{"id":"https://openalex.org/W4386511684","doi":"https://doi.org/10.1186/s12943-023-01843-6","title":"The evolution and heterogeneity of neutrophils in cancers: origins, subsets, functions, orchestrations and clinical applications","display_name":"The evolution and heterogeneity of neutrophils in cancers: origins, subsets, functions, orchestrations and clinical applications","publication_year":2023,"publication_date":"2023-09-07","ids":{"openalex":"https://openalex.org/W4386511684","doi":"https://doi.org/10.1186/s12943-023-01843-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/37679744"},"language":"en","primary_location":{"id":"doi:10.1186/s12943-023-01843-6","doi":"https://doi.org/10.1186/s12943-023-01843-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12943-023-01843-6","pdf_url":"https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/s12943-023-01843-6","source":{"id":"https://openalex.org/S132829192","display_name":"Molecular Cancer","issn_l":"1476-4598","issn":["1476-4598"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/s12943-023-01843-6","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100765398","display_name":"Siyao Liu","orcid":"https://orcid.org/0009-0009-7131-2187","observed_orcids":["https://orcid.org/0009-0009-7131-2187"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Siyao Liu","raw_affiliation_strings":["Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101784378","display_name":"Wenchuan Wu","orcid":"https://orcid.org/0000-0002-8408-885X","observed_orcids":["https://orcid.org/0000-0002-8408-885X","https://orcid.org/0000-0001-6317-3417"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenchuan Wu","raw_affiliation_strings":["Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010719077","display_name":"Yueshan Du","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yueshan Du","raw_affiliation_strings":["Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036689552","display_name":"Hanlin Yin","orcid":"https://orcid.org/0000-0002-6622-4301","observed_orcids":["https://orcid.org/0000-0002-6622-4301"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hanlin Yin","raw_affiliation_strings":["Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048153190","display_name":"Qiangda Chen","orcid":"https://orcid.org/0000-0003-0428-5173","observed_orcids":["https://orcid.org/0000-0003-0428-5173"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiangda Chen","raw_affiliation_strings":["Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081535825","display_name":"Weisheng Yu","orcid":"https://orcid.org/0000-0002-6264-7200","observed_orcids":["https://orcid.org/0000-0002-6264-7200"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weisheng Yu","raw_affiliation_strings":["Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051338992","display_name":"Wenquan Wang","orcid":"https://orcid.org/0000-0002-7603-3437","observed_orcids":["https://orcid.org/0000-0002-7603-3437","https://orcid.org/0000-0002-4696-8098"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenquan Wang","raw_affiliation_strings":["Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001426192","display_name":"Jun Yu","orcid":"https://orcid.org/0000-0003-2006-758X","observed_orcids":["https://orcid.org/0000-0003-2006-758X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jun Yu","raw_affiliation_strings":["Departments of Medicine and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100322344","display_name":"Liang Liu","orcid":"https://orcid.org/0000-0001-8630-7430","observed_orcids":["https://orcid.org/0000-0001-8630-7430"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Liang Liu","raw_affiliation_strings":["Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. liu.liang@zs-hospital.sh.cn","Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. liu.liang@zs-hospital.sh.cn","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China. liu.liang@zs-hospital.sh.cn","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. liu.liang@zs-hospital.sh.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. liu.liang@zs-hospital.sh.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China. liu.liang@zs-hospital.sh.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037626265","display_name":"Wenhui Lou","orcid":"https://orcid.org/0000-0001-5820-6843","observed_orcids":["https://orcid.org/0000-0001-5820-6843","https://orcid.org/0000-0002-6976-2498"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wenhui Lou","raw_affiliation_strings":["Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. lou.wenhui@zs-hospital.sh.cn","Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. lou.wenhui@zs-hospital.sh.cn","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China. lou.wenhui@zs-hospital.sh.cn","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. lou.wenhui@zs-hospital.sh.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. lou.wenhui@zs-hospital.sh.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China. lou.wenhui@zs-hospital.sh.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053958827","display_name":"Ning Pu","orcid":"https://orcid.org/0000-0002-3123-493X","observed_orcids":["https://orcid.org/0000-0002-3123-493X"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ning Pu","raw_affiliation_strings":["Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. npu15@fudan.edu.cn","Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. npu15@fudan.edu.cn","Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China. npu15@fudan.edu.cn","Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. npu15@fudan.edu.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. npu15@fudan.edu.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032, P.R. China. npu15@fudan.edu.cn","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210127074"]},{"raw_affiliation_string":"Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4210127074"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5037626265","https://openalex.org/A5053958827","https://openalex.org/A5100322344"],"corresponding_institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4210127074"],"apc_list":{"value":4890,"currency":"USD","value_usd":4890},"apc_paid":{"value":4890,"currency":"USD","value_usd":4890},"fwci":7.5146,"has_fulltext":true,"cited_by_count":86,"citation_normalized_percentile":{"value":0.98446207,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"22","issue":"1","first_page":"148","last_page":"148"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12626","display_name":"Cancer, Stress, Anesthesia, and Immune Response","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neutrophils","display_name":"neutrophils","score":0.9359999895095825},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.8090000152587891},{"id":"https://openalex.org/keywords/neutrophil-heterogeneity","display_name":"neutrophil heterogeneity","score":0.984000027179718},{"id":"https://openalex.org/keywords/neutrophil-polarization","display_name":"neutrophil polarization","score":0.8019999861717224},{"id":"https://openalex.org/keywords/bone-marrow","display_name":"bone marrow","score":0.7519999742507935},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.7979999780654907}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7608774900436401},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.628321647644043},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.5035609602928162},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.49843907356262207},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.46326830983161926},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.45946526527404785},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.42183998227119446},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3587452173233032},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.14672699570655823},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11250203847885132}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12943-023-01843-6","doi":"https://doi.org/10.1186/s12943-023-01843-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12943-023-01843-6","pdf_url":"https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/s12943-023-01843-6","source":{"id":"https://openalex.org/S132829192","display_name":"Molecular Cancer","issn_l":"1476-4598","issn":["1476-4598"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Cancer","raw_type":"journal-article"},{"id":"pmid:37679744","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37679744","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular cancer","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10483725","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10483725","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10483725/pdf/12943_2023_Article_1843.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Mol Cancer","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:7dea28a86c3c45b7a0433f39ee8571fe","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7dea28a86c3c45b7a0433f39ee8571fe","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Cancer, Vol 22, Iss 1, Pp 1-21 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12943-023-01843-6","doi":"https://doi.org/10.1186/s12943-023-01843-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12943-023-01843-6","pdf_url":"https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/s12943-023-01843-6","source":{"id":"https://openalex.org/S132829192","display_name":"Molecular Cancer","issn_l":"1476-4598","issn":["1476-4598"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Responsible consumption and production","score":0.5400000214576721,"id":"https://metadata.un.org/sdg/12"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1721789603","display_name":null,"funder_award_id":"82103409","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4078057339","display_name":null,"funder_award_id":"2021M690037","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G7583500724","display_name":null,"funder_award_id":"82272929","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8108860492","display_name":null,"funder_award_id":"82273382","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G873473239","display_name":null,"funder_award_id":"23XD1400600","funder_id":"https://openalex.org/F4320335796","funder_display_name":"Program of Shanghai Academic Research Leader"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320321851","display_name":"Fudan University","ror":"https://ror.org/013q1eq08"},{"id":"https://openalex.org/F4320335796","display_name":"Program of Shanghai Academic Research Leader","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386511684.pdf","grobid_xml":"https://content.openalex.org/works/W4386511684.grobid-xml"},"referenced_works_count":214,"referenced_works":["https://openalex.org/W1107917109","https://openalex.org/W1546909751","https://openalex.org/W1561928773","https://openalex.org/W1969438318","https://openalex.org/W1976646654","https://openalex.org/W1982906652","https://openalex.org/W1991562400","https://openalex.org/W1991615875","https://openalex.org/W1996213381","https://openalex.org/W2001174010","https://openalex.org/W2002157461","https://openalex.org/W2005647807","https://openalex.org/W2014466662","https://openalex.org/W2019676650","https://openalex.org/W2027936095","https://openalex.org/W2032227357","https://openalex.org/W2032769992","https://openalex.org/W2033899321","https://openalex.org/W2036054943","https://openalex.org/W2036965973","https://openalex.org/W2040937550","https://openalex.org/W2044748328","https://openalex.org/W2054726751","https://openalex.org/W2055480917","https://openalex.org/W2059287796","https://openalex.org/W2062429797","https://openalex.org/W2069169522","https://openalex.org/W2070117107","https://openalex.org/W2070943369","https://openalex.org/W2084906660","https://openalex.org/W2086049503","https://openalex.org/W2094112735","https://openalex.org/W2098888044","https://openalex.org/W2104599968","https://openalex.org/W2107817883","https://openalex.org/W2109930846","https://openalex.org/W2110981938","https://openalex.org/W2112671019","https://openalex.org/W2113737833","https://openalex.org/W2122419529","https://openalex.org/W2125894404","https://openalex.org/W2132516902","https://openalex.org/W2133444342","https://openalex.org/W2135304449","https://openalex.org/W2137314442","https://openalex.org/W2143172913","https://openalex.org/W2147923982","https://openalex.org/W2151832198","https://openalex.org/W2152677909","https://openalex.org/W2154594040","https://openalex.org/W2155360682","https://openalex.org/W2158809810","https://openalex.org/W2159913536","https://openalex.org/W2166469044","https://openalex.org/W2169403306","https://openalex.org/W2174179366","https://openalex.org/W2175766278","https://openalex.org/W2186246196","https://openalex.org/W2193074466","https://openalex.org/W2237810057","https://openalex.org/W2283284501","https://openalex.org/W2285906858","https://openalex.org/W2292022254","https://openalex.org/W2297269808","https://openalex.org/W2298626553","https://openalex.org/W2317575649","https://openalex.org/W2322452457","https://openalex.org/W2337743285","https://openalex.org/W2340963408","https://openalex.org/W2340990804","https://openalex.org/W2399999257","https://openalex.org/W2411042699","https://openalex.org/W2411767313","https://openalex.org/W2416038770","https://openalex.org/W2474950788","https://openalex.org/W2478547083","https://openalex.org/W2482783327","https://openalex.org/W2490368150","https://openalex.org/W2509315794","https://openalex.org/W2515907404","https://openalex.org/W2522758415","https://openalex.org/W2537892258","https://openalex.org/W2570947205","https://openalex.org/W2579462828","https://openalex.org/W2582686270","https://openalex.org/W2594615455","https://openalex.org/W2719499442","https://openalex.org/W2731227355","https://openalex.org/W2745821917","https://openalex.org/W2748319539","https://openalex.org/W2750717426","https://openalex.org/W2751509160","https://openalex.org/W2755829954","https://openalex.org/W2756335804","https://openalex.org/W2762816177","https://openalex.org/W2763257724","https://openalex.org/W2766522579","https://openalex.org/W2768248213","https://openalex.org/W2769350174","https://openalex.org/W2771587821","https://openalex.org/W2772743814","https://openalex.org/W2773700550","https://openalex.org/W2775714903","https://openalex.org/W2782798328","https://openalex.org/W2783417222","https://openalex.org/W2787698240","https://openalex.org/W2787894829","https://openalex.org/W2794239706","https://openalex.org/W2794535033","https://openalex.org/W2797737805","https://openalex.org/W2797968236","https://openalex.org/W2800301895","https://openalex.org/W2801527818","https://openalex.org/W2808347790","https://openalex.org/W2808736826","https://openalex.org/W2811247652","https://openalex.org/W2886142748","https://openalex.org/W2888637358","https://openalex.org/W2888894833","https://openalex.org/W2888997885","https://openalex.org/W2889256987","https://openalex.org/W2895126364","https://openalex.org/W2895692081","https://openalex.org/W2911601413","https://openalex.org/W2912696928","https://openalex.org/W2912852672","https://openalex.org/W2913248654","https://openalex.org/W2915717782","https://openalex.org/W2916383095","https://openalex.org/W2923394609","https://openalex.org/W2935366665","https://openalex.org/W2936706033","https://openalex.org/W2946833774","https://openalex.org/W2947029606","https://openalex.org/W2947258513","https://openalex.org/W2948132055","https://openalex.org/W2948773008","https://openalex.org/W2954842895","https://openalex.org/W2955177546","https://openalex.org/W2962318845","https://openalex.org/W2969594122","https://openalex.org/W2970092081","https://openalex.org/W2970210098","https://openalex.org/W2971180845","https://openalex.org/W2981524284","https://openalex.org/W2982435457","https://openalex.org/W2986572941","https://openalex.org/W2998345757","https://openalex.org/W2999714391","https://openalex.org/W3000319768","https://openalex.org/W3016802219","https://openalex.org/W3020886383","https://openalex.org/W3034704108","https://openalex.org/W3035965283","https://openalex.org/W3036074479","https://openalex.org/W3039693333","https://openalex.org/W3044190151","https://openalex.org/W3044222890","https://openalex.org/W3049389667","https://openalex.org/W3075220616","https://openalex.org/W3080232735","https://openalex.org/W3081036059","https://openalex.org/W3082256626","https://openalex.org/W3082518026","https://openalex.org/W3083023871","https://openalex.org/W3083894199","https://openalex.org/W3087108180","https://openalex.org/W3093916434","https://openalex.org/W3096583666","https://openalex.org/W3097294586","https://openalex.org/W3110695610","https://openalex.org/W3115974950","https://openalex.org/W3120670329","https://openalex.org/W3124070407","https://openalex.org/W3126854146","https://openalex.org/W3127189019","https://openalex.org/W3127371144","https://openalex.org/W3133580603","https://openalex.org/W3144992645","https://openalex.org/W3153096965","https://openalex.org/W3158060001","https://openalex.org/W3162485228","https://openalex.org/W3163700488","https://openalex.org/W3168416770","https://openalex.org/W3175999847","https://openalex.org/W3176701035","https://openalex.org/W3180778035","https://openalex.org/W3189383967","https://openalex.org/W3207710409","https://openalex.org/W3208677499","https://openalex.org/W3214477800","https://openalex.org/W4200505571","https://openalex.org/W4205954020","https://openalex.org/W4210472745","https://openalex.org/W4210958129","https://openalex.org/W4210993647","https://openalex.org/W4211253912","https://openalex.org/W4212820509","https://openalex.org/W4221097818","https://openalex.org/W4225764500","https://openalex.org/W4229030785","https://openalex.org/W4229365571","https://openalex.org/W4281748563","https://openalex.org/W4283719060","https://openalex.org/W4285600182","https://openalex.org/W4293047711","https://openalex.org/W4294243416","https://openalex.org/W4299804849","https://openalex.org/W4306385729","https://openalex.org/W4307446864","https://openalex.org/W4308501732","https://openalex.org/W4308620781","https://openalex.org/W4310747256","https://openalex.org/W4361269840"],"related_works":["https://openalex.org/W2066136773","https://openalex.org/W2565121077","https://openalex.org/W1495541589","https://openalex.org/W1987802636","https://openalex.org/W2190283986","https://openalex.org/W2158827209","https://openalex.org/W2316042956","https://openalex.org/W4285733331","https://openalex.org/W2130166758","https://openalex.org/W3195238582"],"abstract_inverted_index":{"Neutrophils,":[0],"the":[1,29,40,52,60,73,86,94,104,129],"most":[2],"prevalent":[3],"innate":[4],"immune":[5],"cells":[6],"in":[7,13,20,37,51,81],"humans,":[8],"have":[9],"garnered":[10],"significant":[11],"attention":[12],"recent":[14],"years":[15],"due":[16],"to":[17,27,55,59],"their":[18,43,69],"involvement":[19],"cancer":[21,38],"progression.":[22],"This":[23],"comprehensive":[24],"review":[25],"aimed":[26],"elucidate":[28],"important":[30],"roles":[31],"and":[32,57,78,89,109],"underlying":[33],"mechanisms":[34],"of":[35,42,68,91,103,136],"neutrophils":[36,77,92,108,134],"from":[39,49],"perspective":[41],"whole":[44],"life":[45],"cycle,":[46],"tracking":[47],"them":[48],"development":[50],"bone":[53],"marrow":[54],"circulation":[56],"finally":[58],"tumor":[61],"microenvironment":[62],"(TME).":[63],"Based":[64],"on":[65],"an":[66,100],"understanding":[67],"heterogeneity,":[70],"we":[71,84,97,119],"described":[72],"relationship":[74,106],"between":[75,107],"abnormal":[76],"clinical":[79,110,114],"manifestations":[80],"cancer.":[82],"Specifically,":[83],"explored":[85],"function,":[87],"origin,":[88],"polarization":[90],"within":[93],"TME.":[95],"Furthermore,":[96],"also":[98],"undertook":[99],"extensive":[101],"analysis":[102],"intricate":[105],"management,":[111],"including":[112],"neutrophil-based":[113],"treatment":[115],"strategies.":[116],"In":[117],"conclusion,":[118],"firmly":[120],"assert":[121],"that":[122],"directing":[123],"future":[124],"research":[125],"endeavors":[126],"towards":[127],"comprehending":[128],"remarkable":[130],"heterogeneity":[131],"exhibited":[132],"by":[133],"is":[135],"paramount":[137],"importance.":[138]},"counts_by_year":[{"year":2026,"cited_by_count":19},{"year":2025,"cited_by_count":45},{"year":2024,"cited_by_count":22}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}
