{"id":"https://openalex.org/W4386157381","doi":"https://doi.org/10.1016/j.neuroimage.2023.120350","title":"Hyperpolarized [2\u201313C]pyruvate MR molecular imaging with whole brain coverage","display_name":"Hyperpolarized [2\u201313C]pyruvate MR molecular imaging with whole brain coverage","publication_year":2023,"publication_date":"2023-08-25","ids":{"openalex":"https://openalex.org/W4386157381","doi":"https://doi.org/10.1016/j.neuroimage.2023.120350","pmid":"https://pubmed.ncbi.nlm.nih.gov/37634883","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10530049"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroimage.2023.120350","doi":"https://doi.org/10.1016/j.neuroimage.2023.120350","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2023.120350","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.neuroimage.2023.120350","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005262861","display_name":"Brian T. Chung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian T. Chung","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044152347","display_name":"Yaewon Kim","orcid":"https://orcid.org/0000-0003-1016-1572","observed_orcids":["https://orcid.org/0000-0003-1016-1572"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yaewon Kim","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA. Electronic address: yaewon.kim@ucsf.edu","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA"],"raw_orcid":"https://orcid.org/0000-0003-1016-1572","affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA. Electronic address: yaewon.kim@ucsf.edu","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048416186","display_name":"Jeremy W. Gordon","orcid":"https://orcid.org/0000-0003-2760-4886","observed_orcids":["https://orcid.org/0000-0003-2760-4886"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremy W. Gordon","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033383368","display_name":"Hsin\u2010Yu Chen","orcid":"https://orcid.org/0000-0002-2765-1685","observed_orcids":["https://orcid.org/0000-0002-2765-1685"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hsin-Yu Chen","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053437075","display_name":"Adam W. Autry","orcid":"https://orcid.org/0000-0002-7062-4965","observed_orcids":["https://orcid.org/0000-0002-7062-4965"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam W. Autry","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Philip M. Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip M. Lee","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108006937","display_name":"Jasmine Y. Hu","orcid":"https://orcid.org/0000-0002-7259-0332","observed_orcids":["https://orcid.org/0000-0002-7259-0332"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jasmine Y. Hu","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113333992","display_name":"Chou T. Tan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405272585","display_name":"MilliporeSigma (United States)","ror":"https://ror.org/04cyww122","country_code":"US","type":"company","lineage":["https://openalex.org/I4405272585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chou T. Tan","raw_affiliation_strings":["ISOTEC Stable Isotope Division, MilliporeSigma, Merck KGaA, Miamisburg, OH 45342, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ISOTEC Stable Isotope Division, MilliporeSigma, Merck KGaA, Miamisburg, OH 45342, USA","institution_ids":["https://openalex.org/I4405272585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010074609","display_name":"Chris Suszczynski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405272585","display_name":"MilliporeSigma (United States)","ror":"https://ror.org/04cyww122","country_code":"US","type":"company","lineage":["https://openalex.org/I4405272585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chris Suszczynski","raw_affiliation_strings":["ISOTEC Stable Isotope Division, MilliporeSigma, Merck KGaA, Miamisburg, OH 45342, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ISOTEC Stable Isotope Division, MilliporeSigma, Merck KGaA, Miamisburg, OH 45342, USA","institution_ids":["https://openalex.org/I4405272585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111908438","display_name":"Susan Marina Chang","orcid":"https://orcid.org/0000-0003-3521-364X","observed_orcids":["https://orcid.org/0000-0003-3521-364X"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan M. Chang","raw_affiliation_strings":["Department of Neurological Surgery, University of California, San Francisco, CA 94158, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051765330","display_name":"Javier E. Villanueva-Meyer","orcid":"https://orcid.org/0000-0002-5910-0757","observed_orcids":["https://orcid.org/0000-0002-5910-0757"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Javier E. Villanueva-Meyer","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047945584","display_name":"Robert Bok","orcid":"https://orcid.org/0000-0003-1737-9056","observed_orcids":["https://orcid.org/0000-0003-1737-9056"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Bok","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035862378","display_name":"Peder E. Z. Larson","orcid":"https://orcid.org/0000-0003-4183-3634","observed_orcids":["https://orcid.org/0000-0003-4183-3634"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peder E.Z. Larson","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030100878","display_name":"Duan Xu","orcid":"https://orcid.org/0000-0003-0550-4235","observed_orcids":["https://orcid.org/0000-0003-0550-4235"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Duan Xu","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039980454","display_name":"Yan Li","orcid":"https://orcid.org/0000-0002-1875-0788","observed_orcids":["https://orcid.org/0000-0002-1875-0788"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yan Li","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033011683","display_name":"Daniel B. Vigneron","orcid":"https://orcid.org/0000-0001-5795-8699","observed_orcids":["https://orcid.org/0000-0001-5795-8699"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel B. Vigneron","raw_affiliation_strings":["Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA; Department of Neurological Surgery, University of California, San Francisco, CA 94158, USA","Department of Neurological Surgery, University of California, San Francisco, CA 94158, USA","Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, 1700 Fourth Street, Byers Hall Suite 102, San Francisco, CA 94158, USA; UCSF - UC Berkeley Graduate Program in Bioengineering, University of California, USA; Department of Neurological Surgery, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Neurological Surgery, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"UCSF \u2013 UC Berkeley Graduate Program in Bioengineering, University of California, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5044152347"],"corresponding_institution_ids":["https://openalex.org/I180670191"],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":{"value":3450,"currency":"USD","value_usd":3450},"fwci":1.6483,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.81976212,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"280","issue":null,"first_page":"120350","last_page":"120350"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.7095000147819519,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.7095000147819519,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11809","display_name":"Advanced NMR Techniques and Applications","score":0.2809999883174896,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11993","display_name":"Atomic and Subatomic Physics Research","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperpolarized-13c-mri","display_name":"hyperpolarized 13C MRI","score":0.9750000238418579},{"id":"https://openalex.org/keywords/brain-energy-metabolism","display_name":"brain energy metabolism","score":0.8159999847412109},{"id":"https://openalex.org/keywords/pyruvate-to-lactate-conversion","display_name":"pyruvate to lactate conversion","score":0.8489999771118164},{"id":"https://openalex.org/keywords/lactate","display_name":"lactate","score":0.6129999756813049},{"id":"https://openalex.org/keywords/glutamate","display_name":"glutamate","score":0.9850000143051147},{"id":"https://openalex.org/keywords/glycolysis","display_name":"glycolysis","score":0.8220000267028809},{"id":"https://openalex.org/keywords/oxidative-metabolism","display_name":"oxidative metabolism","score":0.9679999947547913},{"id":"https://openalex.org/keywords/whole-brain-imaging","display_name":"whole-brain imaging","score":0.6539999842643738},{"id":"https://openalex.org/keywords/metabolic-ratio","display_name":"metabolic ratio","score":0.46700000762939453}],"concepts":[{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.560883641242981},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.554405927658081},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5042194128036499},{"id":"https://openalex.org/C20251656","wikidata":"https://www.wikidata.org/wiki/Q162643","display_name":"Glycolysis","level":3,"score":0.49965500831604004},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.4354633092880249},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.42299219965934753},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2337999939918518},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20346692204475403},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.18099117279052734},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.12021854519844055},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018698","descriptor_name":"Glutamic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019289","descriptor_name":"Pyruvic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019344","descriptor_name":"Lactic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057054","descriptor_name":"Molecular Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.neuroimage.2023.120350","doi":"https://doi.org/10.1016/j.neuroimage.2023.120350","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2023.120350","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},{"id":"pmid:37634883","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37634883","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10530049","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10530049","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10530049/pdf/nihms-1931960.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Neuroimage","raw_type":"Text"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt5g3685q6","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/5g3685q6","pdf_url":"https://escholarship.org/content/qt5g3685q6/qt5g3685q6.pdf","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NeuroImage, vol 280","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:80b16af2de2f411fa0d9596665bfcda9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/80b16af2de2f411fa0d9596665bfcda9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NeuroImage, Vol 280, Iss , Pp 120350- (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.neuroimage.2023.120350","doi":"https://doi.org/10.1016/j.neuroimage.2023.120350","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2023.120350","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4964822892","display_name":"Development and Translation of Hyperpolarized C-13 Prostate Cancer MRI Methods","funder_award_id":"U01EB026412","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G5800834670","display_name":null,"funder_award_id":"P41EB0135898","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000862259","display_name":"Multimodality Neuroimaging Evaluation of Cognitive Functioning in Lower Grade Astrocytoma","funder_award_id":"R01CA273028","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000879606","display_name":"Quantitative Steady-State and Dynamic Metabolic MRI for Evaluating Patients with Glioma","funder_award_id":"R01CA262630","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000907380","display_name":"Hyperpolarized MRI Technology Resource Center","funder_award_id":"P41EB013598","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G9000912909","display_name":"Imaging and Genomic Signatures of Brain Tumor Heterogeneity and Evolution to Optimize Patient Management","funder_award_id":"P01CA118816","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332622","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1480324889","https://openalex.org/W1504651055","https://openalex.org/W1597040891","https://openalex.org/W1975107578","https://openalex.org/W2002190301","https://openalex.org/W2009190178","https://openalex.org/W2046654159","https://openalex.org/W2059900570","https://openalex.org/W2062657498","https://openalex.org/W2078236205","https://openalex.org/W2091723288","https://openalex.org/W2117950076","https://openalex.org/W2133665775","https://openalex.org/W2136573752","https://openalex.org/W2148726987","https://openalex.org/W2158164148","https://openalex.org/W2181312894","https://openalex.org/W2520679741","https://openalex.org/W2739560120","https://openalex.org/W2766869714","https://openalex.org/W2783916060","https://openalex.org/W2795504602","https://openalex.org/W2804495644","https://openalex.org/W2892266580","https://openalex.org/W2901018275","https://openalex.org/W2910792831","https://openalex.org/W2913635393","https://openalex.org/W2919705773","https://openalex.org/W2928537285","https://openalex.org/W2944352627","https://openalex.org/W2955499001","https://openalex.org/W2965597381","https://openalex.org/W2975630107","https://openalex.org/W2977177663","https://openalex.org/W2979914870","https://openalex.org/W3002623448","https://openalex.org/W3037768000","https://openalex.org/W3044694328","https://openalex.org/W3093231122","https://openalex.org/W3106655399","https://openalex.org/W3109313262","https://openalex.org/W3176975808","https://openalex.org/W3177222955","https://openalex.org/W3189983597","https://openalex.org/W3193391019","https://openalex.org/W4229014319","https://openalex.org/W4281702409","https://openalex.org/W4281743763","https://openalex.org/W4292324229","https://openalex.org/W6797647773"],"related_works":["https://openalex.org/W2910792831","https://openalex.org/W7058059412","https://openalex.org/W4414194371","https://openalex.org/W2979914870","https://openalex.org/W2997497393","https://openalex.org/W3206939938","https://openalex.org/W6887860028","https://openalex.org/W2125944083","https://openalex.org/W4414233121","https://openalex.org/W4283590931"],"abstract_inverted_index":{"Hyperpolarized":[0],"(HP)":[1],"13C":[2],"Magnetic":[3],"Resonance":[4],"Imaging":[5],"(MRI)":[6],"was":[7,38],"applied":[8],"for":[9],"the":[10,17,24],"first":[11],"time":[12],"to":[13,27,67,96],"image":[14],"and":[15,19,41,71,76,80,84,91,100],"quantify":[16],"uptake":[18],"metabolism":[20,102],"of":[21,74,88],"[2-13C]pyruvate":[22,37,75],"in":[23,43,53,103],"human":[25,46],"brain":[26,51],"provide":[28],"new":[29],"metabolic":[30],"information":[31],"on":[32],"cerebral":[33],"energy":[34],"metabolism.":[35],"HP":[36],"injected":[39],"intravenously":[40],"imaged":[42],"5":[44],"healthy":[45],"volunteer":[47],"exams":[48],"with":[49],"whole":[50],"coverage":[52],"a":[54,58,104],"1-minute":[55],"acquisition":[56],"using":[57],"specialized":[59],"spectral-spatial":[60],"multi-slice":[61],"echoplanar":[62],"imaging":[63],"(EPI)":[64],"pulse":[65],"sequence":[66],"acquire":[68],"13C-labeled":[69],"volumetric":[70],"dynamic":[72],"images":[73],"downstream":[77],"metabolites":[78],"[5-13C]glutamate":[79],"[2-13C]lactate.":[81],"Metabolic":[82],"ratios":[83],"apparent":[85],"conversion":[86],"rates":[87],"pyruvate-to-lactate":[89],"(kPL)":[90],"pyruvate-to-glutamate":[92],"(kPG)":[93],"were":[94],"quantified":[95],"investigate":[97],"simultaneously":[98],"glycolytic":[99],"oxidative":[101],"single":[105],"injection.":[106]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-08-26T00:00:00"}