{"id":"https://openalex.org/W4386089605","doi":"https://doi.org/10.1177/00031348231198108","title":"The Role of MRI in Assessing Residual Breast Cancer After Neoadjuvant Chemotherapy","display_name":"The Role of MRI in Assessing Residual Breast Cancer After Neoadjuvant Chemotherapy","publication_year":2023,"publication_date":"2023-08-23","ids":{"openalex":"https://openalex.org/W4386089605","doi":"https://doi.org/10.1177/00031348231198108","pmid":"https://pubmed.ncbi.nlm.nih.gov/37611928"},"language":"en","primary_location":{"id":"doi:10.1177/00031348231198108","doi":"https://doi.org/10.1177/00031348231198108","is_oa":false,"landing_page_url":"https://doi.org/10.1177/00031348231198108","pdf_url":null,"source":{"id":"https://openalex.org/S113474406","display_name":"The American Surgeon","issn_l":"0003-1348","issn":["0003-1348","1555-9823"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Surgeon\u2122","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027956292","display_name":"Emad Mofid Nassif Rezkallah","orcid":"https://orcid.org/0000-0002-1195-6652","observed_orcids":["https://orcid.org/0000-0002-1195-6652"]},"institutions":[{"id":"https://openalex.org/I2801184099","display_name":"James Cook University Hospital","ror":"https://ror.org/02vqh3346","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801184099","https://openalex.org/I286970279"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Emad Rezkallah","raw_affiliation_strings":["General Surgery Department, James Cook University Hospital, Middlesbrough, UK"],"raw_orcid":"https://orcid.org/0000-0002-1195-6652","affiliations":[{"raw_affiliation_string":"General Surgery Department, James Cook University Hospital, Middlesbrough, UK","institution_ids":["https://openalex.org/I2801184099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084240069","display_name":"Kamel Mekhaeil","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801184099","display_name":"James Cook University Hospital","ror":"https://ror.org/02vqh3346","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801184099","https://openalex.org/I286970279"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kamel Mekhaeil","raw_affiliation_strings":["Vascular Department, James Cook University Hospital, Middlesbrough, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vascular Department, James Cook University Hospital, Middlesbrough, UK","institution_ids":["https://openalex.org/I2801184099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064096672","display_name":"Su Min Min Tin","orcid":"https://orcid.org/0000-0003-0030-4947","observed_orcids":["https://orcid.org/0000-0003-0030-4947"]},"institutions":[{"id":"https://openalex.org/I2801184099","display_name":"James Cook University Hospital","ror":"https://ror.org/02vqh3346","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801184099","https://openalex.org/I286970279"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Su Min Min Tin","raw_affiliation_strings":["General Surgery Department, James Cook University Hospital, Middlesbrough, UK"],"raw_orcid":"https://orcid.org/0000-0003-0030-4947","affiliations":[{"raw_affiliation_string":"General Surgery Department, James Cook University Hospital, Middlesbrough, UK","institution_ids":["https://openalex.org/I2801184099"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046279557","display_name":"Ragai Sobhi Hanna","orcid":"https://orcid.org/0000-0001-8844-5853","observed_orcids":["https://orcid.org/0000-0001-8844-5853"]},"institutions":[{"id":"https://openalex.org/I91041137","display_name":"Assiut University","ror":"https://ror.org/01jaj8n65","country_code":"EG","type":"education","lineage":["https://openalex.org/I91041137"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Ragai Sobhy Hanna","raw_affiliation_strings":["Associate Professor of General Surgery, Assiut University, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Associate Professor of General Surgery, Assiut University, Egypt","institution_ids":["https://openalex.org/I91041137"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5027956292"],"corresponding_institution_ids":["https://openalex.org/I2801184099"],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":0.4044,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.50455019,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"90","issue":"2","first_page":"238","last_page":"244"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9570000171661377},{"id":"https://openalex.org/keywords/neoadjuvant-chemotherapy","display_name":"neoadjuvant chemotherapy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/residual-tumor","display_name":"residual tumor","score":0.6570000052452087},{"id":"https://openalex.org/keywords/post-treatment-mri","display_name":"post-treatment MRI","score":0.6460000276565552},{"id":"https://openalex.org/keywords/residual-disease-assessment","display_name":"residual disease assessment","score":0.6990000009536743},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.7350000143051147},{"id":"https://openalex.org/keywords/tumor-size-measurement","display_name":"tumor size measurement","score":0.5580000281333923},{"id":"https://openalex.org/keywords/histopathological-correlation","display_name":"histopathological correlation","score":0.5529999732971191},{"id":"https://openalex.org/keywords/treatment-decision-making","display_name":"treatment decision-making","score":0.6570000052452087}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8402525186538696},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.797637939453125},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.7450630068778992},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.6617361307144165},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5754624009132385},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5254570245742798},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.4964361786842346},{"id":"https://openalex.org/C2778292576","wikidata":"https://www.wikidata.org/wiki/Q6991934","display_name":"Neoadjuvant therapy","level":4,"score":0.4718860387802124},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3308866024017334},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3257957696914673}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001940","descriptor_name":"Breast","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017024","descriptor_name":"Chemotherapy, Adjuvant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018365","descriptor_name":"Neoplasm, Residual","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D018365","descriptor_name":"Neoplasm, Residual","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D020360","descriptor_name":"Neoadjuvant Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1177/00031348231198108","doi":"https://doi.org/10.1177/00031348231198108","is_oa":false,"landing_page_url":"https://doi.org/10.1177/00031348231198108","pdf_url":null,"source":{"id":"https://openalex.org/S113474406","display_name":"The American Surgeon","issn_l":"0003-1348","issn":["0003-1348","1555-9823"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Surgeon\u2122","raw_type":"journal-article"},{"id":"pmid:37611928","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37611928","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American surgeon","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1955397179","https://openalex.org/W1964538931","https://openalex.org/W1990185598","https://openalex.org/W2003555899","https://openalex.org/W2008536759","https://openalex.org/W2019271448","https://openalex.org/W2026718793","https://openalex.org/W2026981776","https://openalex.org/W2028492986","https://openalex.org/W2033387501","https://openalex.org/W2042809940","https://openalex.org/W2050555289","https://openalex.org/W2053074390","https://openalex.org/W2075894019","https://openalex.org/W2075911794","https://openalex.org/W2088835024","https://openalex.org/W2090595175","https://openalex.org/W2117775530","https://openalex.org/W2124653673","https://openalex.org/W2125449863","https://openalex.org/W2134269295","https://openalex.org/W2147415463","https://openalex.org/W2158614431","https://openalex.org/W2160408484","https://openalex.org/W2164774797","https://openalex.org/W2168441082","https://openalex.org/W2381569410","https://openalex.org/W2587342572","https://openalex.org/W2601141570","https://openalex.org/W2607796523","https://openalex.org/W3182849187","https://openalex.org/W3197299662","https://openalex.org/W4301159569"],"related_works":["https://openalex.org/W2260591700","https://openalex.org/W7220032112","https://openalex.org/W2055131397","https://openalex.org/W2057016707","https://openalex.org/W3092621965","https://openalex.org/W2019271448","https://openalex.org/W3184898418","https://openalex.org/W3168418507","https://openalex.org/W2979603052","https://openalex.org/W7055380085"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Breast":[1],"cancer":[2,24,95,228],"is":[3,25,49,214],"the":[4,11,20,30,37,46,52,55,60,72,77,120,131,143,147,173,179,220,248],"most":[5],"common":[6],"malignancy":[7],"among":[8],"women":[9],"in":[10,19,58,68,96,107,160,226],"world.":[12],"The":[13,27,43,163,199],"role":[14,44,53],"of":[15,22,45,54,192,232,250],"neoadjuvant":[16],"chemotherapy":[17],"(NAC)":[18],"management":[21,31,249],"breast":[23,94,227],"increasing.":[26],"decision":[28,69,246],"about":[29],"after":[32,63,224],"NAC":[33,101,225],"depends":[34],"mainly":[35],"on":[36,176],"tumor":[38,122,174,222],"response":[39],"to":[40,50,118,129,141,218],"NAC.":[41],"OBJECTIVES:":[42],"current":[47],"study":[48,109],"evaluate":[51],"MRI":[56,149,185],"scan":[57,117],"assessing":[59],"residual":[61,121,221],"disease":[62,223],"NAC,":[64],"which":[65,239],"would":[66],"help":[67],"making":[70,244],"regarding":[71,247],"best":[73],"treatment":[74],"plan":[75],"for":[76,87,181],"patient.":[78],"PATIENTS":[79],"AND":[80],"METHODS:":[81],"We":[82,171,183],"did":[83],"this":[84],"retrospective":[85],"review":[86],"all":[88],"patients":[89,106,157],"who":[90],"were":[91,158],"diagnosed":[92],"with":[93],"our":[97,108,161],"center":[98],"and":[99,134,151,189,196,234],"had":[100,110],"over":[102],"four":[103],"years.":[104,170],"All":[105],"a":[111,215,245],"post-NAC":[112,148],"magnetic":[113],"resonance":[114,212],"imaging":[115,213],"(MRI)":[116],"assess":[119,219],"size.":[123,153],"A":[124],"2\u00d72":[125],"table":[126],"was":[127,139,166,202],"used":[128,140],"calculate":[130],"diagnostic":[132],"accuracy,":[133],"SPSS":[135],"software":[136],"version":[137],"25":[138],"get":[142],"correlation":[144,200],"coefficients":[145],"between":[146],"measurements":[150],"pathological":[152],"RESULTS:":[154],"28":[155],"female":[156],"included":[159],"study.":[162],"average":[164],"age":[165],"45.25":[167],"\u00b1":[168],"10":[169],"utilized":[172],"size":[175],"histology":[177],"as":[178],"standard":[180],"comparison.":[182],"calculated":[184],"sensitivity,":[186],"specificity,":[187],"PPV,":[188],"NPV":[190],"rates":[191],"90.9%,":[193],"100%,":[194,195],"94.4%,":[197],"respectively.":[198],"coefficient":[201],"strong":[203],"(r":[204],"=":[205,208],"0.859,":[206],"P":[207],"0.01).":[209],"CONCLUSION:":[210],"Magnetic":[211],"good":[216],"test":[217],"patients.":[229],"However,":[230],"cases":[231],"under-":[233],"overestimation":[235],"are":[236],"still":[237],"seen,":[238],"require":[240],"more":[241],"caution":[242],"when":[243],"such":[251],"cases.":[252]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-08-24T00:00:00"}
