{"id":"https://openalex.org/W4385236342","doi":"https://doi.org/10.4149/neo_2023_230525n283","title":"Effects of different-sized silver nanoparticles on morphological and functional alterations in lung cancer and non-cancer lung cells","display_name":"Effects of different-sized silver nanoparticles on morphological and functional alterations in lung cancer and non-cancer lung cells","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4385236342","doi":"https://doi.org/10.4149/neo_2023_230525n283","pmid":"https://pubmed.ncbi.nlm.nih.gov/37498075"},"language":"en","primary_location":{"id":"doi:10.4149/neo_2023_230525n283","doi":"https://doi.org/10.4149/neo_2023_230525n283","is_oa":true,"landing_page_url":"https://doi.org/10.4149/neo_2023_230525n283","pdf_url":"http://www.elis.sk/download_file.php?product_id=8108&session_id=bm390k39s3mltvjatmuangehl4","source":{"id":"https://openalex.org/S52683455","display_name":"Neoplasma","issn_l":"0028-2685","issn":["0028-2685","1338-4317"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310314442","host_organization_name":"AEPress","host_organization_lineage":["https://openalex.org/P4310314442"],"host_organization_lineage_names":["AEPress"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neoplasma","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.elis.sk/download_file.php?product_id=8108&session_id=bm390k39s3mltvjatmuangehl4","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087290631","display_name":"Krist\u00edna Jaki\u010d","orcid":"https://orcid.org/0000-0002-8251-5328","observed_orcids":["https://orcid.org/0000-0002-8251-5328"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210121077","display_name":"Cancer Research Institute of the Slovak Academy of Sciences","ror":"https://ror.org/02v8wkr26","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210121077","https://openalex.org/I4210123996"]},{"id":"https://openalex.org/I4210123996","display_name":"Biomedical Research Center of the Slovak Academy of Sciences","ror":"https://ror.org/02s3ds748","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210123996"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Kristina Jakic","raw_affiliation_strings":["Department of Nanobiology, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nanobiology, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210121077","https://openalex.org/I4210123996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061127746","display_name":"Michal \u0160elc","orcid":"https://orcid.org/0000-0002-7330-6655","observed_orcids":["https://orcid.org/0000-0002-7330-6655"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210121077","display_name":"Cancer Research Institute of the Slovak Academy of Sciences","ror":"https://ror.org/02v8wkr26","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210121077","https://openalex.org/I4210123996"]},{"id":"https://openalex.org/I4210122975","display_name":"Centre for Advanced Material Application of the Slovak Academy of Sciences","ror":"https://ror.org/02snrxw52","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210122975"]},{"id":"https://openalex.org/I4210123996","display_name":"Biomedical Research Center of the Slovak Academy of Sciences","ror":"https://ror.org/02s3ds748","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210123996"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Michal Selc","raw_affiliation_strings":["Centre for Advanced Material Application, Slovak Academy of Sciences, Bratislava, Slovakia","Department of Nanobiology, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Advanced Material Application, Slovak Academy of Sciences, Bratislava, Slovakia","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210122975"]},{"raw_affiliation_string":"Department of Nanobiology, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210121077","https://openalex.org/I4210123996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092537745","display_name":"Radka Macova","orcid":"https://orcid.org/0000-0002-3033-4648","observed_orcids":["https://orcid.org/0000-0002-3033-4648"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210121077","display_name":"Cancer Research Institute of the Slovak Academy of Sciences","ror":"https://ror.org/02v8wkr26","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210121077","https://openalex.org/I4210123996"]},{"id":"https://openalex.org/I4210123996","display_name":"Biomedical Research Center of the Slovak Academy of Sciences","ror":"https://ror.org/02s3ds748","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210123996"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Radka Macova","raw_affiliation_strings":["Department of Nanobiology, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nanobiology, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210121077","https://openalex.org/I4210123996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092060028","display_name":"Ant\u00f3nia Kurillov\u00e1","orcid":"https://orcid.org/0000-0002-8611-0950","observed_orcids":["https://orcid.org/0000-0002-8611-0950"]},"institutions":[{"id":"https://openalex.org/I70703428","display_name":"Palack\u00fd University Olomouc","ror":"https://ror.org/04qxnmv42","country_code":"CZ","type":"education","lineage":["https://openalex.org/I70703428"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Antonia Kurillova","raw_affiliation_strings":["Department of Physical Chemistry, Faculty of Science, Palacky University in Olomouc, Olomouc, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Chemistry, Faculty of Science, Palacky University in Olomouc, Olomouc, Czech Republic","institution_ids":["https://openalex.org/I70703428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004248358","display_name":"Libor Kv\u00edtek","orcid":"https://orcid.org/0000-0003-2005-560X","observed_orcids":["https://orcid.org/0000-0003-2005-560X"]},"institutions":[{"id":"https://openalex.org/I70703428","display_name":"Palack\u00fd University Olomouc","ror":"https://ror.org/04qxnmv42","country_code":"CZ","type":"education","lineage":["https://openalex.org/I70703428"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Libor Kvitek","raw_affiliation_strings":["Department of Physical Chemistry, Faculty of Science, Palacky University in Olomouc, Olomouc, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Chemistry, Faculty of Science, Palacky University in Olomouc, Olomouc, Czech Republic","institution_ids":["https://openalex.org/I70703428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056647783","display_name":"Ale\u0161 Pan\u00e1\u010dek","orcid":"https://orcid.org/0000-0001-5429-9966","observed_orcids":["https://orcid.org/0000-0001-5429-9966"]},"institutions":[{"id":"https://openalex.org/I70703428","display_name":"Palack\u00fd University Olomouc","ror":"https://ror.org/04qxnmv42","country_code":"CZ","type":"education","lineage":["https://openalex.org/I70703428"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"Ales Panacek*","raw_affiliation_strings":["Department of Physical Chemistry, Faculty of Science, Palacky University in Olomouc, Olomouc, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Chemistry, Faculty of Science, Palacky University in Olomouc, Olomouc, Czech Republic","institution_ids":["https://openalex.org/I70703428"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059864807","display_name":"Andrea B\u00e1belov\u00e1","orcid":"https://orcid.org/0000-0001-9548-6602","observed_orcids":["https://orcid.org/0000-0001-9548-6602"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210121077","display_name":"Cancer Research Institute of the Slovak Academy of Sciences","ror":"https://ror.org/02v8wkr26","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210121077","https://openalex.org/I4210123996"]},{"id":"https://openalex.org/I4210122975","display_name":"Centre for Advanced Material Application of the Slovak Academy of Sciences","ror":"https://ror.org/02snrxw52","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210122975"]},{"id":"https://openalex.org/I4210123996","display_name":"Biomedical Research Center of the Slovak Academy of Sciences","ror":"https://ror.org/02s3ds748","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210123996"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Andrea Babelova","raw_affiliation_strings":["Centre for Advanced Material Application, Slovak Academy of Sciences, Bratislava, Slovakia","Department of Nanobiology, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Advanced Material Application, Slovak Academy of Sciences, Bratislava, Slovakia","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210122975"]},{"raw_affiliation_string":"Department of Nanobiology, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210121077","https://openalex.org/I4210123996"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2022,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.28863392,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"70","issue":"03","first_page":"390","last_page":"401"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/silver-nanoparticles","display_name":"silver nanoparticles","score":1.0},{"id":"https://openalex.org/keywords/nanoparticle-size","display_name":"nanoparticle size","score":0.8130000233650208},{"id":"https://openalex.org/keywords/polyacrylic-acid-coating","display_name":"polyacrylic acid coating","score":0.9120000004768372},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"lung cancer","score":0.6729999780654907},{"id":"https://openalex.org/keywords/a549-cells","display_name":"A549 cells","score":0.9539999961853027},{"id":"https://openalex.org/keywords/nanoparticle-toxicity","display_name":"nanoparticle toxicity","score":0.7910000085830688},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8370000123977661},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.7089999914169312},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.9589999914169312},{"id":"https://openalex.org/keywords/actin-cytoskeleton-reorganization","display_name":"actin cytoskeleton remodeling","score":0.9169999957084656},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.7310000061988831},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fibronectin-1","display_name":"FN1","score":0.8199999928474426},{"id":"https://openalex.org/keywords/sod1","display_name":"SOD1","score":0.9639999866485596},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.628000020980835},{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C31499863","wikidata":"https://www.wikidata.org/wiki/Q905762","display_name":"Silver nanoparticle","level":3,"score":0.7795928716659546},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.6918007731437683},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.6755324006080627},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6048958897590637},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6036630868911743},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6010949015617371},{"id":"https://openalex.org/C2780312654","wikidata":"https://www.wikidata.org/wiki/Q409762","display_name":"Polyacrylic acid","level":3,"score":0.5635831952095032},{"id":"https://openalex.org/C127445965","wikidata":"https://www.wikidata.org/wiki/Q2518429","display_name":"Nanotoxicology","level":3,"score":0.5269447565078735},{"id":"https://openalex.org/C81729549","wikidata":"https://www.wikidata.org/wiki/Q4649475","display_name":"A549 cell","level":3,"score":0.4875470995903015},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4691150486469269},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4379366338253021},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.4338015615940094},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.42770296335220337},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4060696065425873},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3452182412147522},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.34250497817993164},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.3226082921028137},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23820704221725464},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.20274701714515686},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19838973879814148},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1947680413722992},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1942003071308136},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10333457589149475},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012834","descriptor_name":"Silver","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012834","descriptor_name":"Silver","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.4149/neo_2023_230525n283","doi":"https://doi.org/10.4149/neo_2023_230525n283","is_oa":true,"landing_page_url":"https://doi.org/10.4149/neo_2023_230525n283","pdf_url":"http://www.elis.sk/download_file.php?product_id=8108&session_id=bm390k39s3mltvjatmuangehl4","source":{"id":"https://openalex.org/S52683455","display_name":"Neoplasma","issn_l":"0028-2685","issn":["0028-2685","1338-4317"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310314442","host_organization_name":"AEPress","host_organization_lineage":["https://openalex.org/P4310314442"],"host_organization_lineage_names":["AEPress"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neoplasma","raw_type":"journal-article"},{"id":"pmid:37498075","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37498075","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neoplasma","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.4149/neo_2023_230525n283","doi":"https://doi.org/10.4149/neo_2023_230525n283","is_oa":true,"landing_page_url":"https://doi.org/10.4149/neo_2023_230525n283","pdf_url":"http://www.elis.sk/download_file.php?product_id=8108&session_id=bm390k39s3mltvjatmuangehl4","source":{"id":"https://openalex.org/S52683455","display_name":"Neoplasma","issn_l":"0028-2685","issn":["0028-2685","1338-4317"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310314442","host_organization_name":"AEPress","host_organization_lineage":["https://openalex.org/P4310314442"],"host_organization_lineage_names":["AEPress"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neoplasma","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1993731977","display_name":null,"funder_award_id":"ITMS project code 313021T081","funder_id":"https://openalex.org/F4320312330","funder_display_name":"Slovensk\u00e1 Akad\u00e9mia Vied"},{"id":"https://openalex.org/G2067166726","display_name":"Nano\u010dastice zlata: vplyv fyzik\u00e1lno-chemick\u00fdch vlastnost\u00ed na ich distrib\u00faciu, akumul\u00e1ciu a dlhodob\u00fa toxicitu in vivo (BIONANOGOLD)","funder_award_id":"APVV-16-0579","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G2713699836","display_name":"Diagnostika onkologick\u00fdch ochoren\u00ed pomocou aptasenzorov: v\u00fdvoj a valid\u00e1cia","funder_award_id":"2/0160/21","funder_id":"https://openalex.org/F4320323641","funder_display_name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV"},{"id":"https://openalex.org/G3926152621","display_name":null,"funder_award_id":"ITMS project code 313021T081","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G4188428110","display_name":null,"funder_award_id":"NU20-05-00165","funder_id":"https://openalex.org/F4320321798","funder_display_name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky"},{"id":"https://openalex.org/G4359724931","display_name":null,"funder_award_id":"313021T081","funder_id":"https://openalex.org/F4320323641","funder_display_name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV"},{"id":"https://openalex.org/G6255000251","display_name":"Porovnanie \u00fa\u010dinku nanosf\u00e9r a nanobipyram\u00edd zlata konjugovan\u00fdch so silibin\u00ednom pri lie\u010dbe fibr\u00f3zy pe\u010dene in vivo.","funder_award_id":"2/0116/22","funder_id":"https://openalex.org/F4320323641","funder_display_name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV"},{"id":"https://openalex.org/G777136408","display_name":null,"funder_award_id":"313021 T081","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G8767667444","display_name":null,"funder_award_id":"313021T081","funder_id":"https://openalex.org/F4320312330","funder_display_name":"Slovensk\u00e1 Akad\u00e9mia Vied"}],"funders":[{"id":"https://openalex.org/F4320312330","display_name":"Slovensk\u00e1 Akad\u00e9mia Vied","ror":"https://ror.org/03h7qq074"},{"id":"https://openalex.org/F4320321798","display_name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","ror":"https://ror.org/00y6khe77"},{"id":"https://openalex.org/F4320323251","display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja","ror":"https://ror.org/037nx0e70"},{"id":"https://openalex.org/F4320323641","display_name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV","ror":"https://ror.org/044gwpv05"},{"id":"https://openalex.org/F4320324127","display_name":"Univerzita Palack\u00e9ho v Olomouci","ror":"https://ror.org/04qxnmv42"},{"id":"https://openalex.org/F4320335322","display_name":"European Regional Development Fund","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4385236342.pdf","grobid_xml":"https://content.openalex.org/works/W4385236342.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1502477745","https://openalex.org/W1973297304","https://openalex.org/W2028889452","https://openalex.org/W2030342141","https://openalex.org/W2031603911","https://openalex.org/W2031938767","https://openalex.org/W2060181228","https://openalex.org/W2070842131","https://openalex.org/W2089155556","https://openalex.org/W2094262202","https://openalex.org/W2095235189","https://openalex.org/W2099460741","https://openalex.org/W2111424797","https://openalex.org/W2125126644","https://openalex.org/W2130406156","https://openalex.org/W2134615974","https://openalex.org/W2137931447","https://openalex.org/W2139891037","https://openalex.org/W2141237239","https://openalex.org/W2146467574","https://openalex.org/W2164974807","https://openalex.org/W2165434824","https://openalex.org/W2168611799","https://openalex.org/W2333676921","https://openalex.org/W2346329812","https://openalex.org/W2466983808","https://openalex.org/W2807092944","https://openalex.org/W2899791391","https://openalex.org/W2943002286","https://openalex.org/W2955180832","https://openalex.org/W2988965691","https://openalex.org/W3026620912","https://openalex.org/W3135231065","https://openalex.org/W4285595323","https://openalex.org/W4289731026","https://openalex.org/W4297184256","https://openalex.org/W4392145873"],"related_works":["https://openalex.org/W2954546417","https://openalex.org/W7138996673","https://openalex.org/W7119149671","https://openalex.org/W2993742786","https://openalex.org/W2913243490","https://openalex.org/W2811408870","https://openalex.org/W7053392089","https://openalex.org/W2043304167","https://openalex.org/W2323184505","https://openalex.org/W7030444938"],"abstract_inverted_index":{"Silver":[0],"nanoparticles":[1,132],"(AgNPs)":[2],"exhibit":[3],"unique":[4],"physicochemical":[5],"properties,":[6],"making":[7],"these":[8,131,206],"nanomaterials":[9],"attractive":[10],"for":[11],"various":[12],"medical":[13],"applications.":[14],"Among":[15],"them,":[16],"AgNPs":[17,97,186],"have":[18],"shown":[19],"great":[20],"potential":[21],"in":[22,30,75,114,116,145,173,205],"the":[23,38,51,68,93,99,128,146,164,170,180,184],"treatment":[24,78],"of":[25,40,55,67,77,95,103,130,148],"cancer":[26,31,42,120,190],"by":[27,156],"inducing":[28],"apoptosis":[29,174],"cells,":[32,193],"inhibiting":[33],"tumor":[34],"growth,":[35],"and":[36,47,85,106,122,138,152,191,197],"enhancing":[37],"efficacy":[39],"conventional":[41],"treatments":[43],"such":[44],"as":[45],"chemotherapy":[46],"radiation":[48],"therapy.":[49],"Despite":[50],"promising":[52],"therapeutical":[53],"advantage":[54],"AgNPs,":[56],"there":[57],"are":[58,169,178],"several":[59],"challenges":[60],"that":[61,163],"need":[62],"to":[63,82,188],"be":[64,80],"addressed.":[65],"One":[66],"most":[69,171,181],"important":[70],"is":[71],"AgNPs'":[72],"toxicity,":[73],"which":[74],"case":[76],"might":[79],"extended":[81],"non-cancerous":[83],"cells":[84],"tissues.":[86],"In":[87],"our":[88],"study,":[89],"we":[90],"therefore":[91],"investigated":[92],"effects":[94,204],"spherical":[96],"with":[98,110],"silver":[100],"core":[101],"size":[102],"10,":[104],"30,":[105],"45":[107,198],"nm":[108],"coated":[109],"polyacrylic":[111],"acid":[112],"(PAA-AgNPs)":[113],"an":[115],"vitro":[117],"model":[118],"using":[119],"(A549)":[121],"non-cancer":[123,192],"(HEL299)":[124],"cells.":[125,208],"We":[126],"estimated":[127],"impact":[129],"on":[133],"cell":[134,136,139],"viability,":[135],"proliferation,":[137],"actin":[140],"cytoskeleton":[141],"remodeling.":[142],"Moreover,":[143],"changes":[144],"expression":[147],"TNFA,":[149],"IL-10,":[150],"FN1,":[151],"SOD1":[153],"mRNA":[154],"induced":[155],"PAA-AgNPs":[157,168,200],"were":[158],"determined.":[159],"Our":[160],"results":[161],"suggest":[162],"smallest":[165],"(10":[166],"nm)":[167,199],"effective":[172],"induction,":[175],"however,":[176],"they":[177],"also":[179],"toxic":[182],"from":[183],"three":[185],"types":[187],"both,":[189],"while":[194],"bigger":[195],"(30":[196],"showed":[201],"fewer":[202],"undesirable":[203],"pulmonary":[207]},"counts_by_year":[{"year":2025,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-07-26T00:00:00"}