{"id":"https://openalex.org/W4385076381","doi":"https://doi.org/10.1093/ageing/afad104.093","title":"1492 EFFECTIVENESS OF EXERCISE INTERVENTIONS ON BODY COMPOSITION AND FUNCTIONAL OUTCOMES IN SARCOPENIA: A SYSTEMATIC REVIEW","display_name":"1492 EFFECTIVENESS OF EXERCISE INTERVENTIONS ON BODY COMPOSITION AND FUNCTIONAL OUTCOMES IN SARCOPENIA: A SYSTEMATIC REVIEW","publication_year":2023,"publication_date":"2023-07-01","ids":{"openalex":"https://openalex.org/W4385076381","doi":"https://doi.org/10.1093/ageing/afad104.093"},"language":"en","primary_location":{"id":"doi:10.1093/ageing/afad104.093","doi":"https://doi.org/10.1093/ageing/afad104.093","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1093/ageing/afad104.093","pdf_url":null,"source":{"id":"https://openalex.org/S31768639","display_name":"Age and Ageing","issn_l":"0002-0729","issn":["0002-0729","1468-2834"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Age and Ageing","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111306737","display_name":"Huma Syed Hussain","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169199633","display_name":"Aston University","ror":"https://ror.org/05j0ve876","country_code":"GB","type":"education","lineage":["https://openalex.org/I169199633"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"H Hussain","raw_affiliation_strings":["Aston Medical School","Aston University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aston Medical School","institution_ids":["https://openalex.org/I169199633"]},{"raw_affiliation_string":"Aston University","institution_ids":["https://openalex.org/I169199633"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111306737"],"corresponding_institution_ids":["https://openalex.org/I169199633"],"apc_list":{"value":2573,"currency":"GBP","value_usd":3200},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13501442,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"52","issue":"Supplement_2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sarcopenia","display_name":"sarcopenia","score":1.0},{"id":"https://openalex.org/keywords/exercise-intervention","display_name":"exercise intervention","score":0.9810000061988831},{"id":"https://openalex.org/keywords/body-composition","display_name":"body composition","score":0.7250000238418579},{"id":"https://openalex.org/keywords/appendicular-skeletal-muscle-mass","display_name":"appendicular skeletal muscle mass","score":0.8849999904632568},{"id":"https://openalex.org/keywords/muscle-strength","display_name":"muscle strength","score":0.9309999942779541},{"id":"https://openalex.org/keywords/physical-functioning","display_name":"physical function","score":0.8569999933242798},{"id":"https://openalex.org/keywords/timed-up-and-go-test","display_name":"Timed Up and Go test","score":0.9169999957084656},{"id":"https://openalex.org/keywords/handgrip-strength","display_name":"grip strength","score":0.9990000128746033},{"id":"https://openalex.org/keywords/quadriceps-strength","display_name":"quadriceps strength","score":0.9789999723434448},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.8410000205039978},{"id":"https://openalex.org/keywords/dietary-intervention","display_name":"dietary intervention","score":0.8259999752044678},{"id":"https://openalex.org/keywords/pharmacological-interventions","display_name":"pharmacological interventions","score":0.9879999756813049}],"concepts":[{"id":"https://openalex.org/C2776214593","wikidata":"https://www.wikidata.org/wiki/Q1787939","display_name":"Sarcopenia","level":2,"score":0.9554041624069214},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8680402040481567},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.7266989946365356},{"id":"https://openalex.org/C2777433710","wikidata":"https://www.wikidata.org/wiki/Q5609571","display_name":"Grip strength","level":2,"score":0.654166042804718},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6232895255088806},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.5890477299690247},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.43724310398101807},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31440895795822144},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/ageing/afad104.093","doi":"https://doi.org/10.1093/ageing/afad104.093","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1093/ageing/afad104.093","pdf_url":null,"source":{"id":"https://openalex.org/S31768639","display_name":"Age and Ageing","issn_l":"0002-0729","issn":["0002-0729","1468-2834"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Age and Ageing","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2796487735","https://openalex.org/W4390645941","https://openalex.org/W2617764165","https://openalex.org/W7221114923","https://openalex.org/W3161861914","https://openalex.org/W4417357438","https://openalex.org/W4284674258","https://openalex.org/W3046241697","https://openalex.org/W4410255407","https://openalex.org/W2565492389"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Sarcopenia":[2],"is":[3,34,237],"defined":[4],"as":[5],"the":[6,25,29,41,111,140,176,245],"age-related":[7],"progressive":[8],"loss":[9],"of":[10,27,31,66,92,119,170,248],"skeletal":[11,186],"muscle":[12,53,55,187],"mass,":[13,54],"strength,":[14,56],"and":[15,47,57,69,78,89,100,102,126,132,148,151,194,204,219,225],"function.":[16],"Although":[17],"many":[18,216],"different":[19,42],"interventions":[20,43,83,182,213],"have":[21],"been":[22],"suggested":[23],"for":[24,74,116,168],"management":[26],"sarcopenia,":[28],"effectiveness":[30],"such":[32],"treatments":[33],"still":[35],"uncertain.":[36],"Objective":[37],"To":[38],"systematically":[39,72],"assess":[40],"strategies":[44],"currently":[45],"reported":[46],"to":[48,108,145,239,244],"evaluate":[49],"their":[50],"effects":[51],"on":[52,123,155],"physical":[58],"function":[59],"outcomes":[60,149,221],"in":[61,84,175,222,229],"sarcopenic":[62,223],"participants.":[63],"Methods":[64],"Web":[65],"Science,":[67],"ClinicalTrials.gov,":[68],"Scopus":[70],"were":[71,114,135,142,166,173],"searched":[73],"exercise,":[75],"nutritional,":[76],"pharmacological,":[77],"other":[79,232],"randomised":[80],"controlled":[81],"trial":[82],"participants":[85],"diagnosed":[86],"with":[87,231,250],"sarcopenia":[88],"\u226550":[90],"years":[91],"age.":[93],"Eligibility":[94],"was":[95,106,121,153],"assessed":[96,167],"through":[97],"reviewing":[98],"titles":[99],"abstracts,":[101],"if":[103],"a":[104],"study":[105],"found":[107],"be":[109],"eligible":[110],"full":[112],"texts":[113],"read":[115],"confirmation.":[117],"Risk":[118],"bias":[120],"performed":[122,154],"included":[124,174],"studies":[125,141,249],"subsequently":[127],"data":[128],"including":[129],"study,":[130],"participant,":[131],"intervention":[133,146],"characteristics,":[134],"extracted.":[136],"Using":[137],"this":[138],"data,":[139],"subgrouped":[143],"according":[144],"type":[147],"reported,":[150],"meta-analysis":[152],"exercise":[156,181],"interventions.":[157],"Results":[158],"Database":[159],"searching":[160],"retrieved":[161],"2558":[162],"records.":[163],"21":[164],"full-texts":[165],"eligibility,":[169],"which":[171],"7":[172],"meta-analysis.":[177],"Meta-analysis":[178],"revealed":[179],"that":[180],"significantly":[183,214],"improved":[184,215],"appendicular":[185],"mass":[188],"(0.5kg,":[189],"0.09-0.91CI,":[190],"P=0.02),":[191,203],"timed":[192],"up":[193],"go":[195],"(-1.67s,":[196],"-2.43--0.91CI,":[197],"P<0.0001),":[198],"grip":[199],"strength":[200,207],"(2.04kg,":[201],"0.39-3.70CI,":[202],"knee":[205],"extension":[206],"(12.35Nm,":[208],"8.47-16.23CI,":[209],"P<00001).":[210],"Conclusion":[211],"Exercise":[212],"body":[217],"composition":[218],"functional":[220],"participants,":[224],"these":[226,241],"results":[227],"are":[228],"line":[230],"reviews,":[233],"however":[234],"further":[235],"research":[236],"required":[238],"consolidate":[240],"findings":[242],"due":[243],"small":[246],"number":[247],"heterogeneous":[251],"methods.":[252]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-07-23T00:00:00"}