{"id":"https://openalex.org/W4386537845","doi":"https://doi.org/10.1007/s12017-023-08754-1","title":"Dysregulated COMT Expression in Fragile X Syndrome","display_name":"Dysregulated COMT Expression in Fragile X Syndrome","publication_year":2023,"publication_date":"2023-09-08","ids":{"openalex":"https://openalex.org/W4386537845","doi":"https://doi.org/10.1007/s12017-023-08754-1","pmid":"https://pubmed.ncbi.nlm.nih.gov/37684514"},"language":"en","primary_location":{"id":"doi:10.1007/s12017-023-08754-1","doi":"https://doi.org/10.1007/s12017-023-08754-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12017-023-08754-1","pdf_url":null,"source":{"id":"https://openalex.org/S45104802","display_name":"NeuroMolecular Medicine","issn_l":"1535-1084","issn":["1535-1084","1559-1174"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroMolecular Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://researchprofiles.ku.dk/da/publications/9804562b-4660-4ae6-a4c7-afe6a8df407d","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006825753","display_name":"Kagistia Hana Utami","orcid":"https://orcid.org/0000-0002-7209-2253","observed_orcids":["https://orcid.org/0000-0002-7209-2253"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Kagistia Hana Utami","raw_affiliation_strings":["Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore","Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore","institution_ids":["https://openalex.org/I172675005"]},{"raw_affiliation_string":"Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore","institution_ids":["https://openalex.org/I115228651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087094554","display_name":"Nur Amirah Binte Mohammad Yusof","orcid":"https://orcid.org/0000-0002-0490-7617","observed_orcids":["https://orcid.org/0000-0002-0490-7617"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Nur Amirah Binte Muhammed Yusof","raw_affiliation_strings":["Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore","institution_ids":["https://openalex.org/I115228651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085184563","display_name":"Marta Garcia\u2010Miralles","orcid":"https://orcid.org/0000-0001-7250-5778","observed_orcids":["https://orcid.org/0000-0001-7250-5778"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE","SG"],"is_corresponding":false,"raw_author_name":"Marta Garcia-Miralles","raw_affiliation_strings":["Department of Molecular Embryology, Medical Faculty, Institute of Anatomy and Cell Biology, Albert-Ludwigs-University Freiburg, 79104, Freiburg, Germany","Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Embryology, Medical Faculty, Institute of Anatomy and Cell Biology, Albert-Ludwigs-University Freiburg, 79104, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore","institution_ids":["https://openalex.org/I115228651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054708177","display_name":"Niels Henning Skotte","orcid":"https://orcid.org/0000-0001-7027-7193","observed_orcids":["https://orcid.org/0000-0001-7027-7193"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Niels Henning Skotte","raw_affiliation_strings":["Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark","Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, 2200, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, 2200, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2801134892"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047412693","display_name":"Srikanth Nama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4210147916","display_name":"Institute of Medical Biology","ror":"https://ror.org/04frzv033","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I4210147916"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Srikanth Nama","raw_affiliation_strings":["Institute of Medical Biology, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Biology, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210147916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006228511","display_name":"Prabha Sampath","orcid":"https://orcid.org/0000-0001-8672-498X","observed_orcids":["https://orcid.org/0000-0001-8672-498X"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Prabha Sampath","raw_affiliation_strings":["Agency for Science, Technology and Research, Genome Institute of Singapore, 60 Biopolis Street, Genome, Singapore, 138672, Singapore","Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agency for Science, Technology and Research, Genome Institute of Singapore, 60 Biopolis Street, Genome, Singapore, 138672, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]},{"raw_affiliation_string":"Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore","institution_ids":["https://openalex.org/I4210126319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062596666","display_name":"Sarah R. Langley","orcid":"https://orcid.org/0000-0003-4419-476X","observed_orcids":["https://orcid.org/0000-0003-4419-476X"]},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]},{"id":"https://openalex.org/I79510175","display_name":"Cardiff University","ror":"https://ror.org/03kk7td41","country_code":"GB","type":"education","lineage":["https://openalex.org/I79510175"]}],"countries":["GB","SG"],"is_corresponding":false,"raw_author_name":"Sarah R. Langley","raw_affiliation_strings":["Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore","School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore","institution_ids":["https://openalex.org/I172675005"]},{"raw_affiliation_string":"School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK","institution_ids":["https://openalex.org/I79510175"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082965726","display_name":"Mahmoud A. Pouladi","orcid":"https://orcid.org/0000-0002-9030-0976","observed_orcids":["https://orcid.org/0000-0002-9030-0976"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I4405258907","display_name":"BC Children's Hospital Research Institute","ror":"https://ror.org/01cvasn76","country_code":"CA","type":"education","lineage":["https://openalex.org/I4210153200","https://openalex.org/I4405258907"]},{"id":"https://openalex.org/I4405270147","display_name":"Djavad Mowafaghian Centre for Brain Health","ror":"https://ror.org/005235b87","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4405270147"]}],"countries":["CA","SG"],"is_corresponding":true,"raw_author_name":"Mahmoud A. Pouladi","raw_affiliation_strings":["Department of Medical Genetics, Centre for Molecular Medicine & Therapeutics, Djavad Mowafaghian Centre for Brain Health, British Columbia Children's Hospital Research Institute, University of British Columbia, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada. mahmoud.pouladi@ubc.ca","Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore. mahmoud.pouladi@ubc.ca","Department of Medical Genetics, Centre for Molecular Medicine & Therapeutics, Djavad Mowafaghian Centre for Brain Health, British Columbia Children's Hospital Research Institute, University of British Columbia, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Genetics, Centre for Molecular Medicine & Therapeutics, Djavad Mowafaghian Centre for Brain Health, British Columbia Children's Hospital Research Institute, University of British Columbia, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada. mahmoud.pouladi@ubc.ca","institution_ids":["https://openalex.org/I141945490","https://openalex.org/I4405258907","https://openalex.org/I4405270147"]},{"raw_affiliation_string":"Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore, 138648, Singapore. mahmoud.pouladi@ubc.ca","institution_ids":["https://openalex.org/I115228651"]},{"raw_affiliation_string":"Department of Medical Genetics, Centre for Molecular Medicine & Therapeutics, Djavad Mowafaghian Centre for Brain Health, British Columbia Children's Hospital Research Institute, University of British Columbia, 950 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada","institution_ids":["https://openalex.org/I141945490","https://openalex.org/I4405258907","https://openalex.org/I4405270147"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5082965726"],"corresponding_institution_ids":["https://openalex.org/I115228651","https://openalex.org/I141945490","https://openalex.org/I4405258907","https://openalex.org/I4405270147"],"apc_list":{"value":4490,"currency":"USD","value_usd":4490},"apc_paid":null,"fwci":0.1241,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.36752376,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"25","issue":"4","first_page":"644","last_page":"649"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11015","display_name":"Down syndrome and intellectual disability research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fragile-x-syndrome","display_name":"fragile X syndrome","score":0.9829999804496765},{"id":"https://openalex.org/keywords/catechol-o-methyltransferase","display_name":"catechol-O-methyltransferase","score":0.9570000171661377},{"id":"https://openalex.org/keywords/fmrp","display_name":"FMRP","score":0.9509999752044678},{"id":"https://openalex.org/keywords/fmr1-knockout-mice","display_name":"Fmr1 knockout mice","score":0.8289999961853027},{"id":"https://openalex.org/keywords/dopaminergic-neurotransmission","display_name":"dopamine signaling","score":0.8180000185966492},{"id":"https://openalex.org/keywords/catecholamine-metabolism","display_name":"catecholamine metabolism","score":0.996999979019165},{"id":"https://openalex.org/keywords/neural-progenitor-cells","display_name":"neural progenitor cells","score":0.6959999799728394},{"id":"https://openalex.org/keywords/hippocampal-neurons","display_name":"hippocampal neurons","score":0.9810000061988831},{"id":"https://openalex.org/keywords/intellectual-disability","display_name":"intellectual disability","score":0.949999988079071},{"id":"https://openalex.org/keywords/autism-spectrum-disorder","display_name":"autism spectrum disorder","score":0.8169999718666077},{"id":"https://openalex.org/keywords/gene-expression-dysregulation","display_name":"gene expression dysregulation","score":0.7649999856948853}],"concepts":[{"id":"https://openalex.org/C2777630245","wikidata":"https://www.wikidata.org/wiki/Q221472","display_name":"Fragile X syndrome","level":2,"score":0.9068232774734497},{"id":"https://openalex.org/C2779063550","wikidata":"https://www.wikidata.org/wiki/Q905435","display_name":"FMR1","level":4,"score":0.8696335554122925},{"id":"https://openalex.org/C185361966","wikidata":"https://www.wikidata.org/wiki/Q94291140","display_name":"Catechol-O-methyl transferase","level":4,"score":0.6849112510681152},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.681698203086853},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5661724209785461},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.5439974069595337},{"id":"https://openalex.org/C551499885","wikidata":"https://www.wikidata.org/wiki/Q183560","display_name":"Intellectual disability","level":2,"score":0.4826946258544922},{"id":"https://openalex.org/C205778803","wikidata":"https://www.wikidata.org/wiki/Q38404","display_name":"Autism","level":2,"score":0.48077577352523804},{"id":"https://openalex.org/C2778538070","wikidata":"https://www.wikidata.org/wiki/Q1436063","display_name":"Autism spectrum disorder","level":3,"score":0.45292532444000244},{"id":"https://openalex.org/C2778514916","wikidata":"https://www.wikidata.org/wiki/Q186242","display_name":"Norepinephrine","level":3,"score":0.4499186873435974},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35538768768310547},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3548617959022522},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3402351140975952},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.33155500888824463},{"id":"https://openalex.org/C3020422209","wikidata":"https://www.wikidata.org/wiki/Q221472","display_name":"Fragile x","level":3,"score":0.2889867126941681},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2829262316226959},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.23210373520851135},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1837998330593109},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.1393066644668579},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002394","descriptor_name":"Catechol O-Methyltransferase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005600","descriptor_name":"Fragile X Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005600","descriptor_name":"Fragile X Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051860","descriptor_name":"Fragile X Messenger Ribonucleoprotein 1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051860","descriptor_name":"Fragile X Messenger Ribonucleoprotein 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1007/s12017-023-08754-1","doi":"https://doi.org/10.1007/s12017-023-08754-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12017-023-08754-1","pdf_url":null,"source":{"id":"https://openalex.org/S45104802","display_name":"NeuroMolecular Medicine","issn_l":"1535-1084","issn":["1535-1084","1559-1174"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroMolecular Medicine","raw_type":"journal-article"},{"id":"pmid:37684514","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37684514","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuromolecular medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire/9804562b-4660-4ae6-a4c7-afe6a8df407d","doi":null,"is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/9804562b-4660-4ae6-a4c7-afe6a8df407d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Utami, K H, Yusof, N A B M, Garcia-Miralles, M, Skotte, N H, Nama, S, Sampath, P, Langley, S R & Pouladi, M A 2023, 'Dysregulated COMT Expression in Fragile X Syndrome', NeuroMolecular Medicine, vol. 25, pp. 644\u2013649. https://doi.org/10.1007/s12017-023-08754-1","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:https://orca.cardiff.ac.uk:163150","doi":null,"is_oa":true,"landing_page_url":"https://orca.cardiff.ac.uk/id/eprint/163150/1/FXS%20COMT.pdf","pdf_url":"https://orca.cardiff.ac.uk/id/eprint/163150/1/FXS%20COMT.pdf","source":{"id":"https://openalex.org/S4306401195","display_name":"ORCA Online Research @Cardiff (Cardiff University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79510175","host_organization_name":"Cardiff University","host_organization_lineage":["https://openalex.org/I79510175"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:dr.ntu.edu.sg:10356/227674","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/10356/227674","pdf_url":null,"source":{"id":"https://openalex.org/S4306402609","display_name":"DR-NTU (Nanyang Technological University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I172675005","host_organization_name":"Nanyang Technological University","host_organization_lineage":["https://openalex.org/I172675005"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pure.atira.dk:openaire/9804562b-4660-4ae6-a4c7-afe6a8df407d","doi":null,"is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/9804562b-4660-4ae6-a4c7-afe6a8df407d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Utami, K H, Yusof, N A B M, Garcia-Miralles, M, Skotte, N H, Nama, S, Sampath, P, Langley, S R & Pouladi, M A 2023, 'Dysregulated COMT Expression in Fragile X Syndrome', NeuroMolecular Medicine, vol. 25, pp. 644\u2013649. https://doi.org/10.1007/s12017-023-08754-1","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306123","display_name":"FRAXA Research Foundation","ror":"https://ror.org/050apvm78"},{"id":"https://openalex.org/F4320313426","display_name":"BC Children's Hospital","ror":"https://ror.org/04n901w50"},{"id":"https://openalex.org/F4320319965","display_name":"Michael Smith Health Research BC","ror":"https://ror.org/020x39229"},{"id":"https://openalex.org/F4320332513","display_name":"Weill Cornell Medical College","ror":"https://ror.org/02r109517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386537845.pdf","grobid_xml":"https://content.openalex.org/works/W4386537845.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1482498530","https://openalex.org/W1607356988","https://openalex.org/W1964187476","https://openalex.org/W1975350815","https://openalex.org/W1979531090","https://openalex.org/W1991071819","https://openalex.org/W1994593489","https://openalex.org/W1996330474","https://openalex.org/W2003521501","https://openalex.org/W2050364492","https://openalex.org/W2052326665","https://openalex.org/W2060971721","https://openalex.org/W2064533408","https://openalex.org/W2089927164","https://openalex.org/W2105837661","https://openalex.org/W2136326305","https://openalex.org/W2332049018","https://openalex.org/W2626191380","https://openalex.org/W2759433538","https://openalex.org/W2797218669","https://openalex.org/W2965332398","https://openalex.org/W3010977830","https://openalex.org/W3024746958","https://openalex.org/W3031983723","https://openalex.org/W3082379018","https://openalex.org/W3094404394","https://openalex.org/W4210359332","https://openalex.org/W4311830414"],"related_works":["https://openalex.org/W2116214216","https://openalex.org/W2004390372","https://openalex.org/W7024053909","https://openalex.org/W4283746562","https://openalex.org/W4409759081","https://openalex.org/W2119715911","https://openalex.org/W1523697278","https://openalex.org/W7095953794","https://openalex.org/W7213401168","https://openalex.org/W7062214477"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-09-09T00:00:00"}