{"id":"https://openalex.org/W4386043760","doi":"https://doi.org/10.3390/nu15163659","title":"Lactiplantibacillus pentoses CCFM1227 Produces Desaminotyrosine to Protect against Influenza Virus H1N1 Infection through the Type I Interferon in Mice","display_name":"Lactiplantibacillus pentoses CCFM1227 Produces Desaminotyrosine to Protect against Influenza Virus H1N1 Infection through the Type I Interferon in Mice","publication_year":2023,"publication_date":"2023-08-21","ids":{"openalex":"https://openalex.org/W4386043760","doi":"https://doi.org/10.3390/nu15163659","pmid":"https://pubmed.ncbi.nlm.nih.gov/37630849","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10458433"},"language":"en","primary_location":{"id":"doi:10.3390/nu15163659","doi":"https://doi.org/10.3390/nu15163659","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu15163659","pdf_url":"https://www.mdpi.com/2072-6643/15/16/3659/pdf?version=1692595892","source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2072-6643/15/16/3659/pdf?version=1692595892","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100609687","display_name":"Qianwen Wang","orcid":"https://orcid.org/0000-0003-3553-1162","observed_orcids":["https://orcid.org/0000-0003-3553-1162"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]},{"id":"https://openalex.org/I4210152154","display_name":"State Key Laboratory of Food Science and Technology","ror":"https://ror.org/04zgj7914","country_code":"CN","type":"facility","lineage":["https://openalex.org/I111599522","https://openalex.org/I141649914","https://openalex.org/I4210152154"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianwen Wang","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522","https://openalex.org/I4210152154"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069584467","display_name":"Zhifeng Fang","orcid":"https://orcid.org/0000-0001-8077-4310","observed_orcids":["https://orcid.org/0000-0001-8077-4310"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]},{"id":"https://openalex.org/I4210152154","display_name":"State Key Laboratory of Food Science and Technology","ror":"https://ror.org/04zgj7914","country_code":"CN","type":"facility","lineage":["https://openalex.org/I111599522","https://openalex.org/I141649914","https://openalex.org/I4210152154"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhifeng Fang","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522","https://openalex.org/I4210152154"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007973458","display_name":"Yue Xiao","orcid":"https://orcid.org/0000-0001-9443-5803","observed_orcids":["https://orcid.org/0000-0001-9443-5803"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]},{"id":"https://openalex.org/I4210152154","display_name":"State Key Laboratory of Food Science and Technology","ror":"https://ror.org/04zgj7914","country_code":"CN","type":"facility","lineage":["https://openalex.org/I111599522","https://openalex.org/I141649914","https://openalex.org/I4210152154"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Xiao","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522","https://openalex.org/I4210152154"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007271117","display_name":"Hongchao Wang","orcid":"https://orcid.org/0000-0001-7148-7555","observed_orcids":["https://orcid.org/0000-0001-7148-7555"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]},{"id":"https://openalex.org/I4210152154","display_name":"State Key Laboratory of Food Science and Technology","ror":"https://ror.org/04zgj7914","country_code":"CN","type":"facility","lineage":["https://openalex.org/I111599522","https://openalex.org/I141649914","https://openalex.org/I4210152154"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hongchao Wang","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China"],"raw_orcid":"https://orcid.org/0000-0001-7148-7555","affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522","https://openalex.org/I4210152154"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019677279","display_name":"Pinghu Zhang","orcid":"https://orcid.org/0000-0002-7600-4740","observed_orcids":["https://orcid.org/0000-0002-7600-4740"]},"institutions":[{"id":"https://openalex.org/I78978612","display_name":"Yangzhou University","ror":"https://ror.org/03tqb8s11","country_code":"CN","type":"education","lineage":["https://openalex.org/I78978612"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pinghu Zhang","raw_affiliation_strings":["Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225009, China","Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College, Yangzhou University, Yangzhou 225009, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225009, China","institution_ids":["https://openalex.org/I78978612"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College, Yangzhou University, Yangzhou 225009, China","institution_ids":["https://openalex.org/I78978612"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086672489","display_name":"Wenwei Lu","orcid":"https://orcid.org/0000-0002-8636-9815","observed_orcids":["https://orcid.org/0000-0002-8636-9815"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]},{"id":"https://openalex.org/I4210152154","display_name":"State Key Laboratory of Food Science and Technology","ror":"https://ror.org/04zgj7914","country_code":"CN","type":"facility","lineage":["https://openalex.org/I111599522","https://openalex.org/I141649914","https://openalex.org/I4210152154"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenwei Lu","raw_affiliation_strings":["National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China","School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522","https://openalex.org/I4210152154"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113990871","display_name":"Hao Zhang","orcid":"https://orcid.org/0000-0002-9192-4684","observed_orcids":["https://orcid.org/0000-0002-9192-4684","https://orcid.org/0000-0003-3741-7494","https://orcid.org/0000-0002-3322-3070","https://orcid.org/0000-0002-5046-9785","https://orcid.org/0000-0003-0916-8371","https://orcid.org/0000-0002-1656-0091"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]},{"id":"https://openalex.org/I4210152154","display_name":"State Key Laboratory of Food Science and Technology","ror":"https://ror.org/04zgj7914","country_code":"CN","type":"facility","lineage":["https://openalex.org/I111599522","https://openalex.org/I141649914","https://openalex.org/I4210152154"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Zhang","raw_affiliation_strings":["National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China","School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China","Yangzhou Institute of Food Biotechnology, Jiangnan University, Yangzhou 225004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China","institution_ids":["https://openalex.org/I111599522","https://openalex.org/I4210152154"]},{"raw_affiliation_string":"Yangzhou Institute of Food Biotechnology, Jiangnan University, Yangzhou 225004, China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"last","author":{"id":null,"display_name":"Xiuwen Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153519","display_name":"First Affiliated Hospital of Soochow University","ror":"https://ror.org/051jg5p78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153519"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiuwen Zhou","raw_affiliation_strings":["Institute for Fetology, The First Affiliated Hospital of Soochow University, Suzhou 215021, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Fetology, The First Affiliated Hospital of Soochow University, Suzhou 215021, China","institution_ids":["https://openalex.org/I4210153519"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5007271117"],"corresponding_institution_ids":["https://openalex.org/I111599522","https://openalex.org/I4210152154","https://openalex.org/I4210153519"],"apc_list":{"value":2600,"currency":"CHF","value_usd":2892},"apc_paid":{"value":2600,"currency":"CHF","value_usd":2892},"fwci":2.1598,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.85622991,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"15","issue":"16","first_page":"3659","last_page":"3659"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/h1n1-influenza","display_name":"H1N1 influenza","score":0.9190000295639038},{"id":"https://openalex.org/keywords/type-i-interferon","display_name":"type I interferon","score":0.9760000109672546},{"id":"https://openalex.org/keywords/interferon-beta","display_name":"interferon-beta","score":0.878000020980835},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.8769999742507935},{"id":"https://openalex.org/keywords/mhc-class-i-genes","display_name":"MHC class I genes","score":0.7480000257492065},{"id":"https://openalex.org/keywords/lung-immunopathology","display_name":"lung immunopathology","score":0.8519999980926514},{"id":"https://openalex.org/keywords/viral-replication","display_name":"viral replication","score":0.5220000147819519}],"concepts":[{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.7704192399978638},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6738492846488953},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6250403523445129},{"id":"https://openalex.org/C2777546802","wikidata":"https://www.wikidata.org/wiki/Q834390","display_name":"Influenza A virus","level":3,"score":0.5966642498970032},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.5931683778762817},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5795563459396362},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.5309550166130066},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5054905414581299},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4129018485546112},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09535643458366394},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003141","descriptor_name":"Communicable Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007251","descriptor_name":"Influenza, Human","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D007370","descriptor_name":"Interferon Type I","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009976","descriptor_name":"Orthomyxoviridae Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009976","descriptor_name":"Orthomyxoviridae Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D010666","descriptor_name":"Phenylpropionates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053118","descriptor_name":"Influenza A Virus, H1N1 Subtype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.3390/nu15163659","doi":"https://doi.org/10.3390/nu15163659","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu15163659","pdf_url":"https://www.mdpi.com/2072-6643/15/16/3659/pdf?version=1692595892","source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10458433","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10458433","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10458433/pdf/nutrients-15-03659.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"Text"},{"id":"pmid:37630849","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37630849","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/nu15163659","doi":"https://doi.org/10.3390/nu15163659","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu15163659","pdf_url":"https://www.mdpi.com/2072-6643/15/16/3659/pdf?version=1692595892","source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7699999809265137,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1349572817","display_name":null,"funder_award_id":"31820103010","funder_id":"https://openalex.org/F4320336359","funder_display_name":"Collaborative Innovationcenter of Food Safety and Quality Control in Jiangsu Province"},{"id":"https://openalex.org/G2724276747","display_name":null,"funder_award_id":"SKJY2021068","funder_id":"https://openalex.org/F4320327912","funder_display_name":"Higher Education Discipline Innovation Project"},{"id":"https://openalex.org/G272864900","display_name":null,"funder_award_id":"31820103010","funder_id":"https://openalex.org/F4320316879","funder_display_name":"Natural Science Foundation of Suzhou City"},{"id":"https://openalex.org/G2874422979","display_name":null,"funder_award_id":"31820103010","funder_id":"https://openalex.org/F4320327912","funder_display_name":"Higher Education Discipline Innovation Project"},{"id":"https://openalex.org/G351554112","display_name":null,"funder_award_id":"SKJY2021068","funder_id":"https://openalex.org/F4320316879","funder_display_name":"Natural Science Foundation of Suzhou City"},{"id":"https://openalex.org/G4153755248","display_name":null,"funder_award_id":"SKJY2021068","funder_id":"https://openalex.org/F4320336359","funder_display_name":"Collaborative Innovationcenter of Food Safety and Quality Control in Jiangsu Province"},{"id":"https://openalex.org/G581096895","display_name":null,"funder_award_id":"SKJY2021068","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6333632204","display_name":null,"funder_award_id":"BP0719028","funder_id":"https://openalex.org/F4320336359","funder_display_name":"Collaborative Innovationcenter of Food Safety and Quality Control in Jiangsu Province"},{"id":"https://openalex.org/G7016426994","display_name":null,"funder_award_id":"BP0719028","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7506394322","display_name":null,"funder_award_id":"31820103010","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7761252358","display_name":null,"funder_award_id":"BP0719028","funder_id":"https://openalex.org/F4320316879","funder_display_name":"Natural Science Foundation of Suzhou City"},{"id":"https://openalex.org/G8351445526","display_name":null,"funder_award_id":"BP0719028","funder_id":"https://openalex.org/F4320327912","funder_display_name":"Higher Education Discipline Innovation Project"}],"funders":[{"id":"https://openalex.org/F4320316879","display_name":"Natural Science Foundation of Suzhou City","ror":null},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320324130","display_name":"Yangzhou University","ror":"https://ror.org/03tqb8s11"},{"id":"https://openalex.org/F4320327912","display_name":"Higher Education Discipline Innovation Project","ror":null},{"id":"https://openalex.org/F4320336359","display_name":"Collaborative Innovationcenter of Food Safety and Quality Control in Jiangsu Province","ror":"https://ror.org/01cvdks57"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4386043760.pdf","grobid_xml":"https://content.openalex.org/works/W4386043760.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W1508121266","https://openalex.org/W1985056697","https://openalex.org/W1992088744","https://openalex.org/W1998653357","https://openalex.org/W2022386478","https://openalex.org/W2031913105","https://openalex.org/W2072383590","https://openalex.org/W2088411176","https://openalex.org/W2109593713","https://openalex.org/W2126623340","https://openalex.org/W2557506312","https://openalex.org/W2607318868","https://openalex.org/W2743370588","https://openalex.org/W2775569101","https://openalex.org/W2796356314","https://openalex.org/W2802205848","https://openalex.org/W2806126291","https://openalex.org/W2936757566","https://openalex.org/W2936842947","https://openalex.org/W2944331050","https://openalex.org/W2947503157","https://openalex.org/W2952225287","https://openalex.org/W2962705835","https://openalex.org/W2971449941","https://openalex.org/W2972665961","https://openalex.org/W2973228172","https://openalex.org/W2980654983","https://openalex.org/W2996636801","https://openalex.org/W3013833922","https://openalex.org/W3017488767","https://openalex.org/W3042928905","https://openalex.org/W3043244612","https://openalex.org/W3092522893","https://openalex.org/W3120247780","https://openalex.org/W3128740483","https://openalex.org/W3129517261","https://openalex.org/W3164223157","https://openalex.org/W3166874270","https://openalex.org/W3182350146","https://openalex.org/W4210622611","https://openalex.org/W4214851298","https://openalex.org/W4230967288","https://openalex.org/W4283011712","https://openalex.org/W4285587737","https://openalex.org/W4288748803"],"related_works":["https://openalex.org/W2743370588","https://openalex.org/W4283752192","https://openalex.org/W4385693416","https://openalex.org/W1992144919","https://openalex.org/W2051988792","https://openalex.org/W1980566640","https://openalex.org/W4291383516","https://openalex.org/W2009917983","https://openalex.org/W2744613530","https://openalex.org/W4388930759"],"abstract_inverted_index":{"Microbiota-derived":[0],"desaminotyrosine":[1],"(DAT)":[2],"protects":[3],"the":[4,10,24,59,72,81,86,102,126,130,142,145,149,152,160,168,184],"host":[5],"from":[6,109],"influenza":[7,110],"by":[8,69,92,180],"modulating":[9],"type":[11],"I":[12],"interferon":[13],"(IFN)":[14],"response.":[15,171],"The":[16,55,78,132],"aim":[17],"of":[18,27,58,144,162],"this":[19,187],"study":[20],"was":[21,122],"to":[22,42,51,148,154],"investigate":[23],"antivirus":[25],"effects":[26,179],"a":[28,190],"DAT-producing":[29],"bacteria":[30],"strain.":[31],"A":[32],"comparative":[33],"genomics":[34],"analysis":[35],"and":[36,47,89,107,115,151,186],"UHPLC":[37],"Q-Exactive":[38],"MS":[39],"were":[40,62],"used":[41],"search":[43],"for":[44,193],"potential":[45,191],"strains":[46],"confirm":[48],"their":[49],"ability":[50],"produce":[52],"DAT,":[53],"respectively.":[54],"anti-influenza":[56],"functions":[57],"DAT":[60,91,103,121,182],"producer":[61],"evaluated":[63],"using":[64],"an":[65],"antibiotic-treated":[66],"mouse":[67],"model":[68],"orally":[70],"administering":[71],"specific":[73],"strain":[74],"before":[75],"viral":[76,113],"infection.":[77],"results":[79,134],"showed":[80,135],"Lactiplantibacillus":[82],"pentosus":[83,98,175],"CCFM1227":[84,99,137,157,176],"contained":[85],"phy":[87],"gene":[88,139],"produced":[90],"degrading":[93],"phloretin.":[94],"In":[95,172],"vivo,":[96],"L.":[97,174],"re-inoculation":[100],"increased":[101],"level":[104,128],"in":[105,129,141,183],"feces,":[106],"protected":[108],"through":[111],"inhibiting":[112],"replication":[114],"alleviating":[116],"lung":[117],"immunopathology.":[118],"Furthermore,":[119],"CCFM1227-derived":[120],"positively":[123],"correlated":[124],"with":[125],"IFN-\u03b2":[127],"lung.":[131],"transcriptome":[133],"that":[136],"activated":[138],"expression":[140,161],"context":[143],"defense":[146],"response":[147,153],"virus,":[150],"interferon-beta.":[155],"Moreover,":[156],"treatment":[158],"upregulated":[159],"MHC-I":[163],"family":[164],"genes,":[165],"which":[166],"regulate":[167],"adaptive":[169],"immune":[170],"conclusion,":[173],"exerted":[177],"antiviral":[178,196],"producing":[181],"gut,":[185],"may":[188],"provide":[189],"solution":[192],"creating":[194],"effective":[195],"probiotics.":[197]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-08-22T00:00:00"}