{"id":"https://openalex.org/W4384941785","doi":"https://doi.org/10.1016/s0168-8278(23)02126-8","title":"Novel role of macrophage Foxo1-mediated YAP-Notch axis in NASH progression","display_name":"Novel role of macrophage Foxo1-mediated YAP-Notch axis in NASH progression","publication_year":2023,"publication_date":"2023-06-01","ids":{"openalex":"https://openalex.org/W4384941785","doi":"https://doi.org/10.1016/s0168-8278(23)02126-8"},"language":"en","primary_location":{"id":"doi:10.1016/s0168-8278(23)02126-8","doi":"https://doi.org/10.1016/s0168-8278(23)02126-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0168-8278(23)02126-8","pdf_url":null,"source":{"id":"https://openalex.org/S83651209","display_name":"Journal of Hepatology","issn_l":"0168-8278","issn":["0168-8278","1600-0641"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hepatology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079724026","display_name":"Dongwei Xu","orcid":"https://orcid.org/0000-0001-9802-0664","observed_orcids":["https://orcid.org/0000-0001-9802-0664"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dongwei Xu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080668711","display_name":"Xiaoye Qu","orcid":"https://orcid.org/0000-0003-3983-9332","observed_orcids":["https://orcid.org/0000-0003-3983-9332"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaoye Qu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100780751","display_name":"Tao Yang","orcid":"https://orcid.org/0000-0002-1127-9364","observed_orcids":["https://orcid.org/0000-0002-1127-9364"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tao Yang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100411501","display_name":"Xiao Wang","orcid":"https://orcid.org/0000-0002-9647-8847","observed_orcids":["https://orcid.org/0000-0002-9647-8847"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiao Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067220739","display_name":"Michael Ke","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Ke","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100361663","display_name":"Jun Li","orcid":"https://orcid.org/0000-0001-7218-429X","observed_orcids":["https://orcid.org/0000-0001-7218-429X","https://orcid.org/0000-0001-9880-1356"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jun Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111888804","display_name":"Longfeng Jiang","orcid":"https://orcid.org/0000-0001-8058-6838","observed_orcids":["https://orcid.org/0000-0001-8058-6838"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Longfeng Jiang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085075008","display_name":"Qiang Xia","orcid":"https://orcid.org/0000-0001-9482-6951","observed_orcids":["https://orcid.org/0000-0001-9482-6951"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qiang Xia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068321792","display_name":"Douglas G. Farmer","orcid":"https://orcid.org/0000-0001-9080-0527","observed_orcids":["https://orcid.org/0000-0001-9080-0527"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Douglas Farmer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5045209569","display_name":"Bibo Ke","orcid":"https://orcid.org/0000-0002-1885-1538","observed_orcids":["https://orcid.org/0000-0002-1885-1538"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bibo Ke","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4950,"currency":"USD","value_usd":4950},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.12966382,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"78","issue":null,"first_page":"S730","last_page":"S731"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.5590999722480774,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.5590999722480774,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.2531999945640564,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12065","display_name":"Hippo pathway signaling and YAP/TAZ","score":0.06030000001192093,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-alcoholic-steatohepatitis","display_name":"nonalcoholic steatohepatitis","score":0.8870000243186951},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.9350000023841858},{"id":"https://openalex.org/keywords/foxo1","display_name":"FOXO1","score":0.9769999980926514},{"id":"https://openalex.org/keywords/yap","display_name":"YAP","score":0.9639999866485596},{"id":"https://openalex.org/keywords/notch-signaling","display_name":"Notch signaling","score":0.9890000224113464},{"id":"https://openalex.org/keywords/nash-progression","display_name":"NASH progression","score":0.7390000224113464},{"id":"https://openalex.org/keywords/liver-inflammation","display_name":"liver inflammation","score":0.5839999914169312}],"concepts":[{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.5497137904167175},{"id":"https://openalex.org/C140149449","wikidata":"https://www.wikidata.org/wiki/Q17928793","display_name":"FOXO1","level":4,"score":0.4622243642807007},{"id":"https://openalex.org/C161879069","wikidata":"https://www.wikidata.org/wiki/Q904082","display_name":"Notch signaling pathway","level":3,"score":0.4611636996269226},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.405128538608551},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.251451313495636},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.15615680813789368},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13371723890304565},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0168-8278(23)02126-8","doi":"https://doi.org/10.1016/s0168-8278(23)02126-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0168-8278(23)02126-8","pdf_url":null,"source":{"id":"https://openalex.org/S83651209","display_name":"Journal of Hepatology","issn_l":"0168-8278","issn":["0168-8278","1600-0641"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hepatology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/2","score":0.6200000047683716,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4401473394","https://openalex.org/W4255073245","https://openalex.org/W3179088870","https://openalex.org/W4283822121","https://openalex.org/W3185805807","https://openalex.org/W4283817307","https://openalex.org/W2901663946","https://openalex.org/W4283808831","https://openalex.org/W6903112604","https://openalex.org/W4317936938"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-09T09:14:12.587421","created_date":"2023-07-22T00:00:00"}