{"id":"https://openalex.org/W4386424316","doi":"https://doi.org/10.1016/j.ajpath.2023.07.004","title":"Adolescence and the Microbiome","display_name":"Adolescence and the Microbiome","publication_year":2023,"publication_date":"2023-09-04","ids":{"openalex":"https://openalex.org/W4386424316","doi":"https://doi.org/10.1016/j.ajpath.2023.07.004","pmid":"https://pubmed.ncbi.nlm.nih.gov/37673331","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10699129"},"language":"en","primary_location":{"id":"doi:10.1016/j.ajpath.2023.07.004","doi":"https://doi.org/10.1016/j.ajpath.2023.07.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajpath.2023.07.004","pdf_url":"http://ajp.amjpathol.org/article/S0002944023003073/pdf","source":{"id":"https://openalex.org/S145577119","display_name":"American Journal Of Pathology","issn_l":"0002-9440","issn":["0002-9440","1525-2191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Pathology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://ajp.amjpathol.org/article/S0002944023003073/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Matthew D. Carson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew D. Carson","raw_affiliation_strings":["Departments of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084545012","display_name":"Caroline Westwater","orcid":"https://orcid.org/0000-0001-9329-2513","observed_orcids":["https://orcid.org/0000-0001-9329-2513"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caroline Westwater","raw_affiliation_strings":["Departments of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina; Department of Microbiology and Immunology, College of Medicine, Medical University of South Carolina, Charleston, South Carolina","Department of Microbiology and Immunology, College of Medicine, Medical University of South Carolina, Charleston, South Carolina","Departments of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina"],"raw_orcid":"https://orcid.org/0000-0001-9329-2513","affiliations":[{"raw_affiliation_string":"Departments of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina; Department of Microbiology and Immunology, College of Medicine, Medical University of South Carolina, Charleston, South Carolina","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, College of Medicine, Medical University of South Carolina, Charleston, South Carolina","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Departments of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066323693","display_name":"Chad M. Novince","orcid":"https://orcid.org/0000-0002-0318-7494","observed_orcids":["https://orcid.org/0000-0002-0318-7494"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Chad M. Novince","raw_affiliation_strings":["Departments of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina; Division of Endocrinology, Department of Pediatrics, College of Medicine, Medical University of South Carolina, Charleston, South Carolina; Division of Periodontics, Department of Stomatology, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina. Electronic address: novincec@musc.edu","Departments of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina","Division of Endocrinology, Department of Pediatrics, College of Medicine, Medical University of South Carolina, Charleston, South Carolina","Division of Periodontics, Department of Stomatology, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina"],"raw_orcid":"https://orcid.org/0000-0002-0318-7494","affiliations":[{"raw_affiliation_string":"Departments of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina; Division of Endocrinology, Department of Pediatrics, College of Medicine, Medical University of South Carolina, Charleston, South Carolina; Division of Periodontics, Department of Stomatology, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina. Electronic address: novincec@musc.edu","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Departments of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Division of Endocrinology, Department of Pediatrics, College of Medicine, Medical University of South Carolina, Charleston, South Carolina","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Division of Periodontics, Department of Stomatology, College of Dental Medicine, Medical University of South Carolina, Charleston, South Carolina","institution_ids":["https://openalex.org/I153297377"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5066323693"],"corresponding_institution_ids":["https://openalex.org/I153297377"],"apc_list":{"value":2800,"currency":"USD","value_usd":2800},"apc_paid":null,"fwci":1.0808,"has_fulltext":true,"cited_by_count":41,"citation_normalized_percentile":{"value":0.75792468,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"193","issue":"12","first_page":"1900","last_page":"1909"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9639999866485596},{"id":"https://openalex.org/keywords/adolescence","display_name":"adolescence","score":0.9739999771118164},{"id":"https://openalex.org/keywords/host-microbiota-interactions","display_name":"host-microbiota interactions","score":0.8309999704360962},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.8299999833106995},{"id":"https://openalex.org/keywords/cognition-and-behavior","display_name":"cognition and behavior","score":0.8429999947547913},{"id":"https://openalex.org/keywords/metabolism","display_name":"metabolism","score":0.824999988079071},{"id":"https://openalex.org/keywords/adiposity","display_name":"adiposity","score":0.9869999885559082},{"id":"https://openalex.org/keywords/skeletal-development","display_name":"skeletal development","score":0.9419999718666077},{"id":"https://openalex.org/keywords/bone-mass-accrual","display_name":"bone accrual","score":0.9850000143051147},{"id":"https://openalex.org/keywords/adolescent-development","display_name":"adolescent development","score":0.4729999899864197},{"id":"https://openalex.org/keywords/omics","display_name":"omics","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.7492483258247375},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.42433977127075195},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3810270428657532},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.35681188106536865},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.34247446060180664},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34163698554039},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2056502401828766}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008136","descriptor_name":"Longevity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064307","descriptor_name":"Microbiota","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ajpath.2023.07.004","doi":"https://doi.org/10.1016/j.ajpath.2023.07.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajpath.2023.07.004","pdf_url":"http://ajp.amjpathol.org/article/S0002944023003073/pdf","source":{"id":"https://openalex.org/S145577119","display_name":"American Journal Of Pathology","issn_l":"0002-9440","issn":["0002-9440","1525-2191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Pathology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10699129","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10699129","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10699129/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Pathol","raw_type":"Text"},{"id":"pmid:37673331","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37673331","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of pathology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.ajpath.2023.07.004","doi":"https://doi.org/10.1016/j.ajpath.2023.07.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajpath.2023.07.004","pdf_url":"http://ajp.amjpathol.org/article/S0002944023003073/pdf","source":{"id":"https://openalex.org/S145577119","display_name":"American Journal Of Pathology","issn_l":"0002-9440","issn":["0002-9440","1525-2191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Pathology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1995253973","display_name":"Age-Related Kynurenine Accumulation Impairs miRNA and Hdac Epigenetic Regulation of the SDF-1 Axis Resulting in Bone Loss","funder_award_id":"R01AG067510","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G5246833424","display_name":"Impact of Tetracycline Antibiotics on Skeletal Maturation","funder_award_id":"R01AR081488","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G6678196420","display_name":"Mechanistic probes to study the immune response in periodontal disease","funder_award_id":"R01DE029637","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G9000868966","display_name":"T-COHR: Training in Craniofacial and Oral Health Research","funder_award_id":"T32DE017551","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G9000892278","display_name":"COBRE in Digestive and Liver Disease","funder_award_id":"P20GM130457","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000913767","display_name":"MUSC Digestive Disease Research Core Center","funder_award_id":"P30DK123704","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386424316.pdf","grobid_xml":"https://content.openalex.org/works/W4386424316.grobid-xml"},"referenced_works_count":84,"referenced_works":["https://openalex.org/W1622629914","https://openalex.org/W1779530018","https://openalex.org/W1843449358","https://openalex.org/W1967446803","https://openalex.org/W1973688510","https://openalex.org/W1980471449","https://openalex.org/W1985151726","https://openalex.org/W2003836872","https://openalex.org/W2009625251","https://openalex.org/W2019515792","https://openalex.org/W2021681667","https://openalex.org/W2030091490","https://openalex.org/W2035378093","https://openalex.org/W2038217946","https://openalex.org/W2049389336","https://openalex.org/W2053039168","https://openalex.org/W2060139683","https://openalex.org/W2082520266","https://openalex.org/W2107369528","https://openalex.org/W2109113634","https://openalex.org/W2113822705","https://openalex.org/W2150381557","https://openalex.org/W2151277589","https://openalex.org/W2155897723","https://openalex.org/W2159856210","https://openalex.org/W2167062509","https://openalex.org/W2167519234","https://openalex.org/W2232220193","https://openalex.org/W2257516528","https://openalex.org/W2265634200","https://openalex.org/W2273595760","https://openalex.org/W2293993925","https://openalex.org/W2398894736","https://openalex.org/W2521009788","https://openalex.org/W2527872371","https://openalex.org/W2556090133","https://openalex.org/W2586134549","https://openalex.org/W2601727535","https://openalex.org/W2626195186","https://openalex.org/W2730267944","https://openalex.org/W2734745938","https://openalex.org/W2746155660","https://openalex.org/W2791651825","https://openalex.org/W2803790829","https://openalex.org/W2805302824","https://openalex.org/W2810098278","https://openalex.org/W2901898635","https://openalex.org/W2910559662","https://openalex.org/W2910570404","https://openalex.org/W2922310454","https://openalex.org/W2927031657","https://openalex.org/W2942148775","https://openalex.org/W2952949941","https://openalex.org/W2968724963","https://openalex.org/W2970686316","https://openalex.org/W2994943535","https://openalex.org/W2999000800","https://openalex.org/W3040245690","https://openalex.org/W3046742546","https://openalex.org/W3083241614","https://openalex.org/W3088203083","https://openalex.org/W3092327810","https://openalex.org/W3096067847","https://openalex.org/W3113489143","https://openalex.org/W3118787178","https://openalex.org/W3133138414","https://openalex.org/W3161237422","https://openalex.org/W3195347900","https://openalex.org/W3216068629","https://openalex.org/W4220890529","https://openalex.org/W4220916912","https://openalex.org/W4255839518","https://openalex.org/W4280592536","https://openalex.org/W4288702909","https://openalex.org/W4298132546","https://openalex.org/W4307054508","https://openalex.org/W4309663014","https://openalex.org/W4311624747","https://openalex.org/W4319335357","https://openalex.org/W4323032951","https://openalex.org/W4323657859","https://openalex.org/W4366817653","https://openalex.org/W4367842138","https://openalex.org/W4379052208"],"related_works":["https://openalex.org/W2911875511","https://openalex.org/W7207670458","https://openalex.org/W4401001493","https://openalex.org/W4281259105","https://openalex.org/W7037118193","https://openalex.org/W3175727144","https://openalex.org/W2970428830","https://openalex.org/W2096500845","https://openalex.org/W2903256598","https://openalex.org/W7202082482"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":21},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":11}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-09-05T00:00:00"}