{"id":"https://openalex.org/W4386413629","doi":"https://doi.org/10.1186/s12885-023-11347-7","title":"MALAT1-regulated gene expression profiling in lung cancer cell lines","display_name":"MALAT1-regulated gene expression profiling in lung cancer cell lines","publication_year":2023,"publication_date":"2023-09-04","ids":{"openalex":"https://openalex.org/W4386413629","doi":"https://doi.org/10.1186/s12885-023-11347-7","pmid":"https://pubmed.ncbi.nlm.nih.gov/37667226","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10476395"},"language":"en","primary_location":{"id":"doi:10.1186/s12885-023-11347-7","doi":"https://doi.org/10.1186/s12885-023-11347-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12885-023-11347-7","pdf_url":"https://bmccancer.biomedcentral.com/counter/pdf/10.1186/s12885-023-11347-7","source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmccancer.biomedcentral.com/counter/pdf/10.1186/s12885-023-11347-7","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042485581","display_name":"Jungwook Roh","orcid":"https://orcid.org/0000-0003-0298-195X","observed_orcids":["https://orcid.org/0000-0003-0298-195X"]},"institutions":[{"id":"https://openalex.org/I141074810","display_name":"Korea National University of Education","ror":"https://ror.org/03c9fpk55","country_code":"KR","type":"education","lineage":["https://openalex.org/I141074810"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jungwook Roh","raw_affiliation_strings":["Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea","institution_ids":["https://openalex.org/I141074810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061281189","display_name":"B Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141074810","display_name":"Korea National University of Education","ror":"https://ror.org/03c9fpk55","country_code":"KR","type":"education","lineage":["https://openalex.org/I141074810"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Boseong Kim","raw_affiliation_strings":["Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea","institution_ids":["https://openalex.org/I141074810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035456006","display_name":"Mijung Im","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141074810","display_name":"Korea National University of Education","ror":"https://ror.org/03c9fpk55","country_code":"KR","type":"education","lineage":["https://openalex.org/I141074810"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Mijung Im","raw_affiliation_strings":["Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea","institution_ids":["https://openalex.org/I141074810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114079562","display_name":"Wonyi Jang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141074810","display_name":"Korea National University of Education","ror":"https://ror.org/03c9fpk55","country_code":"KR","type":"education","lineage":["https://openalex.org/I141074810"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Wonyi Jang","raw_affiliation_strings":["Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea","institution_ids":["https://openalex.org/I141074810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090130939","display_name":"Yeonsoo Chae","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141074810","display_name":"Korea National University of Education","ror":"https://ror.org/03c9fpk55","country_code":"KR","type":"education","lineage":["https://openalex.org/I141074810"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yeonsoo Chae","raw_affiliation_strings":["Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea","institution_ids":["https://openalex.org/I141074810"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102811506","display_name":"JiHoon Kang","orcid":"https://orcid.org/0000-0001-7231-5480","observed_orcids":["https://orcid.org/0000-0001-7231-5480"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4390039307","display_name":"Winship Cancer Institute","ror":"https://ror.org/02gars961","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666","https://openalex.org/I4390039307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JiHoon Kang","raw_affiliation_strings":["Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, 30322, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, 30322, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4390039307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005123608","display_name":"BuHyun Youn","orcid":"https://orcid.org/0000-0002-8010-519X","observed_orcids":["https://orcid.org/0000-0002-8010-519X"]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"BuHyun Youn","raw_affiliation_strings":["Department of Biological Sciences, Pusan National University, Busan, 46241, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Pusan National University, Busan, 46241, Republic of Korea","institution_ids":["https://openalex.org/I4921948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046356065","display_name":"Wanyeon Kim","orcid":"https://orcid.org/0000-0002-7611-5248","observed_orcids":["https://orcid.org/0000-0002-7611-5248"]},"institutions":[{"id":"https://openalex.org/I141074810","display_name":"Korea National University of Education","ror":"https://ror.org/03c9fpk55","country_code":"KR","type":"education","lineage":["https://openalex.org/I141074810"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Wanyeon Kim","raw_affiliation_strings":["Department of Biology Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea. wykim82@knue.ac.kr","Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea. wykim82@knue.ac.kr","Department of Biology Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea. wykim82@knue.ac.kr","institution_ids":["https://openalex.org/I141074810"]},{"raw_affiliation_string":"Department of Science Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea. wykim82@knue.ac.kr","institution_ids":["https://openalex.org/I141074810"]},{"raw_affiliation_string":"Department of Biology Education, Korea National University of Education, Cheongju-si, 28173, Chungbuk, Republic of Korea","institution_ids":["https://openalex.org/I141074810"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5046356065"],"corresponding_institution_ids":["https://openalex.org/I141074810"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":2.7361,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.92123555,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"23","issue":"1","first_page":"818","last_page":"818"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malat1","display_name":"MALAT1","score":0.9929999709129333},{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"long non-coding RNA","score":0.8510000109672546},{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":1.0},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.7649999856948853},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.9020000100135803},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.6330000162124634},{"id":"https://openalex.org/keywords/cell-invasion","display_name":"cell invasion","score":0.6330000162124634},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.7229999899864197},{"id":"https://openalex.org/keywords/pgam1","display_name":"phosphoglycerate mutase 1","score":0.7739999890327454},{"id":"https://openalex.org/keywords/sesn1","display_name":"SESN1","score":0.9890000224113464},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7850000262260437},{"id":"https://openalex.org/keywords/oncogenes","display_name":"oncogenes","score":0.5699999928474426},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.42800000309944153},{"id":"https://openalex.org/keywords/cell-survival","display_name":"cell survival","score":0.453000009059906},{"id":"https://openalex.org/keywords/patient-survival","display_name":"patient survival","score":0.4790000021457672}],"concepts":[{"id":"https://openalex.org/C2779134362","wikidata":"https://www.wikidata.org/wiki/Q18056223","display_name":"MALAT1","level":5,"score":0.8220136761665344},{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.7265443801879883},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.6647175550460815},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.6007688045501709},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5846107006072998},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.5579534769058228},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5404459238052368},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.4742554724216461},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4618925154209137},{"id":"https://openalex.org/C2780140570","wikidata":"https://www.wikidata.org/wiki/Q3545481","display_name":"Surgical oncology","level":2,"score":0.42945438623428345},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.42902401089668274},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.34379082918167114},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3155021667480469},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.29157131910324097},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28859472274780273},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.27685603499412537},{"id":"https://openalex.org/C62203573","wikidata":"https://www.wikidata.org/wiki/Q15087973","display_name":"Long non-coding RNA","level":4,"score":0.11102735996246338},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09438037872314453}],"mesh":[{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010736","descriptor_name":"Phosphoglycerate Mutase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12885-023-11347-7","doi":"https://doi.org/10.1186/s12885-023-11347-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12885-023-11347-7","pdf_url":"https://bmccancer.biomedcentral.com/counter/pdf/10.1186/s12885-023-11347-7","source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10476395","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10476395","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10476395/pdf/12885_2023_Article_11347.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"Text"},{"id":"pmid:37667226","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37667226","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC cancer","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:7e23dd491f284581a6fa655b89e58fdc","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7e23dd491f284581a6fa655b89e58fdc","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12885-023-11347-7","doi":"https://doi.org/10.1186/s12885-023-11347-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12885-023-11347-7","pdf_url":"https://bmccancer.biomedcentral.com/counter/pdf/10.1186/s12885-023-11347-7","source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2325532440","display_name":null,"funder_award_id":"2019R1C1C1009423","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G4244324037","display_name":null,"funder_award_id":"2022R1A6A3A13072277","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G6013886011","display_name":null,"funder_award_id":"2022R1F1A1064399","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"}],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"},{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386413629.pdf","grobid_xml":"https://content.openalex.org/works/W4386413629.grobid-xml"},"referenced_works_count":82,"referenced_works":["https://openalex.org/W801564649","https://openalex.org/W1966010275","https://openalex.org/W1975066282","https://openalex.org/W1986919130","https://openalex.org/W2012915718","https://openalex.org/W2062967876","https://openalex.org/W2070923004","https://openalex.org/W2079298347","https://openalex.org/W2081158948","https://openalex.org/W2102278945","https://openalex.org/W2103017472","https://openalex.org/W2104005232","https://openalex.org/W2104662981","https://openalex.org/W2136222002","https://openalex.org/W2158217645","https://openalex.org/W2159482845","https://openalex.org/W2204638621","https://openalex.org/W2275678839","https://openalex.org/W2322946267","https://openalex.org/W2510875395","https://openalex.org/W2517609385","https://openalex.org/W2744114848","https://openalex.org/W2748203030","https://openalex.org/W2759421472","https://openalex.org/W2769383666","https://openalex.org/W2784694452","https://openalex.org/W2803913659","https://openalex.org/W2805666238","https://openalex.org/W2806118255","https://openalex.org/W2808555564","https://openalex.org/W2887172059","https://openalex.org/W2887889028","https://openalex.org/W2889646458","https://openalex.org/W2892712216","https://openalex.org/W2897881262","https://openalex.org/W2903139824","https://openalex.org/W2907488202","https://openalex.org/W2951523021","https://openalex.org/W2954166030","https://openalex.org/W2954805572","https://openalex.org/W2960527099","https://openalex.org/W2963498830","https://openalex.org/W2969718750","https://openalex.org/W2989845311","https://openalex.org/W2994630788","https://openalex.org/W2997162920","https://openalex.org/W3021123576","https://openalex.org/W3033791775","https://openalex.org/W3080185518","https://openalex.org/W3080539582","https://openalex.org/W3091616850","https://openalex.org/W3109329045","https://openalex.org/W3118092689","https://openalex.org/W3118858701","https://openalex.org/W3129175901","https://openalex.org/W3135882325","https://openalex.org/W3176094949","https://openalex.org/W3179132402","https://openalex.org/W3194737367","https://openalex.org/W3195666297","https://openalex.org/W3204864663","https://openalex.org/W3206851139","https://openalex.org/W4200464648","https://openalex.org/W4210903306","https://openalex.org/W4220831425","https://openalex.org/W4223430732","https://openalex.org/W4226059287","https://openalex.org/W4232719563","https://openalex.org/W4286566105","https://openalex.org/W4294216483","https://openalex.org/W4294739385","https://openalex.org/W4296448340","https://openalex.org/W4307425304","https://openalex.org/W4308912895","https://openalex.org/W4310472593","https://openalex.org/W4312223298","https://openalex.org/W4320918966","https://openalex.org/W4322503161","https://openalex.org/W6757036487","https://openalex.org/W6778863408","https://openalex.org/W6814399200","https://openalex.org/W6849832982"],"related_works":["https://openalex.org/W3031365541","https://openalex.org/W6902032243","https://openalex.org/W6939768357","https://openalex.org/W6939790484","https://openalex.org/W3215352849","https://openalex.org/W1988633298","https://openalex.org/W7135074192","https://openalex.org/W2277315165","https://openalex.org/W3092797031","https://openalex.org/W2105774236"],"abstract_inverted_index":{"BACKGROUND:":[0],"Non-small":[1],"cell":[2,87,120,186,192,208,218,243,313],"lung":[3,12,36,185],"cancer":[4,13],"(NSCLC)":[5],"is":[6,25],"the":[7,59,72,79,92,137,189,202,253,258,300,326,363],"most":[8],"common":[9,249],"type":[10],"of":[11,35,63,81,83,97,113,139,222,260,289,328,354,366],"and":[14,32,45,61,89,125,146,157,170,188,212,232,282,318,321,335,347],"has":[15,39,51],"a":[16,55],"poor":[17],"prognosis.":[18],"Identifying":[19],"biomarkers":[20],"based":[21],"on":[22,247,362],"molecular":[23],"mechanisms":[24],"critical":[26],"for":[27,58,166],"early":[28],"diagnosis,":[29],"timely":[30],"treatment,":[31],"improved":[33],"prognosis":[34,62],"cancer.":[37,64],"MALAT1":[38,84,103,114,140,152,178,196,205,237,304,367],"been":[40,52],"reported":[41],"to":[42,70,78,90,136,295,340,344],"have":[43],"overexpressed":[44],"tumor-promoting":[46],"functions":[47,112],"in":[48,74,85,115,134,180,201,214,224,239,257,325,368],"NSCLC.":[49,369],"It":[50],"proposed":[53],"as":[54,307],"potential":[56],"biomarker":[57],"diagnosis":[60],"Therefore,":[65],"this":[66],"study":[67],"was":[68,141,198],"conducted":[69],"profile":[71],"changes":[73],"gene":[75,131,167,286,296],"expression":[76,82,104,132,168,179,197,287,297],"according":[77],"regulation":[80],"NSCLC":[86,116,191,203,217,225,242,312],"lines":[88,193],"investigate":[91],"correlation":[93],"through":[94],"bioinformatic":[95,322],"analysis":[96,169,176,221,246,298],"differentially":[98,147],"expressed":[99,148],"genes":[100,149],"(DEGs).":[101],"METHODS:":[102],"levels":[105,288],"were":[106,117,153,164,230,293,338],"measured":[107],"using":[108,252,299],"RT-qPCR.":[109],"The":[110,285],"biological":[111],"analyzed":[118,142],"by":[119,143,151,155,236],"counting,":[121],"colony":[122,316],"forming,":[123],"wound-healing,":[124],"Transwell":[126],"invasion":[127,213],"assays.":[128],"In":[129],"addition,":[130],"profiling":[133],"response":[135],"knockdown":[138,206,238],"transcriptome":[144],"sequencing,":[145],"regulated":[150],"performed":[154,251],"GO":[156],"KEGG":[158],"pathway":[159],"enrichment":[160],"analyses.":[161],"Bioinformatic":[162],"databases":[163],"used":[165],"overall":[171],"survival":[172,346],"analysis.":[173],"RESULTS:":[174],"Comparative":[175],"versus":[177],"MRC5":[181],"cells":[182,226],"(a":[183],"normal":[184],"line)":[187],"three":[190,216,241],"showed":[194,227],"that":[195,310,351],"significantly":[199],"higher":[200],"cells.":[204],"decreased":[207],"survival,":[209,314],"proliferation,":[210,315],"migration,":[211],"all":[215,240],"lines.":[219,244],"RNA-seq":[220,320],"DEGs":[223,229,234,250,292,357],"198":[228],"upregulated":[231],"266":[233],"downregulated":[235],"Survival":[245],"these":[248,290,355],"OncoLnc":[254],"database":[255],"resulted":[256,324],"selection":[259,327],"five":[261,329,356],"DEGs,":[262,330],"phosphoglycerate":[263,267],"mutase":[264,268],"1":[265,278],"(PGAM1),":[266],"4":[269],"(PGAM4),":[270],"nucleolar":[271],"protein":[272,277],"6":[273],"(NOL6),":[274],"nucleosome":[275],"assembly":[276],"like":[279],"5":[280],"(NAP1L5),":[281],"sestrin1":[283],"(SESN1).":[284],"selected":[291],"proved":[294],"TNMplot":[301],"database.":[302],"CONCLUSION:":[303],"might":[305],"function":[306],"an":[308],"oncogene":[309],"enhances":[311],"formation,":[317],"invasion.":[319],"analyses":[323],"PGAM1,":[331],"PGAM4,":[332],"NOL6,":[333],"NAP1L5,":[334],"SESN1,":[336],"which":[337],"found":[339],"be":[341],"closely":[342],"related":[343],"patient":[345],"tumorigenesis.":[348],"We":[349],"believe":[350],"further":[352],"investigation":[353],"will":[358],"provide":[359],"valuable":[360],"information":[361],"oncogenic":[364],"role":[365]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-09-05T00:00:00"}
