{"id":"https://openalex.org/W4385542265","doi":"https://doi.org/10.3390/jcm12155094","title":"Sex-Based Differences in Clinical Characteristics and Outcomes among Patients with Peripheral Artery Disease: A Retrospective Analysis","display_name":"Sex-Based Differences in Clinical Characteristics and Outcomes among Patients with Peripheral Artery Disease: A Retrospective Analysis","publication_year":2023,"publication_date":"2023-08-03","ids":{"openalex":"https://openalex.org/W4385542265","doi":"https://doi.org/10.3390/jcm12155094","pmid":"https://pubmed.ncbi.nlm.nih.gov/37568498","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10420161"},"language":"en","primary_location":{"id":"doi:10.3390/jcm12155094","doi":"https://doi.org/10.3390/jcm12155094","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm12155094","pdf_url":"https://www.mdpi.com/2077-0383/12/15/5094/pdf?version=1691036822","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2077-0383/12/15/5094/pdf?version=1691036822","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065175132","display_name":"Giuseppe De Matteis","orcid":"https://orcid.org/0000-0003-2982-3951","observed_orcids":["https://orcid.org/0000-0003-2982-3951"]},"institutions":[{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe De Matteis","raw_affiliation_strings":["Fondazione Policlinico Universitario Agostino Gemelli IRCCS","Department of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","institution_ids":["https://openalex.org/I2802557943"]},{"raw_affiliation_string":"Department of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064352327","display_name":"Federico Biscetti","orcid":"https://orcid.org/0000-0001-7449-657X","observed_orcids":["https://orcid.org/0000-0001-7449-657X"]},"institutions":[{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federico Biscetti","raw_affiliation_strings":["Fondazione Policlinico Universitario Agostino Gemelli IRCCS","Cardiovascular Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","institution_ids":["https://openalex.org/I2802557943"]},{"raw_affiliation_string":"Cardiovascular Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026954697","display_name":"Davide Antonio Della Polla","orcid":"https://orcid.org/0000-0002-6076-9538","observed_orcids":["https://orcid.org/0000-0002-6076-9538"]},"institutions":[{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Davide Antonio Della Polla","raw_affiliation_strings":["Fondazione Policlinico Universitario Agostino Gemelli IRCCS","Emergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","institution_ids":["https://openalex.org/I2802557943"]},{"raw_affiliation_string":"Emergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091017678","display_name":"Amato Serra","orcid":"https://orcid.org/0000-0002-0191-6016","observed_orcids":["https://orcid.org/0000-0002-0191-6016"]},"institutions":[{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Amato Serra","raw_affiliation_strings":["Fondazione Policlinico Universitario Agostino Gemelli IRCCS","Department of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy"],"raw_orcid":"https://orcid.org/0000-0002-0191-6016","affiliations":[{"raw_affiliation_string":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","institution_ids":["https://openalex.org/I2802557943"]},{"raw_affiliation_string":"Department of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013592431","display_name":"Maria Livia Burzo","orcid":"https://orcid.org/0000-0002-5705-6262","observed_orcids":["https://orcid.org/0000-0002-5705-6262"]},"institutions":[{"id":"https://openalex.org/I4210107523","display_name":"Ospedale di Santo Spirito","ror":"https://ror.org/01jj26143","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210107523"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Livia Burzo","raw_affiliation_strings":["Santo Spirito Hospital: Ospedale Santo Spirito","Department of Internal Medicine, Ospedale Santo Spirito in Sassia, 00193 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Santo Spirito Hospital: Ospedale Santo Spirito","institution_ids":["https://openalex.org/I4210107523"]},{"raw_affiliation_string":"Department of Internal Medicine, Ospedale Santo Spirito in Sassia, 00193 Rome, Italy","institution_ids":["https://openalex.org/I4210107523"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072152506","display_name":"Mariella Fuorlo","orcid":"https://orcid.org/0000-0003-2718-9360","observed_orcids":["https://orcid.org/0000-0003-2718-9360"]},"institutions":[{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mariella Fuorlo","raw_affiliation_strings":["Fondazione Policlinico Universitario Agostino Gemelli IRCCS","Emergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","institution_ids":["https://openalex.org/I2802557943"]},{"raw_affiliation_string":"Emergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058039168","display_name":"Maria Anna Nicolazzi","orcid":"https://orcid.org/0000-0002-6900-1963","observed_orcids":["https://orcid.org/0000-0002-6900-1963"]},"institutions":[{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Anna Nicolazzi","raw_affiliation_strings":["Fondazione Policlinico Universitario Agostino Gemelli IRCCS","Cardiovascular Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","institution_ids":["https://openalex.org/I2802557943"]},{"raw_affiliation_string":"Cardiovascular Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041978159","display_name":"Angela Novelli","orcid":"https://orcid.org/0009-0000-9202-6512","observed_orcids":["https://orcid.org/0009-0000-9202-6512"]},"institutions":[{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Angela Novelli","raw_affiliation_strings":["Fondazione Policlinico Universitario Agostino Gemelli IRCCS","Emergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","institution_ids":["https://openalex.org/I2802557943"]},{"raw_affiliation_string":"Emergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090725835","display_name":"Angelo Santoliquido","orcid":"https://orcid.org/0000-0003-1539-4017","observed_orcids":["https://orcid.org/0000-0003-1539-4017"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Angelo Santoliquido","raw_affiliation_strings":["Universit\u00e0 Cattolica del Sacro Cuore: Universita Cattolica del Sacro Cuore","Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore: Universita Cattolica del Sacro Cuore","institution_ids":["https://openalex.org/I103320735"]},{"raw_affiliation_string":"Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109358672","display_name":"Giovanni Gambassi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanni Gambassi","raw_affiliation_strings":["Universit\u00e0 Cattolica del Sacro Cuore: Universita Cattolica del Sacro Cuore","Department of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore: Universita Cattolica del Sacro Cuore","institution_ids":["https://openalex.org/I103320735"]},{"raw_affiliation_string":"Department of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031340334","display_name":"Antonio Gasbarrini","orcid":"https://orcid.org/0000-0002-6230-1779","observed_orcids":["https://orcid.org/0000-0002-6230-1779","https://orcid.org/0000-0003-4863-6924"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Gasbarrini","raw_affiliation_strings":["Universit\u00e0 Cattolica del Sacro Cuore: Universita Cattolica del Sacro Cuore","Department of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore: Universita Cattolica del Sacro Cuore","institution_ids":["https://openalex.org/I103320735"]},{"raw_affiliation_string":"Department of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030125369","display_name":"Andrea Flex","orcid":"https://orcid.org/0000-0003-2664-4165","observed_orcids":["https://orcid.org/0000-0003-2664-4165"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Flex","raw_affiliation_strings":["Universit\u00e0 Cattolica del Sacro Cuore: Universita Cattolica del Sacro Cuore","Cardiovascular Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore: Universita Cattolica del Sacro Cuore","institution_ids":["https://openalex.org/I103320735"]},{"raw_affiliation_string":"Cardiovascular Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083163170","display_name":"Francesco Franceschi","orcid":"https://orcid.org/0000-0002-9090-8244","observed_orcids":["https://orcid.org/0000-0002-9090-8244","https://orcid.org/0000-0001-6266-445X"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesco Franceschi","raw_affiliation_strings":["Universit\u00e0 Cattolica del Sacro Cuore: Universita Cattolica del Sacro Cuore","Emergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e0 Cattolica del Sacro Cuore: Universita Cattolica del Sacro Cuore","institution_ids":["https://openalex.org/I103320735"]},{"raw_affiliation_string":"Emergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060283382","display_name":"Marcello Covino","orcid":"https://orcid.org/0000-0002-6709-2531","observed_orcids":["https://orcid.org/0000-0002-6709-2531"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marcello Covino","raw_affiliation_strings":["Fondazione Policlinico Universitario Agostino Gemelli IRCCS","Emergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","institution_ids":["https://openalex.org/I2802557943"]},{"raw_affiliation_string":"Emergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy","institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"]},{"raw_affiliation_string":"Faculty of Medicine and Surgery, Rome Campus, Universit\u00e0 Cattolica del Sacro Cuore, 20123 Rome, Italy","institution_ids":["https://openalex.org/I103320735"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5026954697"],"corresponding_institution_ids":["https://openalex.org/I2802557943","https://openalex.org/I4210153126"],"apc_list":{"value":2600,"currency":"CHF","value_usd":2892},"apc_paid":{"value":2600,"currency":"CHF","value_usd":2892},"fwci":2.9911,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.9156064,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"12","issue":"15","first_page":"5094","last_page":"5094"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10926","display_name":"Peripheral Artery Disease Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10926","display_name":"Peripheral Artery Disease Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13252","display_name":"Sex and Gender in Healthcare","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11554","display_name":"Vascular Procedures and Complications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peripheral-arterial-disease","display_name":"peripheral arterial disease","score":0.8539999723434448},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.9950000047683716},{"id":"https://openalex.org/keywords/major-adverse-cardiovascular-events","display_name":"major adverse cardiovascular events","score":0.8799999952316284},{"id":"https://openalex.org/keywords/major-adverse-limb-events","display_name":"major adverse limb events","score":0.9990000128746033},{"id":"https://openalex.org/keywords/lower-extremity-amputation","display_name":"lower limb amputation","score":0.890999972820282},{"id":"https://openalex.org/keywords/revascularization","display_name":"revascularization","score":0.7630000114440918},{"id":"https://openalex.org/keywords/angioplasty","display_name":"angioplasty","score":0.972000002861023},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.8069999814033508},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.9829999804496765},{"id":"https://openalex.org/keywords/emergency-department-admission","display_name":"emergency department admission","score":0.6470000147819519},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9851480722427368},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.6162547469139099},{"id":"https://openalex.org/C3018348675","wikidata":"https://www.wikidata.org/wiki/Q4797557","display_name":"Arterial disease","level":3,"score":0.6073245406150818},{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.554023265838623},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5498072504997253},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44238972663879395},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.26202282309532166}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/jcm12155094","doi":"https://doi.org/10.3390/jcm12155094","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm12155094","pdf_url":"https://www.mdpi.com/2077-0383/12/15/5094/pdf?version=1691036822","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-2895560/v1","doi":"https://doi.org/10.21203/rs.3.rs-2895560/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-2895560/v1","pdf_url":"https://www.researchsquare.com/article/rs-2895560/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10420161","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10420161","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10420161/pdf/jcm-12-05094.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Med","raw_type":"Text"},{"id":"pmid:37568498","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37568498","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical medicine","raw_type":"Journal Article"},{"id":"pmh:oai:publicatt.unicatt.it:10807/292319","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10807/292319","pdf_url":null,"source":{"id":"https://openalex.org/S4306400564","display_name":"PubliCatt (Universit\u00e0 Cattolica del Sacro Cuore)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3390/jcm12155094","doi":"https://doi.org/10.3390/jcm12155094","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm12155094","pdf_url":"https://www.mdpi.com/2077-0383/12/15/5094/pdf?version=1691036822","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0},{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.7390999794006348}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4385542265.pdf","grobid_xml":"https://content.openalex.org/works/W4385542265.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W2000445173","https://openalex.org/W2060449981","https://openalex.org/W2082793300","https://openalex.org/W2121275621","https://openalex.org/W2140136269","https://openalex.org/W2142118385","https://openalex.org/W2143483143","https://openalex.org/W2148374679","https://openalex.org/W2165859230","https://openalex.org/W2222741751","https://openalex.org/W2238299078","https://openalex.org/W2301244336","https://openalex.org/W2315532081","https://openalex.org/W2367892943","https://openalex.org/W2552730765","https://openalex.org/W2616330098","https://openalex.org/W2776174981","https://openalex.org/W2847830914","https://openalex.org/W2891989699","https://openalex.org/W2911449489","https://openalex.org/W2913509784","https://openalex.org/W2924084968","https://openalex.org/W2948088675","https://openalex.org/W2959853492","https://openalex.org/W2965565030","https://openalex.org/W3005246872","https://openalex.org/W3087861475","https://openalex.org/W3122226502","https://openalex.org/W3122323559","https://openalex.org/W3124873984","https://openalex.org/W3174506987","https://openalex.org/W4210518843","https://openalex.org/W4212804367","https://openalex.org/W4212986363","https://openalex.org/W4213266113","https://openalex.org/W4214502424","https://openalex.org/W4223524036","https://openalex.org/W4281255095","https://openalex.org/W4290631407","https://openalex.org/W4317567557","https://openalex.org/W4322741013","https://openalex.org/W4328053212"],"related_works":["https://openalex.org/W3095659392","https://openalex.org/W2328831628","https://openalex.org/W4241029249","https://openalex.org/W4210518843","https://openalex.org/W3005246872","https://openalex.org/W2924084968","https://openalex.org/W4404341388","https://openalex.org/W7164385086","https://openalex.org/W2776174981","https://openalex.org/W4388706687"],"abstract_inverted_index":{"Peripheral":[0],"arterial":[1],"disease":[2],"(PAD)":[3],"is":[4],"a":[5,57,64,212,238],"prevalent":[6],"medical":[7],"condition":[8],"associated":[9],"with":[10,63,157],"high":[11,18],"mortality":[12],"and":[13,47,92,105,171,223,247],"morbidity":[14],"rates.":[15],"Despite":[16],"the":[17,70,85,88,175,204,243],"clinical":[19,45,250],"burden,":[20],"sex-based":[21,42,239],"differences":[22,43],"among":[23,49,207],"PAD":[24,67,94,199],"patients":[25,51,62,95,114,209,229],"are":[26],"not":[27,179,237],"well":[28],"defined":[29],"yet,":[30],"in":[31,44,96,174,242,255],"contrast":[32],"to":[33,40,69,77],"other":[34],"atherosclerotic":[35],"diseases.":[36],"This":[37,55],"study":[38,59,86],"aimed":[39],"describe":[41],"characteristics":[46],"outcomes":[48,251],"hospitalized":[50,228],"affected":[52,230],"by":[53,231],"PAD.":[54],"was":[56,87,236],"retrospective":[58],"evaluating":[60],"all":[61],"diagnosis":[65],"of":[66,84,99,112,130,215,220,224,245],"admitted":[68],"Emergency":[71],"Department":[72],"from":[73],"1":[74],"December":[75,79],"2013":[76],"31":[78],"2021.":[80],"The":[81],"primary":[82],"endpoint":[83],"difference":[89,241],"between":[90,203],"male":[91,176],"female":[93],"cumulative":[97],"occurrence":[98],"Major":[100,106],"Adverse":[101,107],"Cardiovascular":[102],"Events":[103],"(MACEs)":[104],"Limb":[108],"Events.":[109],"A":[110,166],"total":[111],"1640":[113],"were":[115,121,125,155,252],"enrolled.":[116],"Among":[117,227],"them,":[118],"1103":[119],"(67.3%)":[120],"males":[122,154,210],"while":[123],"females":[124],"significantly":[126],"older":[127],"(median":[128],"age":[129],"75":[131],"years":[132],"vs.":[133,149,161],"71":[134],"years;":[135],"p":[136,151,163,186,192],"=<":[137],"0.001).":[138],"Females":[139],"underwent":[140],"more":[141,158,169,253],"angioplasty":[142],"treatments":[143],"for":[144],"revascularization":[145],"than":[146],"men":[147],"(29.8%":[148],"25.6%;":[150],"=":[152,164,187,193],"0.04);":[153],"treated":[156],"amputations":[159],"(19.9%":[160],"15.3%;":[162],"0.012).":[165],"trend":[167],"toward":[168],"MALEs":[170,246],"MACEs":[172],"reported":[173],"group":[177],"did":[178],"reach":[180],"statistical":[181],"significance":[182],"(OR":[183,189],"1.27":[184],"[0.99\u20131.64];":[185],"0.059)":[188],"0.75":[190],"[0.50\u20131.11];":[191],"0.153).":[194],"However,":[195],"despite":[196],"lower":[197,217],"extremity":[198],"severity":[200],"seeming":[201],"similar":[202],"two":[205],"sexes,":[206],"these":[208],"had":[211],"higher":[213],"probability":[214],"undergoing":[216],"limb":[218],"amputations,":[219],"cardiovascular":[221],"death":[222],"myocardial":[225],"infarction.":[226],"PAD,":[232],"even":[233],"if":[234],"there":[235],"significant":[240],"incidence":[244],"MACEs,":[248],"adverse":[249],"common":[254],"males.":[256]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2023-08-04T00:00:00"}