{"id":"https://openalex.org/W4386366338","doi":"https://doi.org/10.26538/tjnpr/v7i8.9","title":"Effect of Vitamin D3 on Hormonal and Histological Changes in Thyroid Gland Caused by Hyperprolactinemia of Male laboratory Rats (Rattus norvegicus)","display_name":"Effect of Vitamin D3 on Hormonal and Histological Changes in Thyroid Gland Caused by Hyperprolactinemia of Male laboratory Rats (Rattus norvegicus)","publication_year":2023,"publication_date":"2023-08-31","ids":{"openalex":"https://openalex.org/W4386366338","doi":"https://doi.org/10.26538/tjnpr/v7i8.9"},"language":"en","primary_location":{"id":"doi:10.26538/tjnpr/v7i8.9","doi":"https://doi.org/10.26538/tjnpr/v7i8.9","is_oa":true,"landing_page_url":"https://doi.org/10.26538/tjnpr/v7i8.9","pdf_url":"https://tjnpr.org/index.php/home/article/download/2402/3109","source":{"id":"https://openalex.org/S4210230334","display_name":"Tropical Journal of Natural Product Research","issn_l":"2616-0684","issn":["2616-0684","2616-0692"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-2","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310317826","host_organization_name":"University of Bern","host_organization_lineage":["https://openalex.org/P4310317826"],"host_organization_lineage_names":["University of Bern"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tropical Journal of Natural Product Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://tjnpr.org/index.php/home/article/download/2402/3109","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111033606","display_name":"Sumaya H. Sameer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I202735123","display_name":"Thi Qar University","ror":"https://ror.org/02ypa8k59","country_code":"IQ","type":"education","lineage":["https://openalex.org/I202735123"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Sumaya H. Sameer","raw_affiliation_strings":["Biology Department, College of Education for Pure Science, University of Thi-Qar, 64001, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, College of Education for Pure Science, University of Thi-Qar, 64001, Iraq","institution_ids":["https://openalex.org/I202735123"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015862466","display_name":"Hazar Shakir Saleh","orcid":"https://orcid.org/0000-0002-1029-1775","observed_orcids":["https://orcid.org/0000-0002-1029-1775"]},"institutions":[{"id":"https://openalex.org/I202735123","display_name":"Thi Qar University","ror":"https://ror.org/02ypa8k59","country_code":"IQ","type":"education","lineage":["https://openalex.org/I202735123"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Hazar S. Saleh","raw_affiliation_strings":["Biology Department, College of Education for Pure Science, University of Thi-Qar, 64001, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, College of Education for Pure Science, University of Thi-Qar, 64001, Iraq","institution_ids":["https://openalex.org/I202735123"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I202735123"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"8","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.02199999988079071,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-d3","display_name":"vitamin D3","score":0.9929999709129333},{"id":"https://openalex.org/keywords/hyperprolactinemia","display_name":"hyperprolactinemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/thyroid","display_name":"thyroid gland","score":0.9089999794960022},{"id":"https://openalex.org/keywords/triiodothyronine","display_name":"triiodothyronine","score":0.8600000143051147},{"id":"https://openalex.org/keywords/thyroxine","display_name":"thyroxine","score":1.0},{"id":"https://openalex.org/keywords/thyroid-stimulating-hormone","display_name":"thyroid-stimulating hormone","score":0.9399999976158142},{"id":"https://openalex.org/keywords/prolactin","display_name":"prolactin","score":0.8230000138282776},{"id":"https://openalex.org/keywords/thyroid-histology","display_name":"thyroid histology","score":0.7350000143051147},{"id":"https://openalex.org/keywords/thyroid-follicles","display_name":"thyroid follicles","score":0.925000011920929},{"id":"https://openalex.org/keywords/thyroid-follicular-cells","display_name":"thyroid follicular cells","score":0.8560000061988831},{"id":"https://openalex.org/keywords/thyroid-protection","display_name":"thyroid protection","score":0.5879999995231628}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8068255186080933},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.7967733144760132},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7918421626091003},{"id":"https://openalex.org/C2779064019","wikidata":"https://www.wikidata.org/wiki/Q66590068","display_name":"Prolactin","level":3,"score":0.7643880248069763},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.7461429834365845},{"id":"https://openalex.org/C2778288131","wikidata":"https://www.wikidata.org/wiki/Q327362","display_name":"Triiodothyronine","level":3,"score":0.6252070665359497},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.4912077784538269},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.47637245059013367},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4732157289981842},{"id":"https://openalex.org/C2777886399","wikidata":"https://www.wikidata.org/wiki/Q211544","display_name":"Thyroid-stimulating hormone","level":3,"score":0.4537912905216217},{"id":"https://openalex.org/C2780159080","wikidata":"https://www.wikidata.org/wiki/Q1400536","display_name":"Intraperitoneal injection","level":2,"score":0.4468470811843872}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.26538/tjnpr/v7i8.9","doi":"https://doi.org/10.26538/tjnpr/v7i8.9","is_oa":true,"landing_page_url":"https://doi.org/10.26538/tjnpr/v7i8.9","pdf_url":"https://tjnpr.org/index.php/home/article/download/2402/3109","source":{"id":"https://openalex.org/S4210230334","display_name":"Tropical Journal of Natural Product Research","issn_l":"2616-0684","issn":["2616-0684","2616-0692"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-2","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310317826","host_organization_name":"University of Bern","host_organization_lineage":["https://openalex.org/P4310317826"],"host_organization_lineage_names":["University of Bern"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tropical Journal of Natural Product Research","raw_type":"journal-article"},{"id":"pmh:oai:ojs.tjnpr.org:article/2402","doi":null,"is_oa":true,"landing_page_url":"https://www.tjnpr.org/index.php/home/article/view/2402","pdf_url":null,"source":{"id":"https://openalex.org/S4210230334","display_name":"Tropical Journal of Natural Product Research","issn_l":"2616-0684","issn":["2616-0684","2616-0692"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-2","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310317826","host_organization_name":"University of Bern","host_organization_lineage":["https://openalex.org/P4310317826"],"host_organization_lineage_names":["University of Bern"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Tropical Journal of Natural Product Research (TJNPR); Vol. 7 No. 8 (2023): Tropical Journal of Natural Product Research (TJNPR); 3633-3636","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.26538/tjnpr/v7i8.9","doi":"https://doi.org/10.26538/tjnpr/v7i8.9","is_oa":true,"landing_page_url":"https://doi.org/10.26538/tjnpr/v7i8.9","pdf_url":"https://tjnpr.org/index.php/home/article/download/2402/3109","source":{"id":"https://openalex.org/S4210230334","display_name":"Tropical Journal of Natural Product Research","issn_l":"2616-0684","issn":["2616-0684","2616-0692"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-2","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310317826","host_organization_name":"University of Bern","host_organization_lineage":["https://openalex.org/P4310317826"],"host_organization_lineage_names":["University of Bern"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tropical Journal of Natural Product Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320319858","display_name":"University of Thi-Qar","ror":"https://ror.org/02ypa8k59"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386366338.pdf","grobid_xml":"https://content.openalex.org/works/W4386366338.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1615702087","https://openalex.org/W2080057665","https://openalex.org/W2134929591","https://openalex.org/W2147692150","https://openalex.org/W2183572982","https://openalex.org/W2334511474","https://openalex.org/W2755710197","https://openalex.org/W2799562700","https://openalex.org/W2924194243","https://openalex.org/W3012940263","https://openalex.org/W3040214562","https://openalex.org/W3212362981","https://openalex.org/W4205477539","https://openalex.org/W4211246989","https://openalex.org/W4220668273","https://openalex.org/W4235868462","https://openalex.org/W4253418025","https://openalex.org/W4317885843"],"related_works":["https://openalex.org/W7046728119","https://openalex.org/W4399255403","https://openalex.org/W3042182221","https://openalex.org/W7141640492","https://openalex.org/W2038252514","https://openalex.org/W7114926353","https://openalex.org/W2092885656","https://openalex.org/W3165375810","https://openalex.org/W6892671714","https://openalex.org/W2012165082"],"abstract_inverted_index":{"Hyperprolactinemia":[0,170],"is":[1],"commonly":[2],"known":[3],"as":[4],"abnormal":[5],"levels":[6,144,154,236],"of":[7,44,96,132,174,176,180,213,239],"prolactin":[8,141],"hormone":[9,105,114],"in":[10,140,150,155,204],"the":[11,24,94,119,133,177,181,192,205],"blood":[12],"due":[13],"to":[14,20,191],"endocrine":[15],"disorder.":[16],"The":[17,49,59,77,130,216],"study":[18,134,217],"aimed":[19],"eliminate":[21],"hyperprolactinemia":[22,72,193],"affecting":[23],"thyroid":[25,120,178,214,227,243],"gland":[26,121,179,228],"by":[27,68,87,229],"treating":[28],"it":[29],"with":[30,161,166,184,251],"vitamin":[31,85,162,185,220],"D":[32,163,209],"supplements.":[33],"Eighteen":[34],"male":[35],"rats":[36,46,62,81],"Rattus":[37],"norvegicus":[38],"were":[39,63,116],"divided":[40],"into":[41],"three":[42],"groups":[43],"six":[45],"each":[47],":":[48],"first":[50],"group":[51,159,182,206],"received":[52,82],"normal":[53,253],"saline":[54],"for":[55,71,74,90,127],"42":[56],"days":[57],".":[58],"second":[60],"group,":[61,79],"given":[64,207],"5":[65],"mg/kg":[66,84],"metoclopramide":[67],"intraperitoneal":[69,88],"injection":[70,89],"induction":[73],"14":[75],"days.":[76,92],"third":[78],"hyperprolactinemic":[80],"2.5":[83],"D3":[86,186,221],"28":[91],"After":[93],"end":[95],"experimental":[97],")42":[98],"days(,":[99],"hormonal":[100],"parameters":[101],"(prolactin":[102],"hormone,":[103],"Triiodothyronine":[104],")T3(,":[106],"and":[107,118,125,142,145,152,211,233,237,242],"Thyroxine":[108],"hormone)":[109],"T4)":[110],",":[111],"Thyroid":[112,196],"stimulating":[113],")TSH(":[115],"measure,":[117],"was":[122],"removed,":[123],"processed":[124],"examine":[126],"histomorphological":[128],"changes.":[129],"result":[131],"revealed":[135],"a":[136,146,223],"significant":[137,147,188],"decrease":[138],"(P\u22640.01)":[139,149],"TSH":[143,234],"increase":[148],"T3":[151],"T4":[153],"Group":[156,167],"3":[157,210],")Hyperprolactinemia":[158],"treated":[160,183],"(":[164],"compared":[165,190],"2":[168],")":[169],"group(.":[171],"Histological":[172],"examination":[173],"sections":[175],"showed":[187],"restoration":[189,238],"rats,":[194],"throughout.":[195],"follicles":[197,244],"became":[198,245],"larger,":[199,246],"containing":[200,247],"dense":[201,248],"colloidal":[202,249],"material,":[203,250],"Vitaim":[208],"structures":[212],"follicles.":[215],"concluded":[218],"that":[219],"had":[222],"protective":[224],"effect":[225],"on":[226],"stabilizing":[230],"T3,":[231],"T4,":[232],"hormones":[235],"histological":[240],"architectures":[241],"presence":[252],"thyrocytes":[254],"remarkably.":[255]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-09-02T00:00:00"}