2458","issn":["1471-2458"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Public Health","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386775244.pdf","grobid_xml":"https://content.openalex.org/works/W4386775244.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W197066864","https://openalex.org/W1491258390","https://openalex.org/W1974241687","https://openalex.org/W1997866877","https://openalex.org/W2010860867","https://openalex.org/W2092516139","https://openalex.org/W2121417064","https://openalex.org/W2126705408","https://openalex.org/W2130523009","https://openalex.org/W2156383880","https://openalex.org/W2158269238","https://openalex.org/W2163166459","https://openalex.org/W2163327652","https://openalex.org/W2169556367","https://openalex.org/W2316624360","https://openalex.org/W2338381486","https://openalex.org/W2418575920","https://openalex.org/W2473841348","https://openalex.org/W2737045159","https://openalex.org/W2792279401","https://openalex.org/W2794604852","https://openalex.org/W2800569548","https://openalex.org/W2885284324","https://openalex.org/W2903970819","https://openalex.org/W2911308268","https://openalex.org/W2921467979","https://openalex.org/W2922067142","https://openalex.org/W2923948464","https://openalex.org/W2937103894","https://openalex.org/W2937265571","https://openalex.org/W2971188513","https://openalex.org/W2974802259","https://openalex.org/W2978766119","https://openalex.org/W2990195975","https://openalex.org/W2992920422","https://openalex.org/W2994745890","https://openalex.org/W3007708322","https://openalex.org/W3008145964","https://openalex.org/W3023345615","https://openalex.org/W3028881087","https://openalex.org/W3029066469","https://openalex.org/W3029388994","https://openalex.org/W3121563009","https://openalex.org/W3126680986","https://openalex.org/W3152924150","https://openalex.org/W3165233943","https://openalex.org/W3174685447","https://openalex.org/W3179296442","https://openalex.org/W3183012089","https://openalex.org/W3192355053","https://openalex.org/W4281258302","https://openalex.org/W4315433880"],"related_works":["https://openalex.org/W6902083723","https://openalex.org/W4388901455","https://openalex.org/W2898334176","https://openalex.org/W4411382424","https://openalex.org/W7221447580","https://openalex.org/W3080399783","https://openalex.org/W7129261915","https://openalex.org/W2770560784","https://openalex.org/W2752875130","https://openalex.org/W2620044618"],"abstract_inverted_index":{"BACKGROUND:":[0],"This":[1,28],"study":[2,29],"aims":[3],"to":[4,16,165,223,252,272,302],"investigate":[5],"the":[6,18,68,85,105,111,129,138,211,214,239,256,275],"association":[7],"between":[8,37,78,95,241],"sleep":[9,38,96],"quality":[10,39,97],"and":[11,15,40,52,80,98,131,188,210,245,264,278,292,295,304],"infertility":[12,41,48,99,178,246,265],"among":[13,100],"women":[14,45,101,120,139,180],"explore":[17],"mediating":[19,90,200],"effects":[20],"of":[21,92,121,137,159,193,213,255,282],"DNA":[22,59,93,194,230,287],"methylation":[23,60,94,195,220,231,288],"in":[24,44,128,179,238,247,266],"this":[25,219],"association.":[26],"METHODS:":[27],"is":[30],"a":[31,174,189,235],"population-based":[32],"case-control":[33],"study.":[34],"The":[35,89,116,134,199,285],"relationship":[36,240],"was":[42,61,102,140,173,197,205],"investigated":[43,103],"with":[46,124],"anovulatory":[47],"(n":[49,55],"=":[50,56,182,185,208],"43)":[51],"healthy":[53],"controls":[54,81],"43).":[57],"Genome-wide":[58],"profiled":[62],"from":[63],"peripheral":[64],"blood":[65],"samples":[66],"using":[67,84,104],"Illumina":[69],"Infinium":[70],"Human":[71],"Methylation":[72],"850k":[73],"BeadChip.":[74],"Differentially":[75],"methylated":[76,162],"CpGs":[77,163,196,232],"cases":[79],"were":[82,168],"identified":[83,286],"ChAMP":[86],"R":[87,112],"package.":[88],"effect":[91,192,201,216],"Bayesian":[106],"estimation":[107],"method":[108],"provided":[109],"by":[110,218],"package":[113],"\"mediation\".":[114],"RESULTS:":[115],"survey":[117],"included":[118],"86":[119],"reproductive":[122],"age,":[123],"43":[125],"participants":[126],"each":[127],"case":[130],"control":[132,151],"groups.":[133],"average":[135],"age":[136],"27.6":[141],"\u00b1":[142,148,154],"2.8":[143],"years":[144],"(case":[145],"group:":[146,152],"27.8":[147],"3.0":[149],"years,":[150],"27.4":[153],"2.7":[155],"years).":[156],"A":[157],"total":[158,215],"262":[160],"differentially":[161],"corresponding":[164],"185":[166],"genes":[167],"identified.":[169],"Difficulty":[170],"falling":[171,243,262],"asleep":[172,244,263],"risk":[175],"factor":[176],"for":[177,203,298],"(OR":[181],"3.69,":[183],"95%CI":[184],"1.14,":[186],"11.99),":[187],"causal":[190],"mediation":[191],"found.":[198],"coefficient":[202],"cg08298632":[204],"0.10":[206],"(95%CI":[207],"0.01-0.22),":[209],"proportion":[212],"mediated":[217],"site":[221],"increased":[222],"64.3%.":[224],"CONCLUSION:":[225],"These":[226,249],"results":[227],"suggest":[228],"that":[229,259],"(cg08298632)":[233],"play":[234],"significant":[236],"role":[237],"difficulty":[242,261],"females.":[248],"findings":[250],"contribute":[251],"our":[253],"understanding":[254],"underlying":[257],"mechanisms":[258],"connect":[260],"women.":[267],"Further":[268],"studies":[269,300],"are":[270],"necessary":[271],"fully":[273],"understand":[274],"biological":[276],"significance":[277],"potential":[279,296],"therapeutic":[280],"applications":[281],"these":[283],"findings.":[284],"sites":[289],"provide":[290],"new":[291],"valuable":[293],"insights":[294],"targets":[297],"future":[299],"aiming":[301],"prevent":[303],"treat":[305],"female":[306],"infertility.":[307]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-09-16T00:00:00"}