{"id":"https://openalex.org/W4385879653","doi":"https://doi.org/10.1098/rsos.230676","title":"Bioactivities of \u03b2-mangostin and its new glycoside derivatives synthesized by enzymatic reactions","display_name":"Bioactivities of \u03b2-mangostin and its new glycoside derivatives synthesized by enzymatic reactions","publication_year":2023,"publication_date":"2023-08-01","ids":{"openalex":"https://openalex.org/W4385879653","doi":"https://doi.org/10.1098/rsos.230676","pmid":"https://pubmed.ncbi.nlm.nih.gov/37593716","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10427817"},"language":"en","primary_location":{"id":"doi:10.1098/rsos.230676","doi":"https://doi.org/10.1098/rsos.230676","is_oa":true,"landing_page_url":"https://doi.org/10.1098/rsos.230676","pdf_url":null,"source":{"id":"https://openalex.org/S2737558550","display_name":"Royal Society Open Science","issn_l":"2054-5703","issn":["2054-5703"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Royal Society Open Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1098/rsos.230676","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069971878","display_name":"Tuoi Thi Le","orcid":"https://orcid.org/0009-0003-3157-1543","observed_orcids":["https://orcid.org/0009-0003-3157-1543"]},"institutions":[{"id":"https://openalex.org/I135822937","display_name":"Hanoi National University of Education","ror":"https://ror.org/0360g3z42","country_code":"VN","type":"education","lineage":["https://openalex.org/I135822937"]}],"countries":["VN"],"is_corresponding":true,"raw_author_name":"Tuoi Thi Le","raw_affiliation_strings":["Faculty of Biology, Hanoi National University of Education, 136 Xuan Thuy, Cau Giay, Hanoi 100000, Vietnam"],"raw_orcid":"https://orcid.org/0009-0003-3157-1543","affiliations":[{"raw_affiliation_string":"Faculty of Biology, Hanoi National University of Education, 136 Xuan Thuy, Cau Giay, Hanoi 100000, Vietnam","institution_ids":["https://openalex.org/I135822937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102814059","display_name":"Nguy\u1ec5n Thu Trang","orcid":"https://orcid.org/0000-0002-6164-6329","observed_orcids":["https://orcid.org/0000-0002-6164-6329"]},"institutions":[{"id":"https://openalex.org/I135822937","display_name":"Hanoi National University of Education","ror":"https://ror.org/0360g3z42","country_code":"VN","type":"education","lineage":["https://openalex.org/I135822937"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Nguyen Thu Trang","raw_affiliation_strings":["Faculty of Biology, Hanoi National University of Education, 136 Xuan Thuy, Cau Giay, Hanoi 100000, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Biology, Hanoi National University of Education, 136 Xuan Thuy, Cau Giay, Hanoi 100000, Vietnam","institution_ids":["https://openalex.org/I135822937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022518958","display_name":"Van Thuy Thi Pham","orcid":"https://orcid.org/0000-0001-6583-8590","observed_orcids":["https://orcid.org/0000-0001-6583-8590"]},"institutions":[{"id":"https://openalex.org/I177233841","display_name":"Vietnam National University, Hanoi","ror":"https://ror.org/02jmfj006","country_code":"VN","type":"education","lineage":["https://openalex.org/I177233841"]},{"id":"https://openalex.org/I4405276833","display_name":"Vi\u1ec7n Vi sinh v\u1eadt v\u00e0 C\u00f4ng ngh\u1ec7 sinh h\u1ecdc","ror":"https://ror.org/00er2qq93","country_code":"VN","type":"education","lineage":["https://openalex.org/I4405276833"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Van Thuy Thi Pham","raw_affiliation_strings":["Institute of Microbiology and Biotechnology, Vietnam National University, 144 Xuan Thuy, Cau Giay, Hanoi 100000, Vietnam"],"raw_orcid":"https://orcid.org/0000-0001-6583-8590","affiliations":[{"raw_affiliation_string":"Institute of Microbiology and Biotechnology, Vietnam National University, 144 Xuan Thuy, Cau Giay, Hanoi 100000, Vietnam","institution_ids":["https://openalex.org/I177233841","https://openalex.org/I4405276833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112247740","display_name":"\u0110\u1eb7ng Ng\u1ecdc Quang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135822937","display_name":"Hanoi National University of Education","ror":"https://ror.org/0360g3z42","country_code":"VN","type":"education","lineage":["https://openalex.org/I135822937"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Dang Ngoc Quang","raw_affiliation_strings":["Faculty of Chemistry, Hanoi National University of Education, 136 Xuan Thuy, Cau Giay, Hanoi 100000, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Chemistry, Hanoi National University of Education, 136 Xuan Thuy, Cau Giay, Hanoi 100000, Vietnam","institution_ids":["https://openalex.org/I135822937"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108567880","display_name":"Le Thi Phuong Hoa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135822937","display_name":"Hanoi National University of Education","ror":"https://ror.org/0360g3z42","country_code":"VN","type":"education","lineage":["https://openalex.org/I135822937"]}],"countries":["VN"],"is_corresponding":true,"raw_author_name":"Le Thi Phuong Hoa","raw_affiliation_strings":["Faculty of Biology, Hanoi National University of Education, 136 Xuan Thuy, Cau Giay, Hanoi 100000, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Biology, Hanoi National University of Education, 136 Xuan Thuy, Cau Giay, Hanoi 100000, Vietnam","institution_ids":["https://openalex.org/I135822937"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5069971878","https://openalex.org/A5108567880"],"corresponding_institution_ids":["https://openalex.org/I135822937"],"apc_list":{"value":1200,"currency":"GBP","value_usd":1471},"apc_paid":{"value":1200,"currency":"GBP","value_usd":1471},"fwci":1.5233,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.79490541,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"10","issue":"8","first_page":"230676","last_page":"230676"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12087","display_name":"Natural Compound Pharmacology Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12087","display_name":"Natural Compound Pharmacology Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13221","display_name":"Biological Activity of Diterpenoids and Biflavonoids","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13846","display_name":"Mangiferin and Mango Extracts","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/beta-mangostin","display_name":"\u03b2-mangostin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/xanthones","display_name":"xanthones","score":0.9240000247955322},{"id":"https://openalex.org/keywords/garcinia","display_name":"Garcinia","score":0.7419999837875366},{"id":"https://openalex.org/keywords/enzymatic-glycosylation","display_name":"enzymatic glycosylation","score":0.9259999990463257},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9340000152587891},{"id":"https://openalex.org/keywords/acetylcholinesterase-inhibition","display_name":"acetylcholinesterase inhibition","score":0.8429999947547913},{"id":"https://openalex.org/keywords/alpha-glucosidase-inhibition","display_name":"\u03b1-glucosidase inhibition","score":1.0},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.8939999938011169},{"id":"https://openalex.org/keywords/antifungal-activity","display_name":"antifungal activity","score":0.9629999995231628},{"id":"https://openalex.org/keywords/cancer-cell-lines","display_name":"cancer cell lines","score":0.652999997138977}],"concepts":[{"id":"https://openalex.org/C2775842281","wikidata":"https://www.wikidata.org/wiki/Q421789","display_name":"Xanthone","level":2,"score":0.7758651375770569},{"id":"https://openalex.org/C2777272437","wikidata":"https://www.wikidata.org/wiki/Q131238","display_name":"Bacillus subtilis","level":3,"score":0.6627097129821777},{"id":"https://openalex.org/C2909826119","wikidata":"https://www.wikidata.org/wiki/Q170662","display_name":"Garcinia mangostana","level":2,"score":0.6099346876144409},{"id":"https://openalex.org/C2776503186","wikidata":"https://www.wikidata.org/wiki/Q2134039","display_name":"Lactobacillus fermentum","level":5,"score":0.5574945211410522},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5564847588539124},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.5492798686027527},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.5027079582214355},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.4712287187576294},{"id":"https://openalex.org/C2777752497","wikidata":"https://www.wikidata.org/wiki/Q286779","display_name":"IC50","level":3,"score":0.43165647983551025},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.4199789762496948},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4190219044685364},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.33187103271484375},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2999131381511688},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.276214599609375},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.23116442561149597},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.13511928915977478},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.10449472069740295},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07942751049995422},{"id":"https://openalex.org/C2778985185","wikidata":"https://www.wikidata.org/wiki/Q1756682","display_name":"Lactobacillus plantarum","level":4,"score":0.0},{"id":"https://openalex.org/C2775920511","wikidata":"https://www.wikidata.org/wiki/Q161249","display_name":"Lactic acid","level":3,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1098/rsos.230676","doi":"https://doi.org/10.1098/rsos.230676","is_oa":true,"landing_page_url":"https://doi.org/10.1098/rsos.230676","pdf_url":null,"source":{"id":"https://openalex.org/S2737558550","display_name":"Royal Society Open Science","issn_l":"2054-5703","issn":["2054-5703"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Royal Society Open Science","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10427817","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10427817","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10427817/pdf/rsos.230676.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"R Soc Open Sci","raw_type":"Text"},{"id":"pmid:37593716","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37593716","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Royal Society open science","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:2244076351ec435cb4bbd1e62d4de15b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/2244076351ec435cb4bbd1e62d4de15b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Royal Society Open Science, Vol 10, Iss 8 (2023)","raw_type":"article"},{"id":"doi:10.60692/3mgq4-mb706","doi":"https://doi.org/10.60692/3mgq4-mb706","is_oa":true,"landing_page_url":"https://doi.org/10.60692/3mgq4-mb706","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/8t7dq-b8362","doi":"https://doi.org/10.60692/8t7dq-b8362","is_oa":true,"landing_page_url":"https://doi.org/10.60692/8t7dq-b8362","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1098/rsos.230676","doi":"https://doi.org/10.1098/rsos.230676","is_oa":true,"landing_page_url":"https://doi.org/10.1098/rsos.230676","pdf_url":null,"source":{"id":"https://openalex.org/S2737558550","display_name":"Royal Society Open Science","issn_l":"2054-5703","issn":["2054-5703"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Royal Society Open Science","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321340","display_name":"Sun Moon University","ror":"https://ror.org/009e5cd49"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4385879653.pdf","grobid_xml":"https://content.openalex.org/works/W4385879653.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1971048984","https://openalex.org/W1973729954","https://openalex.org/W2004018987","https://openalex.org/W2008751261","https://openalex.org/W2049365002","https://openalex.org/W2053193063","https://openalex.org/W2058928007","https://openalex.org/W2077673472","https://openalex.org/W2077912926","https://openalex.org/W2101580547","https://openalex.org/W2109626018","https://openalex.org/W2114918609","https://openalex.org/W2116642619","https://openalex.org/W2124099438","https://openalex.org/W2137267229","https://openalex.org/W2155821305","https://openalex.org/W2158984087","https://openalex.org/W2161052192","https://openalex.org/W2163446105","https://openalex.org/W2228154783","https://openalex.org/W2388603324","https://openalex.org/W2602542418","https://openalex.org/W2619752178","https://openalex.org/W2734699173","https://openalex.org/W2736714553","https://openalex.org/W2738055411","https://openalex.org/W2771750816","https://openalex.org/W2781978013","https://openalex.org/W2893930979","https://openalex.org/W2899015270","https://openalex.org/W2901306993","https://openalex.org/W2959201832","https://openalex.org/W3019144850","https://openalex.org/W3033185130","https://openalex.org/W3044663050","https://openalex.org/W3130534405","https://openalex.org/W3159907306","https://openalex.org/W3198553162","https://openalex.org/W4200307880","https://openalex.org/W4206389871","https://openalex.org/W4206435959","https://openalex.org/W4283780685","https://openalex.org/W4295846926","https://openalex.org/W4382601497","https://openalex.org/W6977242202","https://openalex.org/W6979965932","https://openalex.org/W7011642337"],"related_works":["https://openalex.org/W2077405050","https://openalex.org/W2320269889","https://openalex.org/W2077912926","https://openalex.org/W4309210814","https://openalex.org/W1868388770","https://openalex.org/W6939879693","https://openalex.org/W1964330394","https://openalex.org/W2587845897","https://openalex.org/W4401551866","https://openalex.org/W1973036811"],"abstract_inverted_index":{"Beta-mangostin":[0,72,149],"is":[1],"a":[2,19,43],"xanthone":[3],"commonly":[4],"found":[5],"in":[6,214],"the":[7,23,180,203,207],"genus":[8],"Garcinia":[9],".":[10],"Unlike":[11],"\u03b1-mangostin,":[12],"to":[13,91],"date,":[14],"there":[15],"have":[16],"only":[17],"been":[18],"few":[20],"studies":[21],"on":[22],"biological":[24],"activity":[25,117,152],"and":[26,56,64,67,79,96,110,129,142,162,175],"derivatization":[27],"of":[28,37,100,108,118,139,193,200,206,212],"\u03b2-mangostin.":[29],"In":[30],"this":[31],"study,":[32],"two":[33],"novel":[34],"glycosylated":[35],"derivatives":[36,48,192],"\u03b2-mangostin":[38,52,57,101,119,194,213],"were":[39,49,102],"successfully":[40],"synthesized":[41],"via":[42],"one-pot":[44],"enzymatic":[45],"reaction.":[46],"These":[47],"characterized":[50],"as":[51,166,168],"6-O-\u03b2-":[53,58],"d":[54,59],"-glucopyranoside":[55],"-2-deoxyglucopyranoside":[60],"by":[61],"TOF":[62],"ESI/MS":[63],"1":[65],"H":[66],"13":[68],"C":[69],"NMR":[70],"analyses.":[71],"showed":[73,150,195],"cytotoxicity":[74],"against":[75,120,153],"KB,":[76],"MCF7,":[77],"A549":[78],"HepG2":[80],"cancer":[81],"cell":[82],"lines,":[83],"with":[84,104,135,172],"IC":[85,105,136,173],"50":[86,106,137,174],"values":[87,107,138,177],"ranging":[88],"from":[89],"15.42":[90],"21.13":[92],"\u00b5M.":[93],"The":[94,190],"acetylcholinesterase":[95],"\u03b1-glucosidase":[97],"inhibitory":[98],"activities":[99,197],"determined":[103],"2.17":[109],"27.61":[111],"\u00b5M,":[112],"respectively.":[113,148],"A":[114],"strong":[115],"anti-microbial":[116],"Gram-positive":[121],"strains":[122,155],"(":[123,156],"Bacillus":[124],"subtilis":[125],",":[126,147,159],"Lactobacillus":[127],"fermentum":[128],"Staphylococcus":[130],"aureus":[131],")":[132,165],"was":[133],"observed,":[134],"0.16,":[140],"0.18":[141],"1.24":[143],"\u00b5g":[144,186],"ml":[145,187],"\u22121":[146,188],"weaker":[151,196],"Gram-negative":[154],"Salmonella":[157],"enterica":[158],"Escherichia":[160],"coli":[161],"Pseudomonas":[163],"aeruginosa":[164],"well":[167],"Candida":[169],"albicans":[170],"fungus,":[171],"MIC":[176],"greater":[178],"than":[179,184,198],"tested":[181],"concentration":[182],"(greater":[183],"32":[185],").":[189],"new":[191],"those":[199],"\u03b2-mangostin,":[201],"demonstrating":[202],"important":[204],"role":[205],"hydroxyl":[208],"group":[209],"at":[210],"C-6":[211],"its":[215],"bioactivity.":[216]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-08-17T00:00:00"}