{"id":"https://openalex.org/W4385983388","doi":"https://doi.org/10.1016/j.exphem.2023.06.049","title":"2012 \u2013 IMMUNOPROTEASOME FUNCTION MAINTAINS ONCOGENIC GENE EXPRESSION IN KMT2A-COMPLEX DRIVEN LEUKEMIA","display_name":"2012 \u2013 IMMUNOPROTEASOME FUNCTION MAINTAINS ONCOGENIC GENE EXPRESSION IN KMT2A-COMPLEX DRIVEN LEUKEMIA","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4385983388","doi":"https://doi.org/10.1016/j.exphem.2023.06.049"},"language":"en","primary_location":{"id":"doi:10.1016/j.exphem.2023.06.049","doi":"https://doi.org/10.1016/j.exphem.2023.06.049","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.exphem.2023.06.049","pdf_url":null,"source":{"id":"https://openalex.org/S72188638","display_name":"Experimental Hematology","issn_l":"0301-472X","issn":["0301-472X","1873-2399"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Hematology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.exphem.2023.06.049","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101801412","display_name":"Florian Heinrich Heidel","orcid":"https://orcid.org/0000-0003-2438-1955","observed_orcids":["https://orcid.org/0000-0003-2438-1955"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Florian Heidel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014254807","display_name":"Nuria Tub\u00edo Santamar\u00eda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nuria Tubio-Santamaria","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039435465","display_name":"Ashok Kumar Jayavelu","orcid":"https://orcid.org/0000-0002-3292-1117","observed_orcids":["https://orcid.org/0000-0002-3292-1117"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ashok Kumar Jayavelu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030818213","display_name":"Tina M. Schnoeder","orcid":"https://orcid.org/0000-0002-6351-4119","observed_orcids":["https://orcid.org/0000-0002-6351-4119"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tina Schnoeder","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076591141","display_name":"Theresa Eifert","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Theresa Eifert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012209222","display_name":"Chen-Jen Hsu","orcid":"https://orcid.org/0000-0002-8259-7650","observed_orcids":["https://orcid.org/0000-0002-8259-7650"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chen-Jen Hsu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076222499","display_name":"Florian Perner","orcid":"https://orcid.org/0000-0003-1010-3321","observed_orcids":["https://orcid.org/0000-0003-1010-3321"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Florian Perner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Qirui Zhang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qirui Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014885323","display_name":"Daniela Vanessa Wenge","orcid":"https://orcid.org/0000-0002-0064-9104","observed_orcids":["https://orcid.org/0000-0002-0064-9104"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniela Wenge","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090688128","display_name":"Fynn M. Hansen","orcid":"https://orcid.org/0000-0002-0370-8173","observed_orcids":["https://orcid.org/0000-0002-0370-8173"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fynn Hansen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026702465","display_name":"Nidhi Jyotsana","orcid":"https://orcid.org/0000-0003-2090-2856","observed_orcids":["https://orcid.org/0000-0003-2090-2856"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nidhi jyotsana","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084825146","display_name":"Steven Lane","orcid":"https://orcid.org/0000-0002-8050-6209","observed_orcids":["https://orcid.org/0000-0002-8050-6209"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven Lane","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035995414","display_name":"Bj\u00f6rn von Ey\u00df","orcid":"https://orcid.org/0000-0002-4731-6841","observed_orcids":["https://orcid.org/0000-0002-4731-6841"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bj\u00f6rn von Eyss","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009399465","display_name":"Aniruddha J. Deshpande","orcid":"https://orcid.org/0000-0002-5240-9356","observed_orcids":["https://orcid.org/0000-0002-5240-9356"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aniruddha Deshpande","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102759810","display_name":"Michael W.M. K\u00fchn","orcid":"https://orcid.org/0000-0002-6434-9303","observed_orcids":["https://orcid.org/0000-0002-6434-9303"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael K\u00fchn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030763668","display_name":"Juerg Schwaller","orcid":"https://orcid.org/0000-0001-8616-0096","observed_orcids":["https://orcid.org/0000-0001-8616-0096"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J\u00fcrg Schwaller","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003369284","display_name":"Fr\u00e9d\u00e9ric Ebstein","orcid":"https://orcid.org/0000-0002-3729-7878","observed_orcids":["https://orcid.org/0000-0002-3729-7878"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Frederic Ebstein","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112367383","display_name":"Elke Kr\u00fcger","orcid":"https://orcid.org/0000-0002-2551-242X","observed_orcids":["https://orcid.org/0000-0002-2551-242X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elke Kr\u00fcger","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035964802","display_name":"Andreas Hochhaus","orcid":"https://orcid.org/0000-0003-0626-0834","observed_orcids":["https://orcid.org/0000-0003-0626-0834"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andreas Hochhaus","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053578678","display_name":"Michael Heuser","orcid":"https://orcid.org/0000-0001-5318-9044","observed_orcids":["https://orcid.org/0000-0001-5318-9044"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Heuser","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033394394","display_name":"Alessandro Ori\u202c\u202c","orcid":"https://orcid.org/0000-0002-3046-0871","observed_orcids":["https://orcid.org/0000-0002-3046-0871"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"alessandro Ori","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090940750","display_name":"Matthias Mann","orcid":"https://orcid.org/0000-0003-1292-4799","observed_orcids":["https://orcid.org/0000-0003-1292-4799","https://orcid.org/0000-0002-7122-6379"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthias Mann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5012956545","display_name":"Scott A. Armstrong","orcid":"https://orcid.org/0000-0002-9099-4728","observed_orcids":["https://orcid.org/0000-0002-9099-4728"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott Armstrong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.0792,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.28850948,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":95},"biblio":{"volume":"124","issue":null,"first_page":"S42","last_page":"S42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.2345000058412552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.2345000058412552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.19869999587535858,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12534","display_name":"Protein Degradation and Inhibitors","score":0.13529999554157257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immunoproteasome","display_name":"immunoproteasome","score":0.996999979019165},{"id":"https://openalex.org/keywords/leukemia","display_name":"leukemia","score":0.6700000166893005},{"id":"https://openalex.org/keywords/oncogene-expression","display_name":"oncogene expression","score":0.859000027179718},{"id":"https://openalex.org/keywords/histone-methyltransferase","display_name":"histone methyltransferase","score":0.6850000023841858},{"id":"https://openalex.org/keywords/leukemogenesis","display_name":"leukemogenesis","score":0.42399999499320984}],"concepts":[{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.6857047080993652},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5893953442573547},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.486640065908432},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.48575547337532043},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.47593143582344055},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.430732786655426},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4118875563144684},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32492369413375854},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.31027036905288696},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.10667857527732849},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.exphem.2023.06.049","doi":"https://doi.org/10.1016/j.exphem.2023.06.049","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.exphem.2023.06.049","pdf_url":null,"source":{"id":"https://openalex.org/S72188638","display_name":"Experimental Hematology","issn_l":"0301-472X","issn":["0301-472X","1873-2399"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Hematology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.exphem.2023.06.049","doi":"https://doi.org/10.1016/j.exphem.2023.06.049","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.exphem.2023.06.049","pdf_url":null,"source":{"id":"https://openalex.org/S72188638","display_name":"Experimental Hematology","issn_l":"0301-472X","issn":["0301-472X","1873-2399"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Hematology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7101808974","https://openalex.org/W2910394717","https://openalex.org/W7120626448","https://openalex.org/W4401034350","https://openalex.org/W4413753180","https://openalex.org/W4250896051","https://openalex.org/W7161999118","https://openalex.org/W4416842575","https://openalex.org/W7037967216","https://openalex.org/W1967959896"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2023-08-19T00:00:00"}