{"id":"https://openalex.org/W4385488358","doi":"https://doi.org/10.1007/s00726-023-03306-0","title":"Comparison of homocitrulline and carbamylated albumin as biomarkers of carbamylation reactions in hemodialyzed patients","display_name":"Comparison of homocitrulline and carbamylated albumin as biomarkers of carbamylation reactions in hemodialyzed patients","publication_year":2023,"publication_date":"2023-08-02","ids":{"openalex":"https://openalex.org/W4385488358","doi":"https://doi.org/10.1007/s00726-023-03306-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/37532908","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10689527"},"language":"en","primary_location":{"id":"doi:10.1007/s00726-023-03306-0","doi":"https://doi.org/10.1007/s00726-023-03306-0","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00726-023-03306-0","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00726-023-03306-0.pdf","source":{"id":"https://openalex.org/S13895637","display_name":"Amino Acids","issn_l":"0939-4451","issn":["0939-4451","1438-2199"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino Acids","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00726-023-03306-0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026559921","display_name":"Aur\u00e9lie Lenglet","orcid":"https://orcid.org/0000-0002-5529-6684","observed_orcids":["https://orcid.org/0000-0002-5529-6684","https://orcid.org/0000-0002-6244-5369"]},"institutions":[{"id":"https://openalex.org/I4210096553","display_name":"Centre Hospitalier Universitaire Amiens-Picardie","ror":"https://ror.org/010567a58","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210096553"]},{"id":"https://openalex.org/I4401200359","display_name":"M\u00e9canismes physiopathologiques et cons\u00e9quences des calcifications cardiovasculaires","ror":"https://ror.org/00bgnvd66","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4401200359","https://openalex.org/I4647051"]},{"id":"https://openalex.org/I4647051","display_name":"Universit\u00e9 de Picardie Jules Verne","ror":"https://ror.org/01gyxrk03","country_code":"FR","type":"education","lineage":["https://openalex.org/I4647051"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Aurelie Lenglet","raw_affiliation_strings":["Pharmacy Division, Amiens University Medical Center, Amiens, France","UM7517, MP3CV Laboratory, CURS, Faculty of Pharmacy, Jules Verne University of Picardie, Amiens, France","CHU Amiens-Picardie (France)","MP3CV - M\u00e9canismes physiopathologiques et cons\u00e9quences des calcifications cardiovasculaires - UR UPJV 7517 (Universit\u00e9 de Picardie Jules Verne - Centre de Recherche Universitaire en Sant\u00e9 (CURS) - CHU Sud - rue Ren\u00e9e Laennec - \r\n80054 Amiens Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacy Division, Amiens University Medical Center, Amiens, France","institution_ids":["https://openalex.org/I4210096553"]},{"raw_affiliation_string":"UM7517, MP3CV Laboratory, CURS, Faculty of Pharmacy, Jules Verne University of Picardie, Amiens, France","institution_ids":["https://openalex.org/I4401200359","https://openalex.org/I4647051"]},{"raw_affiliation_string":"CHU Amiens-Picardie (France)","institution_ids":["https://openalex.org/I4210096553"]},{"raw_affiliation_string":"MP3CV - M\u00e9canismes physiopathologiques et cons\u00e9quences des calcifications cardiovasculaires - UR UPJV 7517 (Universit\u00e9 de Picardie Jules Verne - Centre de Recherche Universitaire en Sant\u00e9 (CURS) - CHU Sud - rue Ren\u00e9e Laennec - \r\n80054 Amiens Cedex - France)","institution_ids":["https://openalex.org/I4401200359","https://openalex.org/I4647051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002639584","display_name":"St\u00e9phane Jaisson","orcid":"https://orcid.org/0000-0002-8491-6563","observed_orcids":["https://orcid.org/0000-0002-8491-6563"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210105796","display_name":"Centre Hospitalier Universitaire de Reims","ror":"https://ror.org/01jbb3w63","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210105796"]},{"id":"https://openalex.org/I4387155780","display_name":"Matrice Extracellulaire et Dynamique Cellulaire MEDyC","ror":"https://ror.org/017p6sq53","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4387155780","https://openalex.org/I96226040"]},{"id":"https://openalex.org/I96226040","display_name":"Universit\u00e9 de Reims Champagne-Ardenne","ror":"https://ror.org/03hypw319","country_code":"FR","type":"education","lineage":["https://openalex.org/I96226040"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"St\u00e9phane Jaisson","raw_affiliation_strings":["Biochemistry Department, Reims University Medical Center, Reims, France","University of Reims Champagne-Ardenne, CNRS, MEDyC Unit UMR 7369, Reims, France","CHU Reims - H\u00f4pital universitaire Robert Debr\u00e9 [Reims] (rue du General Koenig 51090 Reims Cedex - France)","MEDyC - Matrice Extracellulaire et Dynamique Cellulaire - UMR CNRS 7369 (UFR Sciences Exactes et Naturelles\r\nCampus Moulin de la Housse\r\n51687 REIMS Cedex 2\r\nFRANCE - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Department, Reims University Medical Center, Reims, France","institution_ids":["https://openalex.org/I4210105796"]},{"raw_affiliation_string":"University of Reims Champagne-Ardenne, CNRS, MEDyC Unit UMR 7369, Reims, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4387155780","https://openalex.org/I96226040"]},{"raw_affiliation_string":"CHU Reims - H\u00f4pital universitaire Robert Debr\u00e9 [Reims] (rue du General Koenig 51090 Reims Cedex - France)","institution_ids":["https://openalex.org/I4210105796"]},{"raw_affiliation_string":"MEDyC - Matrice Extracellulaire et Dynamique Cellulaire - UMR CNRS 7369 (UFR Sciences Exactes et Naturelles\r\nCampus Moulin de la Housse\r\n51687 REIMS Cedex 2\r\nFRANCE - France)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4387155780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060274898","display_name":"Philippe Gillery","orcid":"https://orcid.org/0000-0002-1100-8759","observed_orcids":["https://orcid.org/0000-0002-1100-8759"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210105796","display_name":"Centre Hospitalier Universitaire de Reims","ror":"https://ror.org/01jbb3w63","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210105796"]},{"id":"https://openalex.org/I4387155780","display_name":"Matrice Extracellulaire et Dynamique Cellulaire MEDyC","ror":"https://ror.org/017p6sq53","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4387155780","https://openalex.org/I96226040"]},{"id":"https://openalex.org/I96226040","display_name":"Universit\u00e9 de Reims Champagne-Ardenne","ror":"https://ror.org/03hypw319","country_code":"FR","type":"education","lineage":["https://openalex.org/I96226040"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Philippe Gillery","raw_affiliation_strings":["Biochemistry Department, Reims University Medical Center, Reims, France","University of Reims Champagne-Ardenne, CNRS, MEDyC Unit UMR 7369, Reims, France","CHU Reims - H\u00f4pital universitaire Robert Debr\u00e9 [Reims] (rue du General Koenig 51090 Reims Cedex - France)","MEDyC - Matrice Extracellulaire et Dynamique Cellulaire - UMR CNRS 7369 (UFR Sciences Exactes et Naturelles\r\nCampus Moulin de la Housse\r\n51687 REIMS Cedex 2\r\nFRANCE - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Department, Reims University Medical Center, Reims, France","institution_ids":["https://openalex.org/I4210105796"]},{"raw_affiliation_string":"University of Reims Champagne-Ardenne, CNRS, MEDyC Unit UMR 7369, Reims, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4387155780","https://openalex.org/I96226040"]},{"raw_affiliation_string":"CHU Reims - H\u00f4pital universitaire Robert Debr\u00e9 [Reims] (rue du General Koenig 51090 Reims Cedex - France)","institution_ids":["https://openalex.org/I4210105796"]},{"raw_affiliation_string":"MEDyC - Matrice Extracellulaire et Dynamique Cellulaire - UMR CNRS 7369 (UFR Sciences Exactes et Naturelles\r\nCampus Moulin de la Housse\r\n51687 REIMS Cedex 2\r\nFRANCE - France)","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4387155780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013145133","display_name":"Souleiman El Balkhi","orcid":"https://orcid.org/0000-0002-9743-5603","observed_orcids":["https://orcid.org/0000-0002-9743-5603"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4405284615","display_name":"Ciblage individuel et pr\u00e9vention des risques de traitements immunosupresseurs et de la transplantation","ror":"https://ror.org/03wbncc78","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I4210118469","https://openalex.org/I4387153263","https://openalex.org/I4405284615","https://openalex.org/I65806277"]},{"id":"https://openalex.org/I65806277","display_name":"Universit\u00e9 de Limoges","ror":"https://ror.org/02cp04407","country_code":"FR","type":"education","lineage":["https://openalex.org/I65806277"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Souleiman El Balkhi","raw_affiliation_strings":["INSERM, IPPRITT, U1248, 87000, Limoges, France","IPPRITT - Ciblage individuel et pr\u00e9vention des risques de traitements immunosupresseurs et de la transplantation (Centre de Biologie et de Recherche en Sant\u00e9 (CBRS), 2\u00e8me \u00e9tage Rue du Pr. Bernard Descottes 87025 LIMOGES Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM, IPPRITT, U1248, 87000, Limoges, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I65806277"]},{"raw_affiliation_string":"IPPRITT - Ciblage individuel et pr\u00e9vention des risques de traitements immunosupresseurs et de la transplantation (Centre de Biologie et de Recherche en Sant\u00e9 (CBRS), 2\u00e8me \u00e9tage Rue du Pr. Bernard Descottes 87025 LIMOGES Cedex - France)","institution_ids":["https://openalex.org/I4405284615","https://openalex.org/I65806277"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033170314","display_name":"Sophie Liabeuf","orcid":"https://orcid.org/0000-0001-5384-9006","observed_orcids":["https://orcid.org/0000-0001-5384-9006"]},"institutions":[{"id":"https://openalex.org/I4210096553","display_name":"Centre Hospitalier Universitaire Amiens-Picardie","ror":"https://ror.org/010567a58","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210096553"]},{"id":"https://openalex.org/I4210133069","display_name":"H\u00f4pital Ambroise-Par\u00e9","ror":"https://ror.org/03j6rvb05","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210133069"]},{"id":"https://openalex.org/I4401200359","display_name":"M\u00e9canismes physiopathologiques et cons\u00e9quences des calcifications cardiovasculaires","ror":"https://ror.org/00bgnvd66","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4401200359","https://openalex.org/I4647051"]},{"id":"https://openalex.org/I4647051","display_name":"Universit\u00e9 de Picardie Jules Verne","ror":"https://ror.org/01gyxrk03","country_code":"FR","type":"education","lineage":["https://openalex.org/I4647051"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sophie Liabeuf","raw_affiliation_strings":["Division of Nephrology, Ambroise Par\u00e9 Hospital and Paris Ile de France Ouest University, 9 Avenue Charles de Gaulle, 92104, Boulogne Billancourt Cedex, France","UM7517, MP3CV Laboratory, CURS, Faculty of Pharmacy, Jules Verne University of Picardie, Amiens, France","CHU Amiens-Picardie (France)","MP3CV - M\u00e9canismes physiopathologiques et cons\u00e9quences des calcifications cardiovasculaires - UR UPJV 7517 (Universit\u00e9 de Picardie Jules Verne - Centre de Recherche Universitaire en Sant\u00e9 (CURS) - CHU Sud - rue Ren\u00e9e Laennec - \r\n80054 Amiens Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Ambroise Par\u00e9 Hospital and Paris Ile de France Ouest University, 9 Avenue Charles de Gaulle, 92104, Boulogne Billancourt Cedex, France","institution_ids":["https://openalex.org/I4210133069"]},{"raw_affiliation_string":"UM7517, MP3CV Laboratory, CURS, Faculty of Pharmacy, Jules Verne University of Picardie, Amiens, France","institution_ids":["https://openalex.org/I4401200359","https://openalex.org/I4647051"]},{"raw_affiliation_string":"CHU Amiens-Picardie (France)","institution_ids":["https://openalex.org/I4210096553"]},{"raw_affiliation_string":"MP3CV - M\u00e9canismes physiopathologiques et cons\u00e9quences des calcifications cardiovasculaires - UR UPJV 7517 (Universit\u00e9 de Picardie Jules Verne - Centre de Recherche Universitaire en Sant\u00e9 (CURS) - CHU Sud - rue Ren\u00e9e Laennec - \r\n80054 Amiens Cedex - France)","institution_ids":["https://openalex.org/I4401200359","https://openalex.org/I4647051"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071660720","display_name":"Ziad A. Massy","orcid":"https://orcid.org/0000-0001-5771-5996","observed_orcids":["https://orcid.org/0000-0001-5771-5996"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I195731000","display_name":"Universit\u00e9 de Versailles Saint-Quentin-en-Yvelines","ror":"https://ror.org/03mkjjy25","country_code":"FR","type":"education","lineage":["https://openalex.org/I195731000","https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210103698","display_name":"Centre de recherche en Epid\u00e9miologie et Sant\u00e9 des Populations","ror":"https://ror.org/01ed4t417","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I195731000","https://openalex.org/I277688954","https://openalex.org/I4210097159","https://openalex.org/I4210103698","https://openalex.org/I4210164847","https://openalex.org/I4405259118"]},{"id":"https://openalex.org/I4210133069","display_name":"H\u00f4pital Ambroise-Par\u00e9","ror":"https://ror.org/03j6rvb05","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210133069"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Ziad A. Massy","raw_affiliation_strings":["Division of Nephrology, Ambroise Par\u00e9 Hospital and Paris Ile de France Ouest University, 9 Avenue Charles de Gaulle, 92104, Boulogne Billancourt Cedex, France. ziad.massy@aphp.fr","INSERM U-1018, Centre de recherche en \u00e9pid\u00e9miologie et sant\u00e9 des populations (CESP), Paris-Saclay University (PSU) and University of Paris Ouest-Versailles-Saint-Quentin-en-Yvelines (UVSQ), Equipe 5, Villejuif, France. ziad.massy@aphp.fr","Service N\u00e9phrologie/Dialyse [AP-HP Ambroise-Par\u00e9] (9 Avenue Charles de Gaulle 92100 Boulogne-Billancourt - France)","U1018 (\u00c9quipe 5) - \u00c9pid\u00e9miologie et recherches translationnelles sur les maladies r\u00e9nales et cardiovasculaires (EPREC) (16 av, Paul Vaillant Couturier 94807 Villejuif - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Ambroise Par\u00e9 Hospital and Paris Ile de France Ouest University, 9 Avenue Charles de Gaulle, 92104, Boulogne Billancourt Cedex, France. ziad.massy@aphp.fr","institution_ids":["https://openalex.org/I4210133069"]},{"raw_affiliation_string":"INSERM U-1018, Centre de recherche en \u00e9pid\u00e9miologie et sant\u00e9 des populations (CESP), Paris-Saclay University (PSU) and University of Paris Ouest-Versailles-Saint-Quentin-en-Yvelines (UVSQ), Equipe 5, Villejuif, France. ziad.massy@aphp.fr","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I195731000","https://openalex.org/I4210103698"]},{"raw_affiliation_string":"Service N\u00e9phrologie/Dialyse [AP-HP Ambroise-Par\u00e9] (9 Avenue Charles de Gaulle 92100 Boulogne-Billancourt - France)","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210133069"]},{"raw_affiliation_string":"U1018 (\u00c9quipe 5) - \u00c9pid\u00e9miologie et recherches translationnelles sur les maladies r\u00e9nales et cardiovasculaires (EPREC) (16 av, Paul Vaillant Couturier 94807 Villejuif - France)","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5071660720"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I195731000","https://openalex.org/I4210097159","https://openalex.org/I4210103698","https://openalex.org/I4210133069"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":{"value":3590,"currency":"USD","value_usd":3590},"fwci":1.5998,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.81534479,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"55","issue":"10","first_page":"1455","last_page":"1460"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/homocitrulline","display_name":"homocitrulline","score":0.9990000128746033},{"id":"https://openalex.org/keywords/protein-carbamylation","display_name":"protein carbamylation","score":0.953000009059906},{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.7860000133514404},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.9020000100135803},{"id":"https://openalex.org/keywords/sevelamer","display_name":"sevelamer","score":0.9580000042915344},{"id":"https://openalex.org/keywords/nicotinamide","display_name":"nicotinamide","score":0.9990000128746033},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.7879999876022339},{"id":"https://openalex.org/keywords/uremic-toxins","display_name":"uremic toxins","score":0.6589999794960022}],"concepts":[{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.7464069724082947},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6456066370010376},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.549227237701416},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.49657493829727173},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4100250005722046},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.347297340631485},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1394304633140564},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069603","descriptor_name":"Sevelamer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077279","descriptor_name":"Protein Carbamylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000418","descriptor_name":"Albumins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002853","descriptor_name":"Chromatography, Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002956","descriptor_name":"Citrulline","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009536","descriptor_name":"Niacinamide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053719","descriptor_name":"Tandem Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1007/s00726-023-03306-0","doi":"https://doi.org/10.1007/s00726-023-03306-0","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00726-023-03306-0","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00726-023-03306-0.pdf","source":{"id":"https://openalex.org/S13895637","display_name":"Amino Acids","issn_l":"0939-4451","issn":["0939-4451","1438-2199"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino Acids","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-2332796/v1","doi":"https://doi.org/10.21203/rs.3.rs-2332796/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-2332796/v1","pdf_url":"https://www.researchsquare.com/article/rs-2332796/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10689527","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10689527","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10689527/pdf/726_2023_Article_3306.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino Acids","raw_type":"Text"},{"id":"pmid:37532908","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37532908","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino acids","raw_type":"Comparative Study"},{"id":"pmh:oai:HAL:hal-04176949v1","doi":null,"is_oa":true,"landing_page_url":"https://u-picardie.hal.science/hal-04176949","pdf_url":"https://u-picardie.hal.science/hal-04176949/document","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Amino Acids, 2023, 55 (10), pp.1455-1460. ⟨10.1007/s00726-023-03306-0⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1007/s00726-023-03306-0","doi":"https://doi.org/10.1007/s00726-023-03306-0","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00726-023-03306-0","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00726-023-03306-0.pdf","source":{"id":"https://openalex.org/S13895637","display_name":"Amino Acids","issn_l":"0939-4451","issn":["0939-4451","1438-2199"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Amino Acids","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.979200005531311}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"},{"id":"https://openalex.org/F4320307758","display_name":"Eli Lilly and Company","ror":"https://ror.org/01qat3289"},{"id":"https://openalex.org/F4320323024","display_name":"Astellas Pharma","ror":"https://ror.org/01cjash87"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4385488358.pdf","grobid_xml":"https://content.openalex.org/works/W4385488358.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1981267246","https://openalex.org/W2004965454","https://openalex.org/W2033513345","https://openalex.org/W2072840355","https://openalex.org/W2073363749","https://openalex.org/W2106617121","https://openalex.org/W2327831560","https://openalex.org/W2346622855","https://openalex.org/W2416591823","https://openalex.org/W2418106082","https://openalex.org/W2802119406","https://openalex.org/W3171081059","https://openalex.org/W4212999537","https://openalex.org/W4318993843","https://openalex.org/W4366993252"],"related_works":["https://openalex.org/W2418106082","https://openalex.org/W177163261","https://openalex.org/W1987332882","https://openalex.org/W4397041951","https://openalex.org/W2026626334","https://openalex.org/W2089374494","https://openalex.org/W4399157020","https://openalex.org/W2006094034","https://openalex.org/W2075511935","https://openalex.org/W2483512899"],"abstract_inverted_index":{"To":[0],"describe":[1],"the":[2,10,68,127,137],"association":[3],"between":[4],"levels":[5],"of":[6,12,18,46,70,75,89,126,130,154],"homocitrulline":[7],"(HCit)":[8],"and":[9,23,42,58,64,80,103,118,140],"degree":[11,69],"albumin":[13,71,82,111],"carbamylation":[14,112,132,155],"in":[15,27,33,59,113,133,150],"a":[16],"cohort":[17],"hemodialyzed":[19,30,114],"patients.":[20,115],"Plasma":[21,73],"total":[22,76,102,117],"protein-bound":[24,78,104,119],"HCit":[25,53,79,105,120],"concentrations":[26,54,74,106,121],"samples":[28],"from":[29],"patients":[31],"included":[32],"NICOREN":[34],"trial":[35],"were":[36,62,107],"determined":[37],"by":[38],"LC-MS/MS":[39],"at":[40,55],"baseline":[41],"after":[43,86],"24":[44,87],"weeks":[45,88],"treatment":[47,90],"with":[48,67,91,110],"either":[49,92],"sevelamer":[50,93],"or":[51,94],"nicotinamide.":[52,95],"all":[56],"timepoints":[57],"both":[60],"groups":[61],"positively":[63],"significantly":[65],"correlated":[66],"carbamylation.":[72],"HCit,":[77],"carbamylated":[81],"did":[83],"not":[84],"decrease":[85],"The":[96],"present":[97],"results":[98],"demonstrate":[99],"that":[100],"plasma":[101],"closely":[108],"associated":[109],"Therefore,":[116],"might":[122],"be":[123,148],"valuable":[124],"biomarkers":[125],"overall":[128],"intensity":[129],"protein":[131],"this":[134],"context.":[135],"Given":[136],"less":[138],"complex":[139],"time-consuming":[141],"analytical":[142],"methods":[143],"required,":[144],"these":[145],"markers":[146],"should":[147],"favored":[149],"future":[151],"clinical":[152],"studies":[153],"reaction.":[156]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2023-08-03T00:00:00"}