{"id":"https://openalex.org/W4385754635","doi":"https://doi.org/10.3390/biotech12030054","title":"Characterization of Enzyme-Linked Immunosorbent Assay (ELISA) for Quantification of Antibodies against Salmonella Typhimurium and Salmonella Enteritidis O-Antigens in Human Sera","display_name":"Characterization of Enzyme-Linked Immunosorbent Assay (ELISA) for Quantification of Antibodies against Salmonella Typhimurium and Salmonella Enteritidis O-Antigens in Human Sera","publication_year":2023,"publication_date":"2023-08-11","ids":{"openalex":"https://openalex.org/W4385754635","doi":"https://doi.org/10.3390/biotech12030054","pmid":"https://pubmed.ncbi.nlm.nih.gov/37606441"},"language":"en","primary_location":{"id":"doi:10.3390/biotech12030054","doi":"https://doi.org/10.3390/biotech12030054","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biotech12030054","pdf_url":"https://www.mdpi.com/2673-6284/12/3/54/pdf?version=1691746860","source":{"id":"https://openalex.org/S4210174294","display_name":"BioTech","issn_l":"2673-6284","issn":["2673-6284"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioTech","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2673-6284/12/3/54/pdf?version=1691746860","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058256966","display_name":"Maria Grazia Aruta","orcid":"https://orcid.org/0000-0002-9248-9362","observed_orcids":["https://orcid.org/0000-0002-9248-9362"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria Grazia Aruta","raw_affiliation_strings":["GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy"],"raw_orcid":"https://orcid.org/0000-0002-9248-9362","affiliations":[{"raw_affiliation_string":"GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106944334","display_name":"Elisa Lari","orcid":"https://orcid.org/0009-0009-2362-2199","observed_orcids":["https://orcid.org/0009-0009-2362-2199"]},"institutions":[{"id":"https://openalex.org/I4210164598","display_name":"VisMederi (Italy)","ror":"https://ror.org/05sv6xe54","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210164598"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elisa Lari","raw_affiliation_strings":["VisMederi S.r.l., 53100 Siena, Italy"],"raw_orcid":"https://orcid.org/0009-0009-2362-2199","affiliations":[{"raw_affiliation_string":"VisMederi S.r.l., 53100 Siena, Italy","institution_ids":["https://openalex.org/I4210164598"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000560511","display_name":"Daniele De Simone","orcid":"https://orcid.org/0009-0009-0727-4761","observed_orcids":["https://orcid.org/0009-0009-0727-4761"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniele De Simone","raw_affiliation_strings":["GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015994695","display_name":"Bianca Semplici","orcid":"https://orcid.org/0009-0005-8914-1866","observed_orcids":["https://orcid.org/0009-0005-8914-1866"]},"institutions":[{"id":"https://openalex.org/I4210164598","display_name":"VisMederi (Italy)","ror":"https://ror.org/05sv6xe54","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210164598"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Bianca Semplici","raw_affiliation_strings":["VisMederi S.r.l., 53100 Siena, Italy"],"raw_orcid":"https://orcid.org/0009-0005-8914-1866","affiliations":[{"raw_affiliation_string":"VisMederi S.r.l., 53100 Siena, Italy","institution_ids":["https://openalex.org/I4210164598"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058424910","display_name":"Claudia Semplici","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164598","display_name":"VisMederi (Italy)","ror":"https://ror.org/05sv6xe54","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210164598"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Claudia Semplici","raw_affiliation_strings":["VisMederi S.r.l., 53100 Siena, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VisMederi S.r.l., 53100 Siena, Italy","institution_ids":["https://openalex.org/I4210164598"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073031438","display_name":"Helen Dale","orcid":"https://orcid.org/0000-0002-4171-1226","observed_orcids":["https://orcid.org/0000-0002-4171-1226"]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]},{"id":"https://openalex.org/I2799451200","display_name":"Malawi-Liverpool-Wellcome Trust Clinical Research Programme","ror":"https://ror.org/03tebt685","country_code":"MW","type":"facility","lineage":["https://openalex.org/I157591606","https://openalex.org/I2799451200","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I4403928428","display_name":"Kamuzu University of Health Sciences","ror":"https://ror.org/00khnq787","country_code":"MW","type":"education","lineage":["https://openalex.org/I4403928428"]}],"countries":["GB","MW"],"is_corresponding":false,"raw_author_name":"Helen Dale","raw_affiliation_strings":["Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 3BX, UK","Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 3BX, UK","institution_ids":["https://openalex.org/I146655781"]},{"raw_affiliation_string":"Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","institution_ids":["https://openalex.org/I2799451200"]},{"raw_affiliation_string":"Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi","institution_ids":["https://openalex.org/I4403928428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039155012","display_name":"Esmelda B. Chirwa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]},{"id":"https://openalex.org/I2799451200","display_name":"Malawi-Liverpool-Wellcome Trust Clinical Research Programme","ror":"https://ror.org/03tebt685","country_code":"MW","type":"facility","lineage":["https://openalex.org/I157591606","https://openalex.org/I2799451200","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I4403928428","display_name":"Kamuzu University of Health Sciences","ror":"https://ror.org/00khnq787","country_code":"MW","type":"education","lineage":["https://openalex.org/I4403928428"]}],"countries":["GB","MW"],"is_corresponding":false,"raw_author_name":"Esmelda Chirwa","raw_affiliation_strings":["Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 3BX, UK","Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 3BX, UK","institution_ids":["https://openalex.org/I146655781"]},{"raw_affiliation_string":"Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","institution_ids":["https://openalex.org/I2799451200"]},{"raw_affiliation_string":"Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi","institution_ids":["https://openalex.org/I4403928428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041887003","display_name":"Innocent Kadwala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799451200","display_name":"Malawi-Liverpool-Wellcome Trust Clinical Research Programme","ror":"https://ror.org/03tebt685","country_code":"MW","type":"facility","lineage":["https://openalex.org/I157591606","https://openalex.org/I2799451200","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I4403928428","display_name":"Kamuzu University of Health Sciences","ror":"https://ror.org/00khnq787","country_code":"MW","type":"education","lineage":["https://openalex.org/I4403928428"]}],"countries":["MW"],"is_corresponding":false,"raw_author_name":"Innocent Kadwala","raw_affiliation_strings":["Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","institution_ids":["https://openalex.org/I2799451200"]},{"raw_affiliation_string":"Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi","institution_ids":["https://openalex.org/I4403928428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014103708","display_name":"Maurice Mbewe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799451200","display_name":"Malawi-Liverpool-Wellcome Trust Clinical Research Programme","ror":"https://ror.org/03tebt685","country_code":"MW","type":"facility","lineage":["https://openalex.org/I157591606","https://openalex.org/I2799451200","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I4403928428","display_name":"Kamuzu University of Health Sciences","ror":"https://ror.org/00khnq787","country_code":"MW","type":"education","lineage":["https://openalex.org/I4403928428"]}],"countries":["MW"],"is_corresponding":false,"raw_author_name":"Maurice Mbewe","raw_affiliation_strings":["Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","institution_ids":["https://openalex.org/I2799451200"]},{"raw_affiliation_string":"Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi","institution_ids":["https://openalex.org/I4403928428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002453345","display_name":"Happy Banda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799451200","display_name":"Malawi-Liverpool-Wellcome Trust Clinical Research Programme","ror":"https://ror.org/03tebt685","country_code":"MW","type":"facility","lineage":["https://openalex.org/I157591606","https://openalex.org/I2799451200","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I4403928428","display_name":"Kamuzu University of Health Sciences","ror":"https://ror.org/00khnq787","country_code":"MW","type":"education","lineage":["https://openalex.org/I4403928428"]}],"countries":["MW"],"is_corresponding":false,"raw_author_name":"Happy Banda","raw_affiliation_strings":["Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","institution_ids":["https://openalex.org/I2799451200"]},{"raw_affiliation_string":"Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi","institution_ids":["https://openalex.org/I4403928428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070614747","display_name":"Miren Iturriza\u2010G\u00f3mara","orcid":"https://orcid.org/0000-0001-5816-6423","observed_orcids":["https://orcid.org/0000-0001-5816-6423"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Miren Iturriza-Gomara","raw_affiliation_strings":["GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071606984","display_name":"Melita A. Gordon","orcid":"https://orcid.org/0000-0002-0629-0884","observed_orcids":["https://orcid.org/0000-0002-0629-0884"]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]},{"id":"https://openalex.org/I2799451200","display_name":"Malawi-Liverpool-Wellcome Trust Clinical Research Programme","ror":"https://ror.org/03tebt685","country_code":"MW","type":"facility","lineage":["https://openalex.org/I157591606","https://openalex.org/I2799451200","https://openalex.org/I87048295"]}],"countries":["GB","MW"],"is_corresponding":false,"raw_author_name":"Melita Gordon","raw_affiliation_strings":["Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 3BX, UK","Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 3BX, UK","institution_ids":["https://openalex.org/I146655781"]},{"raw_affiliation_string":"Malawi Liverpool Wellcome Trust Programme, Blantyre 30096, Malawi","institution_ids":["https://openalex.org/I2799451200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067151769","display_name":"Tonney S. Nyirenda","orcid":"https://orcid.org/0000-0002-4874-9518","observed_orcids":["https://orcid.org/0000-0002-4874-9518"]},"institutions":[{"id":"https://openalex.org/I4403928428","display_name":"Kamuzu University of Health Sciences","ror":"https://ror.org/00khnq787","country_code":"MW","type":"education","lineage":["https://openalex.org/I4403928428"]}],"countries":["MW"],"is_corresponding":false,"raw_author_name":"Tonney Nyirenda","raw_affiliation_strings":["Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology Department, Kamuzu University of Health Sciences, Blantyre 312225, Malawi","institution_ids":["https://openalex.org/I4403928428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049781577","display_name":"Pietro Piu","orcid":"https://orcid.org/0000-0002-7504-1822","observed_orcids":["https://orcid.org/0000-0002-7504-1822"]},"institutions":[{"id":"https://openalex.org/I4210164598","display_name":"VisMederi (Italy)","ror":"https://ror.org/05sv6xe54","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210164598"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Pietro Piu","raw_affiliation_strings":["VisMederi S.r.l., 53100 Siena, Italy"],"raw_orcid":"https://orcid.org/0000-0002-7504-1822","affiliations":[{"raw_affiliation_string":"VisMederi S.r.l., 53100 Siena, Italy","institution_ids":["https://openalex.org/I4210164598"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006985309","display_name":"Mariagrazia Pizza","orcid":"https://orcid.org/0000-0002-7800-1404","observed_orcids":["https://orcid.org/0000-0002-7800-1404"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mariagrazia Pizza","raw_affiliation_strings":["GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy","Imperial College South Kensington Campus, London SW7 2AZ, UK"],"raw_orcid":"https://orcid.org/0000-0002-7800-1404","affiliations":[{"raw_affiliation_string":"GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy","institution_ids":[]},{"raw_affiliation_string":"Imperial College South Kensington Campus, London SW7 2AZ, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022945764","display_name":"Francesco Berlanda Scorza","orcid":"https://orcid.org/0000-0003-2307-7855","observed_orcids":["https://orcid.org/0000-0003-2307-7855"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francesco Berlanda Scorza","raw_affiliation_strings":["GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004679459","display_name":"Silvia Grappi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164598","display_name":"VisMederi (Italy)","ror":"https://ror.org/05sv6xe54","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210164598"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Silvia Grappi","raw_affiliation_strings":["VisMederi S.r.l., 53100 Siena, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VisMederi S.r.l., 53100 Siena, Italy","institution_ids":["https://openalex.org/I4210164598"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027510766","display_name":"Roc\u0131\u0301o Canals","orcid":"https://orcid.org/0000-0001-7079-7690","observed_orcids":["https://orcid.org/0000-0001-7079-7690"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Roc\u00edo Canals","raw_affiliation_strings":["GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy"],"raw_orcid":"https://orcid.org/0000-0001-7079-7690","affiliations":[{"raw_affiliation_string":"GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030919190","display_name":"Omar Rossi","orcid":"https://orcid.org/0000-0002-0170-1285","observed_orcids":["https://orcid.org/0000-0002-0170-1285","https://orcid.org/0000-0002-6116-9892"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Omar Rossi","raw_affiliation_strings":["GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy"],"raw_orcid":"https://orcid.org/0000-0002-0170-1285","affiliations":[{"raw_affiliation_string":"GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5030919190"],"corresponding_institution_ids":[],"apc_list":{"value":1400,"currency":"CHF","value_usd":1557},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1557},"fwci":2.6868,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.8921311,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"12","issue":"3","first_page":"54","last_page":"54"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salmonella-typhimurium","display_name":"Salmonella typhimurium","score":0.8410000205039978},{"id":"https://openalex.org/keywords/salmonella-enteritidis","display_name":"Salmonella Enteritidis","score":1.0},{"id":"https://openalex.org/keywords/o-antigen-antibodies","display_name":"O antigen antibodies","score":0.8550000190734863},{"id":"https://openalex.org/keywords/non-typhoidal-salmonella","display_name":"non-typhoidal Salmonella","score":0.8460000157356262},{"id":"https://openalex.org/keywords/igg-quantification","display_name":"IgG quantification","score":0.7770000100135803},{"id":"https://openalex.org/keywords/assay-standardization","display_name":"assay standardization","score":0.7080000042915344},{"id":"https://openalex.org/keywords/vaccine-immunogenicity","display_name":"vaccine immunogenicity","score":0.746999979019165},{"id":"https://openalex.org/keywords/seroepidemiology","display_name":"seroepidemiology","score":0.8920000195503235},{"id":"https://openalex.org/keywords/resource-limited-settings","display_name":"resource-limited settings","score":0.7559999823570251},{"id":"https://openalex.org/keywords/continuous-readout","display_name":"continuous readout","score":0.5550000071525574}],"concepts":[{"id":"https://openalex.org/C2781065037","wikidata":"https://www.wikidata.org/wiki/Q150839","display_name":"Salmonella","level":3,"score":0.7594649791717529},{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.6869086623191833},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6819355487823486},{"id":"https://openalex.org/C2992956773","wikidata":"https://www.wikidata.org/wiki/Q21600865","display_name":"Salmonella enteritidis","level":4,"score":0.6311920881271362},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5690204501152039},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5343023538589478},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.44669246673583984},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.400973379611969},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3429907262325287},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3414246737957001},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.20159375667572021},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/biotech12030054","doi":"https://doi.org/10.3390/biotech12030054","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biotech12030054","pdf_url":"https://www.mdpi.com/2673-6284/12/3/54/pdf?version=1691746860","source":{"id":"https://openalex.org/S4210174294","display_name":"BioTech","issn_l":"2673-6284","issn":["2673-6284"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioTech","raw_type":"journal-article"},{"id":"pmid:37606441","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37606441","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biotech (Basel (Switzerland))","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10443281","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10443281","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10443281/pdf/biotech-12-00054.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioTech (Basel)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:9ea7cd68a350402596506a1f479624e5","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/9ea7cd68a350402596506a1f479624e5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BioTech, Vol 12, Iss 3, p 54 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/biotech12030054","doi":"https://doi.org/10.3390/biotech12030054","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biotech12030054","pdf_url":"https://www.mdpi.com/2673-6284/12/3/54/pdf?version=1691746860","source":{"id":"https://openalex.org/S4210174294","display_name":"BioTech","issn_l":"2673-6284","issn":["2673-6284"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioTech","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.75}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1853368883","display_name":null,"funder_award_id":"NIHR300039","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G923077929","display_name":"Advancing a GMMA-based vaccine against invasive non-typhoidal salmonellosis through Phase 1 trial in Europe and sub-Saharan Africa","funder_award_id":"815439","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320310371","display_name":"University of Otago","ror":"https://ror.org/01jmxt844"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320313975","display_name":"Universit\u00e0 degli Studi di Siena","ror":"https://ror.org/01tevnk56"},{"id":"https://openalex.org/F4320318129","display_name":"Instituut voor Tropische Geneeskunde","ror":"https://ror.org/03xq4x896"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320290","display_name":"University of Oxford","ror":"https://ror.org/052gg0110"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320327422","display_name":"Kwame Nkrumah University of Science and Technology","ror":"https://ror.org/00cb23x68"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4385754635.pdf","grobid_xml":"https://content.openalex.org/works/W4385754635.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1844778439","https://openalex.org/W1994719394","https://openalex.org/W1995386819","https://openalex.org/W2087666396","https://openalex.org/W2111790541","https://openalex.org/W2152972548","https://openalex.org/W2165769722","https://openalex.org/W2181314555","https://openalex.org/W2328020511","https://openalex.org/W2328238768","https://openalex.org/W2562954821","https://openalex.org/W2604931152","https://openalex.org/W2732320847","https://openalex.org/W2735017993","https://openalex.org/W2776594371","https://openalex.org/W2894407277","https://openalex.org/W2921255922","https://openalex.org/W2975535544","https://openalex.org/W2996612787","https://openalex.org/W3038741933","https://openalex.org/W3162044619","https://openalex.org/W3169792407","https://openalex.org/W3180544240","https://openalex.org/W3191286509","https://openalex.org/W3194458127","https://openalex.org/W4312194776","https://openalex.org/W4321003734","https://openalex.org/W4379229423"],"related_works":["https://openalex.org/W1552738310","https://openalex.org/W3156743912","https://openalex.org/W2108467075","https://openalex.org/W2058063732","https://openalex.org/W2052529558","https://openalex.org/W2080103473","https://openalex.org/W2173114650","https://openalex.org/W3195263356","https://openalex.org/W2736028114","https://openalex.org/W2505053946"],"abstract_inverted_index":{"Nontyphoidal":[0],"Salmonella":[1,176,179],"(NTS)":[2],"is":[3,40,68,159],"a":[4,81,91],"leading":[5],"cause":[6],"of":[7,29,35,46,51,64,70,80,94,110,116,132,140,173],"morbidity":[8],"and":[9,19,21,48,56,90,112,122,129,135,148,178,190],"mortality":[10],"caused":[11],"by":[12],"enteric":[13],"pathogens":[14],"worldwide":[15],"in":[16,32,182],"both":[17,185],"children":[18],"adults,":[20],"vaccines":[22],"are":[23],"not":[24],"yet":[25],"available.":[26],"The":[27,114],"measurement":[28],"antigen-specific":[30],"antibodies":[31,174],"the":[33,44,49,62,78,117,130,138,157],"sera":[34],"vaccinated":[36],"or":[37],"convalescent":[38],"individuals":[39],"crucial":[41],"to":[42,60,150,168],"understand":[43],"incidence":[45],"disease":[47,158],"immunogenicity":[50],"vaccine":[52,187],"candidates.":[53],"A":[54],"solid":[55],"standardized":[57,92],"assay":[58,85],"used":[59,170],"determine":[61],"level":[63],"specific":[65],"anti-antigens":[66],"IgG":[67],"therefore":[69],"paramount":[71],"importance.":[72],"In":[73],"this":[74],"work,":[75],"we":[76],"presented":[77],"characterization":[79],"customized":[82],"enzyme-linked":[83],"immunosorbent":[84],"(ELISA)":[86],"with":[87,125],"continuous":[88],"readouts":[89],"definition":[93],"EU/mL.":[95],"We":[96],"assessed":[97],"various":[98],"performance":[99],"parameters:":[100],"standard":[101],"curve":[102],"accuracy,":[103],"dilutional":[104],"linearity,":[105],"intermediate":[106],"precision,":[107],"specificity,":[108],"limits":[109],"blanks,":[111],"quantification.":[113],"simplicity":[115],"assay,":[118],"its":[119,126],"high":[120,141],"sensitivity":[121],"specificity":[123],"coupled":[124],"low":[127],"cost":[128],"use":[131],"basic":[133],"consumables":[134],"instruments":[136],"without":[137],"need":[139],"automation":[142],"makes":[143],"it":[144],"suitable":[145],"for":[146,166,171,186],"transfer":[147],"application":[149],"different":[151],"laboratories,":[152],"including":[153],"resource-limiting":[154],"settings":[155],"where":[156],"endemic.":[160],"This":[161],"ELISA":[162],"is,":[163],"therefore,":[164],"fit":[165],"purpose":[167],"be":[169],"quantification":[172],"against":[175],"Typhimurium":[177],"Enteritidis":[180],"O-antigens":[181],"human":[183],"samples,":[184],"clinical":[188],"trials":[189],"large":[191],"sero-epidemiological":[192],"studies.":[193]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":4}],"updated_date":"2026-10-15T10:00:46.086208","created_date":"2025-10-10T00:00:00"}