{"id":"https://openalex.org/W4385723098","doi":"https://doi.org/10.1097/txd.0000000000001524","title":"Donor Origin Neuroendocrine Cancer: A Case Report and Literature Review","display_name":"Donor Origin Neuroendocrine Cancer: A Case Report and Literature Review","publication_year":2023,"publication_date":"2023-08-09","ids":{"openalex":"https://openalex.org/W4385723098","doi":"https://doi.org/10.1097/txd.0000000000001524","pmid":"https://pubmed.ncbi.nlm.nih.gov/37575954"},"language":"en","primary_location":{"id":"doi:10.1097/txd.0000000000001524","doi":"https://doi.org/10.1097/txd.0000000000001524","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1097/txd.0000000000001524","pdf_url":null,"source":{"id":"https://openalex.org/S2764430067","display_name":"Transplantation Direct","issn_l":"2373-8731","issn":["2373-8731"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation Direct","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1097/txd.0000000000001524","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"James E. Brady","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"James E. Brady","raw_affiliation_strings":["Division of General Internal Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General Internal Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092795957","display_name":"Lo Tamburro","orcid":"https://orcid.org/0009-0003-2571-5491","observed_orcids":["https://orcid.org/0009-0003-2571-5491"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lo Tamburro","raw_affiliation_strings":["Department of Pathology, University of Maryland School of Medicine, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Maryland School of Medicine, Baltimore, MD","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039198669","display_name":"Abel G. Joy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abel G. Joy","raw_affiliation_strings":["Division of General Internal Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General Internal Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036438937","display_name":"Richard M. Ugarte","orcid":"https://orcid.org/0000-0002-0561-1455","observed_orcids":["https://orcid.org/0000-0002-0561-1455"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard M. Ugarte","raw_affiliation_strings":["Department of Medicine, Division of Nephrology, University of Maryland, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Nephrology, University of Maryland, Baltimore, MD","institution_ids":["https://openalex.org/I126744593"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I126744593"],"apc_list":{"value":2200,"currency":"USD","value_usd":2200},"apc_paid":{"value":2200,"currency":"USD","value_usd":2200},"fwci":0.1664,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.49848591,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"9","issue":"9","first_page":"e1524","last_page":"e1524"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.33009999990463257,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.33009999990463257,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11163","display_name":"Organ Donation and Transplantation","score":0.2551000118255615,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.023900000378489494,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroendocrine-cancer","display_name":"neuroendocrine cancer","score":0.8130000233650208},{"id":"https://openalex.org/keywords/solid-organ-transplantation","display_name":"solid organ transplantation","score":0.7210000157356262},{"id":"https://openalex.org/keywords/simultaneous-pancreas-kidney-transplantation","display_name":"simultaneous pancreas-kidney transplantation","score":0.7699999809265137},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.7770000100135803},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.675000011920929},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.6510000228881836},{"id":"https://openalex.org/keywords/donor-derived-malignancy","display_name":"donor-derived malignancy","score":0.38199999928474426},{"id":"https://openalex.org/keywords/high-grade-neuroendocrine-carcinoma","display_name":"high-grade neuroendocrine carcinoma","score":0.5239999890327454},{"id":"https://openalex.org/keywords/tacrolimus","display_name":"tacrolimus","score":0.421999990940094},{"id":"https://openalex.org/keywords/azathioprine","display_name":"azathioprine","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9118783473968506},{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.7017208337783813},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.6771413087844849},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6371500492095947},{"id":"https://openalex.org/C168444539","wikidata":"https://www.wikidata.org/wiki/Q105196","display_name":"Organ transplantation","level":3,"score":0.530419647693634},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.47295448184013367},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.44281768798828125},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.42214563488960266},{"id":"https://openalex.org/C3018513187","wikidata":"https://www.wikidata.org/wiki/Q712378","display_name":"Solid organ","level":4,"score":0.41894227266311646},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3915904462337494},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3683125376701355},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.33774814009666443},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.08455142378807068}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1097/txd.0000000000001524","doi":"https://doi.org/10.1097/txd.0000000000001524","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1097/txd.0000000000001524","pdf_url":null,"source":{"id":"https://openalex.org/S2764430067","display_name":"Transplantation Direct","issn_l":"2373-8731","issn":["2373-8731"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation Direct","raw_type":"journal-article"},{"id":"pmid:37575954","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37575954","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation direct","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10414708","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10414708","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10414708/pdf/txd-9-e1524.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Transplant Direct","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:5d5bfd09e73747808d6b79a8d56f409e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/5d5bfd09e73747808d6b79a8d56f409e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Transplantation Direct, Vol 9, Iss 9, p e1524 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1097/txd.0000000000001524","doi":"https://doi.org/10.1097/txd.0000000000001524","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1097/txd.0000000000001524","pdf_url":null,"source":{"id":"https://openalex.org/S2764430067","display_name":"Transplantation Direct","issn_l":"2373-8731","issn":["2373-8731"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation Direct","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.75}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W99403674","https://openalex.org/W1486381680","https://openalex.org/W1510673877","https://openalex.org/W1964106115","https://openalex.org/W1978503051","https://openalex.org/W2031576581","https://openalex.org/W2045323064","https://openalex.org/W2404474185","https://openalex.org/W2922871207","https://openalex.org/W3047360845","https://openalex.org/W3114309033","https://openalex.org/W4285740663"],"related_works":["https://openalex.org/W1980045831","https://openalex.org/W2889471847","https://openalex.org/W288055997","https://openalex.org/W2084795750","https://openalex.org/W2890967461","https://openalex.org/W4248977302","https://openalex.org/W1988995773","https://openalex.org/W3081811132","https://openalex.org/W2901037595","https://openalex.org/W4240283622"],"abstract_inverted_index":{"Solid":[0,90],"organ":[1,29,91,129,875,981,1015,1364,1480,1504,1609,1624],"transplantation":[2,92,119,352,1171,1382,1610],"has":[3,1467],"been":[4,542,1168,1329],"instrumental":[5],"in":[6,64,318,376,387,403,468,475,494,546,599,698,724,739,763,842,871,884,943,956,992,1011,1031,1067,1089,1100,1137,1192,1308,1345,1352,1499,1518,1558,1590],"improving":[7],"the":[8,60,65,95,113,116,147,209,242,254,265,270,277,286,299,322,340,343,366,423,450,454,469,476,495,529,547,566,569,574,577,583,589,614,619,626,656,690,699,725,740,764,769,773,776,785,821,834,878,918,921,975,984,1020,1043,1048,1070,1090,1101,1189,1193,1212,1254,1258,1272,1286,1323,1341,1353,1416,1437,1455,1460,1465,1474,1479,1486,1492,1502,1512,1552,1571,1578,1621,1648,1653],"quality":[9],"of":[10,12,24,27,36,40,59,97,118,135,149,167,202,206,211,230,253,321,330,335,374,389,411,422,449,552,616,655,675,754,768,775,797,882,901,923,940,1045,1050,1064,1073,1103,1130,1148,1177,1203,1224,1234,1253,1271,1291,1317,1343,1360,1371,1395,1418,1429,1439,1447,1471,1476,1478,1491,1501,1516,1543,1549,1554,1562,1580,1615,1623],"life":[11],"patients":[13,872,885,958,977,1012,1400,1591],"with":[14,42,52,138,163,227,260,273,426,437,595,660,719,729,745,772,839,873,886,1013,1042,1174,1207,1222,1295,1314,1331,1373,1399,1426,1473,1522,1536,1541,1592,1611,1639],"end-organ":[15],"damage,":[16],"but":[17,365,576,635,1557],"this":[18,150,1281],"does":[19,1629],"not":[20,346,519,580,643,968],"come":[21],"risk-free.1":[22],"Because":[23,1464],"immunosuppression,":[25],"recipients":[26,945,1256,1347,1521,1535],"solid":[28,128,874,980,1014,1363],"transplants":[30,876],"are":[31,104,877,903,912,927,972,1093],"at":[32,115,208,610,628,920,1119,1377,1443],"an":[33,83,401,680,1162],"elevated":[34,341,609],"risk":[35,96,939,1049,1202,1233,1342,1394,1409,1417,1438,1614],"developing":[37,98,941],"certain":[38],"types":[39],"cancer,":[41],"some":[43],"reports":[44,1428],"documenting":[45],"as":[46,48,471,473,782,784,914,1261,1389,1421,1423,1505,1507],"high":[47,438,530,1230,1422],"4":[49,953],"times":[50,954],"compared":[51,1425],"their":[53,993,1262],"nontransplant":[54],"counterparts.2":[55],"The":[56,183,291,308,356,381,405,460,499,513,673,789,800,938,1393,1431,1445,1613],"decreased":[57],"efficacy":[58],"immune":[61,84,986,1025,1494,1581],"system":[62,987,1026,1495],"results":[63],"body\u2019s":[66],"inability":[67],"to":[68,86,112,175,194,276,285,371,384,399,557,568,572,582,625,632,645,795,812,829,846,856,895,929,948,964,974,988,1019,1055,1078,1094,1134,1139,1179,1200,1227,1242,1277,1304,1350,1386,1391,1482,1588,1604,1646],"remove":[69,996],"abnormal":[70],"and":[71,77,142,145,180,198,219,256,264,282,298,353,363,414,478,515,531,588,597,641,652,694,756,766,778,850,859,863,892,907,952,967,971,995,1047,1083,1126,1150,1198,1245,1311,1383,1459,1530,1583,1634,1643],"cancerous":[72,990],"cells":[73,685,991],"before":[74,998],"they":[75,1283],"propagate":[76],"form":[78],"a":[79,133,136,160,164,216,223,228,245,304,319,408,418,427,430,508,523,543,558,761,840,1023,1028,1036,1061,1096,1146,1175,1208,1219,1229,1249,1269,1332,1450,1547,1559,1599,1627,1636],"tumor":[80,419,455,606,1275],"or":[81,120,1152,1231,1334],"mount":[82],"response":[85,794,1540],"known":[87],"carcinogenic":[88],"viruses.2":[89],"also":[93,1008,1267],"carries":[94],"donor-origin":[99],"cancers":[100,905,909,915,931,942,966,1003],"(DOCs).":[101],"These":[102,961,1236,1585],"malignancies":[103,1124],"rare":[105,1600],"occurrences":[106],"that":[107,416,453,538,550,932,1022,1128,1285,1322,1358,1415,1436,1570,1602],"can":[108],"either":[109],"be":[110,930,949,1079,1387,1483,1605,1618],"transmitted":[111],"recipient":[114,919,1493],"time":[117,126,615,922],"develop":[121,195],"from":[122,222,235,369,935,1081,1172,1205,1348,1381],"donor":[123,226,243,292,424,458,786,936,1164,1183,1190,1468,1503,1509],"tissue":[124,1488],"over":[125],"after":[127,315,326,351,866,979,1527],"transplantation.1,3,4":[130],"We":[131],"present":[132],"case":[134],"patient":[137,158,184,300,309,344,367,382,406,570,578,590,801],"both":[139,528],"high-grade":[140],"DOC":[141,144,902,1204,1388,1448,1466,1576,1597,1616,1628],"low-grade":[143],"review":[146,1270,1278,1561],"management":[148,1446,1553,1574,1631],"patient\u2019s":[151,620,790,835],"complex":[152,1633],"malignancy":[153,545,732,1220,1296,1305],"care.":[154],"CASE":[155],"DESCRIPTION":[156],"Our":[157],"was":[159,185,259,267,359,397,456,551,571,586,591,608,639,802,854,1298,1312,1397,1420,1441,1577],"69-y-old":[161],"man":[162],"medical":[165,1456,1641],"history":[166,229,1059,1076,1176],"end-stage":[168],"renal":[169,189,348,637,647,851,1563],"disease":[170,781,1524],"on":[171,593,716,804,1113],"peritoneal":[172],"dialysis":[173],"secondary":[174],"long-standing":[176],"type":[177],"1":[178],"diabetes":[179,197],"resultant":[181],"nephrosclerosis.":[182],"undergoing":[186,1528],"evaluation":[187],"for":[188,306,689,806,815,820,1123,1575,1652],"transplant":[190,221,944,1274,1346,1457,1462,1520,1534,1564,1644],"when":[191,395,1607],"he":[192,214,396,630],"started":[193,592,803],"brittle":[196],"had":[199,244,294,303,310,623,1218],"numerous":[200],"episodes":[201],"hypoglycemia.":[203],"In":[204,1280],"February":[205],"2017":[207],"age":[210],"64":[212],"y,":[213,1403],"underwent":[215,407],"simultaneous":[217],"pancreas":[218,266,293,425,548],"kidney":[220,323,1533],"38-y-old":[224],"deceased":[225],"uncontrolled":[231],"hypertension":[232],"who":[233],"passed":[234,860],"catastrophic":[236,1325],"intracranial":[237],"hemorrhage":[238],"(ICH).":[239],"Before":[240,826],"donation,":[241],"grossly":[246],"normal":[247],"noncontrast":[248],"computed":[249,749],"tomography":[250,487],"(CT)":[251],"scan":[252,410,464,714,718,1156],"abdomen":[255,413],"pelvis.":[257],"Induction":[258],"rabbit":[261],"antithymocyte":[262],"globulin,":[263],"transplanted":[268,916],"into":[269,917],"right":[271,278,287,701],"pelvis":[272,415],"venous":[274],"anastomosis":[275,284],"common":[279,1288,1573],"iliac":[280,289],"vein":[281],"arterial":[283],"external":[288],"artery.":[290],"immediate":[295],"graft":[296,390],"function,":[297],"no":[301],"longer":[302],"need":[305,644],"insulin.":[307],"higher":[311,889,955,1010],"than":[312,890],"expected":[313],"creatinine":[314,354],"transplantation,":[316,327,924,982,1016,1052],"resulting":[317],"biopsy":[320,428,451,659],"2":[324,880,951],"mo":[325,865,1380],"showing":[328,664],"evidence":[329,334],"interstitial":[331],"fibrosis":[332],"without":[333,959,1404],"acute":[336],"allograft":[337,549],"rejection.":[338],"Despite":[339],"creatinine,":[342],"did":[345,642,1434],"require":[347,1109],"replacement":[349,648],"therapy":[350,796,819],"improved.":[355],"immunosuppression":[357,976,1472],"plan":[358],"initially":[360],"tacrolimus,":[361],"mycophenolate,":[362],"prednisone,":[364],"transitioned":[368],"mycophenolate":[370],"azathioprine":[372],"because":[373],"diarrhea":[375],"2020,":[377],"which":[378,629],"resolved":[379],"symptoms.":[380],"continued":[383],"do":[385,1525],"well":[386,472,783,1506,1526],"terms":[388],"function":[391,622,638],"until":[392,555],"early":[393],"2022,":[394],"noted":[398,671,703,738],"have":[400,541,1167,1228,1328],"increase":[402],"lipase.":[404],"CT":[409,463,488,717,1155,1159],"his":[412,636],"revealed":[417,452],"replacing":[420],"most":[421,1074,1287,1572],"diagnosing":[429],"poorly":[431,524,561],"differentiated":[432,525,562,731],"neuroendocrine":[433,682,691],"small":[434,676],"cell":[435],"carcinoma":[436],"(85%\u201390%)":[439],"Ki-67":[440],"proliferation":[441],"index":[442],"(Figure":[443,497,511],"1).":[444],"Short":[445],"tandem":[446],"repeat":[447],"analysis":[448],"82%":[457],"tissue.":[459,1514],"whole":[461],"body":[462,481],"showed":[465,490,502,760,793],"innumerable":[466,741],"lesions":[467,474,493,771],"liver":[470,516,779,1519],"lungs":[477],"bones.":[479],"Whole":[480],"Gallium":[482,822],"68":[483,823],"DOTA-TATE":[484,491,505,520,533,722,736],"positron":[485],"emission":[486],"scanning":[489],"avid":[492,824],"bone":[496,742,777],"2).":[498,512],"pancreatic":[500,621,662,726,787],"mass":[501,727],"homogenous":[503],"low-level":[504],"activity,":[506],"suggesting":[507,522],"moderate":[509],"differentiation":[510],"lung":[514],"masses":[517],"were":[518,536,1367,1384],"avid,":[521],"tumor.":[526,683,1336],"Given":[527,1069,1161,1485],"low":[532],"avidity,":[534],"there":[535,539,1366],"concerns":[537],"may":[540,1327],"smoldering":[544],"subclinical":[553],"importance":[554],"conversion":[556],"more":[559,1593],"aggressive,":[560],"malignancy.":[563,747,1235,1250],"Following":[564],"staging,":[565],"recommendation":[567],"explant":[573],"pancreas,":[575],"would":[579,1497],"consent":[581],"surgery.":[584],"Immunosuppression":[585],"decreased,":[587],"chemotherapy":[594],"carboplatin":[596,755],"etoposide":[598],"April":[600],"2022.":[601],"Patient\u2019s":[602],"initial":[603],"chromogranin":[604,791,843],"A":[605,792,844,1057],"marker":[607],"700":[611],"ng/mL.":[612,799],"Around":[613],"starting":[617],"chemotherapy,":[618],"declined":[624],"point":[627],"needed":[631],"restart":[633],"insulin,":[634],"stable":[640],"resume":[646],"therapy.FIGURE":[649],"1.:":[650],"Hematoxylin":[651],"Eosin":[653],"stain":[654,686],"needle":[657],"core":[658],"exocrine":[661],"lobule":[663],"partial":[665],"atrophy.":[666],"An":[667],"endocrine":[668,707],"islet":[669],"is":[670,946,1035,1060,1546,1598,1632],"(arrow).":[672,733],"aggregates":[674],"\u201cblue":[677],"cells\u201d":[678],"represents":[679],"infiltrative":[681],"Tumor":[684],"strongly":[687],"positive":[688],"markers":[692],"INSM1":[693],"CD56.":[695],"Weaker":[696],"staining":[697],"lower":[700,1442],"image,":[702],"by":[704,1005],"arrow,":[705],"demonstrates":[706],"islet.":[708],"Bar:":[709],"200":[710],"\u00b5m.FIGURE":[711],"2.:":[712],"PET":[713],"superimposed":[715],"(A)":[720],"mild":[721],"uptake":[723,737],"consistent":[728,744],"moderately":[730],"B,":[734],"High":[735],"lesions,":[743],"well-differentiated":[746],"CT,":[748],"tomography.After":[750],"completing":[751],"6":[752],"cycles":[753],"etoposide,":[757],"restaging":[758],"imaging":[759,1111],"decrease":[762],"size":[765],"number":[767,879],"pulmonary":[770],"persistence":[774],"metastatic":[780,1335],"mass.":[788],"429":[798],"lanreotide":[805],"somatostatin":[807],"suppression":[808,1582],"while":[809],"being":[810,827],"referred":[811],"nuclear":[813],"medicine":[814,1645],"Lutetium":[816,831],"177":[817,832],"radioactive":[818],"lesions.":[825],"able":[828],"schedule":[830],"treatment,":[833],"overall":[836,1163],"health":[837],"deteriorated":[838],"spike":[841],"level":[845],"16":[847],"000":[848],"ng/mL":[849],"failure.":[852],"He":[853],"admitted":[855],"home":[857],"hospice":[858],"5":[861,1379],"y":[862],"8":[864,1247,1255],"transplantation.":[867,960,1625],"DISCUSSION":[868],"Cancer-related":[869],"deaths":[870],"cause":[881,1290],"death":[883,1293,1302],"functioning":[887],"grafts,":[888],"infections":[891],"second":[893],"only":[894,1246,1368],"cardiovascular":[896],"disease.4":[897],"Two":[898],"large":[899],"subclassifications":[900],"donor-transmitted":[904],"(DTCs)":[906],"donor-derived":[908,1487],"(DDCs).":[910],"DTCs":[911],"defined":[913],"whereas":[925,1532],"DDCs":[926],"felt":[928,1385],"arise":[933],"later":[934],"tissue.5":[937],"estimated":[947],"between":[950,1039,1196],"comparable":[957],"risks":[962,1040],"refer":[963],"all":[965,1508],"just":[969],"DOCs":[970,1517,1537],"related":[973],"receive":[978],"limiting":[983],"recipient\u2019s":[985],"find":[989,1435],"infancy":[994],"them":[997,1225],"tumors":[999],"develop.1-4,5":[1000],"Studies":[1001],"suggest":[1002],"caused":[1004],"viral":[1006],"illnesses":[1007],"occur":[1009],"lending":[1017],"credence":[1018],"idea":[1021],"dampened":[1024],"plays":[1027],"significant":[1029,1408],"role":[1030],"carcinogenesis.2":[1032],"Donor":[1033],"selection":[1034],"balancing":[1037],"act":[1038],"associated":[1041,1294,1313,1330,1398],"transmission":[1044,1297],"diseases":[1046],"delayed":[1051],"possibly":[1053],"leading":[1054],"death.":[1056],"thorough":[1058],"crucial":[1062],"part":[1063],"cancer":[1065,1086,1178,1209,1260],"screening":[1066,1102,1122],"donors.":[1068,1105],"clinical":[1071],"condition":[1072],"donors,":[1075],"needs":[1077,1481,1603,1635],"obtained":[1080],"family":[1082],"caregivers.":[1084],"Current":[1085],"surveillance":[1087],"guidelines":[1088,1125,1166],"United":[1091,1194,1354],"States":[1092],"perform":[1095,1135],"chest":[1097,1158],"X-ray":[1098],"(CXR)":[1099],"potential":[1104],"Different":[1106],"regions":[1107],"could":[1108],"further":[1110,1182],"based":[1112],"history.":[1114,1210],"Chotkan":[1115],"et":[1116,1186,1265,1338,1567],"al":[1117,1187,1266,1339,1568],"looked":[1118],"global":[1120],"radiologic":[1121],"found":[1127,1284,1357,1414,1569],"41%":[1129],"32":[1131],"countries":[1132,1144],"responded":[1133],"CXR":[1136,1149],"addition":[1138],"abdominal":[1140,1154],"ultrasound.":[1141],"Eleven":[1142],"respondent":[1143],"performed":[1145,1268],"combination":[1147],"enhanced":[1151],"unenhanced":[1153],"\u00b1":[1157],"scan.6":[1160],"shortage,":[1165],"developed":[1169,1248,1257],"regarding":[1170,1551],"donors":[1173,1206,1217,1238,1310],"help":[1180],"mitigate":[1181],"shortage.":[1184],"Desai":[1185,1337],"reviewed":[1188,1340],"registry":[1191,1276],"Kingdom":[1195],"1990":[1197],"2008":[1199],"evaluate":[1201],"Of":[1211],"17":[1213],"639":[1214],"donations,":[1215],"202":[1216],"history,":[1221],"61":[1223,1237],"deemed":[1226],"unacceptable":[1232],"donated":[1239],"140":[1240],"organs":[1241],"133":[1243],"recipients,":[1244,1565],"However,":[1251],"none":[1252],"same":[1259,1432],"donor.7":[1263],"Buell":[1264],"international":[1273],"DDC.":[1279],"series,":[1282],"misdiagnosed":[1289],"brain":[1292,1301],"ICH.":[1299],"Misdiagnosed":[1300],"attributed":[1303],"postmortem":[1306],"occurred":[1307],"42":[1309],"31":[1315],"cases":[1316],"DDC":[1318,1440],"(74%).3":[1319],"This":[1320,1412],"suggests":[1321],"underlying":[1324],"ICH":[1326],"primary":[1333],"DTC":[1344,1396,1419],"2001":[1349],"2010":[1351],"Kingdom.":[1355],"They":[1356],"out":[1359],"30":[1361],"765":[1362],"transplants,":[1365],"18":[1369],"incidences":[1370,1375],"DDCs,":[1372],"3":[1374],"occurring":[1376],"least":[1378],"opposed":[1390],"DTC.":[1392],"aged":[1401],">45":[1402],"any":[1405],"other":[1406],"statistically":[1407],"factor":[1410],"identified.":[1411],"report":[1413,1433],"0.06%,":[1424],"earlier":[1427],"0.01%.":[1430],"0.01%.1":[1444],"requires":[1449],"multidisciplinary":[1451,1637],"approach":[1452,1638],"involving":[1453],"oncology,":[1454,1642],"team,":[1458],"surgical":[1461],"team.":[1463],"tissue,":[1469,1510],"removal":[1470],"possibility":[1475],"explantation":[1477,1529],"considered.8":[1484],"malignancy,":[1489],"reconstitution":[1490],"theoretically":[1496],"result":[1498],"rejection":[1500],"including":[1511],"malignant":[1513],"Reports":[1515],"localized":[1523,1594],"retransplantation,":[1531],"show":[1538],"good":[1539],"cessation":[1542],"immunosuppression.5,9,10":[1544],"There":[1545],"paucity":[1548],"data":[1550],"SPK":[1555],"DOC,":[1556],"systematic":[1560],"Xiao":[1566],"withdrawal":[1579],"nephrectomy.":[1584],"strategies":[1586],"appeared":[1587],"work":[1589],"diseases.11":[1595],"Ultimately,":[1596],"phenomenon":[1601],"considered":[1606],"discussing":[1608],"patients.":[1612],"must":[1617],"weighed":[1619],"against":[1620],"benefits":[1622],"If":[1626],"occur,":[1630],"surgery,":[1640],"provide":[1647],"best":[1649],"treatment":[1650],"option":[1651],"patient.":[1654]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}