{"id":"https://openalex.org/W4385803079","doi":"https://doi.org/10.1021/acsami.3c06709","title":"Hydrophobic Gating and Spatial Confinement in Hierarchically Organized Block Copolymer-Nanopore Electrode Arrays for Electrochemical Biosensing of 4-Ethyl Phenol","display_name":"Hydrophobic Gating and Spatial Confinement in Hierarchically Organized Block Copolymer-Nanopore Electrode Arrays for Electrochemical Biosensing of 4-Ethyl Phenol","publication_year":2023,"publication_date":"2023-08-14","ids":{"openalex":"https://openalex.org/W4385803079","doi":"https://doi.org/10.1021/acsami.3c06709","pmid":"https://pubmed.ncbi.nlm.nih.gov/37579252"},"language":"en","primary_location":{"id":"doi:10.1021/acsami.3c06709","doi":"https://doi.org/10.1021/acsami.3c06709","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsami.3c06709","pdf_url":null,"source":{"id":"https://openalex.org/S164001016","display_name":"ACS Applied Materials & Interfaces","issn_l":"1944-8244","issn":["1944-8244","1944-8252"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Applied Materials &amp; Interfaces","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/journal_contribution/Hydrophobic_Gating_and_Spatial_Confinement_in_Hierarchically_Organized_Block_Copolymer-Nanopore_Electrode_Arrays_for_Electrochemical_Biosensing_of_4-Ethyl_Phenol/24968757","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019917454","display_name":"Julius Reitemeier","orcid":"https://orcid.org/0000-0001-6656-240X","observed_orcids":["https://orcid.org/0000-0001-6656-240X"]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julius Reitemeier","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States"],"raw_orcid":"https://orcid.org/0000-0001-6656-240X","affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091308923","display_name":"Seol Baek","orcid":"https://orcid.org/0000-0003-2191-6723","observed_orcids":["https://orcid.org/0000-0003-2191-6723"]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seol Baek","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090209222","display_name":"Paul W. Bohn","orcid":"https://orcid.org/0000-0001-9052-0349","observed_orcids":["https://orcid.org/0000-0001-9052-0349"]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Paul W. Bohn","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, United States","Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States"],"raw_orcid":"https://orcid.org/0000-0001-9052-0349","affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, United States","institution_ids":["https://openalex.org/I107639228"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States","institution_ids":["https://openalex.org/I107639228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5090209222"],"corresponding_institution_ids":["https://openalex.org/I107639228"],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":1.6304,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.82943531,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"15","issue":"33","first_page":"39707","last_page":"39715"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.6187000274658203,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.6187000274658203,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11582","display_name":"Nanopore and Nanochannel Transport Studies","score":0.3546999990940094,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11434","display_name":"Electrochemical Analysis and Applications","score":0.016100000590085983,"subfield":{"id":"https://openalex.org/subfields/1603","display_name":"Electrochemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hydrophobic-gating","display_name":"hydrophobic gating","score":0.9470000267028809},{"id":"https://openalex.org/keywords/block-copolymers","display_name":"block copolymers","score":0.9279999732971191},{"id":"https://openalex.org/keywords/polystyrene-b-poly-4-vinylpyridine","display_name":"polystyrene-b-poly(4-vinylpyridine)","score":0.906000018119812},{"id":"https://openalex.org/keywords/tyrosinase","display_name":"tyrosinase","score":0.9670000076293945},{"id":"https://openalex.org/keywords/4-ethylphenol","display_name":"4-ethylphenol","score":0.8320000171661377},{"id":"https://openalex.org/keywords/electrochemical-biosensor","display_name":"electrochemical biosensor","score":0.7929999828338623},{"id":"https://openalex.org/keywords/spatial-confinement","display_name":"spatial confinement","score":0.6190000176429749},{"id":"https://openalex.org/keywords/mass-transport-control","display_name":"mass transport control","score":0.7850000262260437},{"id":"https://openalex.org/keywords/point-of-care-devices","display_name":"point-of-care devices","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7315568327903748},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.7194474935531616},{"id":"https://openalex.org/C141795571","wikidata":"https://www.wikidata.org/wiki/Q580942","display_name":"Nanopore","level":2,"score":0.7186257839202881},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6232187747955322},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.5859801769256592},{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.4293510913848877},{"id":"https://openalex.org/C55904794","wikidata":"https://www.wikidata.org/wiki/Q82682","display_name":"Redox","level":2,"score":0.42411476373672485},{"id":"https://openalex.org/C194544171","wikidata":"https://www.wikidata.org/wiki/Q21105679","display_name":"Gating","level":2,"score":0.41969791054725647},{"id":"https://openalex.org/C2777197210","wikidata":"https://www.wikidata.org/wiki/Q419321","display_name":"Glucose oxidase","level":3,"score":0.4113766551017761},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.17799663543701172},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.07873669266700745},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014442","descriptor_name":"Monophenol Monooxygenase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058608","descriptor_name":"Nanopores","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1021/acsami.3c06709","doi":"https://doi.org/10.1021/acsami.3c06709","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsami.3c06709","pdf_url":null,"source":{"id":"https://openalex.org/S164001016","display_name":"ACS Applied Materials & Interfaces","issn_l":"1944-8244","issn":["1944-8244","1944-8252"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Applied Materials &amp; Interfaces","raw_type":"journal-article"},{"id":"pmid:37579252","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37579252","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS applied materials & interfaces","raw_type":"Journal Article"},{"id":"pmh:oai:figshare.com:article/24968757","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Hydrophobic_Gating_and_Spatial_Confinement_in_Hierarchically_Organized_Block_Copolymer-Nanopore_Electrode_Arrays_for_Electrochemical_Biosensing_of_4-Ethyl_Phenol/24968757","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"doi:10.7274/24968757","doi":"https://doi.org/10.7274/24968757","is_oa":true,"landing_page_url":"https://doi.org/10.7274/24968757","pdf_url":null,"source":{"id":"https://openalex.org/S7407053147","display_name":"University of Notre Dame","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.7274/24968757.v1","doi":"https://doi.org/10.7274/24968757.v1","is_oa":true,"landing_page_url":"https://doi.org/10.7274/24968757.v1","pdf_url":null,"source":{"id":"https://openalex.org/S7407053147","display_name":"University of Notre Dame","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/24968757","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Hydrophobic_Gating_and_Spatial_Confinement_in_Hierarchically_Organized_Block_Copolymer-Nanopore_Electrode_Arrays_for_Electrochemical_Biosensing_of_4-Ethyl_Phenol/24968757","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2398144818","display_name":null,"funder_award_id":"1476-2220","funder_id":"https://openalex.org/F4320332467","funder_display_name":"U.S. Air Force"},{"id":"https://openalex.org/G5916739656","display_name":null,"funder_award_id":"NSF 2303574","funder_id":"https://openalex.org/F4320337393","funder_display_name":"Division of Chemistry"}],"funders":[{"id":"https://openalex.org/F4320332467","display_name":"U.S. Air Force","ror":"https://ror.org/006gmme17"},{"id":"https://openalex.org/F4320337393","display_name":"Division of Chemistry","ror":"https://ror.org/01ar8dr59"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W75385342","https://openalex.org/W1915320571","https://openalex.org/W1963480981","https://openalex.org/W1963624984","https://openalex.org/W1963924039","https://openalex.org/W1964334493","https://openalex.org/W1979453774","https://openalex.org/W1980223691","https://openalex.org/W1999838269","https://openalex.org/W2012138685","https://openalex.org/W2020831992","https://openalex.org/W2025927105","https://openalex.org/W2028837069","https://openalex.org/W2029977206","https://openalex.org/W2030345951","https://openalex.org/W2056159647","https://openalex.org/W2056485178","https://openalex.org/W2059118261","https://openalex.org/W2064580674","https://openalex.org/W2082971079","https://openalex.org/W2089042562","https://openalex.org/W2089675977","https://openalex.org/W2097580591","https://openalex.org/W2104129019","https://openalex.org/W2135902765","https://openalex.org/W2145586921","https://openalex.org/W2150197829","https://openalex.org/W2181233569","https://openalex.org/W2190425872","https://openalex.org/W2292692353","https://openalex.org/W2315156931","https://openalex.org/W2320290526","https://openalex.org/W2333610066","https://openalex.org/W2411093777","https://openalex.org/W2472037541","https://openalex.org/W2519070930","https://openalex.org/W2535849056","https://openalex.org/W2604088485","https://openalex.org/W2606906907","https://openalex.org/W2682761804","https://openalex.org/W2789801343","https://openalex.org/W2793824367","https://openalex.org/W2886066723","https://openalex.org/W2904492745","https://openalex.org/W2917793682","https://openalex.org/W2975789532","https://openalex.org/W3003528154","https://openalex.org/W3011228191","https://openalex.org/W3012271617","https://openalex.org/W3015214460","https://openalex.org/W3031422634","https://openalex.org/W3043714455","https://openalex.org/W3088197158","https://openalex.org/W3109811951","https://openalex.org/W3194927328","https://openalex.org/W3196558387","https://openalex.org/W4200347174","https://openalex.org/W4220670432","https://openalex.org/W4220717090","https://openalex.org/W4223457486","https://openalex.org/W4283261050","https://openalex.org/W4307856621","https://openalex.org/W4321003191"],"related_works":["https://openalex.org/W6977840887","https://openalex.org/W3109811951","https://openalex.org/W4416569823","https://openalex.org/W2981740758","https://openalex.org/W2709599193","https://openalex.org/W2888126592","https://openalex.org/W2120777399","https://openalex.org/W3131038377","https://openalex.org/W2056723134","https://openalex.org/W4389215718"],"abstract_inverted_index":{"Hydrophobic":[0],"gating":[1,100],"in":[2,134,155,188,224],"biological":[3],"transport":[4,21,58,104,200],"proteins":[5],"is":[6,105,206],"regulated":[7],"by":[8,24,114],"stimulus-specific":[9],"switching":[10],"between":[11],"filled":[12],"and":[13,45,47,107,130,145,217,222],"empty":[14],"nanocavities,":[15],"endowing":[16],"them":[17],"with":[18,67,98,149],"selective":[19,218],"mass":[20,57,199],"capabilities.":[22],"Inspired":[23],"these,":[25],"solid-state":[26],"nanochannels":[27,113],"have":[28],"been":[29],"integrated":[30],"into":[31,173],"functional":[32],"materials":[33],"for":[34,81,215],"a":[35,156,193],"broad":[36],"range":[37],"of":[38,117,122,138,195,211,220],"applications,":[39],"such":[40],"as":[41,77],"energy":[42],"conversion,":[43],"filtration,":[44],"nanoelectronics,":[46],"here":[48,205],"we":[49,62],"extend":[50],"these":[51],"to":[52,56,128,183,208],"electrochemical":[53,79],"biosensors":[54,80,214],"coupled":[55],"control":[59],"elements.":[60],"Specifically,":[61],"report":[63],"hierarchically":[64],"organized":[65],"structures":[66],"block":[68],"copolymers":[69],"on":[70],"tyrosinase-modified":[71],"two-electrode":[72],"nanopore":[73,140],"electrode":[74],"arrays":[75],"(BCP@NEAs)":[76],"stimulus-controlled":[78],"alkylphenols.":[82],"A":[83],"polystyrene-":[84],"b":[85,88],"-poly(4-vinyl)pyridine":[86],"(PS-":[87],"-P4VP)":[89],"membrane":[90],"placed":[91],"atop":[92],"the":[93,96,115,135,170,179,209],"NEA":[94],"endows":[95],"system":[97],"potential-responsive":[99],"properties,":[101],"where":[102],"water":[103],"spatially":[106],"temporarily":[108],"gated":[109],"through":[110],"hydrophobic":[111,123],"P4VP":[112],"application":[116],"appropriate":[118],"potentials.":[119],"The":[120,159,198],"reversibility":[121],"voltage-gating":[124],"makes":[125],"it":[126],"possible":[127],"capture":[129],"confine":[131],"analyte":[132],"species":[133],"attoliter-volume":[136],"vestibule":[137],"cylindrical":[139],"electrodes,":[141],"enabling":[142],"redox":[143,181],"cycling":[144,186],"yielding":[146],"enhanced":[147],"currents":[148,187],"amplification":[150],"factors":[151],">100\u00d7":[152],"when":[153],"operated":[154],"generator-collector":[157],"mode.":[158],"enzyme-coupled":[160,212],"sensing":[161,202],"capabilities":[162],"are":[163],"demonstrated":[164],"using":[165,178],"nonelectroactive":[166],"4-ethyl":[167],"phenol,":[168],"exploiting":[169],"tyrosinase-catalyzed":[171],"turnover":[172],"reversibly":[174],"redox-active":[175],"quinones,":[176],"then":[177],"quinone-catechol":[180],"reaction":[182],"achieve":[184],"ultrasensitive":[185],"confined":[189],"BCP@NEA":[190],"sensors":[191],"giving":[192],"limit-of-detection":[194],"\u223c120":[196],"nM.":[197],"controlled":[201],"platform":[203],"described":[204],"relevant":[207],"development":[210],"multiplex":[213],"sensitive":[216],"detection":[219],"biomarkers":[221],"metabolites":[223],"next-generation":[225],"point-of-care":[226],"devices.":[227]},"counts_by_year":[{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-08-15T00:00:00"}
