{"id":"https://openalex.org/W4386567992","doi":"https://doi.org/10.17816/vto322787","title":"Long-term results of periprosthetic infection prevention and treatment in oncoorthopedics","display_name":"Long-term results of periprosthetic infection prevention and treatment in oncoorthopedics","publication_year":2023,"publication_date":"2023-09-09","ids":{"openalex":"https://openalex.org/W4386567992","doi":"https://doi.org/10.17816/vto322787"},"language":"en","primary_location":{"id":"doi:10.17816/vto322787","doi":"https://doi.org/10.17816/vto322787","is_oa":true,"landing_page_url":"https://doi.org/10.17816/vto322787","pdf_url":"https://journals.eco-vector.com/0869-8678/article/download/322787/pdf_3","source":{"id":"https://openalex.org/S4210236349","display_name":"N N Priorov Journal of Traumatology and Orthopedics","issn_l":"0869-8678","issn":["0869-8678","2658-6738"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":"https://openalex.org/P4310312788","host_organization_name":"ECO-vector","host_organization_lineage":["https://openalex.org/P4310312788"],"host_organization_lineage_names":["ECO-vector"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"N.N. Priorov Journal of Traumatology and Orthopedics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://journals.eco-vector.com/0869-8678/article/download/322787/pdf_3","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000053618","display_name":"\u0410. \u0412. \u0421\u043e\u043a\u043e\u043b\u043e\u0432\u0441\u043a\u0438\u0439","orcid":"https://orcid.org/0000-0002-8181-019X","observed_orcids":["https://orcid.org/0000-0002-8181-019X"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Anatolii V. Sokolovskii","raw_affiliation_strings":["Blokhin National Medical Research Center of Oncology"],"raw_orcid":"https://orcid.org/0000-0002-8181-019X","affiliations":[{"raw_affiliation_string":"Blokhin National Medical Research Center of Oncology","institution_ids":["https://openalex.org/I4210090957"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013760366","display_name":"Vladimir A. Sokolovskii","orcid":"https://orcid.org/0000-0003-0558-4466","observed_orcids":["https://orcid.org/0000-0003-0558-4466"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Vladimir A. Sokolovskii","raw_affiliation_strings":["Blokhin National Medical Research Center of Oncology","\u041d\u0430\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u044b\u0439 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0439 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u0438\u0439 \u0446\u0435\u043d\u0442\u0440 \u043e\u043d\u043a\u043e\u043b\u043e\u0433\u0438\u0438 \u0438\u043c. \u041d.\u041d. \u0411\u043b\u043e\u0445\u0438\u043d\u0430"],"raw_orcid":"https://orcid.org/0000-0003-0558-4466","affiliations":[{"raw_affiliation_string":"Blokhin National Medical Research Center of Oncology","institution_ids":["https://openalex.org/I4210090957"]},{"raw_affiliation_string":"\u041d\u0430\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u044b\u0439 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0439 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u0438\u0439 \u0446\u0435\u043d\u0442\u0440 \u043e\u043d\u043a\u043e\u043b\u043e\u0433\u0438\u0438 \u0438\u043c. \u041d.\u041d. \u0411\u043b\u043e\u0445\u0438\u043d\u0430","institution_ids":["https://openalex.org/I4210090957"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007194059","display_name":"Gennady N. Machak","orcid":"https://orcid.org/0000-0003-1222-5066","observed_orcids":["https://orcid.org/0000-0003-1222-5066"]},"institutions":[{"id":"https://openalex.org/I4210109445","display_name":"Central Scientific Research Institute of Traumatology and Orthopedics","ror":"https://ror.org/022d6m891","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210109445"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Gennady N. Machak","raw_affiliation_strings":["Priorov National Medical Research Center of Traumatology and Orthopedics"],"raw_orcid":"https://orcid.org/0000-0003-1222-5066","affiliations":[{"raw_affiliation_string":"Priorov National Medical Research Center of Traumatology and Orthopedics","institution_ids":["https://openalex.org/I4210109445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080259151","display_name":"\u041f\u0435\u0442\u0443\u0445\u043e\u0432\u0430 \u0418\u0440\u0438\u043d\u0430 \u041d\u0438\u043a\u043e\u043b\u0430\u0435\u0432\u043d\u0430","orcid":"https://orcid.org/0000-0003-3077-0447","observed_orcids":["https://orcid.org/0000-0003-3077-0447"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Irina N. Petukhova","raw_affiliation_strings":["Blokhin National Medical Research Center of Oncology"],"raw_orcid":"https://orcid.org/0000-0003-3077-0447","affiliations":[{"raw_affiliation_string":"Blokhin National Medical Research Center of Oncology","institution_ids":["https://openalex.org/I4210090957"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028190313","display_name":"Aleksandr A. Kurilchik","orcid":"https://orcid.org/0000-0003-2615-078X","observed_orcids":["https://orcid.org/0000-0003-2615-078X"]},"institutions":[{"id":"https://openalex.org/I4210117327","display_name":"Medical Radiological Research Center","ror":"https://ror.org/02dr19631","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210117327"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Alexander A. Kurilchik","raw_affiliation_strings":["Tsyba Medical Radiological Research Center"],"raw_orcid":"https://orcid.org/0000-0003-2615-078X","affiliations":[{"raw_affiliation_string":"Tsyba Medical Radiological Research Center","institution_ids":["https://openalex.org/I4210117327"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111037351","display_name":"Alexander A. Geravin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150189","display_name":"Meshalkin National Medical Research Center","ror":"https://ror.org/04jm2zr28","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210150189"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Alexander A. Geravin","raw_affiliation_strings":["Meshalkin National Medical Research Center of Oncology"],"raw_orcid":"https://orcid.org/0000-0003-3169-0326","affiliations":[{"raw_affiliation_string":"Meshalkin National Medical Research Center of Oncology","institution_ids":["https://openalex.org/I4210150189"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2136,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.43408584,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"30","issue":"2","first_page":"143","last_page":"159"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11293","display_name":"Orthopedic Infections and Treatments","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11293","display_name":"Orthopedic Infections and Treatments","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/periprosthetic-joint-infection","display_name":"periprosthetic joint infection","score":0.949999988079071},{"id":"https://openalex.org/keywords/infection-control","display_name":"infection control","score":0.5},{"id":"https://openalex.org/keywords/recurrent-infections","display_name":"recurrent infections","score":0.4169999957084656},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.8309999704360962},{"id":"https://openalex.org/keywords/staphylococcus-epidermidis","display_name":"Staphylococcus epidermidis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bone-metastases","display_name":"bone metastasis","score":0.44200000166893005},{"id":"https://openalex.org/keywords/soft-tissue-sarcoma","display_name":"soft tissue sarcoma","score":0.6320000290870667},{"id":"https://openalex.org/keywords/bone-sarcoma","display_name":"bone sarcoma","score":0.597000002861023},{"id":"https://openalex.org/keywords/long-term-outcomes","display_name":"long-term outcomes","score":0.7009999752044678},{"id":"https://openalex.org/keywords/antibiotic-prophylaxis","display_name":"antibiotic prophylaxis","score":0.5180000066757202}],"concepts":[{"id":"https://openalex.org/C2778120723","wikidata":"https://www.wikidata.org/wiki/Q16872681","display_name":"Periprosthetic","level":3,"score":0.8656952381134033},{"id":"https://openalex.org/C61797465","wikidata":"https://www.wikidata.org/wiki/Q1188986","display_name":"Term (time)","level":2,"score":0.7317860126495361},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5663654208183289},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2772270143032074},{"id":"https://openalex.org/C2778336525","wikidata":"https://www.wikidata.org/wiki/Q708178","display_name":"Arthroplasty","level":2,"score":0.2151680588722229},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.04767271876335144},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.17816/vto322787","doi":"https://doi.org/10.17816/vto322787","is_oa":true,"landing_page_url":"https://doi.org/10.17816/vto322787","pdf_url":"https://journals.eco-vector.com/0869-8678/article/download/322787/pdf_3","source":{"id":"https://openalex.org/S4210236349","display_name":"N N Priorov Journal of Traumatology and Orthopedics","issn_l":"0869-8678","issn":["0869-8678","2658-6738"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":"https://openalex.org/P4310312788","host_organization_name":"ECO-vector","host_organization_lineage":["https://openalex.org/P4310312788"],"host_organization_lineage_names":["ECO-vector"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"N.N. Priorov Journal of Traumatology and Orthopedics","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.17816/vto322787","doi":"https://doi.org/10.17816/vto322787","is_oa":true,"landing_page_url":"https://doi.org/10.17816/vto322787","pdf_url":"https://journals.eco-vector.com/0869-8678/article/download/322787/pdf_3","source":{"id":"https://openalex.org/S4210236349","display_name":"N N Priorov Journal of Traumatology and Orthopedics","issn_l":"0869-8678","issn":["0869-8678","2658-6738"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":"https://openalex.org/P4310312788","host_organization_name":"ECO-vector","host_organization_lineage":["https://openalex.org/P4310312788"],"host_organization_lineage_names":["ECO-vector"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"N.N. Priorov Journal of Traumatology and Orthopedics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386567992.pdf","grobid_xml":"https://content.openalex.org/works/W4386567992.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1577673004","https://openalex.org/W1907934764","https://openalex.org/W1971207038","https://openalex.org/W1981161611","https://openalex.org/W1991065463","https://openalex.org/W1996368662","https://openalex.org/W1998371141","https://openalex.org/W2017342294","https://openalex.org/W2019804131","https://openalex.org/W2034320092","https://openalex.org/W2038186111","https://openalex.org/W2041067795","https://openalex.org/W2047634313","https://openalex.org/W2049146717","https://openalex.org/W2051117700","https://openalex.org/W2071491784","https://openalex.org/W2077256650","https://openalex.org/W2102037222","https://openalex.org/W2119411177","https://openalex.org/W2136454327","https://openalex.org/W2140609535","https://openalex.org/W2160233281","https://openalex.org/W2284524567","https://openalex.org/W2324962950","https://openalex.org/W2398189693","https://openalex.org/W2817219343","https://openalex.org/W2883137154"],"related_works":["https://openalex.org/W2169228791","https://openalex.org/W2398189693","https://openalex.org/W4243022462","https://openalex.org/W4416318845","https://openalex.org/W4318485328","https://openalex.org/W4223933915","https://openalex.org/W2535348877","https://openalex.org/W4386210807","https://openalex.org/W4361007724","https://openalex.org/W1976665054"],"abstract_inverted_index":{"BACKGROUND:":[0],"Endoprosthesis":[1,26],"after":[2,57,185,288,300,315,322],"bone":[3,16,27,110,118,173,190],"and":[4,30,64,71,116,124,131,140,175,213,263,271,277,293,352,376],"joint":[5],"resection":[6],"is":[7],"the":[8,34,52,58,73,146,204,228,247,332,339,342,371,377,381,400,416],"treatment":[9,63,77,391,418],"of":[10,21,47,54,60,76,93,136,200,221,239,252,320,341,374,384],"choice":[11],"for":[12,420],"patients":[13,79,107,165],"with":[14,33,80,108,166,171,178,188,380],"malignant":[15],"tumors,":[17],"especially":[18],"in":[19,78,145,150,162,208,214,224,233,246,274,318,325,331,349,355],"case":[20],"a":[22,90,366,405],"favorable":[23],"oncological":[24],"prognosis.":[25,67],"site":[28,344,386],"infection":[29,49,83,202,223,241,346,388],"relapse":[31],"associated":[32,379],"underlying":[35],"disease":[36],"are":[37,41],"important":[38],"complications":[39,261,269],"that":[40,411],"difficult":[42],"to":[43,51,88,155,257,311,337,393,398,404],"treat.":[44],"The":[45,103,181,198,218,237,250,327,359,408],"development":[46],"periprosthetic":[48,82,98,201,240,313,421],"leads":[50],"loss":[53],"functional":[55],"potential":[56],"end":[59],"this":[61],"complication":[62],"worsens":[65],"oncologic":[66,86],"AIM:":[68],"To":[69],"study":[70,104,333],"improve":[72],"long-term":[74],"results":[75],"diagnosed":[81],"who":[84,120],"underwent":[85,121],"endoprosthesis,":[87],"develop":[89],"preventive":[91,328],"complex":[92],"measures":[94,329],"aimed":[95],"at":[96],"reducing":[97],"infection.":[99,422],"MATERIAL":[100],"AND":[101],"METHODS:":[102],"included":[105],"1292":[106],"primary":[109,123,167,209,225,276,289,316,350],"sarcomas,":[111,114],"soft":[112],"tissue":[113],"metastatic":[115,172],"benign":[117,179],"tumors":[119],"1671":[122],"recurrent":[125],"endoprosthetic":[126,186,248,290,302],"replacements":[127],"between":[128],"January":[129,132],"1992":[130],"2020.":[133],"A":[134],"total":[135],"677":[137],"(52.4%)":[138],"men":[139],"615":[141],"(47.6%)":[142],"women":[143],"participated":[144],"study.":[147],"Patients":[148],"ranged":[149],"age":[151],"from":[152],"10":[153],"years":[154],"81":[156],"years.":[157],"Oncologic":[158],"endoprosthetics":[159],"were":[160],"performed":[161],"886":[163],"(68.6%)":[164],"malignancies,":[168],"144":[169],"(11.1%)":[170],"lesions,":[174],"262":[176],"(20.3%)":[177],"neoplasms.":[180],"mean":[182],"follow-up":[183,206],"period":[184,207,230],"replacement":[187,291,303,414],"various":[189],"segments":[191],"was":[192,211,231,242,280,284,296,307],"82.8":[193],"months":[194],"(0-335.7":[195],"months).":[196],"RESULTS:":[197],"incidence":[199,340],"during":[203,227,370],"entire":[205,372],"endoprosthesis":[210,216,222,226,235,317,324,343,351,385],"7.1%,":[212],"repeat":[215,234,278,301,323,356],"6.2%.":[217],"recurrence":[219],"rate":[220],"observation":[229],"83%,":[232],"61.5%.":[236],"frequency":[238],"reduced":[243],"by":[244,347,353],"changes":[245],"strategy.":[249],"prevalence":[251],"early":[253,345,387],"(type":[254,267],"IVA":[255],"according":[256],"ISOLS":[258],"2013)":[259],"infectious":[260],"(15":[262],"11.9%)":[264],"over":[265],"late":[266],"IVB)":[268],"(5":[270],"4.4%,":[272],"respectively)":[273],"both":[275],"arthroplasty":[279],"higher.":[281],"Staphylococcus":[282,294],"aureus":[283],"most":[285,297,309],"frequently":[286],"identified":[287],"(38.1%)":[292],"epidermidis":[295],"commonly":[298],"verified":[299],"(53%).":[304],"Two-stage":[305],"reendoprosthesis":[306],"used":[308],"often":[310],"treat":[312],"infection:":[314],"58.3%":[319],"cases,":[321],"65.4%.":[326],"developed":[330],"made":[334],"it":[335],"possible":[336],"reduce":[338,399],"15.3%":[348],"7.1%":[354],"endoprosthesis.":[357],"CONCLUSION:":[358],"perioperative":[360],"antibiotic":[361,368,390],"prevention":[362],"regimen":[363],"should":[364],"provide":[365],"steady":[367],"concentration":[369],"course":[373],"surgery":[375],"time":[378],"highest":[382],"risk":[383],"(extended":[389],"up":[392],"5":[394],"days),":[395],"which":[396],"allows":[397],"wound":[401],"microbial":[402],"contamination":[403],"safe":[406],"level.":[407],"findings":[409],"suggest":[410],"two-stage":[412],"reendoprosthetic":[413],"remains":[415],"main":[417],"option":[419]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2023-09-10T00:00:00"}