{"id":"https://openalex.org/W4385897481","doi":"https://doi.org/10.1007/s11060-023-04417-0","title":"T2-FLAIR mismatch sign correlates with 11C-methionine uptake in lower-grade diffuse gliomas","display_name":"T2-FLAIR mismatch sign correlates with 11C-methionine uptake in lower-grade diffuse gliomas","publication_year":2023,"publication_date":"2023-08-01","ids":{"openalex":"https://openalex.org/W4385897481","doi":"https://doi.org/10.1007/s11060-023-04417-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/37589920"},"language":"en","primary_location":{"id":"doi:10.1007/s11060-023-04417-0","doi":"https://doi.org/10.1007/s11060-023-04417-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11060-023-04417-0","pdf_url":null,"source":{"id":"https://openalex.org/S175922936","display_name":"Journal of Neuro-Oncology","issn_l":"0167-594X","issn":["0167-594X","1573-7373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuro-Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083011984","display_name":"Yusuke Ebiko","orcid":"https://orcid.org/0000-0001-7861-0202","observed_orcids":["https://orcid.org/0000-0001-7861-0202"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yusuke Ebiko","raw_affiliation_strings":["Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan","institution_ids":["https://openalex.org/I125602781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011930120","display_name":"Kaoru Tamura","orcid":"https://orcid.org/0000-0002-7943-5458","observed_orcids":["https://orcid.org/0000-0002-7943-5458"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kaoru Tamura","raw_affiliation_strings":["Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan. tamura.nsrg@tmd.ac.jp","Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan"],"raw_orcid":"https://orcid.org/0000-0002-7943-5458","affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan. tamura.nsrg@tmd.ac.jp","institution_ids":["https://openalex.org/I125602781"]},{"raw_affiliation_string":"Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan","institution_ids":["https://openalex.org/I125602781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039440545","display_name":"Shoko Hara","orcid":"https://orcid.org/0000-0003-1097-2738","observed_orcids":["https://orcid.org/0000-0003-1097-2738"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I4210140609","display_name":"Tokyo Metropolitan Institute of Gerontology","ror":"https://ror.org/03rd0p893","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210140609"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shoko Hara","raw_affiliation_strings":["Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan","Research Team of Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan","institution_ids":["https://openalex.org/I125602781"]},{"raw_affiliation_string":"Research Team of Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan","institution_ids":["https://openalex.org/I4210140609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045738456","display_name":"Motoki Inaji","orcid":"https://orcid.org/0000-0002-6759-5729","observed_orcids":["https://orcid.org/0000-0002-6759-5729"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I4210140609","display_name":"Tokyo Metropolitan Institute of Gerontology","ror":"https://ror.org/03rd0p893","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210140609"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Motoki Inaji","raw_affiliation_strings":["Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan","Research Team of Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan","institution_ids":["https://openalex.org/I125602781"]},{"raw_affiliation_string":"Research Team of Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan","institution_ids":["https://openalex.org/I4210140609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036336235","display_name":"Yoji Tanaka","orcid":"https://orcid.org/0000-0002-2433-924X","observed_orcids":["https://orcid.org/0000-0002-2433-924X"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoji Tanaka","raw_affiliation_strings":["Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan","institution_ids":["https://openalex.org/I125602781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045616103","display_name":"Tadashi Nariai","orcid":"https://orcid.org/0000-0001-8819-4855","observed_orcids":["https://orcid.org/0000-0001-8819-4855"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I4210140609","display_name":"Tokyo Metropolitan Institute of Gerontology","ror":"https://ror.org/03rd0p893","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210140609"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tadashi Nariai","raw_affiliation_strings":["Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan","Research Team of Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan","institution_ids":["https://openalex.org/I125602781"]},{"raw_affiliation_string":"Research Team of Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan","institution_ids":["https://openalex.org/I4210140609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074027917","display_name":"Kenji Ishii","orcid":"https://orcid.org/0000-0002-2928-0072","observed_orcids":["https://orcid.org/0000-0002-2928-0072"]},"institutions":[{"id":"https://openalex.org/I4210140609","display_name":"Tokyo Metropolitan Institute of Gerontology","ror":"https://ror.org/03rd0p893","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210140609"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenji Ishii","raw_affiliation_strings":["Research Team of Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Team of Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan","institution_ids":["https://openalex.org/I4210140609"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041515292","display_name":"Taketoshi Maehara","orcid":"https://orcid.org/0000-0001-6804-4665","observed_orcids":["https://orcid.org/0000-0001-6804-4665"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Taketoshi Maehara","raw_affiliation_strings":["Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo- ku, Tokyo, 113-8519, Japan","institution_ids":["https://openalex.org/I125602781"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5011930120"],"corresponding_institution_ids":["https://openalex.org/I125602781"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":0.6016,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.63531483,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"164","issue":"1","first_page":"257","last_page":"265"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/t2-flair-mismatch-sign","display_name":"T2-FLAIR mismatch sign","score":0.8769999742507935},{"id":"https://openalex.org/keywords/11c-methionine-pet","display_name":"11C-methionine PET","score":0.9890000224113464},{"id":"https://openalex.org/keywords/idh-mutation","display_name":"IDH mutation","score":0.7789999842643738},{"id":"https://openalex.org/keywords/1p-19q-codeletion","display_name":"1p/19q codeletion","score":0.9760000109672546},{"id":"https://openalex.org/keywords/tumor-to-normal-tissue-ratio","display_name":"tumor-to-normal tissue ratio","score":0.671999990940094},{"id":"https://openalex.org/keywords/diffuse-astrocytoma","display_name":"diffuse astrocytoma","score":0.6610000133514404},{"id":"https://openalex.org/keywords/molecular-classification-of-glioma","display_name":"glioma molecular classification","score":0.628000020980835},{"id":"https://openalex.org/keywords/preoperative-imaging-biomarkers","display_name":"preoperative imaging biomarkers","score":0.4129999876022339},{"id":"https://openalex.org/keywords/idh-wild-type","display_name":"IDH-wildtype","score":0.4729999899864197}],"concepts":[{"id":"https://openalex.org/C101070640","wikidata":"https://www.wikidata.org/wiki/Q3737215","display_name":"Fluid-attenuated inversion recovery","level":3,"score":0.8995433449745178},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.7072980999946594},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.624408483505249},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.615229606628418},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.601689338684082},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.36058270931243896},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.07819023728370667}],"mesh":[{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008715","descriptor_name":"Methionine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064697","descriptor_name":"Racemethionine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11060-023-04417-0","doi":"https://doi.org/10.1007/s11060-023-04417-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11060-023-04417-0","pdf_url":null,"source":{"id":"https://openalex.org/S175922936","display_name":"Journal of Neuro-Oncology","issn_l":"0167-594X","issn":["0167-594X","1573-7373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuro-Oncology","raw_type":"journal-article"},{"id":"pmid:37589920","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37589920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuro-oncology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G8388438995","display_name":"Development of novel therapy and biomarkers for malignant brain tumors based on microRNA analysis","funder_award_id":"20K09321","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1598698200","https://openalex.org/W1812256879","https://openalex.org/W1822638906","https://openalex.org/W1986092833","https://openalex.org/W1989478116","https://openalex.org/W2020196369","https://openalex.org/W2046289133","https://openalex.org/W2048796627","https://openalex.org/W2098417097","https://openalex.org/W2103310685","https://openalex.org/W2117120484","https://openalex.org/W2121960517","https://openalex.org/W2133865472","https://openalex.org/W2135968932","https://openalex.org/W2287840016","https://openalex.org/W2329659234","https://openalex.org/W2366536035","https://openalex.org/W2594324890","https://openalex.org/W2620310855","https://openalex.org/W2624516058","https://openalex.org/W2741009225","https://openalex.org/W2750745141","https://openalex.org/W2791299900","https://openalex.org/W2792102603","https://openalex.org/W2900510547","https://openalex.org/W2904531397","https://openalex.org/W2914998138","https://openalex.org/W2969888568","https://openalex.org/W2989787836","https://openalex.org/W2999549459","https://openalex.org/W3007397778","https://openalex.org/W3026813010","https://openalex.org/W3036025215","https://openalex.org/W3119928980","https://openalex.org/W3174246647","https://openalex.org/W4213043155","https://openalex.org/W4238679142"],"related_works":["https://openalex.org/W4389522455","https://openalex.org/W3106987776","https://openalex.org/W3025102055","https://openalex.org/W2989098406","https://openalex.org/W3026813010","https://openalex.org/W2741009225","https://openalex.org/W4375956182","https://openalex.org/W2994824304","https://openalex.org/W4387095750","https://openalex.org/W4225080938"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-08-18T00:00:00"}